Showing entry for ATP-dependent translocase ABCB1


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT008651
Protein NameATP-dependent translocase ABCB1
Uniport IdP21447
GeneAbcb1a
Gene Id18671
DomainABC_membrane; ABC_tran
Pfam PF00664   PF00005  
OrganismMus musculus (Mouse)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0033231 carbohydrate export
Biological Process GO:0099040 ceramide translocation
Biological Process GO:0043215 daunorubicin transport
Biological Process GO:0060856 establishment of blood-brain barrier
Biological Process GO:1990963 establishment of blood-retinal barrier
Biological Process GO:0140115 export across plasma membrane
Biological Process GO:0000086 G2/M transition of mitotic cell cycle
Biological Process GO:0009914 hormone transport
Biological Process GO:0050892 intestinal absorption
Biological Process GO:0035633 maintenance of blood-brain barrier
Biological Process GO:0060548 negative regulation of cell death
Biological Process GO:0045332 phospholipid translocation
Biological Process GO:1901529 positive regulation of anion channel activity
Biological Process GO:1904446 positive regulation of establishment of Sertoli cell barrier
Biological Process GO:2001025 positive regulation of response to drug
Biological Process GO:1902396 protein localization to bicellular tight junction
Biological Process GO:2001225 regulation of chloride transport
Biological Process GO:1904478 regulation of intestinal absorption
Biological Process GO:0047484 regulation of response to osmotic stress
Biological Process GO:0072089 stem cell proliferation
Biological Process GO:0070633 transepithelial transport
Biological Process GO:0055085 transmembrane transport
Biological Process GO:1990961 xenobiotic detoxification by transmembrane export across the plasma membrane
Biological Process GO:1990962 xenobiotic transport across blood-brain barrier
molecular function GO:0016887 ATPase activity
molecular function GO:0042626 ATPase-coupled transmembrane transporter activity
molecular function GO:0008559 ATPase-coupled xenobiotic transmembrane transporter activity
molecular function GO:0005524 ATP binding
molecular function GO:0099038 ceramide floppase activity
molecular function GO:0015562 efflux transmembrane transporter activity
molecular function GO:0140328 floppase activity
molecular function GO:0090554 phosphatidylcholine floppase activity
molecular function GO:0090555 phosphatidylethanolamine flippase activity
molecular function GO:0031625 ubiquitin protein ligase binding
molecular function GO:0042910 xenobiotic transmembrane transporter activity
cellular component GO:0045177 apical part of cell
cellular component GO:0016324 apical plasma membrane
cellular component GO:0031526 brush border membrane
cellular component GO:0009986 cell surface
cellular component GO:0016021 integral component of membrane
cellular component GO:0046581 intercellular canaliculus
cellular component GO:0016020 membrane
cellular component GO:0005886 plasma membrane
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000340 Kaempferol 286.24
BXGC0000363 Galangin 270.24
BXGC0000383 (S)-Naringenin 272.25
BXGC0001325 Progesterone 314.46
BXGC0001789 Silibinin 482.44
BXGC0002692 Arsenic 77.95
BXGC0002867 Lappaurin 284.74
BXGC0008840 Kaempferide 300.26
BXGC0011323 2,3-Dehydrosilybin 480.42
BXGC0016891 Nortriptyline 263.17
BXGC0022231 Ursodiol 392.29
BXGC0022544 Digoxin 780.43
BXGC0024141 Hydrocortisone 362.21
BXGC0025658 Vinblastine 810.42
BXGC0027421 Paclitaxel 853.33
BXGC0030138 Colchicine 399.17
BXGC0030901 Morphine 285.14
BXGC0031618 Vinblastine 810.42
BXGC0034768 Vincristine 824.4
BXGC0034783 Doxorubicin 543.17
BXGC0035201 Quinidine 324.18
BXGC0043125 Taxifolin 304.06
BXGC0043126 Nicardipine 479.21
BXGC0044017 Verapamil 454.28
BXGC0046862 Benzo[Def]Chrysene 252.09
BXGC0052374 Reserpine 608.27
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein