adisease

Showing entry for Osteomyelitis

General Disease Information
BXGD Id	BXGD002152
Disease Name	Osteomyelitis
Disease CUI Id	C0029443
MeSH Codes	C01 C05
Disease Class Name	Infections; Musculoskeletal Diseases
Semantic Type	Disease or Syndrome
Human Phenotype Ontology Id	HP:0002715 HP:0000924
Human Phenotype Ontology Term	Abnormality of the immune system; Abnormality of the skeletal system
Disease Ontology Id	DOID:7
Disease Ontology Class Name	disease of anatomical entity
Disorder Network	disorder-protein-compound-food associations

The disease-related target proteins

Proteins

Uniport Id	BXGT Id	Protein Name	Gene	Status	Protein Class
Uniport Id	BXGT Id	Protein name	Gene	Status	Protein class
O00206	BXGT003894	Toll-like receptor 4	7099	reviewed
O14788	BXGT004100	Tumor necrosis factor ligand superfamily member 11	8600	reviewed	Signaling
O15270	BXGT004146	Serine palmitoyltransferase 2	9517	reviewed	Enzyme
O60603	BXGT004887	Toll-like receptor 2	7097	reviewed
O95243	BXGT005362	Methyl-CpG-binding domain protein 4	8930	reviewed	Enzyme
O95644	BXGT005389	Nuclear factor of activated T-cells, cytoplasmic 1	4772	reviewed	Transcription factor
P00390	BXGT005526	Glutathione reductase, mitochondrial	2936	reviewed	Enzyme
P01138	BXGT005738	Beta-nerve growth factor	4803	reviewed	Signaling
P01375	BXGT005753	Tumor necrosis factor	7124	reviewed	Signaling
P01579	BXGT005770	Interferon gamma	3458	reviewed
P01583	BXGT005771	Interleukin-1 alpha	3552	reviewed
P01584	BXGT005772	Interleukin-1 beta	3553	reviewed
P01911	BXGT005816	HLA class II histocompatibility antigen, DRB1-15 beta chain	3123	reviewed	Immune response
P01920	BXGT005817	HLA class II histocompatibility antigen, DQ beta 1 chain	3119	reviewed	Immune response
P02741	BXGT005936	C-reactive protein	1401	reviewed
P02751	BXGT005943	Fibronectin	2335	reviewed	Signaling
P02768	BXGT005955	Serum albumin	213	reviewed	Transporter
P03956	BXGT006120	Interstitial collagenase	4312	reviewed	Enzyme
P04629	BXGT006239	High affinity nerve growth factor receptor	4914	reviewed	Kinase
P04839	BXGT006273	Cytochrome b-245 heavy chain	1536	reviewed	Ion channel
P05089	BXGT006310	Arginase-1	383	reviewed	Enzyme
P05121	BXGT006320	Plasminogen activator inhibitor 1	5054	reviewed	Enzyme modulator
P05231	BXGT006345	Interleukin-6	3569	reviewed
P08311	BXGT006762	Cathepsin G	1511	reviewed	Enzyme
P09038	BXGT006851	Fibroblast growth factor 2	2247	reviewed	Signaling
P09848	BXGT006929	Lactase-phlorizin hydrolase	3938	reviewed	Enzyme
P10147	BXGT007543	C-C motif chemokine 3	6348	reviewed	Signaling
P11912	BXGT007758	B-cell antigen receptor complex-associated protein alpha chain	973	reviewed	Receptor
P13500	BXGT007916	C-C motif chemokine 2	6347	reviewed	Signaling
P14598	BXGT008024	Neutrophil cytosol factor 1	653361	reviewed
P14921	BXGT008068	Protein C-ets-1	2113	reviewed	Transcription factor
P15428	BXGT008121	15-hydroxyprostaglandin dehydrogenase [NAD(+)]	3248	reviewed
P15814	BXGT008159	Immunoglobulin lambda-like polypeptide 1	3543	reviewed
P17301	BXGT008299	Integrin alpha-2	3673	reviewed
P20810	BXGT008602	Calpastatin	831	reviewed
P26358	BXGT009104	DNA (cytosine-5)-methyltransferase 1	1786	reviewed	Epigenetic regulator
P27986	BXGT009216	Phosphatidylinositol 3-kinase regulatory subunit alpha	5295	reviewed	Kinase
P29474	BXGT009352	Nitric oxide synthase, endothelial	4846	reviewed
P35354	BXGT009816	Prostaglandin G/H synthase 2	5743	reviewed	Enzyme
P36222	BXGT009914	Chitinase-3-like protein 1	1116	reviewed
P36551	BXGT009927	Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial	1371	reviewed	Enzyme
P40763	BXGT010202	Signal transducer and activator of transcription 3	6774	reviewed	Nucleic acid binding
P41182	BXGT010231	B-cell lymphoma 6 protein	604	reviewed
P42224	BXGT010286	Signal transducer and activator of transcription 1-alpha/beta	6772	reviewed	Nucleic acid binding
P43235	BXGT010368	Cathepsin K	1513	reviewed	Enzyme
P43405	BXGT010386	Tyrosine-protein kinase SYK	6850	reviewed	Kinase
P45452	BXGT010462	Collagenase 3	4322	reviewed	Enzyme
P51681	BXGT010878	C-C chemokine receptor type 5	1234	reviewed	G-protein coupled receptor
P61073	BXGT011352	C-X-C chemokine receptor type 4	7852	reviewed	G-protein coupled receptor
P68871	BXGT011615	Hemoglobin subunit beta	3043	reviewed
Q06187	BXGT012860	Tyrosine-protein kinase BTK	695	reviewed	Kinase
Q07812	BXGT012940	Apoptosis regulator BAX	581	reviewed	Signaling
Q13478	BXGT013362	Interleukin-18 receptor 1	8809	reviewed	Receptor
Q13625	BXGT013384	Apoptosis-stimulating of p53 protein 2	7159	reviewed	Enzyme modulator
Q14627	BXGT013492	Interleukin-13 receptor subunit alpha-2	3598	reviewed	Signaling
Q15125	BXGT013543	3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase	10682	reviewed	Enzyme
Q15392	BXGT013566	Delta(24)-sterol reductase	1718	reviewed	Enzyme
Q15637	BXGT013586	Splicing factor 1	7536	reviewed	Nucleic acid binding
Q16665	BXGT013653	Hypoxia-inducible factor 1-alpha	3091	reviewed	Transcription factor
Q5Y7D3	BXGT015912	HLA class II histocompatibility antigen DQ beta chain	3119	unreviewed
Q6ZMJ4	BXGT016628	Interleukin-34	146433	reviewed
Q8NBJ7	BXGT018537	Inactive C-alpha-formylglycine-generating enzyme 2	25870	reviewed
Q8WXF7	BXGT019011	Atlastin-1	51062	reviewed	Enzyme modulator
Q92959	BXGT019400	Solute carrier organic anion transporter family member 2A1	6578	reviewed	Transporter
Q96P20	BXGT019704	NACHT, LRR and PYD domains-containing protein 3	114548	reviewed
Q99836	BXGT019970	Myeloid differentiation primary response protein MyD88	4615	reviewed	Enzyme modulator
Q9BZS1	BXGT020203	Forkhead box protein P3	50943	reviewed
Q9Y572	BXGT022289	Receptor-interacting serine/threonine-protein kinase 3	11035	reviewed	Kinase
Q9Y6K9	BXGT022333	NF-kappa-B essential modulator	8517	reviewed	Kinase
P19875	BXGT023294	C-X-C motif chemokine 2	2920	reviewed	Signaling
Q16552	BXGT023419	Interleukin-17A	3605	reviewed
P15260	BXGT023924	Interferon gamma receptor 1	3459	reviewed	Receptor
Q13635	BXGT024910	Protein patched homolog 1	5727	reviewed
P51798	BXGT026083	H(+)/Cl(-) exchange transporter 7	1186	reviewed	Ion channel

The disease-related compounds

Compounds

BXGC Id	Compound Name	Structure	Molecular Weight	Number of targets^{?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease}

The disease-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compounds in food^{?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease}