Showing entry for Colchicine


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Compound Information
BXGC IdBXGC0030138
Compound NameColchicine
Structure
FormulaC22H25NO6
InchiKeyIAKHMKGGTNLKSZ-INIZCTEOSA-N
SMILESCOc1c(OC)cc2c(c1OC)c1ccc(c(=O)cc1[C@H](CC2)N=C(O)C)OC
InchiInChI=1S/C22H25NO6/c1-12(24)23-16-8-6-13-10-19(27-3)21(28-4)22(29-5)20(13)14-7-9-18(26-2)17(25)11-15(14)16/h7,9-11,16H,6,8H2,1-5H3,(H,23,24)/t16-/m0/s1
IUPACN-[(7S)-1,2,3,10-tetramethoxy-9-oxo-6,7-dihydro-5H-benzo[a]heptalen-7-yl]acetamide
Molecular Weight399.17
Pubchem Id6167
Chembl IdCHEMBL107
Targets of Information Source
DrugBank n.a
Uniport Id BXGT Id Protein Name Status Protein Class Gene Groups Target Type
Uniport Id BXGT Id Protein Name Status Protein Class Gene Groups Target Type
PDB LOC
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM Ka M-1
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM Ka M-1
Q6B856 BXGT016212 Tubulin beta-2B chain reviewed TUBB2B - - - - -
D0VWY9 BXGT002752 Tubulin beta chain unreviewed - - - - -
O60885 BXGT004906 Bromodomain-containing protein 4 reviewed BRD4 Epigenetic regulator - - 20000 -
Q6B856 BXGT016212 Tubulin beta-2B chain reviewed TUBB2B - - 1400 - -
P80188 BXGT011882 Neutrophil gelatinase-associated lipocalin reviewed LCN2 Enzyme - - 0.12 -
P02554 BXGT005892 Tubulin beta chain reviewed - - - - -
O60885 BXGT004906 Bromodomain-containing protein 4 reviewed BRD4 Epigenetic regulator - - - -
Binding DB 50014846
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM EC50 nM
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM EC50 nM
reviewed BXGT010897 Nuclear receptor subfamily 0 group B member 1 reviewed Nuclear receptor NR0B1 - >67568 - -
reviewed BXGT013335 Steroidogenic factor 1 reviewed Nuclear receptor NR5A1 - >67568 - -
reviewed BXGT016212 Tubulin beta-2B chain reviewed TUBB2B - 800 - -
reviewed BXGT016212 Tubulin beta-2B chain reviewed TUBB2B - 11200000 - -
reviewed BXGT013938 Tubulin polymerization-promoting protein reviewed TPPP - - - 750
reviewed BXGT005891 Tubulin alpha-1A chain reviewed TUBA1A - 800 - -
reviewed BXGT016212 Tubulin beta-2B chain reviewed TUBB2B - 1700 - -
reviewed BXGT013373 Histone deacetylase 1 reviewed Epigenetic regulator HDAC1 - >20 - -
reviewed BXGT019370 Histone deacetylase 2 reviewed Epigenetic regulator HDAC2 - >20 - -
reviewed BXGT004159 Histone deacetylase 3 reviewed Epigenetic regulator HDAC3 - >20 - -
reviewed BXGT016212 Tubulin beta-2B chain reviewed TUBB2B - 2620 - -
reviewed BXGT016212 Tubulin beta-2B chain reviewed TUBB2B - 1900 - -
reviewed BXGT005891 Tubulin alpha-1A chain reviewed TUBA1A 2500 - - -
reviewed BXGT005892 Tubulin beta chain reviewed - - 3790 - -
reviewed BXGT005892 Tubulin beta chain reviewed - - 10000 - -
reviewed BXGT005892 Tubulin beta chain reviewed - - 29300 - -
reviewed BXGT005892 Tubulin beta chain reviewed - 5750 - - -
reviewed BXGT005891 Tubulin alpha-1A chain reviewed TUBA1A - 1500 - -
reviewed BXGT016212 Tubulin beta-2B chain reviewed TUBB2B - 3500 - -
reviewed BXGT005891 Tubulin alpha-1A chain reviewed TUBA1A - 1900 - -
reviewed BXGT016212 Tubulin beta-2B chain reviewed TUBB2B 780 - - -
reviewed BXGT016212 Tubulin beta-2B chain reviewed TUBB2B - 2400 - -
reviewed BXGT008651 ATP-dependent translocase ABCB1 reviewed Abcb1a - >50000 - -
reviewed BXGT006741 ATP-dependent translocase ABCB1 reviewed Transporter ABCB1 - >50000 - -
reviewed BXGT006812 Cytochrome P450 3A4 reviewed Enzyme CYP3A4 - >50000 - -
reviewed BXGT006507 ATP-dependent translocase ABCB1 reviewed Abcb1b - >50000 - -
reviewed BXGT005891 Tubulin alpha-1A chain reviewed TUBA1A - 4168.69 - -
reviewed BXGT005150 Solute carrier family 22 member 3 reviewed Transporter SLC22A3 120 - - -
CHEMBL CHEMBL107
Uniport Id BXGT Id Protein Name Status Protein Class Gene width="10%">Type Relation value Units
Uniport Id BXGT Id Protein Name Status Protein Class Gene Type Relation value Units
Q9BUF5 BXGT020135 Tubulin beta-6 chain reviewed Cellular structure TUBB6 IC50 '=' 1700 nM
Q9BVA1 BXGT020142 Tubulin beta-2B chain reviewed - TUBB2B IC50 '=' 1700 nM
Q13885 BXGT013400 Tubulin beta-2A chain reviewed Cellular structure TUBB2A IC50 '=' 1700 nM
Q6PEY2 BXGT016465 Tubulin alpha-3E chain reviewed Cellular structure TUBA3E IC50 '=' 1700 nM
Q9BQE3 BXGT020109 Tubulin alpha-1C chain reviewed Cellular structure TUBA1C IC50 '=' 1700 nM
P68363 BXGT011594 Tubulin alpha-1B chain reviewed Cellular structure TUBA1B IC50 '=' 1700 nM
P07437 BXGT006624 Tubulin beta chain reviewed Cellular structure TUBB IC50 '=' 1700 nM
Q3ZCM7 BXGT014551 Tubulin beta-8 chain reviewed - TUBB8 IC50 '=' 1700 nM
P04350 BXGT006193 Tubulin beta-4A chain reviewed Cellular structure TUBB4A IC50 '=' 1700 nM
Q71U36 BXGT016705 Tubulin alpha-1A chain reviewed Cellular structure TUBA1A IC50 '=' 1700 nM
Q13509 BXGT013366 Tubulin beta-3 chain reviewed Cellular structure TUBB3 IC50 '=' 1700 nM
P68366 BXGT011595 Tubulin alpha-4A chain reviewed Cellular structure TUBA4A IC50 '=' 1700 nM
P0DPH7 BXGT007527 Tubulin alpha-3C chain reviewed - TUBA3C IC50 '=' 1700 nM
Q9H4B7 BXGT020475 Tubulin beta-1 chain reviewed Cellular structure TUBB1 IC50 '=' 1700 nM
P68371 BXGT011597 Tubulin beta-4B chain reviewed Cellular structure TUBB4B IC50 '=' 1700 nM
P02550 BXGT005891 Tubulin alpha-1A chain reviewed - TUBA1A Ki '=' 1 nM
P02554 BXGT005892 Tubulin beta chain reviewed - Ki '=' 1 nM
Q92887 BXGT019389 Canalicular multispecific organic anion transporter 1 reviewed Transporter ABCC2 Activity '=' 101 %
P25094 BXGT009014 Peripheral myelin protein 22 reviewed - Pmp22 Potency - 101 nM
P28335 BXGT009255 5-hydroxytryptamine receptor 2C reviewed G-protein coupled receptor HTR2C Ki - - -
P02550 BXGT005891 Tubulin alpha-1A chain reviewed - TUBA1A IC50 '=' 1400 nM
P02554 BXGT005892 Tubulin beta chain reviewed - IC50 '=' 1400 nM
O75496 BXGT005132 Geminin reviewed - GMNN Potency - 33 nM
P08183 BXGT006741 ATP-dependent translocase ABCB1 reviewed Transporter ABCB1 IC50 '>' 50000 nM
P02550 BXGT005891 Tubulin alpha-1A chain reviewed - TUBA1A Inhibitory binding '=' 100 %
P33261 BXGT009707 Cytochrome P450 2C19 reviewed - CYP2C19 Inhibition - - -
P10632 BXGT007592 Cytochrome P450 2C8 reviewed - CYP2C8 Inhibition '=' 20 %
P35367 BXGT009821 Histamine H1 receptor reviewed G-protein coupled receptor HRH1 IC50 - - -
A6XA80 BXGT001522 Leukotriene C4 synthase reviewed - LTC4S IC50 - - -
P02550 BXGT005891 Tubulin alpha-1A chain reviewed - TUBA1A Inhibition - - -
P02554 BXGT005892 Tubulin beta chain reviewed - Inhibition - - -
Q9BUF5 BXGT020135 Tubulin beta-6 chain reviewed Cellular structure TUBB6 Inhibition '=' 34 %
Q9BVA1 BXGT020142 Tubulin beta-2B chain reviewed - TUBB2B Inhibition '=' 34 %
Q13885 BXGT013400 Tubulin beta-2A chain reviewed Cellular structure TUBB2A Inhibition '=' 34 %
Q6PEY2 BXGT016465 Tubulin alpha-3E chain reviewed Cellular structure TUBA3E Inhibition '=' 34 %
Q9BQE3 BXGT020109 Tubulin alpha-1C chain reviewed Cellular structure TUBA1C Inhibition '=' 34 %
P68363 BXGT011594 Tubulin alpha-1B chain reviewed Cellular structure TUBA1B Inhibition '=' 34 %
P07437 BXGT006624 Tubulin beta chain reviewed Cellular structure TUBB Inhibition '=' 34 %
Q3ZCM7 BXGT014551 Tubulin beta-8 chain reviewed - TUBB8 Inhibition '=' 34 %
P04350 BXGT006193 Tubulin beta-4A chain reviewed Cellular structure TUBB4A Inhibition '=' 34 %
Q71U36 BXGT016705 Tubulin alpha-1A chain reviewed Cellular structure TUBA1A Inhibition '=' 34 %
Q13509 BXGT013366 Tubulin beta-3 chain reviewed Cellular structure TUBB3 Inhibition '=' 34 %
P68366 BXGT011595 Tubulin alpha-4A chain reviewed Cellular structure TUBA4A Inhibition '=' 34 %
P0DPH7 BXGT007527 Tubulin alpha-3C chain reviewed - TUBA3C Inhibition '=' 34 %
Q9H4B7 BXGT020475 Tubulin beta-1 chain reviewed Cellular structure TUBB1 Inhibition '=' 34 %
P68371 BXGT011597 Tubulin beta-4B chain reviewed Cellular structure TUBB4B Inhibition '=' 34 %
P02550 BXGT005891 Tubulin alpha-1A chain reviewed - TUBA1A IC50 '=' 2500 nM
P02554 BXGT005892 Tubulin beta chain reviewed - IC50 '=' 2500 nM
P02550 BXGT005891 Tubulin alpha-1A chain reviewed - TUBA1A IC50 '=' 1900 nM
P21447 BXGT008651 ATP-dependent translocase ABCB1 reviewed - Abcb1a Ratio '=' 1 -
Q862F3 BXGT017581 Similar to alpha-tubulin isoform 1 unreviewed - IC50 '=' 2100 nM
Q862L2 BXGT017582 Similar to alpha-tubulin isoform 1 unreviewed - IC50 '=' 2100 nM
Q6B856 BXGT016212 Tubulin beta-2B chain reviewed - TUBB2B IC50 '=' 2100 nM
P07943 BXGT006700 Aldo-keto reductase family 1 member B1 reviewed - Akr1b1 IC50 - - -
P51681 BXGT010878 C-C chemokine receptor type 5 reviewed G-protein coupled receptor CCR5 Ki - - -
P35354 BXGT009816 Prostaglandin G/H synthase 2 reviewed Enzyme PTGS2 Ki - - -
P02550 BXGT005891 Tubulin alpha-1A chain reviewed - TUBA1A IC50 '=' 10000 nM
P02554 BXGT005892 Tubulin beta chain reviewed - IC50 '=' 10000 nM
Q862F3 BXGT017581 Similar to alpha-tubulin isoform 1 unreviewed - IC50 '=' 800 nM
Q862L2 BXGT017582 Similar to alpha-tubulin isoform 1 unreviewed - IC50 '=' 800 nM
Q6B856 BXGT016212 Tubulin beta-2B chain reviewed - TUBB2B IC50 '=' 800 nM
P12530 BXGT007827 Arachidonate 15-lipoxygenase reviewed - ALOX15 IC50 - - -
P41968 BXGT010275 Melanocortin receptor 3 reviewed G-protein coupled receptor MC3R Ki - - -
P29476 BXGT009354 Nitric oxide synthase, brain reviewed - Nos1 Ki - - -
P29477 BXGT009355 Nitric oxide synthase, inducible reviewed - Nos2 IC50 - - -
P06239 BXGT006427 Tyrosine-protein kinase Lck reviewed Kinase LCK IC50 - - -
Q862F3 BXGT017581 Similar to alpha-tubulin isoform 1 unreviewed - IC50 '=' 8700 nM
Q862L2 BXGT017582 Similar to alpha-tubulin isoform 1 unreviewed - IC50 '=' 8700 nM
Q6B856 BXGT016212 Tubulin beta-2B chain reviewed - TUBB2B IC50 '=' 8700 nM
Q9Y6L6 BXGT022334 Solute carrier organic anion transporter family member 1B1 reviewed Transporter SLCO1B1 Inhibition '=' 75 %
Q06710 BXGT012887 Paired box protein Pax-8 reviewed - PAX8 AC50 '<' 260 nM
P02550 BXGT005891 Tubulin alpha-1A chain reviewed - TUBA1A Inhibition '=' 52 %
P02554 BXGT005892 Tubulin beta chain reviewed - Inhibition '=' 52 %
Q9Y6L6 BXGT022334 Solute carrier organic anion transporter family member 1B1 reviewed Transporter SLCO1B1 Inhibition '=' 45 %
P40225 BXGT010168 Thrombopoietin reviewed - THPO Potency '=' 501 nM
P25105 BXGT009021 Platelet-activating factor receptor reviewed G-protein coupled receptor PTAFR Ki - - -
P27361 BXGT009176 Mitogen-activated protein kinase 3 reviewed Kinase MAPK3 Ki - - -
P11712 BXGT007738 Cytochrome P450 2C9 reviewed - CYP2C9 Ki - - -
P21728 BXGT008686 D(1A) dopamine receptor reviewed G-protein coupled receptor DRD1 IC50 - - -
Q01959 BXGT012624 Sodium-dependent dopamine transporter reviewed Transporter SLC6A3 Ki - - -
P03372 BXGT006059 Estrogen receptor reviewed Nuclear receptor ESR1 Ki - - -
Q92731 BXGT019366 Estrogen receptor beta reviewed Nuclear receptor ESR2 Ki - - -
Q9BUF5 BXGT020135 Tubulin beta-6 chain reviewed Cellular structure TUBB6 Inhibition '=' 72 %
Q9BVA1 BXGT020142 Tubulin beta-2B chain reviewed - TUBB2B Inhibition '=' 72 %
Q13885 BXGT013400 Tubulin beta-2A chain reviewed Cellular structure TUBB2A Inhibition '=' 72 %
Q6PEY2 BXGT016465 Tubulin alpha-3E chain reviewed Cellular structure TUBA3E Inhibition '=' 72 %
Q9BQE3 BXGT020109 Tubulin alpha-1C chain reviewed Cellular structure TUBA1C Inhibition '=' 72 %
P68363 BXGT011594 Tubulin alpha-1B chain reviewed Cellular structure TUBA1B Inhibition '=' 72 %
P07437 BXGT006624 Tubulin beta chain reviewed Cellular structure TUBB Inhibition '=' 72 %
Q3ZCM7 BXGT014551 Tubulin beta-8 chain reviewed - TUBB8 Inhibition '=' 72 %
P04350 BXGT006193 Tubulin beta-4A chain reviewed Cellular structure TUBB4A Inhibition '=' 72 %
Q71U36 BXGT016705 Tubulin alpha-1A chain reviewed Cellular structure TUBA1A Inhibition '=' 72 %
Q13509 BXGT013366 Tubulin beta-3 chain reviewed Cellular structure TUBB3 Inhibition '=' 72 %
P68366 BXGT011595 Tubulin alpha-4A chain reviewed Cellular structure TUBA4A Inhibition '=' 72 %
P0DPH7 BXGT007527 Tubulin alpha-3C chain reviewed - TUBA3C Inhibition '=' 72 %
Q9H4B7 BXGT020475 Tubulin beta-1 chain reviewed Cellular structure TUBB1 Inhibition '=' 72 %
P68371 BXGT011597 Tubulin beta-4B chain reviewed Cellular structure TUBB4B Inhibition '=' 72 %
Q9BUF5 BXGT020135 Tubulin beta-6 chain reviewed Cellular structure TUBB6 EC50 - - -
Q9BVA1 BXGT020142 Tubulin beta-2B chain reviewed - TUBB2B EC50 - - -
Q13885 BXGT013400 Tubulin beta-2A chain reviewed Cellular structure TUBB2A EC50 - - -
Q6PEY2 BXGT016465 Tubulin alpha-3E chain reviewed Cellular structure TUBA3E EC50 - - -
Q9BQE3 BXGT020109 Tubulin alpha-1C chain reviewed Cellular structure TUBA1C EC50 - - -
P68363 BXGT011594 Tubulin alpha-1B chain reviewed Cellular structure TUBA1B EC50 - - -
P07437 BXGT006624 Tubulin beta chain reviewed Cellular structure TUBB EC50 - - -
Q3ZCM7 BXGT014551 Tubulin beta-8 chain reviewed - TUBB8 EC50 - - -
P04350 BXGT006193 Tubulin beta-4A chain reviewed Cellular structure TUBB4A EC50 - - -
Q71U36 BXGT016705 Tubulin alpha-1A chain reviewed Cellular structure TUBA1A EC50 - - -
Q13509 BXGT013366 Tubulin beta-3 chain reviewed Cellular structure TUBB3 EC50 - - -
P68366 BXGT011595 Tubulin alpha-4A chain reviewed Cellular structure TUBA4A EC50 - - -
P0DPH7 BXGT007527 Tubulin alpha-3C chain reviewed - TUBA3C EC50 - - -
Q9H4B7 BXGT020475 Tubulin beta-1 chain reviewed Cellular structure TUBB1 EC50 - - -
P68371 BXGT011597 Tubulin beta-4B chain reviewed Cellular structure TUBB4B EC50 - - -
Q9BUF5 BXGT020135 Tubulin beta-6 chain reviewed Cellular structure TUBB6 Inhibition '=' 77 %
Q9BVA1 BXGT020142 Tubulin beta-2B chain reviewed - TUBB2B Inhibition '=' 77 %
Q13885 BXGT013400 Tubulin beta-2A chain reviewed Cellular structure TUBB2A Inhibition '=' 77 %
Q6PEY2 BXGT016465 Tubulin alpha-3E chain reviewed Cellular structure TUBA3E Inhibition '=' 77 %
Q9BQE3 BXGT020109 Tubulin alpha-1C chain reviewed Cellular structure TUBA1C Inhibition '=' 77 %
P68363 BXGT011594 Tubulin alpha-1B chain reviewed Cellular structure TUBA1B Inhibition '=' 77 %
P07437 BXGT006624 Tubulin beta chain reviewed Cellular structure TUBB Inhibition '=' 77 %
Q3ZCM7 BXGT014551 Tubulin beta-8 chain reviewed - TUBB8 Inhibition '=' 77 %
P04350 BXGT006193 Tubulin beta-4A chain reviewed Cellular structure TUBB4A Inhibition '=' 77 %
Q71U36 BXGT016705 Tubulin alpha-1A chain reviewed Cellular structure TUBA1A Inhibition '=' 77 %
Q13509 BXGT013366 Tubulin beta-3 chain reviewed Cellular structure TUBB3 Inhibition '=' 77 %
P68366 BXGT011595 Tubulin alpha-4A chain reviewed Cellular structure TUBA4A Inhibition '=' 77 %
P0DPH7 BXGT007527 Tubulin alpha-3C chain reviewed - TUBA3C Inhibition '=' 77 %
Q9H4B7 BXGT020475 Tubulin beta-1 chain reviewed Cellular structure TUBB1 Inhibition '=' 77 %
P68371 BXGT011597 Tubulin beta-4B chain reviewed Cellular structure TUBB4B Inhibition '=' 77 %
Q9BUF5 BXGT020135 Tubulin beta-6 chain reviewed Cellular structure TUBB6 Inhibition '=' 21 %
Q9BVA1 BXGT020142 Tubulin beta-2B chain reviewed - TUBB2B Inhibition '=' 21 %
Q13885 BXGT013400 Tubulin beta-2A chain reviewed Cellular structure TUBB2A Inhibition '=' 21 %
Q6PEY2 BXGT016465 Tubulin alpha-3E chain reviewed Cellular structure TUBA3E Inhibition '=' 21 %
Q9BQE3 BXGT020109 Tubulin alpha-1C chain reviewed Cellular structure TUBA1C Inhibition '=' 21 %
P68363 BXGT011594 Tubulin alpha-1B chain reviewed Cellular structure TUBA1B Inhibition '=' 21 %
P07437 BXGT006624 Tubulin beta chain reviewed Cellular structure TUBB Inhibition '=' 21 %
Q3ZCM7 BXGT014551 Tubulin beta-8 chain reviewed - TUBB8 Inhibition '=' 21 %
P04350 BXGT006193 Tubulin beta-4A chain reviewed Cellular structure TUBB4A Inhibition '=' 21 %
Q71U36 BXGT016705 Tubulin alpha-1A chain reviewed Cellular structure TUBA1A Inhibition '=' 21 %
Q13509 BXGT013366 Tubulin beta-3 chain reviewed Cellular structure TUBB3 Inhibition '=' 21 %
P68366 BXGT011595 Tubulin alpha-4A chain reviewed Cellular structure TUBA4A Inhibition '=' 21 %
P0DPH7 BXGT007527 Tubulin alpha-3C chain reviewed - TUBA3C Inhibition '=' 21 %
Q9H4B7 BXGT020475 Tubulin beta-1 chain reviewed Cellular structure TUBB1 Inhibition '=' 21 %
P68371 BXGT011597 Tubulin beta-4B chain reviewed Cellular structure TUBB4B Inhibition '=' 21 %
Q9NUW8 BXGT021219 Tyrosyl-DNA phosphodiesterase 1 reviewed Enzyme TDP1 Potency - 8 nM
Q9BUF5 BXGT020135 Tubulin beta-6 chain reviewed Cellular structure TUBB6 Activity - - -
Q9BVA1 BXGT020142 Tubulin beta-2B chain reviewed - TUBB2B Activity - - -
Q13885 BXGT013400 Tubulin beta-2A chain reviewed Cellular structure TUBB2A Activity - - -
Q6PEY2 BXGT016465 Tubulin alpha-3E chain reviewed Cellular structure TUBA3E Activity - - -
Q9BQE3 BXGT020109 Tubulin alpha-1C chain reviewed Cellular structure TUBA1C Activity - - -
P68363 BXGT011594 Tubulin alpha-1B chain reviewed Cellular structure TUBA1B Activity - - -
P07437 BXGT006624 Tubulin beta chain reviewed Cellular structure TUBB Activity - - -
Q3ZCM7 BXGT014551 Tubulin beta-8 chain reviewed - TUBB8 Activity - - -
P04350 BXGT006193 Tubulin beta-4A chain reviewed Cellular structure TUBB4A Activity - - -
Q71U36 BXGT016705 Tubulin alpha-1A chain reviewed Cellular structure TUBA1A Activity - - -
Q13509 BXGT013366 Tubulin beta-3 chain reviewed Cellular structure TUBB3 Activity - - -
P68366 BXGT011595 Tubulin alpha-4A chain reviewed Cellular structure TUBA4A Activity - - -
P0DPH7 BXGT007527 Tubulin alpha-3C chain reviewed - TUBA3C Activity - - -
Q9H4B7 BXGT020475 Tubulin beta-1 chain reviewed Cellular structure TUBB1 Activity - - -
P68371 BXGT011597 Tubulin beta-4B chain reviewed Cellular structure TUBB4B Activity - - -
P12530 BXGT007827 Arachidonate 15-lipoxygenase reviewed - ALOX15 Ki - - -
P33032 BXGT009689 Melanocortin receptor 5 reviewed G-protein coupled receptor MC5R Ki - - -
P08173 BXGT006738 Muscarinic acetylcholine receptor M4 reviewed G-protein coupled receptor CHRM4 IC50 - - -
Q16539 BXGT013634 Mitogen-activated protein kinase 14 reviewed Kinase MAPK14 Ki - - -
P08575 BXGT006793 Receptor-type tyrosine-protein phosphatase C reviewed Enzyme PTPRC Ki - - -
P19327 BXGT008472 5-hydroxytryptamine receptor 1A reviewed - Htr1a IC50 - - -
P28564 BXGT009272 5-hydroxytryptamine receptor 1B reviewed - Htr1b IC50 - - -
P28564 BXGT009272 5-hydroxytryptamine receptor 1B reviewed - Htr1b Ki - - -
P28223 BXGT009239 5-hydroxytryptamine receptor 2A reviewed G-protein coupled receptor HTR2A IC50 - - -
P30542 BXGT009436 Adenosine receptor A1 reviewed G-protein coupled receptor ADORA1 IC50 - - -
O94782 BXGT005332 Ubiquitin carboxyl-terminal hydrolase 1 reviewed Enzyme USP1 Potency - 25118 nM
Q6W5P4 BXGT016588 Neuropeptide S receptor reviewed - NPSR1 Potency '=' 2511 nM
O95235 BXGT005360 Kinesin-like protein KIF20A reviewed Cellular structure KIF20A IC50 - - -
P02545 BXGT005889 Prelamin-A/C reviewed - LMNA Potency '=' 8 nM
Q9BUF5 BXGT020135 Tubulin beta-6 chain reviewed Cellular structure TUBB6 IC50 '=' 3200 nM
Q9BVA1 BXGT020142 Tubulin beta-2B chain reviewed - TUBB2B IC50 '=' 3200 nM
Q13885 BXGT013400 Tubulin beta-2A chain reviewed Cellular structure TUBB2A IC50 '=' 3200 nM
Q6PEY2 BXGT016465 Tubulin alpha-3E chain reviewed Cellular structure TUBA3E IC50 '=' 3200 nM
Q9BQE3 BXGT020109 Tubulin alpha-1C chain reviewed Cellular structure TUBA1C IC50 '=' 3200 nM
P68363 BXGT011594 Tubulin alpha-1B chain reviewed Cellular structure TUBA1B IC50 '=' 3200 nM
P07437 BXGT006624 Tubulin beta chain reviewed Cellular structure TUBB IC50 '=' 3200 nM
Q3ZCM7 BXGT014551 Tubulin beta-8 chain reviewed - TUBB8 IC50 '=' 3200 nM
P04350 BXGT006193 Tubulin beta-4A chain reviewed Cellular structure TUBB4A IC50 '=' 3200 nM
Q71U36 BXGT016705 Tubulin alpha-1A chain reviewed Cellular structure TUBA1A IC50 '=' 3200 nM
Q13509 BXGT013366 Tubulin beta-3 chain reviewed Cellular structure TUBB3 IC50 '=' 3200 nM
P68366 BXGT011595 Tubulin alpha-4A chain reviewed Cellular structure TUBA4A IC50 '=' 3200 nM
P0DPH7 BXGT007527 Tubulin alpha-3C chain reviewed - TUBA3C IC50 '=' 3200 nM
Q9H4B7 BXGT020475 Tubulin beta-1 chain reviewed Cellular structure TUBB1 IC50 '=' 3200 nM
P68371 BXGT011597 Tubulin beta-4B chain reviewed Cellular structure TUBB4B IC50 '=' 3200 nM
P10635 BXGT007595 Cytochrome P450 2D6 reviewed - CYP2D6 Inhibition - - -
Q862F3 BXGT017581 Similar to alpha-tubulin isoform 1 unreviewed - T1/2 '=' 24 hr
Q862L2 BXGT017582 Similar to alpha-tubulin isoform 1 unreviewed - T1/2 '=' 24 hr
Q6B856 BXGT016212 Tubulin beta-2B chain reviewed - TUBB2B T1/2 '=' 24 hr
P08684 BXGT006812 Cytochrome P450 3A4 reviewed Enzyme CYP3A4 Inhibition - - -
Q9BUF5 BXGT020135 Tubulin beta-6 chain reviewed Cellular structure TUBB6 IC50 '=' 500 nM
Q9BVA1 BXGT020142 Tubulin beta-2B chain reviewed - TUBB2B IC50 '=' 500 nM
Q13885 BXGT013400 Tubulin beta-2A chain reviewed Cellular structure TUBB2A IC50 '=' 500 nM
Q6PEY2 BXGT016465 Tubulin alpha-3E chain reviewed Cellular structure TUBA3E IC50 '=' 500 nM
Q9BQE3 BXGT020109 Tubulin alpha-1C chain reviewed Cellular structure TUBA1C IC50 '=' 500 nM
P68363 BXGT011594 Tubulin alpha-1B chain reviewed Cellular structure TUBA1B IC50 '=' 500 nM
P07437 BXGT006624 Tubulin beta chain reviewed Cellular structure TUBB IC50 '=' 500 nM
Q3ZCM7 BXGT014551 Tubulin beta-8 chain reviewed - TUBB8 IC50 '=' 500 nM
P04350 BXGT006193 Tubulin beta-4A chain reviewed Cellular structure TUBB4A IC50 '=' 500 nM
Q71U36 BXGT016705 Tubulin alpha-1A chain reviewed Cellular structure TUBA1A IC50 '=' 500 nM
Q13509 BXGT013366 Tubulin beta-3 chain reviewed Cellular structure TUBB3 IC50 '=' 500 nM
P68366 BXGT011595 Tubulin alpha-4A chain reviewed Cellular structure TUBA4A IC50 '=' 500 nM
P0DPH7 BXGT007527 Tubulin alpha-3C chain reviewed - TUBA3C IC50 '=' 500 nM
Q9H4B7 BXGT020475 Tubulin beta-1 chain reviewed Cellular structure TUBB1 IC50 '=' 500 nM
P68371 BXGT011597 Tubulin beta-4B chain reviewed Cellular structure TUBB4B IC50 '=' 500 nM
P31645 BXGT009558 Sodium-dependent serotonin transporter reviewed Transporter SLC6A4 IC50 - - -
P08912 BXGT006840 Muscarinic acetylcholine receptor M5 reviewed G-protein coupled receptor CHRM5 Ki - - -
O70528 BXGT005068 5-hydroxytryptamine receptor 4 reviewed - HTR4 Ki - - -
P11712 BXGT007738 Cytochrome P450 2C9 reviewed - CYP2C9 AC50 '=' 3162 nM
Q9BUF5 BXGT020135 Tubulin beta-6 chain reviewed Cellular structure TUBB6 Inhibition - - -
Q9BVA1 BXGT020142 Tubulin beta-2B chain reviewed - TUBB2B Inhibition - - -
Q13885 BXGT013400 Tubulin beta-2A chain reviewed Cellular structure TUBB2A Inhibition - - -
Q6PEY2 BXGT016465 Tubulin alpha-3E chain reviewed Cellular structure TUBA3E Inhibition - - -
Q9BQE3 BXGT020109 Tubulin alpha-1C chain reviewed Cellular structure TUBA1C Inhibition - - -
P68363 BXGT011594 Tubulin alpha-1B chain reviewed Cellular structure TUBA1B Inhibition - - -
P07437 BXGT006624 Tubulin beta chain reviewed Cellular structure TUBB Inhibition - - -
Q3ZCM7 BXGT014551 Tubulin beta-8 chain reviewed - TUBB8 Inhibition - - -
P04350 BXGT006193 Tubulin beta-4A chain reviewed Cellular structure TUBB4A Inhibition - - -
Q71U36 BXGT016705 Tubulin alpha-1A chain reviewed Cellular structure TUBA1A Inhibition - - -
Q13509 BXGT013366 Tubulin beta-3 chain reviewed Cellular structure TUBB3 Inhibition - - -
P68366 BXGT011595 Tubulin alpha-4A chain reviewed Cellular structure TUBA4A Inhibition - - -
P0DPH7 BXGT007527 Tubulin alpha-3C chain reviewed - TUBA3C Inhibition - - -
Q9H4B7 BXGT020475 Tubulin beta-1 chain reviewed Cellular structure TUBB1 Inhibition - - -
P68371 BXGT011597 Tubulin beta-4B chain reviewed Cellular structure TUBB4B Inhibition - - -
Q92793 BXGT019374 CREB-binding protein reviewed - CREBBP Potency '=' 5011 nM
P08172 BXGT006737 Muscarinic acetylcholine receptor M2 reviewed G-protein coupled receptor CHRM2 Ki - - -
P20309 BXGT008562 Muscarinic acetylcholine receptor M3 reviewed G-protein coupled receptor CHRM3 Ki - - -
P41143 BXGT010223 Delta-type opioid receptor reviewed G-protein coupled receptor OPRD1 IC50 - - -
P41145 BXGT010225 Kappa-type opioid receptor reviewed G-protein coupled receptor OPRK1 Ki - - -
P00533 BXGT005575 Epidermal growth factor receptor reviewed Kinase EGFR IC50 - - -
P41595 BXGT010267 5-hydroxytryptamine receptor 2B reviewed G-protein coupled receptor HTR2B Ki - - -
P24557 BXGT008976 Thromboxane-A synthase reviewed - TBXAS1 Ki - - -
P22303 BXGT008751 Acetylcholinesterase reviewed Enzyme ACHE IC50 - - -
P15823 BXGT008160 Alpha-1B adrenergic receptor reviewed - Adra1b IC50 - - -
P18825 BXGT008426 Alpha-2C adrenergic receptor reviewed G-protein coupled receptor ADRA2C Ki - - -
P08588 BXGT006795 Beta-1 adrenergic receptor reviewed G-protein coupled receptor ADRB1 Ki - - -
P13945 BXGT007972 Beta-3 adrenergic receptor reviewed G-protein coupled receptor ADRB3 IC50 - - -
P07943 BXGT006700 Aldo-keto reductase family 1 member B1 reviewed - Akr1b1 Ki - - -
P50052 BXGT010768 Type-2 angiotensin II receptor reviewed G-protein coupled receptor AGTR2 IC50 - - -
P51679 BXGT010877 C-C chemokine receptor type 4 reviewed G-protein coupled receptor CCR4 Ki - - -
P11712 BXGT007738 Cytochrome P450 2C9 reviewed - CYP2C9 Potency '=' 3162 nM
P19793 BXGT008515 Retinoic acid receptor RXR-alpha reviewed Nuclear receptor RXRA Potency - 39 nM
P02550 BXGT005891 Tubulin alpha-1A chain reviewed - TUBA1A Inhibition '=' 3 %
P08684 BXGT006812 Cytochrome P450 3A4 reviewed Enzyme CYP3A4 Ratio IC50 '<' 2 -
P08183 BXGT006741 ATP-dependent translocase ABCB1 reviewed Transporter ABCB1 Activity - - -
P02550 BXGT005891 Tubulin alpha-1A chain reviewed - TUBA1A IC50 '=' 29300 nM
P02554 BXGT005892 Tubulin beta chain reviewed - IC50 '=' 29300 nM
P02550 BXGT005891 Tubulin alpha-1A chain reviewed - TUBA1A Ka '=' - -
P21917 BXGT008707 D(4) dopamine receptor reviewed G-protein coupled receptor DRD4 Ki - - -
P08183 BXGT006741 ATP-dependent translocase ABCB1 reviewed Transporter ABCB1 Km '=' 1330 nM
P08482 BXGT006775 Muscarinic acetylcholine receptor M1 reviewed - Chrm1 Potency '=' 891 nM
Q27957 BXGT013938 Tubulin polymerization-promoting protein reviewed - TPPP Inhibition - - -
Q862F3 BXGT017581 Similar to alpha-tubulin isoform 1 unreviewed - ITP '=' 37 %
Q862L2 BXGT017582 Similar to alpha-tubulin isoform 1 unreviewed - ITP '=' 37 %
Q6B856 BXGT016212 Tubulin beta-2B chain reviewed - TUBB2B ITP '=' 37 %
P05177 BXGT006336 Cytochrome P450 1A2 reviewed Enzyme CYP1A2 Inhibition - - -
Q6B856 BXGT016212 Tubulin beta-2B chain reviewed - TUBB2B IC50 '=' 3500 nM
P15127 BXGT008085 Insulin receptor reviewed - Insr IC50 - - -
P14780 BXGT008053 Matrix metalloproteinase-9 reviewed Enzyme MMP9 IC50 - - -
Q08209 BXGT012968 Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform reviewed - PPP3CA IC50 - - -
P28223 BXGT009239 5-hydroxytryptamine receptor 2A reviewed G-protein coupled receptor HTR2A Ki - - -
Q9BUF5 BXGT020135 Tubulin beta-6 chain reviewed Cellular structure TUBB6 Binding '=' 90 %
Q9BVA1 BXGT020142 Tubulin beta-2B chain reviewed - TUBB2B Binding '=' 90 %
Q13885 BXGT013400 Tubulin beta-2A chain reviewed Cellular structure TUBB2A Binding '=' 90 %
Q6PEY2 BXGT016465 Tubulin alpha-3E chain reviewed Cellular structure TUBA3E Binding '=' 90 %
Q9BQE3 BXGT020109 Tubulin alpha-1C chain reviewed Cellular structure TUBA1C Binding '=' 90 %
P68363 BXGT011594 Tubulin alpha-1B chain reviewed Cellular structure TUBA1B Binding '=' 90 %
P07437 BXGT006624 Tubulin beta chain reviewed Cellular structure TUBB Binding '=' 90 %
Q3ZCM7 BXGT014551 Tubulin beta-8 chain reviewed - TUBB8 Binding '=' 90 %
P04350 BXGT006193 Tubulin beta-4A chain reviewed Cellular structure TUBB4A Binding '=' 90 %
Q71U36 BXGT016705 Tubulin alpha-1A chain reviewed Cellular structure TUBA1A Binding '=' 90 %
Q13509 BXGT013366 Tubulin beta-3 chain reviewed Cellular structure TUBB3 Binding '=' 90 %
P68366 BXGT011595 Tubulin alpha-4A chain reviewed Cellular structure TUBA4A Binding '=' 90 %
P0DPH7 BXGT007527 Tubulin alpha-3C chain reviewed - TUBA3C Binding '=' 90 %
Q9H4B7 BXGT020475 Tubulin beta-1 chain reviewed Cellular structure TUBB1 Binding '=' 90 %
P68371 BXGT011597 Tubulin beta-4B chain reviewed Cellular structure TUBB4B Binding '=' 90 %
Q862F3 BXGT017581 Similar to alpha-tubulin isoform 1 unreviewed - Relative activity '=' 1 -
Q862L2 BXGT017582 Similar to alpha-tubulin isoform 1 unreviewed - Relative activity '=' 1 -
Q6B856 BXGT016212 Tubulin beta-2B chain reviewed - TUBB2B Relative activity '=' 1 -
P06795 BXGT006507 ATP-dependent translocase ABCB1 reviewed - Abcb1b IC50 '>' 50000 nM
Q96QE3 BXGT019718 ATPase family AAA domain-containing protein 5 reviewed - ATAD5 Potency - 460 nM
Q862F3 BXGT017581 Similar to alpha-tubulin isoform 1 unreviewed - IC50 '=' 1900 nM
Q862L2 BXGT017582 Similar to alpha-tubulin isoform 1 unreviewed - IC50 '=' 1900 nM
Q6B856 BXGT016212 Tubulin beta-2B chain reviewed - TUBB2B IC50 '=' 1900 nM
O75496 BXGT005132 Geminin reviewed - GMNN Potency - 58 nM
P21452 BXGT008653 Substance-K receptor reviewed G-protein coupled receptor TACR2 IC50 - - -
P02791 BXGT005965 Ferritin light chain reviewed - FTL Potency '=' 35481 nM
P03372 BXGT006059 Estrogen receptor reviewed Nuclear receptor ESR1 Potency - 4466 nM
Q862F3 BXGT017581 Similar to alpha-tubulin isoform 1 unreviewed - Inhibition '=' 100 %
Q862L2 BXGT017582 Similar to alpha-tubulin isoform 1 unreviewed - Inhibition '=' 100 %
Q6B856 BXGT016212 Tubulin beta-2B chain reviewed - TUBB2B Inhibition '=' 100 %
Q9WKE8 BXGT021921 Reverse transcriptase unreviewed - reverse IC50 - - -
P21917 BXGT008707 D(4) dopamine receptor reviewed G-protein coupled receptor DRD4 IC50 - - -
Q01959 BXGT012624 Sodium-dependent dopamine transporter reviewed Transporter SLC6A3 IC50 - - -
Q92731 BXGT019366 Estrogen receptor beta reviewed Nuclear receptor ESR2 IC50 - - -
Q9BUF5 BXGT020135 Tubulin beta-6 chain reviewed Cellular structure TUBB6 IC50 '=' 1050 nM
Q9BVA1 BXGT020142 Tubulin beta-2B chain reviewed - TUBB2B IC50 '=' 1050 nM
Q13885 BXGT013400 Tubulin beta-2A chain reviewed Cellular structure TUBB2A IC50 '=' 1050 nM
Q6PEY2 BXGT016465 Tubulin alpha-3E chain reviewed Cellular structure TUBA3E IC50 '=' 1050 nM
Q9BQE3 BXGT020109 Tubulin alpha-1C chain reviewed Cellular structure TUBA1C IC50 '=' 1050 nM
P68363 BXGT011594 Tubulin alpha-1B chain reviewed Cellular structure TUBA1B IC50 '=' 1050 nM
P07437 BXGT006624 Tubulin beta chain reviewed Cellular structure TUBB IC50 '=' 1050 nM
Q3ZCM7 BXGT014551 Tubulin beta-8 chain reviewed - TUBB8 IC50 '=' 1050 nM
P04350 BXGT006193 Tubulin beta-4A chain reviewed Cellular structure TUBB4A IC50 '=' 1050 nM
Q71U36 BXGT016705 Tubulin alpha-1A chain reviewed Cellular structure TUBA1A IC50 '=' 1050 nM
Q13509 BXGT013366 Tubulin beta-3 chain reviewed Cellular structure TUBB3 IC50 '=' 1050 nM
P68366 BXGT011595 Tubulin alpha-4A chain reviewed Cellular structure TUBA4A IC50 '=' 1050 nM
P0DPH7 BXGT007527 Tubulin alpha-3C chain reviewed - TUBA3C IC50 '=' 1050 nM
Q9H4B7 BXGT020475 Tubulin beta-1 chain reviewed Cellular structure TUBB1 IC50 '=' 1050 nM
P68371 BXGT011597 Tubulin beta-4B chain reviewed Cellular structure TUBB4B IC50 '=' 1050 nM
Q9BUF5 BXGT020135 Tubulin beta-6 chain reviewed Cellular structure TUBB6 Activity '=' 12 uM
Q9BVA1 BXGT020142 Tubulin beta-2B chain reviewed - TUBB2B Activity '=' 12 uM
Q13885 BXGT013400 Tubulin beta-2A chain reviewed Cellular structure TUBB2A Activity '=' 12 uM
Q6PEY2 BXGT016465 Tubulin alpha-3E chain reviewed Cellular structure TUBA3E Activity '=' 12 uM
Q9BQE3 BXGT020109 Tubulin alpha-1C chain reviewed Cellular structure TUBA1C Activity '=' 12 uM
P68363 BXGT011594 Tubulin alpha-1B chain reviewed Cellular structure TUBA1B Activity '=' 12 uM
P07437 BXGT006624 Tubulin beta chain reviewed Cellular structure TUBB Activity '=' 12 uM
Q3ZCM7 BXGT014551 Tubulin beta-8 chain reviewed - TUBB8 Activity '=' 12 uM
P04350 BXGT006193 Tubulin beta-4A chain reviewed Cellular structure TUBB4A Activity '=' 12 uM
Q71U36 BXGT016705 Tubulin alpha-1A chain reviewed Cellular structure TUBA1A Activity '=' 12 uM
Q13509 BXGT013366 Tubulin beta-3 chain reviewed Cellular structure TUBB3 Activity '=' 12 uM
P68366 BXGT011595 Tubulin alpha-4A chain reviewed Cellular structure TUBA4A Activity '=' 12 uM
P0DPH7 BXGT007527 Tubulin alpha-3C chain reviewed - TUBA3C Activity '=' 12 uM
Q9H4B7 BXGT020475 Tubulin beta-1 chain reviewed Cellular structure TUBB1 Activity '=' 12 uM
P68371 BXGT011597 Tubulin beta-4B chain reviewed Cellular structure TUBB4B Activity '=' 12 uM
P02550 BXGT005891 Tubulin alpha-1A chain reviewed - TUBA1A IC50 '=' 4168 nM
P02550 BXGT005891 Tubulin alpha-1A chain reviewed - TUBA1A Inhibition '=' 78 %
P02554 BXGT005892 Tubulin beta chain reviewed - Inhibition '=' 78 %
P11509 BXGT007716 Cytochrome P450 2A6 reviewed - CYP2A6 IC50 - - -
P05181 BXGT006337 Cytochrome P450 2E1 reviewed - CYP2E1 IC50 - - -
P14416 BXGT008011 D(2) dopamine receptor reviewed G-protein coupled receptor DRD2 Ki - - -
P03372 BXGT006059 Estrogen receptor reviewed Nuclear receptor ESR1 IC50 - - -
P30542 BXGT009436 Adenosine receptor A1 reviewed G-protein coupled receptor ADORA1 Ki - - -
P41597 BXGT010268 C-C chemokine receptor type 2 reviewed - CCR2 IC50 - - -
P25024 BXGT009005 C-X-C chemokine receptor type 1 reviewed G-protein coupled receptor CXCR1 IC50 - - -
P37231 BXGT009972 Peroxisome proliferator-activated receptor gamma reviewed Nuclear receptor PPARG Potency - 25 nM
Q6B856 BXGT016212 Tubulin beta-2B chain reviewed - TUBB2B Tubulin binding '=' 90 %
Q96RI1 BXGT019727 Bile acid receptor reviewed Nuclear receptor NR1H4 Potency - 31 nM
P04035 BXGT006129 3-hydroxy-3-methylglutaryl-coenzyme A reductase reviewed - HMGCR IC50 - - -
P32245 BXGT009614 Melanocortin receptor 4 reviewed G-protein coupled receptor MC4R Ki - - -
O95235 BXGT005360 Kinesin-like protein KIF20A reviewed Cellular structure KIF20A Imax - - -
P33261 BXGT009707 Cytochrome P450 2C19 reviewed - CYP2C19 Potency '=' 12589 nM
Q862F3 BXGT017581 Similar to alpha-tubulin isoform 1 unreviewed - IC50 '=' 1900 nM
Q6B856 BXGT016212 Tubulin beta-2B chain reviewed - TUBB2B IC50 '=' 1900 nM
Q6B856 BXGT016212 Tubulin beta-2B chain reviewed - TUBB2B IC50 '=' 800 nM
Q02880 BXGT012677 DNA topoisomerase 2-beta reviewed - TOP2B Activity - - -
P11388 BXGT007697 DNA topoisomerase 2-alpha reviewed - TOP2A Activity - - -
Q862F3 BXGT017581 Similar to alpha-tubulin isoform 1 unreviewed - ITP '=' 61 %
Q862L2 BXGT017582 Similar to alpha-tubulin isoform 1 unreviewed - ITP '=' 61 %
Q6B856 BXGT016212 Tubulin beta-2B chain reviewed - TUBB2B ITP '=' 61 %
Q96KQ7 BXGT019687 Histone-lysine N-methyltransferase EHMT2 reviewed Epigenetic regulator EHMT2 Potency - 10000 nM
Q862F3 BXGT017581 Similar to alpha-tubulin isoform 1 unreviewed - IC50 '=' 1700 nM
Q862L2 BXGT017582 Similar to alpha-tubulin isoform 1 unreviewed - IC50 '=' 1700 nM
Q6B856 BXGT016212 Tubulin beta-2B chain reviewed - TUBB2B IC50 '=' 1700 nM
P11473 BXGT007709 Vitamin D3 receptor reviewed Nuclear receptor VDR Potency - 79 nM
Q96RI1 BXGT019727 Bile acid receptor reviewed Nuclear receptor NR1H4 Potency - 50 nM
P11509 BXGT007716 Cytochrome P450 2A6 reviewed - CYP2A6 Ki - - -
P05181 BXGT006337 Cytochrome P450 2E1 reviewed - CYP2E1 Ki - - -
P30988 BXGT009491 Calcitonin receptor reviewed G-protein coupled receptor CALCR IC50 - - -
P23219 BXGT008837 Prostaglandin G/H synthase 1 reviewed Enzyme PTGS1 IC50 - - -
P08913 BXGT006841 Alpha-2A adrenergic receptor reviewed G-protein coupled receptor ADRA2A IC50 - - -
P18089 BXGT008379 Alpha-2B adrenergic receptor reviewed G-protein coupled receptor ADRA2B IC50 - - -
P25024 BXGT009005 C-X-C chemokine receptor type 1 reviewed G-protein coupled receptor CXCR1 Ki - - -
P25025 BXGT009006 C-X-C chemokine receptor type 2 reviewed G-protein coupled receptor CXCR2 Ki - - -
P16473 BXGT008234 Thyrotropin receptor reviewed G-protein coupled receptor TSHR Potency '=' 15848 nM
O15245 BXGT004141 Solute carrier family 22 member 1 reviewed Transporter SLC22A1 Inhibition '=' 31 %
A6XA80 BXGT001522 Leukotriene C4 synthase reviewed - LTC4S Ki - - -
P41968 BXGT010275 Melanocortin receptor 3 reviewed G-protein coupled receptor MC3R IC50 - - -
P11229 BXGT007676 Muscarinic acetylcholine receptor M1 reviewed G-protein coupled receptor CHRM1 IC50 - - -
P41595 BXGT010267 5-hydroxytryptamine receptor 2B reviewed G-protein coupled receptor HTR2B IC50 - - -
P21452 BXGT008653 Substance-K receptor reviewed G-protein coupled receptor TACR2 Ki - - -
P37288 BXGT009977 Vasopressin V1a receptor reviewed G-protein coupled receptor AVPR1A Ki - - -
Q9WKE8 BXGT021921 Reverse transcriptase unreviewed - reverse IC50 '>' 200 ug.mL-1
P04150 BXGT006154 Glucocorticoid receptor reviewed Nuclear receptor NR3C1 Potency - 4466 nM
P08684 BXGT006812 Cytochrome P450 3A4 reviewed Enzyme CYP3A4 Potency '=' 2511 nM
P20781 BXGT008598 Glycine receptor subunit beta reviewed - Glrb Ki - - -
P07727 BXGT006662 Glycine receptor subunit alpha-1 reviewed - Glra1 Ki - - -
P24524 BXGT008974 Glycine receptor subunit alpha-3 reviewed - Glra3 Ki - - -
P22771 BXGT008806 Glycine receptor subunit alpha-2 reviewed - Glra2 Ki - - -
P25929 BXGT009078 Neuropeptide Y receptor type 1 reviewed G-protein coupled receptor NPY1R Ki - - -
P35372 BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 Ki - - -
P25105 BXGT009021 Platelet-activating factor receptor reviewed G-protein coupled receptor PTAFR IC50 - - -
P08311 BXGT006762 Cathepsin G reviewed Enzyme CTSG Ki - - -
P28482 BXGT009263 Mitogen-activated protein kinase 1 reviewed Kinase MAPK1 IC50 - - -
Q08209 BXGT012968 Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform reviewed - PPP3CA Ki - - -
P16473 BXGT008234 Thyrotropin receptor reviewed G-protein coupled receptor TSHR Potency '=' 1995 nM
P02550 BXGT005891 Tubulin alpha-1A chain reviewed - TUBA1A IC50 '=' 1260 nM
P02554 BXGT005892 Tubulin beta chain reviewed - IC50 '=' 1260 nM
P02550 BXGT005891 Tubulin alpha-1A chain reviewed - TUBA1A Ki '=' 2500 nM
Q862F3 BXGT017581 Similar to alpha-tubulin isoform 1 unreviewed - IC50 '=' 11200 nM
Q862L2 BXGT017582 Similar to alpha-tubulin isoform 1 unreviewed - IC50 '=' 11200 nM
Q6B856 BXGT016212 Tubulin beta-2B chain reviewed - TUBB2B IC50 '=' 11200 nM
Q9BUF5 BXGT020135 Tubulin beta-6 chain reviewed Cellular structure TUBB6 IC50 '=' 1500 nM
Q9BVA1 BXGT020142 Tubulin beta-2B chain reviewed - TUBB2B IC50 '=' 1500 nM
Q13885 BXGT013400 Tubulin beta-2A chain reviewed Cellular structure TUBB2A IC50 '=' 1500 nM
Q6PEY2 BXGT016465 Tubulin alpha-3E chain reviewed Cellular structure TUBA3E IC50 '=' 1500 nM
Q9BQE3 BXGT020109 Tubulin alpha-1C chain reviewed Cellular structure TUBA1C IC50 '=' 1500 nM
P68363 BXGT011594 Tubulin alpha-1B chain reviewed Cellular structure TUBA1B IC50 '=' 1500 nM
P07437 BXGT006624 Tubulin beta chain reviewed Cellular structure TUBB IC50 '=' 1500 nM
Q3ZCM7 BXGT014551 Tubulin beta-8 chain reviewed - TUBB8 IC50 '=' 1500 nM
P04350 BXGT006193 Tubulin beta-4A chain reviewed Cellular structure TUBB4A IC50 '=' 1500 nM
Q71U36 BXGT016705 Tubulin alpha-1A chain reviewed Cellular structure TUBA1A IC50 '=' 1500 nM
Q13509 BXGT013366 Tubulin beta-3 chain reviewed Cellular structure TUBB3 IC50 '=' 1500 nM
P68366 BXGT011595 Tubulin alpha-4A chain reviewed Cellular structure TUBA4A IC50 '=' 1500 nM
P0DPH7 BXGT007527 Tubulin alpha-3C chain reviewed - TUBA3C IC50 '=' 1500 nM
Q9H4B7 BXGT020475 Tubulin beta-1 chain reviewed Cellular structure TUBB1 IC50 '=' 1500 nM
P68371 BXGT011597 Tubulin beta-4B chain reviewed Cellular structure TUBB4B IC50 '=' 1500 nM
Q9BUF5 BXGT020135 Tubulin beta-6 chain reviewed Cellular structure TUBB6 IC50 '=' 1400 nM
Q9BVA1 BXGT020142 Tubulin beta-2B chain reviewed - TUBB2B IC50 '=' 1400 nM
Q13885 BXGT013400 Tubulin beta-2A chain reviewed Cellular structure TUBB2A IC50 '=' 1400 nM
Q6PEY2 BXGT016465 Tubulin alpha-3E chain reviewed Cellular structure TUBA3E IC50 '=' 1400 nM
Q9BQE3 BXGT020109 Tubulin alpha-1C chain reviewed Cellular structure TUBA1C IC50 '=' 1400 nM
P68363 BXGT011594 Tubulin alpha-1B chain reviewed Cellular structure TUBA1B IC50 '=' 1400 nM
P07437 BXGT006624 Tubulin beta chain reviewed Cellular structure TUBB IC50 '=' 1400 nM
Q3ZCM7 BXGT014551 Tubulin beta-8 chain reviewed - TUBB8 IC50 '=' 1400 nM
P04350 BXGT006193 Tubulin beta-4A chain reviewed Cellular structure TUBB4A IC50 '=' 1400 nM
Q71U36 BXGT016705 Tubulin alpha-1A chain reviewed Cellular structure TUBA1A IC50 '=' 1400 nM
Q13509 BXGT013366 Tubulin beta-3 chain reviewed Cellular structure TUBB3 IC50 '=' 1400 nM
P68366 BXGT011595 Tubulin alpha-4A chain reviewed Cellular structure TUBA4A IC50 '=' 1400 nM
P0DPH7 BXGT007527 Tubulin alpha-3C chain reviewed - TUBA3C IC50 '=' 1400 nM
Q9H4B7 BXGT020475 Tubulin beta-1 chain reviewed Cellular structure TUBB1 IC50 '=' 1400 nM
P68371 BXGT011597 Tubulin beta-4B chain reviewed Cellular structure TUBB4B IC50 '=' 1400 nM
P08684 BXGT006812 Cytochrome P450 3A4 reviewed Enzyme CYP3A4 IC50 '>' 50000 nM
Q862F3 BXGT017581 Similar to alpha-tubulin isoform 1 unreviewed - Inhibition '=' 26 %
Q862L2 BXGT017582 Similar to alpha-tubulin isoform 1 unreviewed - Inhibition '=' 26 %
Q6B856 BXGT016212 Tubulin beta-2B chain reviewed - TUBB2B Inhibition '=' 26 %
Q6B856 BXGT016212 Tubulin beta-2B chain reviewed - TUBB2B IC50 '=' 2400 nM
P51151 BXGT010837 Ras-related protein Rab-9A reviewed - RAB9A Potency '=' 580478 nM
Q9BUF5 BXGT020135 Tubulin beta-6 chain reviewed Cellular structure TUBB6 Activity '=' 1 uM
Q9BVA1 BXGT020142 Tubulin beta-2B chain reviewed - TUBB2B Activity '=' 1 uM
Q13885 BXGT013400 Tubulin beta-2A chain reviewed Cellular structure TUBB2A Activity '=' 1 uM
Q6PEY2 BXGT016465 Tubulin alpha-3E chain reviewed Cellular structure TUBA3E Activity '=' 1 uM
Q9BQE3 BXGT020109 Tubulin alpha-1C chain reviewed Cellular structure TUBA1C Activity '=' 1 uM
P68363 BXGT011594 Tubulin alpha-1B chain reviewed Cellular structure TUBA1B Activity '=' 1 uM
P07437 BXGT006624 Tubulin beta chain reviewed Cellular structure TUBB Activity '=' 1 uM
Q3ZCM7 BXGT014551 Tubulin beta-8 chain reviewed - TUBB8 Activity '=' 1 uM
P04350 BXGT006193 Tubulin beta-4A chain reviewed Cellular structure TUBB4A Activity '=' 1 uM
Q71U36 BXGT016705 Tubulin alpha-1A chain reviewed Cellular structure TUBA1A Activity '=' 1 uM
Q13509 BXGT013366 Tubulin beta-3 chain reviewed Cellular structure TUBB3 Activity '=' 1 uM
P68366 BXGT011595 Tubulin alpha-4A chain reviewed Cellular structure TUBA4A Activity '=' 1 uM
P0DPH7 BXGT007527 Tubulin alpha-3C chain reviewed - TUBA3C Activity '=' 1 uM
Q9H4B7 BXGT020475 Tubulin beta-1 chain reviewed Cellular structure TUBB1 Activity '=' 1 uM
P68371 BXGT011597 Tubulin beta-4B chain reviewed Cellular structure TUBB4B Activity '=' 1 uM
O35379 BXGT004525 Multidrug resistance-associated protein 1 reviewed - Abcc1 Activity - - -
P02550 BXGT005891 Tubulin alpha-1A chain reviewed - TUBA1A Ki '=' 5750 nM
P02554 BXGT005892 Tubulin beta chain reviewed - Ki '=' 5750 nM
O75496 BXGT005132 Geminin reviewed - GMNN Potency - 30 nM
P25103 BXGT009020 Substance-P receptor reviewed G-protein coupled receptor TACR1 IC50 - - -
P32241 BXGT009613 Vasoactive intestinal polypeptide receptor 1 reviewed G-protein coupled receptor VIPR1 IC50 - - -
Q03181 BXGT012701 Peroxisome proliferator-activated receptor delta reviewed Nuclear receptor PPARD Potency - 31 nM
Q64133 BXGT016109 Amine oxidase [flavin-containing] A reviewed - Maoa Activity - - -
P19793 BXGT008515 Retinoic acid receptor RXR-alpha reviewed Nuclear receptor RXRA Potency - 25 nM
P08183 BXGT006741 ATP-dependent translocase ABCB1 reviewed Transporter ABCB1 Papp '=' 17 nm/s
P02550 BXGT005891 Tubulin alpha-1A chain reviewed - TUBA1A Activity '=' 72 %
P02554 BXGT005892 Tubulin beta chain reviewed - Activity '=' 72 %
P02550 BXGT005891 Tubulin alpha-1A chain reviewed - TUBA1A Activity - - -
P02554 BXGT005892 Tubulin beta chain reviewed - Activity - - -
P08246 BXGT006756 Neutrophil elastase reviewed Enzyme ELANE Ki - - -
Q99720 BXGT019955 Sigma non-opioid intracellular receptor 1 reviewed - SIGMAR1 Ki - - -
P25103 BXGT009020 Substance-P receptor reviewed G-protein coupled receptor TACR1 Ki - - -
P32241 BXGT009613 Vasoactive intestinal polypeptide receptor 1 reviewed G-protein coupled receptor VIPR1 Ki - - -
P51449 BXGT010846 Nuclear receptor ROR-gamma reviewed Nuclear receptor RORC Potency - 118 nM
P28482 BXGT009263 Mitogen-activated protein kinase 1 reviewed Kinase MAPK1 Ki - - -
P08684 BXGT006812 Cytochrome P450 3A4 reviewed Enzyme CYP3A4 Log 1/Km '=' -3 -
Q9BUF5 BXGT020135 Tubulin beta-6 chain reviewed Cellular structure TUBB6 Tubulin binding '=' 90 %
Q9BVA1 BXGT020142 Tubulin beta-2B chain reviewed - TUBB2B Tubulin binding '=' 90 %
Q13885 BXGT013400 Tubulin beta-2A chain reviewed Cellular structure TUBB2A Tubulin binding '=' 90 %
Q6PEY2 BXGT016465 Tubulin alpha-3E chain reviewed Cellular structure TUBA3E Tubulin binding '=' 90 %
Q9BQE3 BXGT020109 Tubulin alpha-1C chain reviewed Cellular structure TUBA1C Tubulin binding '=' 90 %
P68363 BXGT011594 Tubulin alpha-1B chain reviewed Cellular structure TUBA1B Tubulin binding '=' 90 %
P07437 BXGT006624 Tubulin beta chain reviewed Cellular structure TUBB Tubulin binding '=' 90 %
Q3ZCM7 BXGT014551 Tubulin beta-8 chain reviewed - TUBB8 Tubulin binding '=' 90 %
P04350 BXGT006193 Tubulin beta-4A chain reviewed Cellular structure TUBB4A Tubulin binding '=' 90 %
Q71U36 BXGT016705 Tubulin alpha-1A chain reviewed Cellular structure TUBA1A Tubulin binding '=' 90 %
Q13509 BXGT013366 Tubulin beta-3 chain reviewed Cellular structure TUBB3 Tubulin binding '=' 90 %
P68366 BXGT011595 Tubulin alpha-4A chain reviewed Cellular structure TUBA4A Tubulin binding '=' 90 %
P0DPH7 BXGT007527 Tubulin alpha-3C chain reviewed - TUBA3C Tubulin binding '=' 90 %
Q9H4B7 BXGT020475 Tubulin beta-1 chain reviewed Cellular structure TUBB1 Tubulin binding '=' 90 %
P68371 BXGT011597 Tubulin beta-4B chain reviewed Cellular structure TUBB4B Tubulin binding '=' 90 %
Q03181 BXGT012701 Peroxisome proliferator-activated receptor delta reviewed Nuclear receptor PPARD Potency - 7943 nM
Q03181 BXGT012701 Peroxisome proliferator-activated receptor delta reviewed Nuclear receptor PPARD Potency - 17 nM
P08183 BXGT006741 ATP-dependent translocase ABCB1 reviewed Transporter ABCB1 Inhibition '=' 8 %
Q02880 BXGT012677 DNA topoisomerase 2-beta reviewed - TOP2B IC50 - - -
P11388 BXGT007697 DNA topoisomerase 2-alpha reviewed - TOP2A IC50 - - -
P37231 BXGT009972 Peroxisome proliferator-activated receptor gamma reviewed Nuclear receptor PPARG Potency - 10 nM
P08575 BXGT006793 Receptor-type tyrosine-protein phosphatase C reviewed Enzyme PTPRC IC50 - - -
P35354 BXGT009816 Prostaglandin G/H synthase 2 reviewed Enzyme PTGS2 IC50 - - -
P22303 BXGT008751 Acetylcholinesterase reviewed Enzyme ACHE Ki - - -
P23975 BXGT008935 Sodium-dependent noradrenaline transporter reviewed Transporter SLC6A2 IC50 - - -
P08173 BXGT006738 Muscarinic acetylcholine receptor M4 reviewed G-protein coupled receptor CHRM4 Ki - - -
P33032 BXGT009689 Melanocortin receptor 5 reviewed G-protein coupled receptor MC5R IC50 - - -
P29477 BXGT009355 Nitric oxide synthase, inducible reviewed - Nos2 Ki - - -
Q9BUF5 BXGT020135 Tubulin beta-6 chain reviewed Cellular structure TUBB6 IC50 '=' 3300 nM
Q9BVA1 BXGT020142 Tubulin beta-2B chain reviewed - TUBB2B IC50 '=' 3300 nM
Q13885 BXGT013400 Tubulin beta-2A chain reviewed Cellular structure TUBB2A IC50 '=' 3300 nM
Q6PEY2 BXGT016465 Tubulin alpha-3E chain reviewed Cellular structure TUBA3E IC50 '=' 3300 nM
Q9BQE3 BXGT020109 Tubulin alpha-1C chain reviewed Cellular structure TUBA1C IC50 '=' 3300 nM
P68363 BXGT011594 Tubulin alpha-1B chain reviewed Cellular structure TUBA1B IC50 '=' 3300 nM
P07437 BXGT006624 Tubulin beta chain reviewed Cellular structure TUBB IC50 '=' 3300 nM
Q3ZCM7 BXGT014551 Tubulin beta-8 chain reviewed - TUBB8 IC50 '=' 3300 nM
P04350 BXGT006193 Tubulin beta-4A chain reviewed Cellular structure TUBB4A IC50 '=' 3300 nM
Q71U36 BXGT016705 Tubulin alpha-1A chain reviewed Cellular structure TUBA1A IC50 '=' 3300 nM
Q13509 BXGT013366 Tubulin beta-3 chain reviewed Cellular structure TUBB3 IC50 '=' 3300 nM
P68366 BXGT011595 Tubulin alpha-4A chain reviewed Cellular structure TUBA4A IC50 '=' 3300 nM
P0DPH7 BXGT007527 Tubulin alpha-3C chain reviewed - TUBA3C IC50 '=' 3300 nM
Q9H4B7 BXGT020475 Tubulin beta-1 chain reviewed Cellular structure TUBB1 IC50 '=' 3300 nM
P68371 BXGT011597 Tubulin beta-4B chain reviewed Cellular structure TUBB4B IC50 '=' 3300 nM
P04150 BXGT006154 Glucocorticoid receptor reviewed Nuclear receptor NR3C1 IC50 - - -
P08912 BXGT006840 Muscarinic acetylcholine receptor M5 reviewed G-protein coupled receptor CHRM5 IC50 - - -
P49146 BXGT010681 Neuropeptide Y receptor type 2 reviewed G-protein coupled receptor NPY2R IC50 - - -
P49146 BXGT010681 Neuropeptide Y receptor type 2 reviewed G-protein coupled receptor NPY2R Ki - - -
P29476 BXGT009354 Nitric oxide synthase, brain reviewed - Nos1 IC50 - - -
Q690N0 BXGT016199 Progesterone receptor unreviewed - PGR IC50 - - -
P12822 BXGT007850 Angiotensin-converting enzyme reviewed - ACE IC50 - - -
Q16539 BXGT013634 Mitogen-activated protein kinase 14 reviewed Kinase MAPK14 IC50 - - -
Q99720 BXGT019955 Sigma non-opioid intracellular receptor 1 reviewed - SIGMAR1 IC50 - - -
P17948 BXGT008358 Vascular endothelial growth factor receptor 1 reviewed Kinase FLT1 Ki - - -
P21397 BXGT008644 Amine oxidase [flavin-containing] A reviewed - MAOA IC50 - - -
P41143 BXGT010223 Delta-type opioid receptor reviewed G-protein coupled receptor OPRD1 Ki - - -
P08311 BXGT006762 Cathepsin G reviewed Enzyme CTSG IC50 - - -
P17948 BXGT008358 Vascular endothelial growth factor receptor 1 reviewed Kinase FLT1 IC50 - - -
P04150 BXGT006154 Glucocorticoid receptor reviewed Nuclear receptor NR3C1 Ki - - -
P06241 BXGT006429 Tyrosine-protein kinase Fyn reviewed Kinase FYN IC50 - - -
Q9BUF5 BXGT020135 Tubulin beta-6 chain reviewed Cellular structure TUBB6 Activity '=' 40 %
Q9BVA1 BXGT020142 Tubulin beta-2B chain reviewed - TUBB2B Activity '=' 40 %
Q13885 BXGT013400 Tubulin beta-2A chain reviewed Cellular structure TUBB2A Activity '=' 40 %
Q6PEY2 BXGT016465 Tubulin alpha-3E chain reviewed Cellular structure TUBA3E Activity '=' 40 %
Q9BQE3 BXGT020109 Tubulin alpha-1C chain reviewed Cellular structure TUBA1C Activity '=' 40 %
P68363 BXGT011594 Tubulin alpha-1B chain reviewed Cellular structure TUBA1B Activity '=' 40 %
P07437 BXGT006624 Tubulin beta chain reviewed Cellular structure TUBB Activity '=' 40 %
Q3ZCM7 BXGT014551 Tubulin beta-8 chain reviewed - TUBB8 Activity '=' 40 %
P04350 BXGT006193 Tubulin beta-4A chain reviewed Cellular structure TUBB4A Activity '=' 40 %
Q71U36 BXGT016705 Tubulin alpha-1A chain reviewed Cellular structure TUBA1A Activity '=' 40 %
Q13509 BXGT013366 Tubulin beta-3 chain reviewed Cellular structure TUBB3 Activity '=' 40 %
P68366 BXGT011595 Tubulin alpha-4A chain reviewed Cellular structure TUBA4A Activity '=' 40 %
P0DPH7 BXGT007527 Tubulin alpha-3C chain reviewed - TUBA3C Activity '=' 40 %
Q9H4B7 BXGT020475 Tubulin beta-1 chain reviewed Cellular structure TUBB1 Activity '=' 40 %
P68371 BXGT011597 Tubulin beta-4B chain reviewed Cellular structure TUBB4B Activity '=' 40 %
Q9BUF5 BXGT020135 Tubulin beta-6 chain reviewed Cellular structure TUBB6 Inhibition '=' 82 %
Q9BVA1 BXGT020142 Tubulin beta-2B chain reviewed - TUBB2B Inhibition '=' 82 %
Q13885 BXGT013400 Tubulin beta-2A chain reviewed Cellular structure TUBB2A Inhibition '=' 82 %
Q6PEY2 BXGT016465 Tubulin alpha-3E chain reviewed Cellular structure TUBA3E Inhibition '=' 82 %
Q9BQE3 BXGT020109 Tubulin alpha-1C chain reviewed Cellular structure TUBA1C Inhibition '=' 82 %
P68363 BXGT011594 Tubulin alpha-1B chain reviewed Cellular structure TUBA1B Inhibition '=' 82 %
P07437 BXGT006624 Tubulin beta chain reviewed Cellular structure TUBB Inhibition '=' 82 %
Q3ZCM7 BXGT014551 Tubulin beta-8 chain reviewed - TUBB8 Inhibition '=' 82 %
P04350 BXGT006193 Tubulin beta-4A chain reviewed Cellular structure TUBB4A Inhibition '=' 82 %
Q71U36 BXGT016705 Tubulin alpha-1A chain reviewed Cellular structure TUBA1A Inhibition '=' 82 %
Q13509 BXGT013366 Tubulin beta-3 chain reviewed Cellular structure TUBB3 Inhibition '=' 82 %
P68366 BXGT011595 Tubulin alpha-4A chain reviewed Cellular structure TUBA4A Inhibition '=' 82 %
P0DPH7 BXGT007527 Tubulin alpha-3C chain reviewed - TUBA3C Inhibition '=' 82 %
Q9H4B7 BXGT020475 Tubulin beta-1 chain reviewed Cellular structure TUBB1 Inhibition '=' 82 %
P68371 BXGT011597 Tubulin beta-4B chain reviewed Cellular structure TUBB4B Inhibition '=' 82 %
Q9BUF5 BXGT020135 Tubulin beta-6 chain reviewed Cellular structure TUBB6 Activity '=' 11 um/min
Q9BVA1 BXGT020142 Tubulin beta-2B chain reviewed - TUBB2B Activity '=' 11 um/min
Q13885 BXGT013400 Tubulin beta-2A chain reviewed Cellular structure TUBB2A Activity '=' 11 um/min
Q6PEY2 BXGT016465 Tubulin alpha-3E chain reviewed Cellular structure TUBA3E Activity '=' 11 um/min
Q9BQE3 BXGT020109 Tubulin alpha-1C chain reviewed Cellular structure TUBA1C Activity '=' 11 um/min
P68363 BXGT011594 Tubulin alpha-1B chain reviewed Cellular structure TUBA1B Activity '=' 11 um/min
P07437 BXGT006624 Tubulin beta chain reviewed Cellular structure TUBB Activity '=' 11 um/min
Q3ZCM7 BXGT014551 Tubulin beta-8 chain reviewed - TUBB8 Activity '=' 11 um/min
P04350 BXGT006193 Tubulin beta-4A chain reviewed Cellular structure TUBB4A Activity '=' 11 um/min
Q71U36 BXGT016705 Tubulin alpha-1A chain reviewed Cellular structure TUBA1A Activity '=' 11 um/min
Q13509 BXGT013366 Tubulin beta-3 chain reviewed Cellular structure TUBB3 Activity '=' 11 um/min
P68366 BXGT011595 Tubulin alpha-4A chain reviewed Cellular structure TUBA4A Activity '=' 11 um/min
P0DPH7 BXGT007527 Tubulin alpha-3C chain reviewed - TUBA3C Activity '=' 11 um/min
Q9H4B7 BXGT020475 Tubulin beta-1 chain reviewed Cellular structure TUBB1 Activity '=' 11 um/min
P68371 BXGT011597 Tubulin beta-4B chain reviewed Cellular structure TUBB4B Activity '=' 11 um/min
P02550 BXGT005891 Tubulin alpha-1A chain reviewed - TUBA1A Kd '=' 3700 nM
P02554 BXGT005892 Tubulin beta chain reviewed - Kd '=' 3700 nM
Q9BUF5 BXGT020135 Tubulin beta-6 chain reviewed Cellular structure TUBB6 Inhibition '=' 86 %
Q9BVA1 BXGT020142 Tubulin beta-2B chain reviewed - TUBB2B Inhibition '=' 86 %
Q13885 BXGT013400 Tubulin beta-2A chain reviewed Cellular structure TUBB2A Inhibition '=' 86 %
Q6PEY2 BXGT016465 Tubulin alpha-3E chain reviewed Cellular structure TUBA3E Inhibition '=' 86 %
Q9BQE3 BXGT020109 Tubulin alpha-1C chain reviewed Cellular structure TUBA1C Inhibition '=' 86 %
P68363 BXGT011594 Tubulin alpha-1B chain reviewed Cellular structure TUBA1B Inhibition '=' 86 %
P07437 BXGT006624 Tubulin beta chain reviewed Cellular structure TUBB Inhibition '=' 86 %
Q3ZCM7 BXGT014551 Tubulin beta-8 chain reviewed - TUBB8 Inhibition '=' 86 %
P04350 BXGT006193 Tubulin beta-4A chain reviewed Cellular structure TUBB4A Inhibition '=' 86 %
Q71U36 BXGT016705 Tubulin alpha-1A chain reviewed Cellular structure TUBA1A Inhibition '=' 86 %
Q13509 BXGT013366 Tubulin beta-3 chain reviewed Cellular structure TUBB3 Inhibition '=' 86 %
P68366 BXGT011595 Tubulin alpha-4A chain reviewed Cellular structure TUBA4A Inhibition '=' 86 %
P0DPH7 BXGT007527 Tubulin alpha-3C chain reviewed - TUBA3C Inhibition '=' 86 %
Q9H4B7 BXGT020475 Tubulin beta-1 chain reviewed Cellular structure TUBB1 Inhibition '=' 86 %
P68371 BXGT011597 Tubulin beta-4B chain reviewed Cellular structure TUBB4B Inhibition '=' 86 %
Q27957 BXGT013938 Tubulin polymerization-promoting protein reviewed - TPPP EC50 '=' 750 nM
P68370 BXGT011596 Tubulin alpha-1A chain reviewed - Tuba1a Inhibition '=' 93 %
P12822 BXGT007850 Angiotensin-converting enzyme reviewed - ACE Ki - - -
P14780 BXGT008053 Matrix metalloproteinase-9 reviewed Enzyme MMP9 Ki - - -
P03956 BXGT006120 Interstitial collagenase reviewed Enzyme MMP1 IC50 - - -
P32238 BXGT009611 Cholecystokinin receptor type A reviewed G-protein coupled receptor CCKAR Ki - - -
P25100 BXGT009017 Alpha-1D adrenergic receptor reviewed G-protein coupled receptor ADRA1D IC50 - - -
P29274 BXGT009327 Adenosine receptor A2a reviewed G-protein coupled receptor ADORA2A IC50 - - -
P43140 BXGT010360 Alpha-1A adrenergic receptor reviewed - Adra1a Ki - - -
P15823 BXGT008160 Alpha-1B adrenergic receptor reviewed - Adra1b Ki - - -
P30988 BXGT009491 Calcitonin receptor reviewed G-protein coupled receptor CALCR Ki - - -
P51679 BXGT010877 C-C chemokine receptor type 4 reviewed G-protein coupled receptor CCR4 IC50 - - -
P05177 BXGT006336 Cytochrome P450 1A2 reviewed Enzyme CYP1A2 Ki - - -
P10635 BXGT007595 Cytochrome P450 2D6 reviewed - CYP2D6 Ki - - -
P25101 BXGT009018 Endothelin-1 receptor reviewed G-protein coupled receptor EDNRA IC50 - - -
P20781 BXGT008598 Glycine receptor subunit beta reviewed - Glrb IC50 - - -
P07727 BXGT006662 Glycine receptor subunit alpha-1 reviewed - Glra1 IC50 - - -
P24524 BXGT008974 Glycine receptor subunit alpha-3 reviewed - Glra3 IC50 - - -
P22771 BXGT008806 Glycine receptor subunit alpha-2 reviewed - Glra2 IC50 - - -
P41145 BXGT010225 Kappa-type opioid receptor reviewed G-protein coupled receptor OPRK1 IC50 - - -
Q12809 BXGT013267 Potassium voltage-gated channel subfamily H member 2 reviewed Ion channel KCNH2 IC50 - - -
Q9R1A7 BXGT021413 Nuclear receptor subfamily 1 group I member 2 reviewed - Nr1i2 Potency - 15848 nM
P10828 BXGT007624 Thyroid hormone receptor beta reviewed Nuclear receptor THRB Potency - 44 nM
O89049 BXGT005293 Thioredoxin reductase 1, cytoplasmic reviewed - Txnrd1 Potency - 843 nM
P15917 BXGT008169 Lethal factor reviewed - lef Potency '=' 31622 nM
P07437 BXGT006624 Tubulin beta chain reviewed Cellular structure TUBB Inhibition '=' 82 %
P28335 BXGT009255 5-hydroxytryptamine receptor 2C reviewed G-protein coupled receptor HTR2C IC50 - - -
P10275 BXGT007552 Androgen receptor reviewed Nuclear receptor AR Potency - 35 nM
P02550 BXGT005891 Tubulin alpha-1A chain reviewed - TUBA1A IC50 '=' 800 nM
Q9NUW8 BXGT021219 Tyrosyl-DNA phosphodiesterase 1 reviewed Enzyme TDP1 Potency - 47 nM
P02550 BXGT005891 Tubulin alpha-1A chain reviewed - TUBA1A IC50 '=' 1500 nM
Q9R1A7 BXGT021413 Nuclear receptor subfamily 1 group I member 2 reviewed - Nr1i2 Potency - 1584 nM
P14416 BXGT008011 D(2) dopamine receptor reviewed G-protein coupled receptor DRD2 IC50 - - -
P08183 BXGT006741 ATP-dependent translocase ABCB1 reviewed Transporter ABCB1 Papp '=' 202 nm/s
Q862F3 BXGT017581 Similar to alpha-tubulin isoform 1 unreviewed - Inhibition - - -
Q862L2 BXGT017582 Similar to alpha-tubulin isoform 1 unreviewed - Inhibition - - -
Q6B856 BXGT016212 Tubulin beta-2B chain reviewed - TUBB2B Inhibition - - -
Q96QE3 BXGT019718 ATPase family AAA domain-containing protein 5 reviewed - ATAD5 Potency - 23099 nM
Q862F3 BXGT017581 Similar to alpha-tubulin isoform 1 unreviewed - ITP '=' 70 %
Q862L2 BXGT017582 Similar to alpha-tubulin isoform 1 unreviewed - ITP '=' 70 %
Q6B856 BXGT016212 Tubulin beta-2B chain reviewed - TUBB2B ITP '=' 70 %
P04062 BXGT006140 Lysosomal acid glucosylceramidase reviewed - GBA Potency - 39810 nM
P04626 BXGT006238 Receptor tyrosine-protein kinase erbB-2 reviewed Kinase ERBB2 Ki - - -
Q6B856 BXGT016212 Tubulin beta-2B chain reviewed - TUBB2B GTPase Activity '=' 10 -
Q9BUF5 BXGT020135 Tubulin beta-6 chain reviewed Cellular structure TUBB6 IC50 '=' 1900 nM
Q9BVA1 BXGT020142 Tubulin beta-2B chain reviewed - TUBB2B IC50 '=' 1900 nM
Q13885 BXGT013400 Tubulin beta-2A chain reviewed Cellular structure TUBB2A IC50 '=' 1900 nM
Q6PEY2 BXGT016465 Tubulin alpha-3E chain reviewed Cellular structure TUBA3E IC50 '=' 1900 nM
Q9BQE3 BXGT020109 Tubulin alpha-1C chain reviewed Cellular structure TUBA1C IC50 '=' 1900 nM
P68363 BXGT011594 Tubulin alpha-1B chain reviewed Cellular structure TUBA1B IC50 '=' 1900 nM
P07437 BXGT006624 Tubulin beta chain reviewed Cellular structure TUBB IC50 '=' 1900 nM
Q3ZCM7 BXGT014551 Tubulin beta-8 chain reviewed - TUBB8 IC50 '=' 1900 nM
P04350 BXGT006193 Tubulin beta-4A chain reviewed Cellular structure TUBB4A IC50 '=' 1900 nM
Q71U36 BXGT016705 Tubulin alpha-1A chain reviewed Cellular structure TUBA1A IC50 '=' 1900 nM
Q13509 BXGT013366 Tubulin beta-3 chain reviewed Cellular structure TUBB3 IC50 '=' 1900 nM
P68366 BXGT011595 Tubulin alpha-4A chain reviewed Cellular structure TUBA4A IC50 '=' 1900 nM
P0DPH7 BXGT007527 Tubulin alpha-3C chain reviewed - TUBA3C IC50 '=' 1900 nM
Q9H4B7 BXGT020475 Tubulin beta-1 chain reviewed Cellular structure TUBB1 IC50 '=' 1900 nM
P68371 BXGT011597 Tubulin beta-4B chain reviewed Cellular structure TUBB4B IC50 '=' 1900 nM
P08183 BXGT006741 ATP-dependent translocase ABCB1 reviewed Transporter ABCB1 Ratio_Papp '=' 11 -
P43140 BXGT010360 Alpha-1A adrenergic receptor reviewed - Adra1a IC50 - - -
P30411 BXGT009424 B2 bradykinin receptor reviewed G-protein coupled receptor BDKRB2 Ki - - -
Q9BUF5 BXGT020135 Tubulin beta-6 chain reviewed Cellular structure TUBB6 IC50 - - -
Q9BVA1 BXGT020142 Tubulin beta-2B chain reviewed - TUBB2B IC50 - - -
Q13885 BXGT013400 Tubulin beta-2A chain reviewed Cellular structure TUBB2A IC50 - - -
Q6PEY2 BXGT016465 Tubulin alpha-3E chain reviewed Cellular structure TUBA3E IC50 - - -
Q9BQE3 BXGT020109 Tubulin alpha-1C chain reviewed Cellular structure TUBA1C IC50 - - -
P68363 BXGT011594 Tubulin alpha-1B chain reviewed Cellular structure TUBA1B IC50 - - -
P07437 BXGT006624 Tubulin beta chain reviewed Cellular structure TUBB IC50 - - -
Q3ZCM7 BXGT014551 Tubulin beta-8 chain reviewed - TUBB8 IC50 - - -
P04350 BXGT006193 Tubulin beta-4A chain reviewed Cellular structure TUBB4A IC50 - - -
Q71U36 BXGT016705 Tubulin alpha-1A chain reviewed Cellular structure TUBA1A IC50 - - -
Q13509 BXGT013366 Tubulin beta-3 chain reviewed Cellular structure TUBB3 IC50 - - -
P68366 BXGT011595 Tubulin alpha-4A chain reviewed Cellular structure TUBA4A IC50 - - -
P0DPH7 BXGT007527 Tubulin alpha-3C chain reviewed - TUBA3C IC50 - - -
Q9H4B7 BXGT020475 Tubulin beta-1 chain reviewed Cellular structure TUBB1 IC50 - - -
P68371 BXGT011597 Tubulin beta-4B chain reviewed Cellular structure TUBB4B IC50 - - -
Q9BUF5 BXGT020135 Tubulin beta-6 chain reviewed Cellular structure TUBB6 Ki '=' 1600 10^5/M
Q9BVA1 BXGT020142 Tubulin beta-2B chain reviewed - TUBB2B Ki '=' 1600 10^5/M
Q13885 BXGT013400 Tubulin beta-2A chain reviewed Cellular structure TUBB2A Ki '=' 1600 10^5/M
Q6PEY2 BXGT016465 Tubulin alpha-3E chain reviewed Cellular structure TUBA3E Ki '=' 1600 10^5/M
Q9BQE3 BXGT020109 Tubulin alpha-1C chain reviewed Cellular structure TUBA1C Ki '=' 1600 10^5/M
P68363 BXGT011594 Tubulin alpha-1B chain reviewed Cellular structure TUBA1B Ki '=' 1600 10^5/M
P07437 BXGT006624 Tubulin beta chain reviewed Cellular structure TUBB Ki '=' 1600 10^5/M
Q3ZCM7 BXGT014551 Tubulin beta-8 chain reviewed - TUBB8 Ki '=' 1600 10^5/M
P04350 BXGT006193 Tubulin beta-4A chain reviewed Cellular structure TUBB4A Ki '=' 1600 10^5/M
Q71U36 BXGT016705 Tubulin alpha-1A chain reviewed Cellular structure TUBA1A Ki '=' 1600 10^5/M
Q13509 BXGT013366 Tubulin beta-3 chain reviewed Cellular structure TUBB3 Ki '=' 1600 10^5/M
P68366 BXGT011595 Tubulin alpha-4A chain reviewed Cellular structure TUBA4A Ki '=' 1600 10^5/M
P0DPH7 BXGT007527 Tubulin alpha-3C chain reviewed - TUBA3C Ki '=' 1600 10^5/M
Q9H4B7 BXGT020475 Tubulin beta-1 chain reviewed Cellular structure TUBB1 Ki '=' 1600 10^5/M
P68371 BXGT011597 Tubulin beta-4B chain reviewed Cellular structure TUBB4B Ki '=' 1600 10^5/M
P10828 BXGT007624 Thyroid hormone receptor beta reviewed Nuclear receptor THRB Potency - 1 nM
P02550 BXGT005891 Tubulin alpha-1A chain reviewed - TUBA1A Inhibition '=' 4 %
P02550 BXGT005891 Tubulin alpha-1A chain reviewed - TUBA1A Inhibition '=' 0 %
P25021 BXGT009004 Histamine H2 receptor reviewed G-protein coupled receptor HRH2 IC50 - - -
P03956 BXGT006120 Interstitial collagenase reviewed Enzyme MMP1 Ki - - -
Q9BUF5 BXGT020135 Tubulin beta-6 chain reviewed Cellular structure TUBB6 IC50 '=' 4200 nM
Q9BVA1 BXGT020142 Tubulin beta-2B chain reviewed - TUBB2B IC50 '=' 4200 nM
Q13885 BXGT013400 Tubulin beta-2A chain reviewed Cellular structure TUBB2A IC50 '=' 4200 nM
Q6PEY2 BXGT016465 Tubulin alpha-3E chain reviewed Cellular structure TUBA3E IC50 '=' 4200 nM
Q9BQE3 BXGT020109 Tubulin alpha-1C chain reviewed Cellular structure TUBA1C IC50 '=' 4200 nM
P68363 BXGT011594 Tubulin alpha-1B chain reviewed Cellular structure TUBA1B IC50 '=' 4200 nM
P07437 BXGT006624 Tubulin beta chain reviewed Cellular structure TUBB IC50 '=' 4200 nM
Q3ZCM7 BXGT014551 Tubulin beta-8 chain reviewed - TUBB8 IC50 '=' 4200 nM
P04350 BXGT006193 Tubulin beta-4A chain reviewed Cellular structure TUBB4A IC50 '=' 4200 nM
Q71U36 BXGT016705 Tubulin alpha-1A chain reviewed Cellular structure TUBA1A IC50 '=' 4200 nM
Q13509 BXGT013366 Tubulin beta-3 chain reviewed Cellular structure TUBB3 IC50 '=' 4200 nM
P68366 BXGT011595 Tubulin alpha-4A chain reviewed Cellular structure TUBA4A IC50 '=' 4200 nM
P0DPH7 BXGT007527 Tubulin alpha-3C chain reviewed - TUBA3C IC50 '=' 4200 nM
Q9H4B7 BXGT020475 Tubulin beta-1 chain reviewed Cellular structure TUBB1 IC50 '=' 4200 nM
P68371 BXGT011597 Tubulin beta-4B chain reviewed Cellular structure TUBB4B IC50 '=' 4200 nM
P83916 BXGT012025 Chromobox protein homolog 1 reviewed Epigenetic regulator CBX1 Potency - 3 nM
Q9NUW8 BXGT021219 Tyrosyl-DNA phosphodiesterase 1 reviewed Enzyme TDP1 Potency - 66 nM
P02550 BXGT005891 Tubulin alpha-1A chain reviewed - TUBA1A IC50 '=' 2100 nM
P02554 BXGT005892 Tubulin beta chain reviewed - IC50 '=' 2100 nM
Q9BUF5 BXGT020135 Tubulin beta-6 chain reviewed Cellular structure TUBB6 IC50 '=' 2700 nM
Q9BVA1 BXGT020142 Tubulin beta-2B chain reviewed - TUBB2B IC50 '=' 2700 nM
Q13885 BXGT013400 Tubulin beta-2A chain reviewed Cellular structure TUBB2A IC50 '=' 2700 nM
Q6PEY2 BXGT016465 Tubulin alpha-3E chain reviewed Cellular structure TUBA3E IC50 '=' 2700 nM
Q9BQE3 BXGT020109 Tubulin alpha-1C chain reviewed Cellular structure TUBA1C IC50 '=' 2700 nM
P68363 BXGT011594 Tubulin alpha-1B chain reviewed Cellular structure TUBA1B IC50 '=' 2700 nM
P07437 BXGT006624 Tubulin beta chain reviewed Cellular structure TUBB IC50 '=' 2700 nM
Q3ZCM7 BXGT014551 Tubulin beta-8 chain reviewed - TUBB8 IC50 '=' 2700 nM
P04350 BXGT006193 Tubulin beta-4A chain reviewed Cellular structure TUBB4A IC50 '=' 2700 nM
Q71U36 BXGT016705 Tubulin alpha-1A chain reviewed Cellular structure TUBA1A IC50 '=' 2700 nM
Q13509 BXGT013366 Tubulin beta-3 chain reviewed Cellular structure TUBB3 IC50 '=' 2700 nM
P68366 BXGT011595 Tubulin alpha-4A chain reviewed Cellular structure TUBA4A IC50 '=' 2700 nM
P0DPH7 BXGT007527 Tubulin alpha-3C chain reviewed - TUBA3C IC50 '=' 2700 nM
Q9H4B7 BXGT020475 Tubulin beta-1 chain reviewed Cellular structure TUBB1 IC50 '=' 2700 nM
P68371 BXGT011597 Tubulin beta-4B chain reviewed Cellular structure TUBB4B IC50 '=' 2700 nM
P21447 BXGT008651 ATP-dependent translocase ABCB1 reviewed - Abcb1a IC50 '>' 50000 nM
Q9BUF5 BXGT020135 Tubulin beta-6 chain reviewed Cellular structure TUBB6 IC50 '=' 2600 nM
Q9BVA1 BXGT020142 Tubulin beta-2B chain reviewed - TUBB2B IC50 '=' 2600 nM
Q13885 BXGT013400 Tubulin beta-2A chain reviewed Cellular structure TUBB2A IC50 '=' 2600 nM
Q6PEY2 BXGT016465 Tubulin alpha-3E chain reviewed Cellular structure TUBA3E IC50 '=' 2600 nM
Q9BQE3 BXGT020109 Tubulin alpha-1C chain reviewed Cellular structure TUBA1C IC50 '=' 2600 nM
P68363 BXGT011594 Tubulin alpha-1B chain reviewed Cellular structure TUBA1B IC50 '=' 2600 nM
P07437 BXGT006624 Tubulin beta chain reviewed Cellular structure TUBB IC50 '=' 2600 nM
Q3ZCM7 BXGT014551 Tubulin beta-8 chain reviewed - TUBB8 IC50 '=' 2600 nM
P04350 BXGT006193 Tubulin beta-4A chain reviewed Cellular structure TUBB4A IC50 '=' 2600 nM
Q71U36 BXGT016705 Tubulin alpha-1A chain reviewed Cellular structure TUBA1A IC50 '=' 2600 nM
Q13509 BXGT013366 Tubulin beta-3 chain reviewed Cellular structure TUBB3 IC50 '=' 2600 nM
P68366 BXGT011595 Tubulin alpha-4A chain reviewed Cellular structure TUBA4A IC50 '=' 2600 nM
P0DPH7 BXGT007527 Tubulin alpha-3C chain reviewed - TUBA3C IC50 '=' 2600 nM
Q9H4B7 BXGT020475 Tubulin beta-1 chain reviewed Cellular structure TUBB1 IC50 '=' 2600 nM
P68371 BXGT011597 Tubulin beta-4B chain reviewed Cellular structure TUBB4B IC50 '=' 2600 nM
P18825 BXGT008426 Alpha-2C adrenergic receptor reviewed G-protein coupled receptor ADRA2C IC50 - - -
P02550 BXGT005891 Tubulin alpha-1A chain reviewed - TUBA1A IC50 '=' 1060 nM
P02554 BXGT005892 Tubulin beta chain reviewed - IC50 '=' 1060 nM
Q9NR56 BXGT021179 Muscleblind-like protein 1 reviewed Nucleic acid binding MBNL1 Potency - 15848 nM
O75496 BXGT005132 Geminin reviewed - GMNN Potency - 206 nM
P37288 BXGT009977 Vasopressin V1a receptor reviewed G-protein coupled receptor AVPR1A IC50 - - -
P27695 BXGT009199 DNA-(apurinic or apyrimidinic site) lyase reviewed - APEX1 Potency - 5 nM
Q6B856 BXGT016212 Tubulin beta-2B chain reviewed - TUBB2B Stimulation '=' 235 %
Q9BUF5 BXGT020135 Tubulin beta-6 chain reviewed Cellular structure TUBB6 IC50 '=' 800000 nM
Q9BVA1 BXGT020142 Tubulin beta-2B chain reviewed - TUBB2B IC50 '=' 800000 nM
Q13885 BXGT013400 Tubulin beta-2A chain reviewed Cellular structure TUBB2A IC50 '=' 800000 nM
Q6PEY2 BXGT016465 Tubulin alpha-3E chain reviewed Cellular structure TUBA3E IC50 '=' 800000 nM
Q9BQE3 BXGT020109 Tubulin alpha-1C chain reviewed Cellular structure TUBA1C IC50 '=' 800000 nM
P68363 BXGT011594 Tubulin alpha-1B chain reviewed Cellular structure TUBA1B IC50 '=' 800000 nM
P07437 BXGT006624 Tubulin beta chain reviewed Cellular structure TUBB IC50 '=' 800000 nM
Q3ZCM7 BXGT014551 Tubulin beta-8 chain reviewed - TUBB8 IC50 '=' 800000 nM
P04350 BXGT006193 Tubulin beta-4A chain reviewed Cellular structure TUBB4A IC50 '=' 800000 nM
Q71U36 BXGT016705 Tubulin alpha-1A chain reviewed Cellular structure TUBA1A IC50 '=' 800000 nM
Q13509 BXGT013366 Tubulin beta-3 chain reviewed Cellular structure TUBB3 IC50 '=' 800000 nM
P68366 BXGT011595 Tubulin alpha-4A chain reviewed Cellular structure TUBA4A IC50 '=' 800000 nM
P0DPH7 BXGT007527 Tubulin alpha-3C chain reviewed - TUBA3C IC50 '=' 800000 nM
Q9H4B7 BXGT020475 Tubulin beta-1 chain reviewed Cellular structure TUBB1 IC50 '=' 800000 nM
P68371 BXGT011597 Tubulin beta-4B chain reviewed Cellular structure TUBB4B IC50 '=' 800000 nM
Q6B856 BXGT016212 Tubulin beta-2B chain reviewed - TUBB2B Ki '=' 780 nM
Q862F3 BXGT017581 Similar to alpha-tubulin isoform 1 unreviewed - ITP '=' 27 %
Q862L2 BXGT017582 Similar to alpha-tubulin isoform 1 unreviewed - ITP '=' 27 %
Q6B856 BXGT016212 Tubulin beta-2B chain reviewed - TUBB2B ITP '=' 27 %
P15917 BXGT008169 Lethal factor reviewed - lef Potency '=' 50 nM
O15648 BXGT004185 ATP-dependent 6-phosphofructokinase reviewed - pfk Potency - 37 nM
P08183 BXGT006741 ATP-dependent translocase ABCB1 reviewed Transporter ABCB1 Ratio_ATPase activity '=' 1 -
Q9BUF5 BXGT020135 Tubulin beta-6 chain reviewed Cellular structure TUBB6 Binding '=' 56 %
Q9BVA1 BXGT020142 Tubulin beta-2B chain reviewed - TUBB2B Binding '=' 56 %
Q13885 BXGT013400 Tubulin beta-2A chain reviewed Cellular structure TUBB2A Binding '=' 56 %
Q6PEY2 BXGT016465 Tubulin alpha-3E chain reviewed Cellular structure TUBA3E Binding '=' 56 %
Q9BQE3 BXGT020109 Tubulin alpha-1C chain reviewed Cellular structure TUBA1C Binding '=' 56 %
P68363 BXGT011594 Tubulin alpha-1B chain reviewed Cellular structure TUBA1B Binding '=' 56 %
P07437 BXGT006624 Tubulin beta chain reviewed Cellular structure TUBB Binding '=' 56 %
Q3ZCM7 BXGT014551 Tubulin beta-8 chain reviewed - TUBB8 Binding '=' 56 %
P04350 BXGT006193 Tubulin beta-4A chain reviewed Cellular structure TUBB4A Binding '=' 56 %
Q71U36 BXGT016705 Tubulin alpha-1A chain reviewed Cellular structure TUBA1A Binding '=' 56 %
Q13509 BXGT013366 Tubulin beta-3 chain reviewed Cellular structure TUBB3 Binding '=' 56 %
P68366 BXGT011595 Tubulin alpha-4A chain reviewed Cellular structure TUBA4A Binding '=' 56 %
P0DPH7 BXGT007527 Tubulin alpha-3C chain reviewed - TUBA3C Binding '=' 56 %
Q9H4B7 BXGT020475 Tubulin beta-1 chain reviewed Cellular structure TUBB1 Binding '=' 56 %
P68371 BXGT011597 Tubulin beta-4B chain reviewed Cellular structure TUBB4B Binding '=' 56 %
Q862F3 BXGT017581 Similar to alpha-tubulin isoform 1 unreviewed - IC50 '=' 4900 nM
Q862L2 BXGT017582 Similar to alpha-tubulin isoform 1 unreviewed - IC50 '=' 4900 nM
Q6B856 BXGT016212 Tubulin beta-2B chain reviewed - TUBB2B IC50 '=' 4900 nM
Q9BUF5 BXGT020135 Tubulin beta-6 chain reviewed Cellular structure TUBB6 Activity '=' 32 %
Q9BVA1 BXGT020142 Tubulin beta-2B chain reviewed - TUBB2B Activity '=' 32 %
Q13885 BXGT013400 Tubulin beta-2A chain reviewed Cellular structure TUBB2A Activity '=' 32 %
Q6PEY2 BXGT016465 Tubulin alpha-3E chain reviewed Cellular structure TUBA3E Activity '=' 32 %
Q9BQE3 BXGT020109 Tubulin alpha-1C chain reviewed Cellular structure TUBA1C Activity '=' 32 %
P68363 BXGT011594 Tubulin alpha-1B chain reviewed Cellular structure TUBA1B Activity '=' 32 %
P07437 BXGT006624 Tubulin beta chain reviewed Cellular structure TUBB Activity '=' 32 %
Q3ZCM7 BXGT014551 Tubulin beta-8 chain reviewed - TUBB8 Activity '=' 32 %
P04350 BXGT006193 Tubulin beta-4A chain reviewed Cellular structure TUBB4A Activity '=' 32 %
Q71U36 BXGT016705 Tubulin alpha-1A chain reviewed Cellular structure TUBA1A Activity '=' 32 %
Q13509 BXGT013366 Tubulin beta-3 chain reviewed Cellular structure TUBB3 Activity '=' 32 %
P68366 BXGT011595 Tubulin alpha-4A chain reviewed Cellular structure TUBA4A Activity '=' 32 %
P0DPH7 BXGT007527 Tubulin alpha-3C chain reviewed - TUBA3C Activity '=' 32 %
Q9H4B7 BXGT020475 Tubulin beta-1 chain reviewed Cellular structure TUBB1 Activity '=' 32 %
P68371 BXGT011597 Tubulin beta-4B chain reviewed Cellular structure TUBB4B Activity '=' 32 %
Q9BUF5 BXGT020135 Tubulin beta-6 chain reviewed Cellular structure TUBB6 IC50 '=' 2900 nM
Q9BVA1 BXGT020142 Tubulin beta-2B chain reviewed - TUBB2B IC50 '=' 2900 nM
Q13885 BXGT013400 Tubulin beta-2A chain reviewed Cellular structure TUBB2A IC50 '=' 2900 nM
Q6PEY2 BXGT016465 Tubulin alpha-3E chain reviewed Cellular structure TUBA3E IC50 '=' 2900 nM
Q9BQE3 BXGT020109 Tubulin alpha-1C chain reviewed Cellular structure TUBA1C IC50 '=' 2900 nM
P68363 BXGT011594 Tubulin alpha-1B chain reviewed Cellular structure TUBA1B IC50 '=' 2900 nM
P07437 BXGT006624 Tubulin beta chain reviewed Cellular structure TUBB IC50 '=' 2900 nM
Q3ZCM7 BXGT014551 Tubulin beta-8 chain reviewed - TUBB8 IC50 '=' 2900 nM
P04350 BXGT006193 Tubulin beta-4A chain reviewed Cellular structure TUBB4A IC50 '=' 2900 nM
Q71U36 BXGT016705 Tubulin alpha-1A chain reviewed Cellular structure TUBA1A IC50 '=' 2900 nM
Q13509 BXGT013366 Tubulin beta-3 chain reviewed Cellular structure TUBB3 IC50 '=' 2900 nM
P68366 BXGT011595 Tubulin alpha-4A chain reviewed Cellular structure TUBA4A IC50 '=' 2900 nM
P0DPH7 BXGT007527 Tubulin alpha-3C chain reviewed - TUBA3C IC50 '=' 2900 nM
Q9H4B7 BXGT020475 Tubulin beta-1 chain reviewed Cellular structure TUBB1 IC50 '=' 2900 nM
P68371 BXGT011597 Tubulin beta-4B chain reviewed Cellular structure TUBB4B IC50 '=' 2900 nM
Q862F3 BXGT017581 Similar to alpha-tubulin isoform 1 unreviewed - IC50 '=' 2500 nM
Q862L2 BXGT017582 Similar to alpha-tubulin isoform 1 unreviewed - IC50 '=' 2500 nM
Q6B856 BXGT016212 Tubulin beta-2B chain reviewed - TUBB2B IC50 '=' 2500 nM
Q862F3 BXGT017581 Similar to alpha-tubulin isoform 1 unreviewed - Inhibition '=' 80 %
Q862L2 BXGT017582 Similar to alpha-tubulin isoform 1 unreviewed - Inhibition '=' 80 %
Q6B856 BXGT016212 Tubulin beta-2B chain reviewed - TUBB2B Inhibition '=' 80 %
Q862F3 BXGT017581 Similar to alpha-tubulin isoform 1 unreviewed - IC50 '=' 1340 nM
Q862L2 BXGT017582 Similar to alpha-tubulin isoform 1 unreviewed - IC50 '=' 1340 nM
Q6B856 BXGT016212 Tubulin beta-2B chain reviewed - TUBB2B IC50 '=' 1340 nM
Q862F3 BXGT017581 Similar to alpha-tubulin isoform 1 unreviewed - IC50 '=' 2620 nM
Q6B856 BXGT016212 Tubulin beta-2B chain reviewed - TUBB2B IC50 '=' 2620 nM
P02550 BXGT005891 Tubulin alpha-1A chain reviewed - TUBA1A IC50 '=' 7850 nM
P02554 BXGT005892 Tubulin beta chain reviewed - IC50 '=' 7850 nM
Q16236 BXGT013624 Nuclear factor erythroid 2-related factor 2 reviewed Enzyme NFE2L2 Potency - 188 nM
P21447 BXGT008651 ATP-dependent translocase ABCB1 reviewed - Abcb1a Ratio '=' 0 -
O75496 BXGT005132 Geminin reviewed - GMNN Potency - 4 nM
P39748 BXGT010134 Flap endonuclease 1 reviewed Enzyme FEN1 Potency - 6701 nM
P02550 BXGT005891 Tubulin alpha-1A chain reviewed - TUBA1A Ka '=' 100000000 M-1
P08684 BXGT006812 Cytochrome P450 3A4 reviewed Enzyme CYP3A4 Ki - - -
P25101 BXGT009018 Endothelin-1 receptor reviewed G-protein coupled receptor EDNRA Ki - - -
P18089 BXGT008379 Alpha-2B adrenergic receptor reviewed G-protein coupled receptor ADRA2B Ki - - -
P50052 BXGT010768 Type-2 angiotensin II receptor reviewed G-protein coupled receptor AGTR2 Ki - - -
P41597 BXGT010268 C-C chemokine receptor type 2 reviewed - CCR2 Ki - - -
Q862F3 BXGT017581 Similar to alpha-tubulin isoform 1 unreviewed - IC50 '=' 4200 nM
Q862L2 BXGT017582 Similar to alpha-tubulin isoform 1 unreviewed - IC50 '=' 4200 nM
Q6B856 BXGT016212 Tubulin beta-2B chain reviewed - TUBB2B IC50 '=' 4200 nM
P02550 BXGT005891 Tubulin alpha-1A chain reviewed - TUBA1A Inhibitory binding '=' 98 %
P29274 BXGT009327 Adenosine receptor A2a reviewed G-protein coupled receptor ADORA2A Ki - - -
P0DMS8 BXGT007506 Adenosine receptor A3 reviewed G-protein coupled receptor ADORA3 IC50 - - -
P0DMS8 BXGT007506 Adenosine receptor A3 reviewed G-protein coupled receptor ADORA3 Ki - - -
P25100 BXGT009017 Alpha-1D adrenergic receptor reviewed G-protein coupled receptor ADRA1D Ki - - -
P08913 BXGT006841 Alpha-2A adrenergic receptor reviewed G-protein coupled receptor ADRA2A Ki - - -
P07550 BXGT006636 Beta-2 adrenergic receptor reviewed G-protein coupled receptor ADRB2 IC50 - - -
P07550 BXGT006636 Beta-2 adrenergic receptor reviewed G-protein coupled receptor ADRB2 Ki - - -
P23975 BXGT008935 Sodium-dependent noradrenaline transporter reviewed Transporter SLC6A2 Ki - - -
P21554 BXGT008662 Cannabinoid receptor 1 reviewed G-protein coupled receptor CNR1 IC50 - - -
P25025 BXGT009006 C-X-C chemokine receptor type 2 reviewed G-protein coupled receptor CXCR2 IC50 - - -
P05177 BXGT006336 Cytochrome P450 1A2 reviewed Enzyme CYP1A2 IC50 - - -
P35462 BXGT009835 D(3) dopamine receptor reviewed G-protein coupled receptor DRD3 IC50 - - -
P21728 BXGT008686 D(1A) dopamine receptor reviewed G-protein coupled receptor DRD1 Ki - - -
Q6B856 BXGT016212 Tubulin beta-2B chain reviewed - TUBB2B GTPase Activity '=' 6 -
P10635 BXGT007595 Cytochrome P450 2D6 reviewed - CYP2D6 AC50 '=' 794 nM
P02545 BXGT005889 Prelamin-A/C reviewed - LMNA Potency '=' 125 nM
Q9Y271 BXGT022222 Cysteinyl leukotriene receptor 1 reviewed G-protein coupled receptor CYSLTR1 Ki - - -
P32245 BXGT009614 Melanocortin receptor 4 reviewed G-protein coupled receptor MC4R IC50 - - -
P08172 BXGT006737 Muscarinic acetylcholine receptor M2 reviewed G-protein coupled receptor CHRM2 IC50 - - -
P06239 BXGT006427 Tyrosine-protein kinase Lck reviewed Kinase LCK Ki - - -
Q8BW75 BXGT017924 Amine oxidase [flavin-containing] B reviewed - Maob Activity - - -
P10635 BXGT007595 Cytochrome P450 2D6 reviewed - CYP2D6 IC50 - - -
P00811 BXGT005666 Beta-lactamase reviewed - ampC Potency '=' 5011 nM
P11309 BXGT007685 Serine/threonine-protein kinase pim-1 reviewed Kinase PIM1 Inhibition '=' 65 %
Q862F3 BXGT017581 Similar to alpha-tubulin isoform 1 unreviewed - Activity '=' 1 -
Q862L2 BXGT017582 Similar to alpha-tubulin isoform 1 unreviewed - Activity '=' 1 -
Q6B856 BXGT016212 Tubulin beta-2B chain reviewed - TUBB2B Activity '=' 1 -
Q16236 BXGT013624 Nuclear factor erythroid 2-related factor 2 reviewed Enzyme NFE2L2 Potency - 58 nM
P08183 BXGT006741 ATP-dependent translocase ABCB1 reviewed Transporter ABCB1 Activity '=' 0 nM/mg*min
P08684 BXGT006812 Cytochrome P450 3A4 reviewed Enzyme CYP3A4 AC50 '=' 2511 nM
Q862F3 BXGT017581 Similar to alpha-tubulin isoform 1 unreviewed - Activity - - -
Q862L2 BXGT017582 Similar to alpha-tubulin isoform 1 unreviewed - Activity - - -
Q6B856 BXGT016212 Tubulin beta-2B chain reviewed - TUBB2B Activity - - -
P33261 BXGT009707 Cytochrome P450 2C19 reviewed - CYP2C19 AC50 '=' 12589 nM
P11712 BXGT007738 Cytochrome P450 2C9 reviewed - CYP2C9 Inhibition - - -
Q96RI1 BXGT019727 Bile acid receptor reviewed Nuclear receptor NR1H4 Potency - 25 nM
Q16236 BXGT013624 Nuclear factor erythroid 2-related factor 2 reviewed Enzyme NFE2L2 Potency - 73 nM
O75496 BXGT005132 Geminin reviewed - GMNN Potency - 53 nM
Q03181 BXGT012701 Peroxisome proliferator-activated receptor delta reviewed Nuclear receptor PPARD Potency - 112 nM
P02545 BXGT005889 Prelamin-A/C reviewed - LMNA Potency '=' 70 nM
P33261 BXGT009707 Cytochrome P450 2C19 reviewed - CYP2C19 Ki - - -
P08684 BXGT006812 Cytochrome P450 3A4 reviewed Enzyme CYP3A4 IC50 - - -
P51843 BXGT010897 Nuclear receptor subfamily 0 group B member 1 reviewed Nuclear receptor NR0B1 IC50 '>' 67568 nM
P81908 BXGT011959 Cholinesterase reviewed - BCHE Inhibition '=' 0 %
Q862F3 BXGT017581 Similar to alpha-tubulin isoform 1 unreviewed - Inhibition - - -
Q6B856 BXGT016212 Tubulin beta-2B chain reviewed - TUBB2B Inhibition - - -
Q9NUW8 BXGT021219 Tyrosyl-DNA phosphodiesterase 1 reviewed Enzyme TDP1 Potency - 266 nM
Q9BUF5 BXGT020135 Tubulin beta-6 chain reviewed Cellular structure TUBB6 IC50 '=' 2210 nM
Q9BVA1 BXGT020142 Tubulin beta-2B chain reviewed - TUBB2B IC50 '=' 2210 nM
Q13885 BXGT013400 Tubulin beta-2A chain reviewed Cellular structure TUBB2A IC50 '=' 2210 nM
Q6PEY2 BXGT016465 Tubulin alpha-3E chain reviewed Cellular structure TUBA3E IC50 '=' 2210 nM
Q9BQE3 BXGT020109 Tubulin alpha-1C chain reviewed Cellular structure TUBA1C IC50 '=' 2210 nM
P68363 BXGT011594 Tubulin alpha-1B chain reviewed Cellular structure TUBA1B IC50 '=' 2210 nM
P07437 BXGT006624 Tubulin beta chain reviewed Cellular structure TUBB IC50 '=' 2210 nM
Q3ZCM7 BXGT014551 Tubulin beta-8 chain reviewed - TUBB8 IC50 '=' 2210 nM
P04350 BXGT006193 Tubulin beta-4A chain reviewed Cellular structure TUBB4A IC50 '=' 2210 nM
Q71U36 BXGT016705 Tubulin alpha-1A chain reviewed Cellular structure TUBA1A IC50 '=' 2210 nM
Q13509 BXGT013366 Tubulin beta-3 chain reviewed Cellular structure TUBB3 IC50 '=' 2210 nM
P68366 BXGT011595 Tubulin alpha-4A chain reviewed Cellular structure TUBA4A IC50 '=' 2210 nM
P0DPH7 BXGT007527 Tubulin alpha-3C chain reviewed - TUBA3C IC50 '=' 2210 nM
Q9H4B7 BXGT020475 Tubulin beta-1 chain reviewed Cellular structure TUBB1 IC50 '=' 2210 nM
P68371 BXGT011597 Tubulin beta-4B chain reviewed Cellular structure TUBB4B IC50 '=' 2210 nM
P30411 BXGT009424 B2 bradykinin receptor reviewed G-protein coupled receptor BDKRB2 IC50 - - -
P21554 BXGT008662 Cannabinoid receptor 1 reviewed G-protein coupled receptor CNR1 Ki - - -
P00918 BXGT005690 Carbonic anhydrase 2 reviewed - CA2 Ki - - -
P51681 BXGT010878 C-C chemokine receptor type 5 reviewed G-protein coupled receptor CCR5 IC50 - - -
P32238 BXGT009611 Cholecystokinin receptor type A reviewed G-protein coupled receptor CCKAR IC50 - - -
Q862F3 BXGT017581 Similar to alpha-tubulin isoform 1 unreviewed - Ka '=' 1 10'7/M
Q862L2 BXGT017582 Similar to alpha-tubulin isoform 1 unreviewed - Ka '=' 1 10'7/M
Q6B856 BXGT016212 Tubulin beta-2B chain reviewed - TUBB2B Ka '=' 1 10'7/M
Q9BUF5 BXGT020135 Tubulin beta-6 chain reviewed Cellular structure TUBB6 Activity '=' 33 %
Q9BVA1 BXGT020142 Tubulin beta-2B chain reviewed - TUBB2B Activity '=' 33 %
Q13885 BXGT013400 Tubulin beta-2A chain reviewed Cellular structure TUBB2A Activity '=' 33 %
Q6PEY2 BXGT016465 Tubulin alpha-3E chain reviewed Cellular structure TUBA3E Activity '=' 33 %
Q9BQE3 BXGT020109 Tubulin alpha-1C chain reviewed Cellular structure TUBA1C Activity '=' 33 %
P68363 BXGT011594 Tubulin alpha-1B chain reviewed Cellular structure TUBA1B Activity '=' 33 %
P07437 BXGT006624 Tubulin beta chain reviewed Cellular structure TUBB Activity '=' 33 %
Q3ZCM7 BXGT014551 Tubulin beta-8 chain reviewed - TUBB8 Activity '=' 33 %
P04350 BXGT006193 Tubulin beta-4A chain reviewed Cellular structure TUBB4A Activity '=' 33 %
Q71U36 BXGT016705 Tubulin alpha-1A chain reviewed Cellular structure TUBA1A Activity '=' 33 %
Q13509 BXGT013366 Tubulin beta-3 chain reviewed Cellular structure TUBB3 Activity '=' 33 %
P68366 BXGT011595 Tubulin alpha-4A chain reviewed Cellular structure TUBA4A Activity '=' 33 %
P0DPH7 BXGT007527 Tubulin alpha-3C chain reviewed - TUBA3C Activity '=' 33 %
Q9H4B7 BXGT020475 Tubulin beta-1 chain reviewed Cellular structure TUBB1 Activity '=' 33 %
P68371 BXGT011597 Tubulin beta-4B chain reviewed Cellular structure TUBB4B Activity '=' 33 %
O70528 BXGT005068 5-hydroxytryptamine receptor 4 reviewed - HTR4 IC50 - - -
P24557 BXGT008976 Thromboxane-A synthase reviewed - TBXAS1 IC50 - - -
P25929 BXGT009078 Neuropeptide Y receptor type 1 reviewed G-protein coupled receptor NPY1R IC50 - - -
P04626 BXGT006238 Receptor tyrosine-protein kinase erbB-2 reviewed Kinase ERBB2 IC50 - - -
P04035 BXGT006129 3-hydroxy-3-methylglutaryl-coenzyme A reductase reviewed - HMGCR Ki - - -
P20309 BXGT008562 Muscarinic acetylcholine receptor M3 reviewed G-protein coupled receptor CHRM3 IC50 - - -
O76074 BXGT005174 cGMP-specific 3',5'-cyclic phosphodiesterase reviewed - PDE5A IC50 - - -
Q16236 BXGT013624 Nuclear factor erythroid 2-related factor 2 reviewed Enzyme NFE2L2 Potency - 75 nM
P13945 BXGT007972 Beta-3 adrenergic receptor reviewed G-protein coupled receptor ADRB3 Ki - - -
P00918 BXGT005690 Carbonic anhydrase 2 reviewed - CA2 IC50 - - -
P25094 BXGT009014 Peripheral myelin protein 22 reviewed - Pmp22 Potency - 89 nM
P15127 BXGT008085 Insulin receptor reviewed - Insr Ki - - -
P21397 BXGT008644 Amine oxidase [flavin-containing] A reviewed - MAOA Ki - - -
P11229 BXGT007676 Muscarinic acetylcholine receptor M1 reviewed G-protein coupled receptor CHRM1 Ki - - -
P23219 BXGT008837 Prostaglandin G/H synthase 1 reviewed Enzyme PTGS1 Ki - - -
O42275 BXGT004559 Acetylcholinesterase reviewed - ache Inhibition '=' 0 %
P04150 BXGT006154 Glucocorticoid receptor reviewed Nuclear receptor NR3C1 Potency - 707 nM
Q9NUW8 BXGT021219 Tyrosyl-DNA phosphodiesterase 1 reviewed Enzyme TDP1 Potency - 188 nM
P0A6C1 BXGT007045 Endonuclease 4 reviewed - nfo Potency '=' 2511 nM
P02550 BXGT005891 Tubulin alpha-1A chain reviewed - TUBA1A IC50 '=' 8120 nM
P02554 BXGT005892 Tubulin beta chain reviewed - IC50 '=' 8120 nM
Q9Y271 BXGT022222 Cysteinyl leukotriene receptor 1 reviewed G-protein coupled receptor CYSLTR1 IC50 - - -
P08246 BXGT006756 Neutrophil elastase reviewed Enzyme ELANE IC50 - - -
P15917 BXGT008169 Lethal factor reviewed - lef Potency '=' 100 nM
P17252 BXGT008294 Protein kinase C alpha type reviewed Kinase PRKCA IC50 - - -
P27361 BXGT009176 Mitogen-activated protein kinase 3 reviewed Kinase MAPK3 IC50 - - -
P08183 BXGT006741 ATP-dependent translocase ABCB1 reviewed Transporter ABCB1 Km '=' 45000 nM
P00533 BXGT005575 Epidermal growth factor receptor reviewed Kinase EGFR Ki - - -
P06241 BXGT006429 Tyrosine-protein kinase Fyn reviewed Kinase FYN Ki - - -
P19327 BXGT008472 5-hydroxytryptamine receptor 1A reviewed - Htr1a Ki - - -
P15207 BXGT008096 Androgen receptor reviewed - Ar Ki - - -
P35372 BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 IC50 - - -
Q9NPD5 BXGT021151 Solute carrier organic anion transporter family member 1B3 reviewed Transporter SLCO1B3 Inhibition '=' -3 %
P10275 BXGT007552 Androgen receptor reviewed Nuclear receptor AR Potency - 11 nM
P50406 BXGT010796 5-hydroxytryptamine receptor 6 reviewed G-protein coupled receptor HTR6 Ki - - -
P15207 BXGT008096 Androgen receptor reviewed - Ar IC50 - - -
P35367 BXGT009821 Histamine H1 receptor reviewed G-protein coupled receptor HRH1 Ki - - -
P25021 BXGT009004 Histamine H2 receptor reviewed G-protein coupled receptor HRH2 Ki - - -
O76074 BXGT005174 cGMP-specific 3',5'-cyclic phosphodiesterase reviewed - PDE5A Ki - - -
Q690N0 BXGT016199 Progesterone receptor unreviewed - PGR Ki - - -
P29466 BXGT009349 Caspase-1 reviewed Enzyme CASP1 Ki - - -
P19793 BXGT008515 Retinoic acid receptor RXR-alpha reviewed Nuclear receptor RXRA Potency - 31 nM
Q08201 BXGT012967 Phosphatidylcholine translocator ABCB4 reviewed - Abcb4 Activity - - -
P10635 BXGT007595 Cytochrome P450 2D6 reviewed - CYP2D6 Potency '=' 794 nM
P08183 BXGT006741 ATP-dependent translocase ABCB1 reviewed Transporter ABCB1 Activity '=' 8 %
O95342 BXGT005373 Bile salt export pump reviewed Transporter ABCB11 IC50 '>' 135000 nM
P04637 BXGT006243 Cellular tumor antigen p53 reviewed Transcription factor TP53 Potency '=' 1584 nM
P51449 BXGT010846 Nuclear receptor ROR-gamma reviewed Nuclear receptor RORC Potency - 334 nM
Q9BUF5 BXGT020135 Tubulin beta-6 chain reviewed Cellular structure TUBB6 Activity '=' 4 uM
Q9BVA1 BXGT020142 Tubulin beta-2B chain reviewed - TUBB2B Activity '=' 4 uM
Q13885 BXGT013400 Tubulin beta-2A chain reviewed Cellular structure TUBB2A Activity '=' 4 uM
Q6PEY2 BXGT016465 Tubulin alpha-3E chain reviewed Cellular structure TUBA3E Activity '=' 4 uM
Q9BQE3 BXGT020109 Tubulin alpha-1C chain reviewed Cellular structure TUBA1C Activity '=' 4 uM
P68363 BXGT011594 Tubulin alpha-1B chain reviewed Cellular structure TUBA1B Activity '=' 4 uM
P07437 BXGT006624 Tubulin beta chain reviewed Cellular structure TUBB Activity '=' 4 uM
Q3ZCM7 BXGT014551 Tubulin beta-8 chain reviewed - TUBB8 Activity '=' 4 uM
P04350 BXGT006193 Tubulin beta-4A chain reviewed Cellular structure TUBB4A Activity '=' 4 uM
Q71U36 BXGT016705 Tubulin alpha-1A chain reviewed Cellular structure TUBA1A Activity '=' 4 uM
Q13509 BXGT013366 Tubulin beta-3 chain reviewed Cellular structure TUBB3 Activity '=' 4 uM
P68366 BXGT011595 Tubulin alpha-4A chain reviewed Cellular structure TUBA4A Activity '=' 4 uM
P0DPH7 BXGT007527 Tubulin alpha-3C chain reviewed - TUBA3C Activity '=' 4 uM
Q9H4B7 BXGT020475 Tubulin beta-1 chain reviewed Cellular structure TUBB1 Activity '=' 4 uM
P68371 BXGT011597 Tubulin beta-4B chain reviewed Cellular structure TUBB4B Activity '=' 4 uM
O94956 BXGT005343 Solute carrier organic anion transporter family member 2B1 reviewed Transporter SLCO2B1 Inhibition '=' 24 %
Q9BUF5 BXGT020135 Tubulin beta-6 chain reviewed Cellular structure TUBB6 IC50 '=' 5400 nM
Q9BVA1 BXGT020142 Tubulin beta-2B chain reviewed - TUBB2B IC50 '=' 5400 nM
Q13885 BXGT013400 Tubulin beta-2A chain reviewed Cellular structure TUBB2A IC50 '=' 5400 nM
Q6PEY2 BXGT016465 Tubulin alpha-3E chain reviewed Cellular structure TUBA3E IC50 '=' 5400 nM
Q9BQE3 BXGT020109 Tubulin alpha-1C chain reviewed Cellular structure TUBA1C IC50 '=' 5400 nM
P68363 BXGT011594 Tubulin alpha-1B chain reviewed Cellular structure TUBA1B IC50 '=' 5400 nM
P07437 BXGT006624 Tubulin beta chain reviewed Cellular structure TUBB IC50 '=' 5400 nM
Q3ZCM7 BXGT014551 Tubulin beta-8 chain reviewed - TUBB8 IC50 '=' 5400 nM
P04350 BXGT006193 Tubulin beta-4A chain reviewed Cellular structure TUBB4A IC50 '=' 5400 nM
Q71U36 BXGT016705 Tubulin alpha-1A chain reviewed Cellular structure TUBA1A IC50 '=' 5400 nM
Q13509 BXGT013366 Tubulin beta-3 chain reviewed Cellular structure TUBB3 IC50 '=' 5400 nM
P68366 BXGT011595 Tubulin alpha-4A chain reviewed Cellular structure TUBA4A IC50 '=' 5400 nM
P0DPH7 BXGT007527 Tubulin alpha-3C chain reviewed - TUBA3C IC50 '=' 5400 nM
Q9H4B7 BXGT020475 Tubulin beta-1 chain reviewed Cellular structure TUBB1 IC50 '=' 5400 nM
P68371 BXGT011597 Tubulin beta-4B chain reviewed Cellular structure TUBB4B IC50 '=' 5400 nM
P08588 BXGT006795 Beta-1 adrenergic receptor reviewed G-protein coupled receptor ADRB1 IC50 - - -
Q9BUF5 BXGT020135 Tubulin beta-6 chain reviewed Cellular structure TUBB6 IC50 '=' 360 nM
Q9BVA1 BXGT020142 Tubulin beta-2B chain reviewed - TUBB2B IC50 '=' 360 nM
Q13885 BXGT013400 Tubulin beta-2A chain reviewed Cellular structure TUBB2A IC50 '=' 360 nM
Q6PEY2 BXGT016465 Tubulin alpha-3E chain reviewed Cellular structure TUBA3E IC50 '=' 360 nM
Q9BQE3 BXGT020109 Tubulin alpha-1C chain reviewed Cellular structure TUBA1C IC50 '=' 360 nM
P68363 BXGT011594 Tubulin alpha-1B chain reviewed Cellular structure TUBA1B IC50 '=' 360 nM
P07437 BXGT006624 Tubulin beta chain reviewed Cellular structure TUBB IC50 '=' 360 nM
Q3ZCM7 BXGT014551 Tubulin beta-8 chain reviewed - TUBB8 IC50 '=' 360 nM
P04350 BXGT006193 Tubulin beta-4A chain reviewed Cellular structure TUBB4A IC50 '=' 360 nM
Q71U36 BXGT016705 Tubulin alpha-1A chain reviewed Cellular structure TUBA1A IC50 '=' 360 nM
Q13509 BXGT013366 Tubulin beta-3 chain reviewed Cellular structure TUBB3 IC50 '=' 360 nM
P68366 BXGT011595 Tubulin alpha-4A chain reviewed Cellular structure TUBA4A IC50 '=' 360 nM
P0DPH7 BXGT007527 Tubulin alpha-3C chain reviewed - TUBA3C IC50 '=' 360 nM
Q9H4B7 BXGT020475 Tubulin beta-1 chain reviewed Cellular structure TUBB1 IC50 '=' 360 nM
P68371 BXGT011597 Tubulin beta-4B chain reviewed Cellular structure TUBB4B IC50 '=' 360 nM
P84022 BXGT012027 Mothers against decapentaplegic homolog 3 reviewed Transcription factor SMAD3 Potency - 1122 nM
O75496 BXGT005132 Geminin reviewed - GMNN Potency - 42 nM
Q9BUF5 BXGT020135 Tubulin beta-6 chain reviewed Cellular structure TUBB6 Activity '=' 6 uM
Q9BVA1 BXGT020142 Tubulin beta-2B chain reviewed - TUBB2B Activity '=' 6 uM
Q13885 BXGT013400 Tubulin beta-2A chain reviewed Cellular structure TUBB2A Activity '=' 6 uM
Q6PEY2 BXGT016465 Tubulin alpha-3E chain reviewed Cellular structure TUBA3E Activity '=' 6 uM
Q9BQE3 BXGT020109 Tubulin alpha-1C chain reviewed Cellular structure TUBA1C Activity '=' 6 uM
P68363 BXGT011594 Tubulin alpha-1B chain reviewed Cellular structure TUBA1B Activity '=' 6 uM
P07437 BXGT006624 Tubulin beta chain reviewed Cellular structure TUBB Activity '=' 6 uM
Q3ZCM7 BXGT014551 Tubulin beta-8 chain reviewed - TUBB8 Activity '=' 6 uM
P04350 BXGT006193 Tubulin beta-4A chain reviewed Cellular structure TUBB4A Activity '=' 6 uM
Q71U36 BXGT016705 Tubulin alpha-1A chain reviewed Cellular structure TUBA1A Activity '=' 6 uM
Q13509 BXGT013366 Tubulin beta-3 chain reviewed Cellular structure TUBB3 Activity '=' 6 uM
P68366 BXGT011595 Tubulin alpha-4A chain reviewed Cellular structure TUBA4A Activity '=' 6 uM
P0DPH7 BXGT007527 Tubulin alpha-3C chain reviewed - TUBA3C Activity '=' 6 uM
Q9H4B7 BXGT020475 Tubulin beta-1 chain reviewed Cellular structure TUBB1 Activity '=' 6 uM
P68371 BXGT011597 Tubulin beta-4B chain reviewed Cellular structure TUBB4B Activity '=' 6 uM
O15439 BXGT004169 Multidrug resistance-associated protein 4 reviewed Transporter ABCC4 IC50 '=' 133000 nM
Q16236 BXGT013624 Nuclear factor erythroid 2-related factor 2 reviewed Enzyme NFE2L2 Potency - 153 nM
P10145 BXGT007542 Interleukin-8 reviewed Signaling CXCL8 Potency - 47 nM
Q9BUF5 BXGT020135 Tubulin beta-6 chain reviewed Cellular structure TUBB6 TIME '=' 0 hr
Q9BVA1 BXGT020142 Tubulin beta-2B chain reviewed - TUBB2B TIME '=' 0 hr
Q13885 BXGT013400 Tubulin beta-2A chain reviewed Cellular structure TUBB2A TIME '=' 0 hr
Q6PEY2 BXGT016465 Tubulin alpha-3E chain reviewed Cellular structure TUBA3E TIME '=' 0 hr
Q9BQE3 BXGT020109 Tubulin alpha-1C chain reviewed Cellular structure TUBA1C TIME '=' 0 hr
P68363 BXGT011594 Tubulin alpha-1B chain reviewed Cellular structure TUBA1B TIME '=' 0 hr
P07437 BXGT006624 Tubulin beta chain reviewed Cellular structure TUBB TIME '=' 0 hr
Q3ZCM7 BXGT014551 Tubulin beta-8 chain reviewed - TUBB8 TIME '=' 0 hr
P04350 BXGT006193 Tubulin beta-4A chain reviewed Cellular structure TUBB4A TIME '=' 0 hr
Q71U36 BXGT016705 Tubulin alpha-1A chain reviewed Cellular structure TUBA1A TIME '=' 0 hr
Q13509 BXGT013366 Tubulin beta-3 chain reviewed Cellular structure TUBB3 TIME '=' 0 hr
P68366 BXGT011595 Tubulin alpha-4A chain reviewed Cellular structure TUBA4A TIME '=' 0 hr
P0DPH7 BXGT007527 Tubulin alpha-3C chain reviewed - TUBA3C TIME '=' 0 hr
Q9H4B7 BXGT020475 Tubulin beta-1 chain reviewed Cellular structure TUBB1 TIME '=' 0 hr
P68371 BXGT011597 Tubulin beta-4B chain reviewed Cellular structure TUBB4B TIME '=' 0 hr
Q9BUF5 BXGT020135 Tubulin beta-6 chain reviewed Cellular structure TUBB6 TIME '=' 0 hr
Q9BVA1 BXGT020142 Tubulin beta-2B chain reviewed - TUBB2B TIME '=' 0 hr
Q13885 BXGT013400 Tubulin beta-2A chain reviewed Cellular structure TUBB2A TIME '=' 0 hr
Q6PEY2 BXGT016465 Tubulin alpha-3E chain reviewed Cellular structure TUBA3E TIME '=' 0 hr
Q9BQE3 BXGT020109 Tubulin alpha-1C chain reviewed Cellular structure TUBA1C TIME '=' 0 hr
P68363 BXGT011594 Tubulin alpha-1B chain reviewed Cellular structure TUBA1B TIME '=' 0 hr
P07437 BXGT006624 Tubulin beta chain reviewed Cellular structure TUBB TIME '=' 0 hr
Q3ZCM7 BXGT014551 Tubulin beta-8 chain reviewed - TUBB8 TIME '=' 0 hr
P04350 BXGT006193 Tubulin beta-4A chain reviewed Cellular structure TUBB4A TIME '=' 0 hr
Q71U36 BXGT016705 Tubulin alpha-1A chain reviewed Cellular structure TUBA1A TIME '=' 0 hr
Q13509 BXGT013366 Tubulin beta-3 chain reviewed Cellular structure TUBB3 TIME '=' 0 hr
P68366 BXGT011595 Tubulin alpha-4A chain reviewed Cellular structure TUBA4A TIME '=' 0 hr
P0DPH7 BXGT007527 Tubulin alpha-3C chain reviewed - TUBA3C TIME '=' 0 hr
Q9H4B7 BXGT020475 Tubulin beta-1 chain reviewed Cellular structure TUBB1 TIME '=' 0 hr
P68371 BXGT011597 Tubulin beta-4B chain reviewed Cellular structure TUBB4B TIME '=' 0 hr
P50406 BXGT010796 5-hydroxytryptamine receptor 6 reviewed G-protein coupled receptor HTR6 IC50 - - -
Q12809 BXGT013267 Potassium voltage-gated channel subfamily H member 2 reviewed Ion channel KCNH2 Ki - - -
P29466 BXGT009349 Caspase-1 reviewed Enzyme CASP1 IC50 - - -
P17252 BXGT008294 Protein kinase C alpha type reviewed Kinase PRKCA Ki - - -
P10145 BXGT007542 Interleukin-8 reviewed Signaling CXCL8 Potency - 53 nM
P37231 BXGT009972 Peroxisome proliferator-activated receptor gamma reviewed Nuclear receptor PPARG Potency - 70 nM
P08183 BXGT006741 ATP-dependent translocase ABCB1 reviewed Transporter ABCB1 % maximum response '=' 0 %
P29466 BXGT009349 Caspase-1 reviewed Enzyme CASP1 Potency '=' 39810 nM
Q9BUF5 BXGT020135 Tubulin beta-6 chain reviewed Cellular structure TUBB6 Activity '=' 2 /min
Q9BVA1 BXGT020142 Tubulin beta-2B chain reviewed - TUBB2B Activity '=' 2 /min
Q13885 BXGT013400 Tubulin beta-2A chain reviewed Cellular structure TUBB2A Activity '=' 2 /min
Q6PEY2 BXGT016465 Tubulin alpha-3E chain reviewed Cellular structure TUBA3E Activity '=' 2 /min
Q9BQE3 BXGT020109 Tubulin alpha-1C chain reviewed Cellular structure TUBA1C Activity '=' 2 /min
P68363 BXGT011594 Tubulin alpha-1B chain reviewed Cellular structure TUBA1B Activity '=' 2 /min
P07437 BXGT006624 Tubulin beta chain reviewed Cellular structure TUBB Activity '=' 2 /min
Q3ZCM7 BXGT014551 Tubulin beta-8 chain reviewed - TUBB8 Activity '=' 2 /min
P04350 BXGT006193 Tubulin beta-4A chain reviewed Cellular structure TUBB4A Activity '=' 2 /min
Q71U36 BXGT016705 Tubulin alpha-1A chain reviewed Cellular structure TUBA1A Activity '=' 2 /min
Q13509 BXGT013366 Tubulin beta-3 chain reviewed Cellular structure TUBB3 Activity '=' 2 /min
P68366 BXGT011595 Tubulin alpha-4A chain reviewed Cellular structure TUBA4A Activity '=' 2 /min
P0DPH7 BXGT007527 Tubulin alpha-3C chain reviewed - TUBA3C Activity '=' 2 /min
Q9H4B7 BXGT020475 Tubulin beta-1 chain reviewed Cellular structure TUBB1 Activity '=' 2 /min
P68371 BXGT011597 Tubulin beta-4B chain reviewed Cellular structure TUBB4B Activity '=' 2 /min
Q9BUF5 BXGT020135 Tubulin beta-6 chain reviewed Cellular structure TUBB6 Activity '=' 1 /min
Q9BVA1 BXGT020142 Tubulin beta-2B chain reviewed - TUBB2B Activity '=' 1 /min
Q13885 BXGT013400 Tubulin beta-2A chain reviewed Cellular structure TUBB2A Activity '=' 1 /min
Q6PEY2 BXGT016465 Tubulin alpha-3E chain reviewed Cellular structure TUBA3E Activity '=' 1 /min
Q9BQE3 BXGT020109 Tubulin alpha-1C chain reviewed Cellular structure TUBA1C Activity '=' 1 /min
P68363 BXGT011594 Tubulin alpha-1B chain reviewed Cellular structure TUBA1B Activity '=' 1 /min
P07437 BXGT006624 Tubulin beta chain reviewed Cellular structure TUBB Activity '=' 1 /min
Q3ZCM7 BXGT014551 Tubulin beta-8 chain reviewed - TUBB8 Activity '=' 1 /min
P04350 BXGT006193 Tubulin beta-4A chain reviewed Cellular structure TUBB4A Activity '=' 1 /min
Q71U36 BXGT016705 Tubulin alpha-1A chain reviewed Cellular structure TUBA1A Activity '=' 1 /min
Q13509 BXGT013366 Tubulin beta-3 chain reviewed Cellular structure TUBB3 Activity '=' 1 /min
P68366 BXGT011595 Tubulin alpha-4A chain reviewed Cellular structure TUBA4A Activity '=' 1 /min
P0DPH7 BXGT007527 Tubulin alpha-3C chain reviewed - TUBA3C Activity '=' 1 /min
Q9H4B7 BXGT020475 Tubulin beta-1 chain reviewed Cellular structure TUBB1 Activity '=' 1 /min
P68371 BXGT011597 Tubulin beta-4B chain reviewed Cellular structure TUBB4B Activity '=' 1 /min
Q9BUF5 BXGT020135 Tubulin beta-6 chain reviewed Cellular structure TUBB6 Activity '=' 24 uM
Q9BVA1 BXGT020142 Tubulin beta-2B chain reviewed - TUBB2B Activity '=' 24 uM
Q13885 BXGT013400 Tubulin beta-2A chain reviewed Cellular structure TUBB2A Activity '=' 24 uM
Q6PEY2 BXGT016465 Tubulin alpha-3E chain reviewed Cellular structure TUBA3E Activity '=' 24 uM
Q9BQE3 BXGT020109 Tubulin alpha-1C chain reviewed Cellular structure TUBA1C Activity '=' 24 uM
P68363 BXGT011594 Tubulin alpha-1B chain reviewed Cellular structure TUBA1B Activity '=' 24 uM
P07437 BXGT006624 Tubulin beta chain reviewed Cellular structure TUBB Activity '=' 24 uM
Q3ZCM7 BXGT014551 Tubulin beta-8 chain reviewed - TUBB8 Activity '=' 24 uM
P04350 BXGT006193 Tubulin beta-4A chain reviewed Cellular structure TUBB4A Activity '=' 24 uM
Q71U36 BXGT016705 Tubulin alpha-1A chain reviewed Cellular structure TUBA1A Activity '=' 24 uM
Q13509 BXGT013366 Tubulin beta-3 chain reviewed Cellular structure TUBB3 Activity '=' 24 uM
P68366 BXGT011595 Tubulin alpha-4A chain reviewed Cellular structure TUBA4A Activity '=' 24 uM
P0DPH7 BXGT007527 Tubulin alpha-3C chain reviewed - TUBA3C Activity '=' 24 uM
Q9H4B7 BXGT020475 Tubulin beta-1 chain reviewed Cellular structure TUBB1 Activity '=' 24 uM
P68371 BXGT011597 Tubulin beta-4B chain reviewed Cellular structure TUBB4B Activity '=' 24 uM
P27695 BXGT009199 DNA-(apurinic or apyrimidinic site) lyase reviewed - APEX1 Potency - 70794 nM
P33261 BXGT009707 Cytochrome P450 2C19 reviewed - CYP2C19 IC50 - - -
P11712 BXGT007738 Cytochrome P450 2C9 reviewed - CYP2C9 IC50 - - -
P35462 BXGT009835 D(3) dopamine receptor reviewed G-protein coupled receptor DRD3 Ki - - -
O75496 BXGT005132 Geminin reviewed - GMNN Potency '=' 39 nM
P02550 BXGT005891 Tubulin alpha-1A chain reviewed - TUBA1A IC50 '=' 2680 nM
P02554 BXGT005892 Tubulin beta chain reviewed - IC50 '=' 2680 nM
P51151 BXGT010837 Ras-related protein Rab-9A reviewed - RAB9A Potency '=' 1995 nM
O89049 BXGT005293 Thioredoxin reductase 1, cytoplasmic reviewed - Txnrd1 Potency - 9466 nM
O75751 BXGT005150 Solute carrier family 22 member 3 reviewed Transporter SLC22A3 Ki '=' 120 nM
Q9NUW8 BXGT021219 Tyrosyl-DNA phosphodiesterase 1 reviewed Enzyme TDP1 Potency - 16 nM
Q9BUF5 BXGT020135 Tubulin beta-6 chain reviewed Cellular structure TUBB6 Ki '=' 2400 nM
Q9BVA1 BXGT020142 Tubulin beta-2B chain reviewed - TUBB2B Ki '=' 2400 nM
Q13885 BXGT013400 Tubulin beta-2A chain reviewed Cellular structure TUBB2A Ki '=' 2400 nM
Q6PEY2 BXGT016465 Tubulin alpha-3E chain reviewed Cellular structure TUBA3E Ki '=' 2400 nM
Q9BQE3 BXGT020109 Tubulin alpha-1C chain reviewed Cellular structure TUBA1C Ki '=' 2400 nM
P68363 BXGT011594 Tubulin alpha-1B chain reviewed Cellular structure TUBA1B Ki '=' 2400 nM
P07437 BXGT006624 Tubulin beta chain reviewed Cellular structure TUBB Ki '=' 2400 nM
Q3ZCM7 BXGT014551 Tubulin beta-8 chain reviewed - TUBB8 Ki '=' 2400 nM
P04350 BXGT006193 Tubulin beta-4A chain reviewed Cellular structure TUBB4A Ki '=' 2400 nM
Q71U36 BXGT016705 Tubulin alpha-1A chain reviewed Cellular structure TUBA1A Ki '=' 2400 nM
Q13509 BXGT013366 Tubulin beta-3 chain reviewed Cellular structure TUBB3 Ki '=' 2400 nM
P68366 BXGT011595 Tubulin alpha-4A chain reviewed Cellular structure TUBA4A Ki '=' 2400 nM
P0DPH7 BXGT007527 Tubulin alpha-3C chain reviewed - TUBA3C Ki '=' 2400 nM
Q9H4B7 BXGT020475 Tubulin beta-1 chain reviewed Cellular structure TUBB1 Ki '=' 2400 nM
P68371 BXGT011597 Tubulin beta-4B chain reviewed Cellular structure TUBB4B Ki '=' 2400 nM
P31645 BXGT009558 Sodium-dependent serotonin transporter reviewed Transporter SLC6A4 Ki - - -
P21447 BXGT008651 ATP-dependent translocase ABCB1 reviewed - Abcb1a Activity - - -
Q9BUF5 BXGT020135 Tubulin beta-6 chain reviewed Cellular structure TUBB6 Activity '=' 29 um/min
Q9BVA1 BXGT020142 Tubulin beta-2B chain reviewed - TUBB2B Activity '=' 29 um/min
Q13885 BXGT013400 Tubulin beta-2A chain reviewed Cellular structure TUBB2A Activity '=' 29 um/min
Q6PEY2 BXGT016465 Tubulin alpha-3E chain reviewed Cellular structure TUBA3E Activity '=' 29 um/min
Q9BQE3 BXGT020109 Tubulin alpha-1C chain reviewed Cellular structure TUBA1C Activity '=' 29 um/min
P68363 BXGT011594 Tubulin alpha-1B chain reviewed Cellular structure TUBA1B Activity '=' 29 um/min
P07437 BXGT006624 Tubulin beta chain reviewed Cellular structure TUBB Activity '=' 29 um/min
Q3ZCM7 BXGT014551 Tubulin beta-8 chain reviewed - TUBB8 Activity '=' 29 um/min
P04350 BXGT006193 Tubulin beta-4A chain reviewed Cellular structure TUBB4A Activity '=' 29 um/min
Q71U36 BXGT016705 Tubulin alpha-1A chain reviewed Cellular structure TUBA1A Activity '=' 29 um/min
Q13509 BXGT013366 Tubulin beta-3 chain reviewed Cellular structure TUBB3 Activity '=' 29 um/min
P68366 BXGT011595 Tubulin alpha-4A chain reviewed Cellular structure TUBA4A Activity '=' 29 um/min
P0DPH7 BXGT007527 Tubulin alpha-3C chain reviewed - TUBA3C Activity '=' 29 um/min
Q9H4B7 BXGT020475 Tubulin beta-1 chain reviewed Cellular structure TUBB1 Activity '=' 29 um/min
P68371 BXGT011597 Tubulin beta-4B chain reviewed Cellular structure TUBB4B Activity '=' 29 um/min
Q9NPD5 BXGT021151 Solute carrier organic anion transporter family member 1B3 reviewed Transporter SLCO1B3 Inhibition '=' 101 %
Q9BUF5 BXGT020135 Tubulin beta-6 chain reviewed Cellular structure TUBB6 Inhibition '=' 64 %
Q9BVA1 BXGT020142 Tubulin beta-2B chain reviewed - TUBB2B Inhibition '=' 64 %
Q13885 BXGT013400 Tubulin beta-2A chain reviewed Cellular structure TUBB2A Inhibition '=' 64 %
Q6PEY2 BXGT016465 Tubulin alpha-3E chain reviewed Cellular structure TUBA3E Inhibition '=' 64 %
Q9BQE3 BXGT020109 Tubulin alpha-1C chain reviewed Cellular structure TUBA1C Inhibition '=' 64 %
P68363 BXGT011594 Tubulin alpha-1B chain reviewed Cellular structure TUBA1B Inhibition '=' 64 %
P07437 BXGT006624 Tubulin beta chain reviewed Cellular structure TUBB Inhibition '=' 64 %
Q3ZCM7 BXGT014551 Tubulin beta-8 chain reviewed - TUBB8 Inhibition '=' 64 %
P04350 BXGT006193 Tubulin beta-4A chain reviewed Cellular structure TUBB4A Inhibition '=' 64 %
Q71U36 BXGT016705 Tubulin alpha-1A chain reviewed Cellular structure TUBA1A Inhibition '=' 64 %
Q13509 BXGT013366 Tubulin beta-3 chain reviewed Cellular structure TUBB3 Inhibition '=' 64 %
P68366 BXGT011595 Tubulin alpha-4A chain reviewed Cellular structure TUBA4A Inhibition '=' 64 %
P0DPH7 BXGT007527 Tubulin alpha-3C chain reviewed - TUBA3C Inhibition '=' 64 %
Q9H4B7 BXGT020475 Tubulin beta-1 chain reviewed Cellular structure TUBB1 Inhibition '=' 64 %
P68371 BXGT011597 Tubulin beta-4B chain reviewed Cellular structure TUBB4B Inhibition '=' 64 %
O89049 BXGT005293 Thioredoxin reductase 1, cytoplasmic reviewed - Txnrd1 Potency - 29934 nM
Q6B856 BXGT016212 Tubulin beta-2B chain reviewed - TUBB2B IC50 '=' 11200000 nM
Q9BUF5 BXGT020135 Tubulin beta-6 chain reviewed Cellular structure TUBB6 Activity '>' 15 uM
Q9BVA1 BXGT020142 Tubulin beta-2B chain reviewed - TUBB2B Activity '>' 15 uM
Q13885 BXGT013400 Tubulin beta-2A chain reviewed Cellular structure TUBB2A Activity '>' 15 uM
Q6PEY2 BXGT016465 Tubulin alpha-3E chain reviewed Cellular structure TUBA3E Activity '>' 15 uM
Q9BQE3 BXGT020109 Tubulin alpha-1C chain reviewed Cellular structure TUBA1C Activity '>' 15 uM
P68363 BXGT011594 Tubulin alpha-1B chain reviewed Cellular structure TUBA1B Activity '>' 15 uM
P07437 BXGT006624 Tubulin beta chain reviewed Cellular structure TUBB Activity '>' 15 uM
Q3ZCM7 BXGT014551 Tubulin beta-8 chain reviewed - TUBB8 Activity '>' 15 uM
P04350 BXGT006193 Tubulin beta-4A chain reviewed Cellular structure TUBB4A Activity '>' 15 uM
Q71U36 BXGT016705 Tubulin alpha-1A chain reviewed Cellular structure TUBA1A Activity '>' 15 uM
Q13509 BXGT013366 Tubulin beta-3 chain reviewed Cellular structure TUBB3 Activity '>' 15 uM
P68366 BXGT011595 Tubulin alpha-4A chain reviewed Cellular structure TUBA4A Activity '>' 15 uM
P0DPH7 BXGT007527 Tubulin alpha-3C chain reviewed - TUBA3C Activity '>' 15 uM
Q9H4B7 BXGT020475 Tubulin beta-1 chain reviewed Cellular structure TUBB1 Activity '>' 15 uM
P68371 BXGT011597 Tubulin beta-4B chain reviewed Cellular structure TUBB4B Activity '>' 15 uM
Q13547 BXGT013373 Histone deacetylase 1 reviewed Epigenetic regulator HDAC1 IC50 '>' 20 ug.mL-1
Q9BUF5 BXGT020135 Tubulin beta-6 chain reviewed Cellular structure TUBB6 Inhibition '=' 32 %
Q9BVA1 BXGT020142 Tubulin beta-2B chain reviewed - TUBB2B Inhibition '=' 32 %
Q13885 BXGT013400 Tubulin beta-2A chain reviewed Cellular structure TUBB2A Inhibition '=' 32 %
Q6PEY2 BXGT016465 Tubulin alpha-3E chain reviewed Cellular structure TUBA3E Inhibition '=' 32 %
Q9BQE3 BXGT020109 Tubulin alpha-1C chain reviewed Cellular structure TUBA1C Inhibition '=' 32 %
P68363 BXGT011594 Tubulin alpha-1B chain reviewed Cellular structure TUBA1B Inhibition '=' 32 %
P07437 BXGT006624 Tubulin beta chain reviewed Cellular structure TUBB Inhibition '=' 32 %
Q3ZCM7 BXGT014551 Tubulin beta-8 chain reviewed - TUBB8 Inhibition '=' 32 %
P04350 BXGT006193 Tubulin beta-4A chain reviewed Cellular structure TUBB4A Inhibition '=' 32 %
Q71U36 BXGT016705 Tubulin alpha-1A chain reviewed Cellular structure TUBA1A Inhibition '=' 32 %
Q13509 BXGT013366 Tubulin beta-3 chain reviewed Cellular structure TUBB3 Inhibition '=' 32 %
P68366 BXGT011595 Tubulin alpha-4A chain reviewed Cellular structure TUBA4A Inhibition '=' 32 %
P0DPH7 BXGT007527 Tubulin alpha-3C chain reviewed - TUBA3C Inhibition '=' 32 %
Q9H4B7 BXGT020475 Tubulin beta-1 chain reviewed Cellular structure TUBB1 Inhibition '=' 32 %
P68371 BXGT011597 Tubulin beta-4B chain reviewed Cellular structure TUBB4B Inhibition '=' 32 %
Q862F3 BXGT017581 Similar to alpha-tubulin isoform 1 unreviewed - Inhibition '=' 40 %
Q862L2 BXGT017582 Similar to alpha-tubulin isoform 1 unreviewed - Inhibition '=' 40 %
Q6B856 BXGT016212 Tubulin beta-2B chain reviewed - TUBB2B Inhibition '=' 40 %
Q862F3 BXGT017581 Similar to alpha-tubulin isoform 1 unreviewed - IC50 '=' 7600 nM
Q862L2 BXGT017582 Similar to alpha-tubulin isoform 1 unreviewed - IC50 '=' 7600 nM
Q6B856 BXGT016212 Tubulin beta-2B chain reviewed - TUBB2B IC50 '=' 7600 nM
P11712 BXGT007738 Cytochrome P450 2C9 reviewed - CYP2C9 Inhibition '=' 11 %
P10635 BXGT007595 Cytochrome P450 2D6 reviewed - CYP2D6 Inhibition '=' 7 %
Q9BUF5 BXGT020135 Tubulin beta-6 chain reviewed Cellular structure TUBB6 Activity '=' 3 uM
Q9BVA1 BXGT020142 Tubulin beta-2B chain reviewed - TUBB2B Activity '=' 3 uM
Q13885 BXGT013400 Tubulin beta-2A chain reviewed Cellular structure TUBB2A Activity '=' 3 uM
Q6PEY2 BXGT016465 Tubulin alpha-3E chain reviewed Cellular structure TUBA3E Activity '=' 3 uM
Q9BQE3 BXGT020109 Tubulin alpha-1C chain reviewed Cellular structure TUBA1C Activity '=' 3 uM
P68363 BXGT011594 Tubulin alpha-1B chain reviewed Cellular structure TUBA1B Activity '=' 3 uM
P07437 BXGT006624 Tubulin beta chain reviewed Cellular structure TUBB Activity '=' 3 uM
Q3ZCM7 BXGT014551 Tubulin beta-8 chain reviewed - TUBB8 Activity '=' 3 uM
P04350 BXGT006193 Tubulin beta-4A chain reviewed Cellular structure TUBB4A Activity '=' 3 uM
Q71U36 BXGT016705 Tubulin alpha-1A chain reviewed Cellular structure TUBA1A Activity '=' 3 uM
Q13509 BXGT013366 Tubulin beta-3 chain reviewed Cellular structure TUBB3 Activity '=' 3 uM
P68366 BXGT011595 Tubulin alpha-4A chain reviewed Cellular structure TUBA4A Activity '=' 3 uM
P0DPH7 BXGT007527 Tubulin alpha-3C chain reviewed - TUBA3C Activity '=' 3 uM
Q9H4B7 BXGT020475 Tubulin beta-1 chain reviewed Cellular structure TUBB1 Activity '=' 3 uM
P68371 BXGT011597 Tubulin beta-4B chain reviewed Cellular structure TUBB4B Activity '=' 3 uM
Q9BUF5 BXGT020135 Tubulin beta-6 chain reviewed Cellular structure TUBB6 Activity '=' 13 uM
Q9BVA1 BXGT020142 Tubulin beta-2B chain reviewed - TUBB2B Activity '=' 13 uM
Q13885 BXGT013400 Tubulin beta-2A chain reviewed Cellular structure TUBB2A Activity '=' 13 uM
Q6PEY2 BXGT016465 Tubulin alpha-3E chain reviewed Cellular structure TUBA3E Activity '=' 13 uM
Q9BQE3 BXGT020109 Tubulin alpha-1C chain reviewed Cellular structure TUBA1C Activity '=' 13 uM
P68363 BXGT011594 Tubulin alpha-1B chain reviewed Cellular structure TUBA1B Activity '=' 13 uM
P07437 BXGT006624 Tubulin beta chain reviewed Cellular structure TUBB Activity '=' 13 uM
Q3ZCM7 BXGT014551 Tubulin beta-8 chain reviewed - TUBB8 Activity '=' 13 uM
P04350 BXGT006193 Tubulin beta-4A chain reviewed Cellular structure TUBB4A Activity '=' 13 uM
Q71U36 BXGT016705 Tubulin alpha-1A chain reviewed Cellular structure TUBA1A Activity '=' 13 uM
Q13509 BXGT013366 Tubulin beta-3 chain reviewed Cellular structure TUBB3 Activity '=' 13 uM
P68366 BXGT011595 Tubulin alpha-4A chain reviewed Cellular structure TUBA4A Activity '=' 13 uM
P0DPH7 BXGT007527 Tubulin alpha-3C chain reviewed - TUBA3C Activity '=' 13 uM
Q9H4B7 BXGT020475 Tubulin beta-1 chain reviewed Cellular structure TUBB1 Activity '=' 13 uM
P68371 BXGT011597 Tubulin beta-4B chain reviewed Cellular structure TUBB4B Activity '=' 13 uM
P05177 BXGT006336 Cytochrome P450 1A2 reviewed Enzyme CYP1A2 Inhibition '=' 12 %
Q923J1 BXGT019344 Transient receptor potential cation channel subfamily M member 7 reviewed - Trpm7 Inhibition - - -
Q9BUF5 BXGT020135 Tubulin beta-6 chain reviewed Cellular structure TUBB6 Activity '=' 72 %
Q9BVA1 BXGT020142 Tubulin beta-2B chain reviewed - TUBB2B Activity '=' 72 %
Q13885 BXGT013400 Tubulin beta-2A chain reviewed Cellular structure TUBB2A Activity '=' 72 %
Q6PEY2 BXGT016465 Tubulin alpha-3E chain reviewed Cellular structure TUBA3E Activity '=' 72 %
Q9BQE3 BXGT020109 Tubulin alpha-1C chain reviewed Cellular structure TUBA1C Activity '=' 72 %
P68363 BXGT011594 Tubulin alpha-1B chain reviewed Cellular structure TUBA1B Activity '=' 72 %
P07437 BXGT006624 Tubulin beta chain reviewed Cellular structure TUBB Activity '=' 72 %
Q3ZCM7 BXGT014551 Tubulin beta-8 chain reviewed - TUBB8 Activity '=' 72 %
P04350 BXGT006193 Tubulin beta-4A chain reviewed Cellular structure TUBB4A Activity '=' 72 %
Q71U36 BXGT016705 Tubulin alpha-1A chain reviewed Cellular structure TUBA1A Activity '=' 72 %
Q13509 BXGT013366 Tubulin beta-3 chain reviewed Cellular structure TUBB3 Activity '=' 72 %
P68366 BXGT011595 Tubulin alpha-4A chain reviewed Cellular structure TUBA4A Activity '=' 72 %
P0DPH7 BXGT007527 Tubulin alpha-3C chain reviewed - TUBA3C Activity '=' 72 %
Q9H4B7 BXGT020475 Tubulin beta-1 chain reviewed Cellular structure TUBB1 Activity '=' 72 %
P68371 BXGT011597 Tubulin beta-4B chain reviewed Cellular structure TUBB4B Activity '=' 72 %
P08684 BXGT006812 Cytochrome P450 3A4 reviewed Enzyme CYP3A4 Inhibition '=' 9 %
Q9BUF5 BXGT020135 Tubulin beta-6 chain reviewed Cellular structure TUBB6 Activity '=' 25 %
Q9BVA1 BXGT020142 Tubulin beta-2B chain reviewed - TUBB2B Activity '=' 25 %
Q13885 BXGT013400 Tubulin beta-2A chain reviewed Cellular structure TUBB2A Activity '=' 25 %
Q6PEY2 BXGT016465 Tubulin alpha-3E chain reviewed Cellular structure TUBA3E Activity '=' 25 %
Q9BQE3 BXGT020109 Tubulin alpha-1C chain reviewed Cellular structure TUBA1C Activity '=' 25 %
P68363 BXGT011594 Tubulin alpha-1B chain reviewed Cellular structure TUBA1B Activity '=' 25 %
P07437 BXGT006624 Tubulin beta chain reviewed Cellular structure TUBB Activity '=' 25 %
Q3ZCM7 BXGT014551 Tubulin beta-8 chain reviewed - TUBB8 Activity '=' 25 %
P04350 BXGT006193 Tubulin beta-4A chain reviewed Cellular structure TUBB4A Activity '=' 25 %
Q71U36 BXGT016705 Tubulin alpha-1A chain reviewed Cellular structure TUBA1A Activity '=' 25 %
Q13509 BXGT013366 Tubulin beta-3 chain reviewed Cellular structure TUBB3 Activity '=' 25 %
P68366 BXGT011595 Tubulin alpha-4A chain reviewed Cellular structure TUBA4A Activity '=' 25 %
P0DPH7 BXGT007527 Tubulin alpha-3C chain reviewed - TUBA3C Activity '=' 25 %
Q9H4B7 BXGT020475 Tubulin beta-1 chain reviewed Cellular structure TUBB1 Activity '=' 25 %
P68371 BXGT011597 Tubulin beta-4B chain reviewed Cellular structure TUBB4B Activity '=' 25 %
P02550 BXGT005891 Tubulin alpha-1A chain reviewed - TUBA1A IC50 '=' 3790 nM
P02554 BXGT005892 Tubulin beta chain reviewed - IC50 '=' 3790 nM
Q9BUF5 BXGT020135 Tubulin beta-6 chain reviewed Cellular structure TUBB6 Activity '=' 3 uM
Q9BVA1 BXGT020142 Tubulin beta-2B chain reviewed - TUBB2B Activity '=' 3 uM
Q13885 BXGT013400 Tubulin beta-2A chain reviewed Cellular structure TUBB2A Activity '=' 3 uM
Q6PEY2 BXGT016465 Tubulin alpha-3E chain reviewed Cellular structure TUBA3E Activity '=' 3 uM
Q9BQE3 BXGT020109 Tubulin alpha-1C chain reviewed Cellular structure TUBA1C Activity '=' 3 uM
P68363 BXGT011594 Tubulin alpha-1B chain reviewed Cellular structure TUBA1B Activity '=' 3 uM
P07437 BXGT006624 Tubulin beta chain reviewed Cellular structure TUBB Activity '=' 3 uM
Q3ZCM7 BXGT014551 Tubulin beta-8 chain reviewed - TUBB8 Activity '=' 3 uM
P04350 BXGT006193 Tubulin beta-4A chain reviewed Cellular structure TUBB4A Activity '=' 3 uM
Q71U36 BXGT016705 Tubulin alpha-1A chain reviewed Cellular structure TUBA1A Activity '=' 3 uM
Q13509 BXGT013366 Tubulin beta-3 chain reviewed Cellular structure TUBB3 Activity '=' 3 uM
P68366 BXGT011595 Tubulin alpha-4A chain reviewed Cellular structure TUBA4A Activity '=' 3 uM
P0DPH7 BXGT007527 Tubulin alpha-3C chain reviewed - TUBA3C Activity '=' 3 uM
Q9H4B7 BXGT020475 Tubulin beta-1 chain reviewed Cellular structure TUBB1 Activity '=' 3 uM
P68371 BXGT011597 Tubulin beta-4B chain reviewed Cellular structure TUBB4B Activity '=' 3 uM
Q9BUF5 BXGT020135 Tubulin beta-6 chain reviewed Cellular structure TUBB6 Inhibition '=' 97 %
Q9BVA1 BXGT020142 Tubulin beta-2B chain reviewed - TUBB2B Inhibition '=' 97 %
Q13885 BXGT013400 Tubulin beta-2A chain reviewed Cellular structure TUBB2A Inhibition '=' 97 %
Q6PEY2 BXGT016465 Tubulin alpha-3E chain reviewed Cellular structure TUBA3E Inhibition '=' 97 %
Q9BQE3 BXGT020109 Tubulin alpha-1C chain reviewed Cellular structure TUBA1C Inhibition '=' 97 %
P68363 BXGT011594 Tubulin alpha-1B chain reviewed Cellular structure TUBA1B Inhibition '=' 97 %
P07437 BXGT006624 Tubulin beta chain reviewed Cellular structure TUBB Inhibition '=' 97 %
Q3ZCM7 BXGT014551 Tubulin beta-8 chain reviewed - TUBB8 Inhibition '=' 97 %
P04350 BXGT006193 Tubulin beta-4A chain reviewed Cellular structure TUBB4A Inhibition '=' 97 %
Q71U36 BXGT016705 Tubulin alpha-1A chain reviewed Cellular structure TUBA1A Inhibition '=' 97 %
Q13509 BXGT013366 Tubulin beta-3 chain reviewed Cellular structure TUBB3 Inhibition '=' 97 %
P68366 BXGT011595 Tubulin alpha-4A chain reviewed Cellular structure TUBA4A Inhibition '=' 97 %
P0DPH7 BXGT007527 Tubulin alpha-3C chain reviewed - TUBA3C Inhibition '=' 97 %
Q9H4B7 BXGT020475 Tubulin beta-1 chain reviewed Cellular structure TUBB1 Inhibition '=' 97 %
P68371 BXGT011597 Tubulin beta-4B chain reviewed Cellular structure TUBB4B Inhibition '=' 97 %
O15379 BXGT004159 Histone deacetylase 3 reviewed Epigenetic regulator HDAC3 IC50 '>' 20 ug.mL-1
Q92887 BXGT019389 Canalicular multispecific organic anion transporter 1 reviewed Transporter ABCC2 FC '=' 0 -
Q862F3 BXGT017581 Similar to alpha-tubulin isoform 1 unreviewed - IC50 '=' 4100 nM
Q862L2 BXGT017582 Similar to alpha-tubulin isoform 1 unreviewed - IC50 '=' 4100 nM
Q6B856 BXGT016212 Tubulin beta-2B chain reviewed - TUBB2B IC50 '=' 4100 nM
O15438 BXGT004168 Canalicular multispecific organic anion transporter 2 reviewed Transporter ABCC3 IC50 '=' 133000 nM
Q92769 BXGT019370 Histone deacetylase 2 reviewed Epigenetic regulator HDAC2 IC50 '>' 20 ug.mL-1
Q862F3 BXGT017581 Similar to alpha-tubulin isoform 1 unreviewed - Inhibition '=' 87 %
Q862L2 BXGT017582 Similar to alpha-tubulin isoform 1 unreviewed - Inhibition '=' 87 %
Q6B856 BXGT016212 Tubulin beta-2B chain reviewed - TUBB2B Inhibition '=' 87 %
Q9BUF5 BXGT020135 Tubulin beta-6 chain reviewed Cellular structure TUBB6 TIME '=' 0 hr
Q9BVA1 BXGT020142 Tubulin beta-2B chain reviewed - TUBB2B TIME '=' 0 hr
Q13885 BXGT013400 Tubulin beta-2A chain reviewed Cellular structure TUBB2A TIME '=' 0 hr
Q6PEY2 BXGT016465 Tubulin alpha-3E chain reviewed Cellular structure TUBA3E TIME '=' 0 hr
Q9BQE3 BXGT020109 Tubulin alpha-1C chain reviewed Cellular structure TUBA1C TIME '=' 0 hr
P68363 BXGT011594 Tubulin alpha-1B chain reviewed Cellular structure TUBA1B TIME '=' 0 hr
P07437 BXGT006624 Tubulin beta chain reviewed Cellular structure TUBB TIME '=' 0 hr
Q3ZCM7 BXGT014551 Tubulin beta-8 chain reviewed - TUBB8 TIME '=' 0 hr
P04350 BXGT006193 Tubulin beta-4A chain reviewed Cellular structure TUBB4A TIME '=' 0 hr
Q71U36 BXGT016705 Tubulin alpha-1A chain reviewed Cellular structure TUBA1A TIME '=' 0 hr
Q13509 BXGT013366 Tubulin beta-3 chain reviewed Cellular structure TUBB3 TIME '=' 0 hr
P68366 BXGT011595 Tubulin alpha-4A chain reviewed Cellular structure TUBA4A TIME '=' 0 hr
P0DPH7 BXGT007527 Tubulin alpha-3C chain reviewed - TUBA3C TIME '=' 0 hr
Q9H4B7 BXGT020475 Tubulin beta-1 chain reviewed Cellular structure TUBB1 TIME '=' 0 hr
P68371 BXGT011597 Tubulin beta-4B chain reviewed Cellular structure TUBB4B TIME '=' 0 hr
P07437 BXGT006624 Tubulin beta chain reviewed Cellular structure TUBB IC50 '=' 7710 nM
Q92887 BXGT019389 Canalicular multispecific organic anion transporter 1 reviewed Transporter ABCC2 IC50 '=' 133000 nM
Q9BUF5 BXGT020135 Tubulin beta-6 chain reviewed Cellular structure TUBB6 Inhibition '=' 76 %
Q9BVA1 BXGT020142 Tubulin beta-2B chain reviewed - TUBB2B Inhibition '=' 76 %
Q13885 BXGT013400 Tubulin beta-2A chain reviewed Cellular structure TUBB2A Inhibition '=' 76 %
Q6PEY2 BXGT016465 Tubulin alpha-3E chain reviewed Cellular structure TUBA3E Inhibition '=' 76 %
Q9BQE3 BXGT020109 Tubulin alpha-1C chain reviewed Cellular structure TUBA1C Inhibition '=' 76 %
P68363 BXGT011594 Tubulin alpha-1B chain reviewed Cellular structure TUBA1B Inhibition '=' 76 %
P07437 BXGT006624 Tubulin beta chain reviewed Cellular structure TUBB Inhibition '=' 76 %
Q3ZCM7 BXGT014551 Tubulin beta-8 chain reviewed - TUBB8 Inhibition '=' 76 %
P04350 BXGT006193 Tubulin beta-4A chain reviewed Cellular structure TUBB4A Inhibition '=' 76 %
Q71U36 BXGT016705 Tubulin alpha-1A chain reviewed Cellular structure TUBA1A Inhibition '=' 76 %
Q13509 BXGT013366 Tubulin beta-3 chain reviewed Cellular structure TUBB3 Inhibition '=' 76 %
P68366 BXGT011595 Tubulin alpha-4A chain reviewed Cellular structure TUBA4A Inhibition '=' 76 %
P0DPH7 BXGT007527 Tubulin alpha-3C chain reviewed - TUBA3C Inhibition '=' 76 %
Q9H4B7 BXGT020475 Tubulin beta-1 chain reviewed Cellular structure TUBB1 Inhibition '=' 76 %
P68371 BXGT011597 Tubulin beta-4B chain reviewed Cellular structure TUBB4B Inhibition '=' 76 %
P11309 BXGT007685 Serine/threonine-protein kinase pim-1 reviewed Kinase PIM1 IC50 '=' 4300 nM
P02550 BXGT005891 Tubulin alpha-1A chain reviewed - TUBA1A IC50 '=' 6 nM
P02554 BXGT005892 Tubulin beta chain reviewed - IC50 '=' 6 nM
O95342 BXGT005373 Bile salt export pump reviewed Transporter ABCB11 IC50 '=' 298700 nM
O95342 BXGT005373 Bile salt export pump reviewed Transporter ABCB11 IC50 '=' 133000 nM
O75874 BXGT005157 Isocitrate dehydrogenase [NADP] cytoplasmic reviewed - IDH1 Potency - 7 nM
P07437 BXGT006624 Tubulin beta chain reviewed Cellular structure TUBB Inhibition '=' 86 %
Q9BUF5 BXGT020135 Tubulin beta-6 chain reviewed Cellular structure TUBB6 Kd '=' 58 nM
Q9BVA1 BXGT020142 Tubulin beta-2B chain reviewed - TUBB2B Kd '=' 58 nM
Q13885 BXGT013400 Tubulin beta-2A chain reviewed Cellular structure TUBB2A Kd '=' 58 nM
Q6PEY2 BXGT016465 Tubulin alpha-3E chain reviewed Cellular structure TUBA3E Kd '=' 58 nM
Q9BQE3 BXGT020109 Tubulin alpha-1C chain reviewed Cellular structure TUBA1C Kd '=' 58 nM
P68363 BXGT011594 Tubulin alpha-1B chain reviewed Cellular structure TUBA1B Kd '=' 58 nM
P07437 BXGT006624 Tubulin beta chain reviewed Cellular structure TUBB Kd '=' 58 nM
Q3ZCM7 BXGT014551 Tubulin beta-8 chain reviewed - TUBB8 Kd '=' 58 nM
P04350 BXGT006193 Tubulin beta-4A chain reviewed Cellular structure TUBB4A Kd '=' 58 nM
Q71U36 BXGT016705 Tubulin alpha-1A chain reviewed Cellular structure TUBA1A Kd '=' 58 nM
Q13509 BXGT013366 Tubulin beta-3 chain reviewed Cellular structure TUBB3 Kd '=' 58 nM
P68366 BXGT011595 Tubulin alpha-4A chain reviewed Cellular structure TUBA4A Kd '=' 58 nM
P0DPH7 BXGT007527 Tubulin alpha-3C chain reviewed - TUBA3C Kd '=' 58 nM
Q9H4B7 BXGT020475 Tubulin beta-1 chain reviewed Cellular structure TUBB1 Kd '=' 58 nM
P68371 BXGT011597 Tubulin beta-4B chain reviewed Cellular structure TUBB4B Kd '=' 58 nM
P07437 BXGT006624 Tubulin beta chain reviewed Cellular structure TUBB Activity - - -
Q9BUF5 BXGT020135 Tubulin beta-6 chain reviewed Cellular structure TUBB6 TIME '=' 0 hr
Q9BVA1 BXGT020142 Tubulin beta-2B chain reviewed - TUBB2B TIME '=' 0 hr
Q13885 BXGT013400 Tubulin beta-2A chain reviewed Cellular structure TUBB2A TIME '=' 0 hr
Q6PEY2 BXGT016465 Tubulin alpha-3E chain reviewed Cellular structure TUBA3E TIME '=' 0 hr
Q9BQE3 BXGT020109 Tubulin alpha-1C chain reviewed Cellular structure TUBA1C TIME '=' 0 hr
P68363 BXGT011594 Tubulin alpha-1B chain reviewed Cellular structure TUBA1B TIME '=' 0 hr
P07437 BXGT006624 Tubulin beta chain reviewed Cellular structure TUBB TIME '=' 0 hr
Q3ZCM7 BXGT014551 Tubulin beta-8 chain reviewed - TUBB8 TIME '=' 0 hr
P04350 BXGT006193 Tubulin beta-4A chain reviewed Cellular structure TUBB4A TIME '=' 0 hr
Q71U36 BXGT016705 Tubulin alpha-1A chain reviewed Cellular structure TUBA1A TIME '=' 0 hr
Q13509 BXGT013366 Tubulin beta-3 chain reviewed Cellular structure TUBB3 TIME '=' 0 hr
P68366 BXGT011595 Tubulin alpha-4A chain reviewed Cellular structure TUBA4A TIME '=' 0 hr
P0DPH7 BXGT007527 Tubulin alpha-3C chain reviewed - TUBA3C TIME '=' 0 hr
Q9H4B7 BXGT020475 Tubulin beta-1 chain reviewed Cellular structure TUBB1 TIME '=' 0 hr
P68371 BXGT011597 Tubulin beta-4B chain reviewed Cellular structure TUBB4B TIME '=' 0 hr
P05177 BXGT006336 Cytochrome P450 1A2 reviewed Enzyme CYP1A2 AC50 '=' 25118 nM
Q9NR56 BXGT021179 Muscleblind-like protein 1 reviewed Nucleic acid binding MBNL1 Potency - 12589 nM
Q9BUF5 BXGT020135 Tubulin beta-6 chain reviewed Cellular structure TUBB6 IC50 '=' 1320 nM
Q9BVA1 BXGT020142 Tubulin beta-2B chain reviewed - TUBB2B IC50 '=' 1320 nM
Q13885 BXGT013400 Tubulin beta-2A chain reviewed Cellular structure TUBB2A IC50 '=' 1320 nM
Q6PEY2 BXGT016465 Tubulin alpha-3E chain reviewed Cellular structure TUBA3E IC50 '=' 1320 nM
Q9BQE3 BXGT020109 Tubulin alpha-1C chain reviewed Cellular structure TUBA1C IC50 '=' 1320 nM
P68363 BXGT011594 Tubulin alpha-1B chain reviewed Cellular structure TUBA1B IC50 '=' 1320 nM
P07437 BXGT006624 Tubulin beta chain reviewed Cellular structure TUBB IC50 '=' 1320 nM
Q3ZCM7 BXGT014551 Tubulin beta-8 chain reviewed - TUBB8 IC50 '=' 1320 nM
P04350 BXGT006193 Tubulin beta-4A chain reviewed Cellular structure TUBB4A IC50 '=' 1320 nM
Q71U36 BXGT016705 Tubulin alpha-1A chain reviewed Cellular structure TUBA1A IC50 '=' 1320 nM
Q13509 BXGT013366 Tubulin beta-3 chain reviewed Cellular structure TUBB3 IC50 '=' 1320 nM
P68366 BXGT011595 Tubulin alpha-4A chain reviewed Cellular structure TUBA4A IC50 '=' 1320 nM
P0DPH7 BXGT007527 Tubulin alpha-3C chain reviewed - TUBA3C IC50 '=' 1320 nM
Q9H4B7 BXGT020475 Tubulin beta-1 chain reviewed Cellular structure TUBB1 IC50 '=' 1320 nM
P68371 BXGT011597 Tubulin beta-4B chain reviewed Cellular structure TUBB4B IC50 '=' 1320 nM
P07437 BXGT006624 Tubulin beta chain reviewed Cellular structure TUBB IC50 '=' 6930 nM
Q9BUF5 BXGT020135 Tubulin beta-6 chain reviewed Cellular structure TUBB6 IC50 '=' 7800 nM
Q9BVA1 BXGT020142 Tubulin beta-2B chain reviewed - TUBB2B IC50 '=' 7800 nM
Q13885 BXGT013400 Tubulin beta-2A chain reviewed Cellular structure TUBB2A IC50 '=' 7800 nM
Q6PEY2 BXGT016465 Tubulin alpha-3E chain reviewed Cellular structure TUBA3E IC50 '=' 7800 nM
Q9BQE3 BXGT020109 Tubulin alpha-1C chain reviewed Cellular structure TUBA1C IC50 '=' 7800 nM
P68363 BXGT011594 Tubulin alpha-1B chain reviewed Cellular structure TUBA1B IC50 '=' 7800 nM
P07437 BXGT006624 Tubulin beta chain reviewed Cellular structure TUBB IC50 '=' 7800 nM
Q3ZCM7 BXGT014551 Tubulin beta-8 chain reviewed - TUBB8 IC50 '=' 7800 nM
P04350 BXGT006193 Tubulin beta-4A chain reviewed Cellular structure TUBB4A IC50 '=' 7800 nM
Q71U36 BXGT016705 Tubulin alpha-1A chain reviewed Cellular structure TUBA1A IC50 '=' 7800 nM
Q13509 BXGT013366 Tubulin beta-3 chain reviewed Cellular structure TUBB3 IC50 '=' 7800 nM
P68366 BXGT011595 Tubulin alpha-4A chain reviewed Cellular structure TUBA4A IC50 '=' 7800 nM
P0DPH7 BXGT007527 Tubulin alpha-3C chain reviewed - TUBA3C IC50 '=' 7800 nM
Q9H4B7 BXGT020475 Tubulin beta-1 chain reviewed Cellular structure TUBB1 IC50 '=' 7800 nM
P68371 BXGT011597 Tubulin beta-4B chain reviewed Cellular structure TUBB4B IC50 '=' 7800 nM
P07437 BXGT006624 Tubulin beta chain reviewed Cellular structure TUBB IC50 '=' 4590 nM
Foods  containing  the  compound
Foods
BXGF Id Food Name Scientific Name Food Group
BXGF Id Food Name Scientific Name Food Group
BXGF02133 Veratrum nigrum Veratrum nigrum Medicinal Plant
BXGF03771 Colchicum brachyphyllum Colchicum brachyphyllum Others
BXGF05261 Artemisia chinensis Artemisia chinensis Medicinal Plant
BXGF06140 Tanacetum parthenium Tanacetum parthenium Medicinal Plant
The  compound-realted  diseases
Diseases
BXGD Id Disease Name CUI Disease Id Disease Class Name Number of targets?Number of targets related to compound connecting disease, higher numbers indicate the compound is more associated with the disease