adisease

Showing entry for Drug toxicity

General Disease Information
BXGD Id	BXGD000804
Disease Name	Drug toxicity
Disease CUI Id	C0013221
MeSH Codes	C25
Disease Class Name	Chemically-Induced Disorders
Semantic Type	Injury or Poisoning
Human Phenotype Ontology Id
Human Phenotype Ontology Term
Disease Ontology Id
Disease Ontology Class Name
Disorder Network	disorder-protein-compound-food associations

The disease-related target proteins

Proteins

Uniport Id	BXGT Id	Protein Name	Gene	Status	Protein Class
Uniport Id	BXGT Id	Protein name	Gene	Status	Protein class
O00748	BXGT003942	Cocaine esterase	8824	reviewed	Enzyme
O14558	BXGT004070	Heat shock protein beta-6	126393	reviewed
O15439	BXGT004169	Multidrug resistance-associated protein 4	10257	reviewed	Transporter
O60603	BXGT004887	Toll-like receptor 2	7097	reviewed
O95180	BXGT005358	Voltage-dependent T-type calcium channel subunit alpha-1H	8912	reviewed	Ion channel
P00374	BXGT005520	Dihydrofolate reductase	1719	reviewed	Enzyme
P00441	BXGT005540	Superoxide dismutase [Cu-Zn]	6647	reviewed	Enzyme
P00450	BXGT005544	Ceruloplasmin	1356	reviewed	Enzyme
P00747	BXGT005639	Plasminogen	5340	reviewed	Enzyme
P00797	BXGT005658	Renin	5972	reviewed	Enzyme
P01009	BXGT005714	Alpha-1-antitrypsin	5265	reviewed	Enzyme modulator
P01024	BXGT005719	Complement C3	718	reviewed	Enzyme modulator
P01034	BXGT005721	Cystatin-C	1471	reviewed
P01889	BXGT005809	HLA class I histocompatibility antigen, B-7 alpha chain	3106	reviewed
P02671	BXGT005914	Fibrinogen alpha chain	2243	reviewed
P02760	BXGT005948	Protein AMBP	259	reviewed
P02763	BXGT005951	Alpha-1-acid glycoprotein 1	5004	reviewed
P02765	BXGT005952	Alpha-2-HS-glycoprotein	197	reviewed	Enzyme modulator
P02766	BXGT005953	Transthyretin	7276	reviewed	Transporter
P02768	BXGT005955	Serum albumin	213	reviewed	Transporter
P02774	BXGT005959	Vitamin D-binding protein	2638	reviewed	Transporter
P02787	BXGT005962	Serotransferrin	7018	reviewed	Enzyme
P04150	BXGT006154	Glucocorticoid receptor	2908	reviewed	Nuclear receptor
P04637	BXGT006243	Cellular tumor antigen p53	7157	reviewed	Transcription factor
P04818	BXGT006269	Thymidylate synthase	7298	reviewed	Enzyme
P05177	BXGT006336	Cytochrome P450 1A2	1544	reviewed	Enzyme
P05181	BXGT006337	Cytochrome P450 2E1	1571	reviewed
P06276	BXGT006430	Cholinesterase	590	reviewed
P07204	BXGT006567	Thrombomodulin	7056	reviewed
P08183	BXGT006741	ATP-dependent translocase ABCB1	5243	reviewed	Transporter
P08263	BXGT006759	Glutathione S-transferase A1	2938	reviewed
P08700	BXGT006816	Interleukin-3	3562	reviewed
P08833	BXGT006827	Insulin-like growth factor-binding protein 1	3484	reviewed	Enzyme modulator
P09429	BXGT006889	High mobility group protein B1	3146	reviewed	Nucleic acid binding
P09601	BXGT006909	Heme oxygenase 1	3162	reviewed
P10599	BXGT007583	Thioredoxin	7295	reviewed
P10632	BXGT007592	Cytochrome P450 2C8	1558	reviewed
P10635	BXGT007595	Cytochrome P450 2D6	1565	reviewed
P10909	BXGT007630	Clusterin	1191	reviewed
P11387	BXGT007696	DNA topoisomerase 1	7150	reviewed	Enzyme
P11712	BXGT007738	Cytochrome P450 2C9	1559	reviewed
P18440	BXGT008404	Arylamine N-acetyltransferase 1	9	reviewed	Enzyme
P20062	BXGT008543	Transcobalamin-2	6948	reviewed
P21583	BXGT008667	Kit ligand	4254	reviewed
P22303	BXGT008751	Acetylcholinesterase	43	reviewed	Enzyme
P22309	BXGT008753	UDP-glucuronosyltransferase 1-1	54658	reviewed
P29274	BXGT009327	Adenosine receptor A2a	135	reviewed	G-protein coupled receptor
P30542	BXGT009436	Adenosine receptor A1	134	reviewed	G-protein coupled receptor
P31939	BXGT009584	Bifunctional purine biosynthesis protein PURH	471	reviewed	Enzyme
P33527	BXGT009728	Multidrug resistance-associated protein 1	4363	reviewed	Transporter
P34896	BXGT009767	Serine hydroxymethyltransferase, cytosolic	6470	reviewed	Enzyme
P34913	BXGT009770	Bifunctional epoxide hydrolase 2	2053	reviewed	Enzyme
P35354	BXGT009816	Prostaglandin G/H synthase 2	5743	reviewed	Enzyme
P41440	BXGT010261	Folate transporter 1	6573	reviewed	Transporter
P41595	BXGT010267	5-hydroxytryptamine receptor 2B	3357	reviewed	G-protein coupled receptor
P42898	BXGT010344	Methylenetetrahydrofolate reductase	4524	reviewed
P43652	BXGT010405	Afamin	173	reviewed	Transporter
P61769	BXGT011383	Beta-2-microglobulin	567	reviewed	Immune response
P80188	BXGT011882	Neutrophil gelatinase-associated lipocalin	3934	reviewed	Enzyme
Q07869	BXGT012945	Peroxisome proliferator-activated receptor alpha	5465	reviewed	Nuclear receptor
Q15375	BXGT013562	Ephrin type-A receptor 7	2045	reviewed	Kinase
Q16236	BXGT013624	Nuclear factor erythroid 2-related factor 2	4780	reviewed	Enzyme
Q92887	BXGT019389	Canalicular multispecific organic anion transporter 1	1244	reviewed	Transporter
Q92959	BXGT019400	Solute carrier organic anion transporter family member 2A1	6578	reviewed	Transporter
Q96D42	BXGT019636	Hepatitis A virus cellular receptor 1	26762	reviewed
Q96EN8	BXGT019649	Molybdenum cofactor sulfurase	55034	reviewed
Q99707	BXGT019952	Methionine synthase	4548	reviewed
Q9BQB6	BXGT020108	Vitamin K epoxide reductase complex subunit 1	79001	reviewed	Enzyme
Q9NYY3	BXGT021264	Serine/threonine-protein kinase PLK2	10769	reviewed	Kinase
Q9UBK8	BXGT021655	Methionine synthase reductase	4552	reviewed
Q9UNQ0	BXGT021792	ATP-binding cassette sub-family G member 2	9429	reviewed	Transporter
Q9Y6L6	BXGT022334	Solute carrier organic anion transporter family member 1B1	10599	reviewed	Transporter
P00738	BXGT022874	Haptoglobin	3240	reviewed	Enzyme

The disease-related compounds

Compounds

BXGC Id	Compound Name	Structure	Molecular Weight	Number of targets^{?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease}

The disease-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compounds in food^{?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease}