adisease

Showing entry for Bradykinesia

General Disease Information
BXGD Id	BXGD004590
Disease Name	Bradykinesia
Disease CUI Id	C0233565
MeSH Codes	C23 C10
Disease Class Name	Pathological Conditions, Signs and Symptoms; Nervous System Diseases
Semantic Type	Sign or Symptom
Human Phenotype Ontology Id	HP:0000707
Human Phenotype Ontology Term	Abnormality of the nervous system
Disease Ontology Id
Disease Ontology Class Name
Disorder Network	disorder-protein-compound-food associations

The disease-related target proteins

Proteins

Uniport Id	BXGT Id	Protein Name	Gene	Status	Protein Class
Uniport Id	BXGT Id	Protein name	Gene	Status	Protein class
F7VJQ1	BXGT003310	Alternative prion protein	5621	reviewed
O00142	BXGT003883	Thymidine kinase 2, mitochondrial	7084	reviewed	Kinase
O14764	BXGT004094	Gamma-aminobutyric acid receptor subunit delta	2563	reviewed	Ion channel
O43464	BXGT004595	Serine protease HTRA2, mitochondrial	27429	reviewed
O60260	BXGT004864	E3 ubiquitin-protein ligase parkin	5071	reviewed	Enzyme
O60741	BXGT004897	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1	348980	reviewed
O95263	BXGT005366	High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B	8622	reviewed
O95363	BXGT005375	Phenylalanine--tRNA ligase, mitochondrial	10667	reviewed	Enzyme
P00326	BXGT005499	Alcohol dehydrogenase 1C	126	reviewed	Enzyme
P02649	BXGT005909	Apolipoprotein E	348	reviewed
P02792	BXGT005966	Ferritin light chain	2512	reviewed	Storage
P04062	BXGT006140	Lysosomal acid glucosylceramidase	2629	reviewed
P04156	BXGT006156	Major prion protein	5621	reviewed
P04179	BXGT006163	Superoxide dismutase [Mn], mitochondrial	6648	reviewed	Enzyme
P05090	BXGT006311	Apolipoprotein D	347	reviewed
P05177	BXGT006336	Cytochrome P450 1A2	1544	reviewed	Enzyme
P06753	BXGT006498	Tropomyosin alpha-3 chain	7170	reviewed	Cellular structure
P07101	BXGT006547	Tyrosine 3-monooxygenase	7054	reviewed
P07333	BXGT006602	Macrophage colony-stimulating factor 1 receptor	1436	reviewed	Kinase
P09619	BXGT006911	Platelet-derived growth factor receptor beta	5159	reviewed	Kinase
P09936	BXGT006943	Ubiquitin carboxyl-terminal hydrolase isozyme L1	7345	reviewed	Enzyme
P10636	BXGT007596	Microtubule-associated protein tau	4137	reviewed
P12235	BXGT007774	ADP/ATP translocase 1	291	reviewed	Transporter
P13637	BXGT007933	Sodium/potassium-transporting ATPase subunit alpha-3	478	reviewed	Transporter
P14416	BXGT008011	D(2) dopamine receptor	1813	reviewed	G-protein coupled receptor
P15559	BXGT008139	NAD(P)H dehydrogenase [quinone] 1	1728	reviewed
P18507	BXGT008411	Gamma-aminobutyric acid receptor subunit gamma-2	2566	reviewed	Ion channel
P21399	BXGT008646	Cytoplasmic aconitate hydratase	48	reviewed	Enzyme
P21675	BXGT008678	Transcription initiation factor TFIID subunit 1	6872	reviewed	Kinase
P21917	BXGT008707	D(4) dopamine receptor	1815	reviewed	G-protein coupled receptor
P28335	BXGT009255	5-hydroxytryptamine receptor 2C	3358	reviewed	G-protein coupled receptor
P30793	BXGT009466	GTP cyclohydrolase 1	2643	reviewed	Enzyme
P35270	BXGT009807	Sepiapterin reductase	6697	reviewed
P35498	BXGT009838	Sodium channel protein type 1 subunit alpha	6323	reviewed	Ion channel
P37840	BXGT010015	Alpha-synuclein	6622	reviewed	Transporter
P41146	BXGT010226	Nociceptin receptor	4987	reviewed	G-protein coupled receptor
P42858	BXGT010341	Huntingtin	3064	reviewed
P43354	BXGT010381	Nuclear receptor subfamily 4 group A member 2	4929	reviewed	Nuclear receptor
P49448	BXGT010709	Glutamate dehydrogenase 2, mitochondrial	2747	reviewed	Enzyme
P49768	BXGT010740	Presenilin-1	5663	reviewed	Enzyme
P52758	BXGT010951	2-iminobutanoate/2-iminopropanoate deaminase	10247	reviewed
P54098	BXGT011030	DNA polymerase subunit gamma-1	5428	reviewed	Enzyme
P62258	BXGT011415	14-3-3 protein epsilon	7531	reviewed	Chaperone
P68133	BXGT011578	Actin, alpha skeletal muscle	58	reviewed	Cellular structure
P78330	BXGT011833	Phosphoserine phosphatase	5723	reviewed	Enzyme
P98164	BXGT012230	Low-density lipoprotein receptor-related protein 2	4036	reviewed
Q01959	BXGT012624	Sodium-dependent dopamine transporter	6531	reviewed	Transporter
Q03393	BXGT012711	6-pyruvoyl tetrahydrobiopterin synthase	5805	reviewed
Q04637	BXGT012771	Eukaryotic translation initiation factor 4 gamma 1	1981	reviewed	Nucleic acid binding
Q05940	BXGT012846	Synaptic vesicular amine transporter	6571	reviewed	Transporter
Q06787	BXGT012890	Synaptic functional regulator FMR1	2332	reviewed	Nucleic acid binding
Q12879	BXGT013275	Glutamate receptor ionotropic, NMDA 2A	2903	reviewed	Ion channel
Q13224	BXGT013328	Glutamate receptor ionotropic, NMDA 2B	2904	reviewed	Ion channel
Q14003	BXGT013434	Potassium voltage-gated channel subfamily C member 3	3748	reviewed	Ion channel
Q14203	BXGT013455	Dynactin subunit 1	1639	reviewed	Chaperone
Q15858	BXGT013610	Sodium channel protein type 9 subunit alpha	6335	reviewed	Ion channel
Q5JPH6	BXGT015456	Probable glutamate--tRNA ligase, mitochondrial	124454	reviewed	Enzyme
Q5S007	BXGT015650	Leucine-rich repeat serine/threonine-protein kinase 2	120892	reviewed	Kinase
Q6N021	BXGT016378	Methylcytosine dioxygenase TET2	54790	reviewed
Q7LG56	BXGT016999	Ribonucleoside-diphosphate reductase subunit M2 B	50484	reviewed	Enzyme
Q8WXF7	BXGT019011	Atlastin-1	51062	reviewed	Enzyme modulator
Q96QK1	BXGT019720	Vacuolar protein sorting-associated protein 35	55737	reviewed	Transporter
Q99250	BXGT019913	Sodium channel protein type 2 subunit alpha	6326	reviewed	Ion channel
Q99497	BXGT019926	Protein/nucleic acid deglycase DJ-1	11315	reviewed	Enzyme
Q99700	BXGT019949	Ataxin-2	6311	reviewed	Nucleic acid binding
Q9BUF5	BXGT020135	Tubulin beta-6 chain	84617	reviewed	Cellular structure
Q9BXM7	BXGT020172	Serine/threonine-protein kinase PINK1, mitochondrial	65018	reviewed	Kinase
Q9BZ23	BXGT020194	Pantothenate kinase 2, mitochondrial	80025	reviewed	Kinase
Q9Y3I1	BXGT022260	F-box only protein 7	25793	reviewed
Q9Y4W6	BXGT025025	AFG3-like protein 2	10939	reviewed	Enzyme
Q96DA2	BXGT025522	Ras-related protein Rab-39B	116442	reviewed
Q86SQ9	BXGT025875	Dehydrodolichyl diphosphate synthase complex subunit DHDDS	79947	reviewed	Enzyme

The disease-related compounds

Compounds

BXGC Id	Compound Name	Structure	Molecular Weight	Number of targets^{?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease}

The disease-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compounds in food^{?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease}