Showing entry for Obsessive-Compulsive Disorder


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Disease Information
BXGD IdBXGD002084
Disease NameObsessive-Compulsive Disorder
Disease CUI IdC0028768
MeSH Codes F03  
Disease Class NameMental Disorders
Semantic TypeMental or Behavioral Dysfunction
Human Phenotype Ontology Id HP:0000707  
Human Phenotype Ontology TermAbnormality of the nervous system
Disease Ontology Id DOID:150  
Disease Ontology Class Namedisease of mental health
Disorder Network disorder-protein-compound-food associations
The  disease-related  target proteins
Proteins
Uniport Id BXGT Id Protein Name Gene Status Protein Class
Uniport Id BXGT Id Protein name Gene Status Protein class
A5X5Y0 BXGT001376 5-hydroxytryptamine receptor 3E 285242 reviewed Ion channel
O14656 BXGT004080 Torsin-1A 1861 reviewed Chaperone
O14770 BXGT004095 Homeobox protein Meis2 4212 reviewed Enzyme
O75015 BXGT005095 Low affinity immunoglobulin gamma Fc region receptor III-B 2215 reviewed Cell adhesion
O75751 BXGT005150 Solute carrier family 22 member 3 6581 reviewed Transporter
O95264 BXGT005367 5-hydroxytryptamine receptor 3B 9177 reviewed Ion channel
P01100 BXGT005727 Proto-oncogene c-Fos 2353 reviewed Transcription factor
P01303 BXGT005748 Pro-neuropeptide Y 4852 reviewed Signaling
P01375 BXGT005753 Tumor necrosis factor 7124 reviewed Signaling
P01579 BXGT005770 Interferon gamma 3458 reviewed
P01583 BXGT005771 Interleukin-1 alpha 3552 reviewed
P01584 BXGT005772 Interleukin-1 beta 3553 reviewed
P01911 BXGT005816 HLA class II histocompatibility antigen, DRB1-15 beta chain 3123 reviewed Immune response
P03372 BXGT006059 Estrogen receptor 2099 reviewed Nuclear receptor
P04406 BXGT006207 Glyceraldehyde-3-phosphate dehydrogenase 2597 reviewed Enzyme
P04818 BXGT006269 Thymidylate synthase 7298 reviewed Enzyme
P05231 BXGT006345 Interleukin-6 3569 reviewed
P08637 BXGT006802 Low affinity immunoglobulin gamma Fc region receptor III-A 2214 reviewed Cell adhesion
P08908 BXGT006837 5-hydroxytryptamine receptor 1A 3350 reviewed G-protein coupled receptor
P09486 BXGT006897 SPARC 6678 reviewed Signaling
P09848 BXGT006929 Lactase-phlorizin hydrolase 3938 reviewed Enzyme
P10145 BXGT007542 Interleukin-8 3576 reviewed Signaling
P10599 BXGT007583 Thioredoxin 7295 reviewed
P10635 BXGT007595 Cytochrome P450 2D6 1565 reviewed
P11511 BXGT007717 Aromatase 1588 reviewed Enzyme
P13500 BXGT007916 C-C motif chemokine 2 6347 reviewed Signaling
P14416 BXGT008011 D(2) dopamine receptor 1813 reviewed G-protein coupled receptor
P16442 BXGT008227 Histo-blood group ABO system transferase 28 reviewed Enzyme
P18074 BXGT008374 General transcription and DNA repair factor IIH helicase subunit XPD 2068 reviewed Enzyme
P18507 BXGT008411 Gamma-aminobutyric acid receptor subunit gamma-2 2566 reviewed Ion channel
P19623 BXGT008503 Spermidine synthase 6723 reviewed Enzyme
P21397 BXGT008644 Amine oxidase [flavin-containing] A 4128 reviewed
P21554 BXGT008662 Cannabinoid receptor 1 1268 reviewed G-protein coupled receptor
P21728 BXGT008686 D(1A) dopamine receptor 1812 reviewed G-protein coupled receptor
P21917 BXGT008707 D(4) dopamine receptor 1815 reviewed G-protein coupled receptor
P21964 BXGT008714 Catechol O-methyltransferase 1312 reviewed Enzyme
P22607 BXGT008784 Fibroblast growth factor receptor 3 2261 reviewed Kinase
P23560 BXGT008883 Brain-derived neurotrophic factor 627 reviewed Signaling
P28221 BXGT009237 5-hydroxytryptamine receptor 1D 3352 reviewed G-protein coupled receptor
P28222 BXGT009238 5-hydroxytryptamine receptor 1B 3351 reviewed G-protein coupled receptor
P28223 BXGT009239 5-hydroxytryptamine receptor 2A 3356 reviewed G-protein coupled receptor
P28335 BXGT009255 5-hydroxytryptamine receptor 2C 3358 reviewed G-protein coupled receptor
P28482 BXGT009263 Mitogen-activated protein kinase 1 5594 reviewed Kinase
P29033 BXGT009308 Gap junction beta-2 protein 2706 reviewed Cell-cell junction
P29323 BXGT009334 Ephrin type-B receptor 2 2048 reviewed Kinase
P29475 BXGT009353 Nitric oxide synthase, brain 4842 reviewed
P30044 BXGT009395 Peroxiredoxin-5, mitochondrial 25824 reviewed
P30536 BXGT009435 Translocator protein 706 reviewed
P30559 BXGT009442 Oxytocin receptor 5021 reviewed G-protein coupled receptor
P30626 BXGT009450 Sorcin 6717 reviewed
P30793 BXGT009466 GTP cyclohydrolase 1 2643 reviewed Enzyme
P31645 BXGT009558 Sodium-dependent serotonin transporter 6532 reviewed Transporter
P32239 BXGT009612 Gastrin/cholecystokinin type B receptor 887 reviewed G-protein coupled receptor
P33261 BXGT009707 Cytochrome P450 2C19 1557 reviewed
P35372 BXGT009823 Mu-type opioid receptor 4988 reviewed G-protein coupled receptor
P35462 BXGT009835 D(3) dopamine receptor 1814 reviewed G-protein coupled receptor
P41594 BXGT010266 Metabotropic glutamate receptor 5 2915 reviewed G-protein coupled receptor
P41595 BXGT010267 5-hydroxytryptamine receptor 2B 3357 reviewed G-protein coupled receptor
P42263 BXGT010295 Glutamate receptor 3 2892 reviewed Ion channel
P42858 BXGT010341 Huntingtin 3064 reviewed
P42898 BXGT010344 Methylenetetrahydrofolate reductase 4524 reviewed
P43003 BXGT010347 Excitatory amino acid transporter 1 6507 reviewed Transporter
P43004 BXGT010348 Excitatory amino acid transporter 2 6506 reviewed Transporter
P43005 BXGT010349 Excitatory amino acid transporter 3 6505 reviewed Transporter
P46098 BXGT010507 5-hydroxytryptamine receptor 3A 3359 reviewed Ion channel
P52803 BXGT010958 Ephrin-A5 1946 reviewed Signaling
P54219 BXGT011037 Chromaffin granule amine transporter 6570 reviewed Transporter
P60709 BXGT011322 Actin, cytoplasmic 1 60 reviewed Cellular structure
P78352 BXGT011836 Disks large homolog 4 1742 reviewed Receptor
P98164 BXGT012230 Low-density lipoprotein receptor-related protein 2 4036 reviewed
Q01959 BXGT012624 Sodium-dependent dopamine transporter 6531 reviewed Transporter
Q05329 BXGT012814 Glutamate decarboxylase 2 2572 reviewed Enzyme
Q08499 BXGT012988 cAMP-specific 3',5'-cyclic phosphodiesterase 4D 5144 reviewed
Q13002 BXGT013303 Glutamate receptor ionotropic, kainate 2 2898 reviewed Ion channel
Q13003 BXGT013304 Glutamate receptor ionotropic, kainate 3 2899 reviewed Ion channel
Q13085 BXGT013309 Acetyl-CoA carboxylase 1 31 reviewed
Q13224 BXGT013328 Glutamate receptor ionotropic, NMDA 2B 2904 reviewed Ion channel
Q13427 BXGT013354 Peptidyl-prolyl cis-trans isomerase G 9360 reviewed
Q13451 BXGT013356 Peptidyl-prolyl cis-trans isomerase FKBP5 2289 reviewed Enzyme
Q13936 BXGT013404 Voltage-dependent L-type calcium channel subunit alpha-1C 775 reviewed Ion channel
Q15223 BXGT013551 Nectin-1 5818 reviewed
Q15413 BXGT013568 Ryanodine receptor 3 6263 reviewed Ion channel
Q16288 BXGT013625 NT-3 growth factor receptor 4916 reviewed Kinase
Q16620 BXGT013645 BDNF/NT-3 growth factors receptor 4915 reviewed Kinase
Q59FK2 BXGT015276 Selenocysteine lyase variant 51540 unreviewed
Q5VZ30 BXGT015894 Glutamate decarboxylase 2 (Pancreatic islets and brain, 65kDa) 2572 unreviewed
Q6W5P4 BXGT016588 Neuropeptide S receptor 387129 reviewed
Q70Z44 BXGT016686 5-hydroxytryptamine receptor 3D 200909 reviewed Ion channel
Q86TW2 BXGT017609 Uncharacterized aarF domain-containing protein kinase 1 57143 reviewed Kinase
Q8WXA8 BXGT019008 5-hydroxytryptamine receptor 3C 170572 reviewed Ion channel
Q92731 BXGT019366 Estrogen receptor beta 2100 reviewed Nuclear receptor
Q96I15 BXGT019674 Selenocysteine lyase 51540 reviewed Enzyme
Q99572 BXGT019935 P2X purinoceptor 7 5027 reviewed Ion channel
Q9BY08 BXGT020177 Emopamil-binding protein-like 84650 reviewed Enzyme
Q9H3R0 BXGT020465 Lysine-specific demethylase 4C 23081 reviewed
Q9NR12 BXGT021174 PDZ and LIM domain protein 7 9260 reviewed Cellular structure
Q9NY46 BXGT021248 Sodium channel protein type 3 subunit alpha 6328 reviewed Ion channel
Q9UBS5 BXGT021662 Gamma-aminobutyric acid type B receptor subunit 1 2550 reviewed G-protein coupled receptor
Q9Y3Q4 BXGT022264 Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 10021 reviewed Ion channel
Q9Y6D6 BXGT022326 Brefeldin A-inhibited guanine nucleotide-exchange protein 1 10565 reviewed
Q16760 BXGT022666 Diacylglycerol kinase delta 8527 reviewed Enzyme
Q16552 BXGT023419 Interleukin-17A 3605 reviewed
O14490 BXGT023570 Disks large-associated protein 1 9229 reviewed Receptor
Q14807 BXGT024966 Kinesin-like protein KIF22 3835 reviewed Cellular structure
P51608 BXGT025073 Methyl-CpG-binding protein 2 4204 reviewed Epigenetic regulator
Q86SQ9 BXGT025875 Dehydrodolichyl diphosphate synthase complex subunit DHDDS 79947 reviewed Enzyme
The  disease-related  compounds
Compounds
BXGC Id Compound Name Structure Molecular Weight Number of targets?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease
The  disease-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compounds in food?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease