Showing entry for Atlastin-1


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT019011
Protein NameAtlastin-1
Uniport IdQ8WXF7
GeneATL1
Gene Id51062
DomainGBP
Pfam PF02263  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0007409 axonogenesis
Biological Process GO:0007029 endoplasmic reticulum organization
Biological Process GO:1990809 endoplasmic reticulum tubular network membrane organization
Biological Process GO:0051260 protein homooligomerization
molecular function GO:0003924 GTPase activity
molecular function GO:0005525 GTP binding
molecular function GO:0042802 identical protein binding
cellular component GO:0030424 axon
cellular component GO:0005783 endoplasmic reticulum
cellular component GO:0005789 endoplasmic reticulum membrane
cellular component GO:0071782 endoplasmic reticulum tubular network
cellular component GO:0098826 endoplasmic reticulum tubular network membrane
cellular component GO:0005794 Golgi apparatus
cellular component GO:0000137 Golgi cis cisterna
cellular component GO:0000139 Golgi membrane
cellular component GO:0016021 integral component of membrane
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0002736 BXGD000127 Amyotrophic Lateral Sclerosis Nutritional and Metabolic Diseases; Nervous System Diseases
C0005890 BXGD000345 Body Height
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0007222 BXGD000454 Cardiovascular Diseases Cardiovascular Diseases
C0013312 BXGD000814 Dupuytren Contracture Neoplasms; Skin and Connective Tissue Diseases; Musculoskeletal Diseases
C0013362 BXGD000817 Dysarthria Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0013363 BXGD000818 Dysautonomia Nervous System Diseases
C0014544 BXGD000926 Epilepsy Nervous System Diseases
C0014556 BXGD000932 Epilepsy, Temporal Lobe Nervous System Diseases
C0015934 BXGD001026 Fetal Growth Retardation Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications
C0017668 BXGD001143 Focal glomerulosclerosis Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0020071 BXGD001356 Hereditary Sensory Autonomic Neuropathy, Type 1 Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0020453 BXGD001390 Hyperesthesia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0020538 BXGD001422 Hypertensive disease Cardiovascular Diseases
C0023493 BXGD001672 Adult T-Cell Lymphoma/Leukemia Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0026650 BXGD001913 Movement Disorders Nervous System Diseases
C0026837 BXGD001937 Muscle Rigidity Pathological Conditions, Signs and Symptoms; Musculoskeletal Diseases; Nervous System Diseases
C0026838 BXGD001938 Muscle Spasticity Pathological Conditions, Signs and Symptoms; Musculoskeletal Diseases; Nervous System Diseases
C0027051 BXGD001963 Myocardial Infarction Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0027627 BXGD002006 Neoplasm Metastasis Pathological Conditions, Signs and Symptoms; Neoplasms
C0027651 BXGD002009 Neoplasms Neoplasms
C0027765 BXGD002033 nervous system disorder Nervous System Diseases
C0027819 BXGD002043 Neuroblastoma Neoplasms
C0027889 BXGD002057 Hereditary Sensory and Autonomic Neuropathies Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0027902 BXGD002058 Neuropsychological Tests
C0029443 BXGD002152 Osteomyelitis Infections; Musculoskeletal Diseases
C0030486 BXGD002229 Paraplegia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0030554 BXGD002239 Paresthesia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0031117 BXGD002285 Peripheral Neuropathy Nervous System Diseases
C0034152 BXGD002467 Henoch-Schoenlein Purpura Pathological Conditions, Signs and Symptoms; Immune System Diseases; Hemic and Lymphatic Diseases; Cardiovascular Diseases
C0034935 BXGD002497 Babinski Reflex
C0035258 BXGD002523 Restless Legs Syndrome Nervous System Diseases; Mental Disorders
C0036439 BXGD002615 Scoliosis, unspecified Musculoskeletal Diseases
C0036572 BXGD002625 Seizures Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0037772 BXGD002703 Spastic Paraplegia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0037773 BXGD002704 Spastic Paraplegia, Hereditary Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0039273 BXGD002806 Talipes cavus Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0042024 BXGD002949 Urinary Incontinence Pathological Conditions, Signs and Symptoms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0085084 BXGD003121 Motor Neuron Disease Nervous System Diseases
C0085606 BXGD003201 Urgency of micturition Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0085786 BXGD003252 Hamman-Rich syndrome Pathological Conditions, Signs and Symptoms; Infections; Respiratory Tract Diseases
C0151313 BXGD003413 Sensory neuropathy Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0151889 BXGD003498 Hyperreflexia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0178664 BXGD004032 Glomerulosclerosis (disorder) Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases; Cardiovascular Diseases
C0178874 BXGD004037 Tumor Progression Pathological Conditions, Signs and Symptoms
C0221163 BXGD004395 Motor Disorders Mental Disorders
C0221260 BXGD004424 Dystrophia unguium Pathological Conditions, Signs and Symptoms; Skin and Connective Tissue Diseases
C0231687 BXGD004509 Spastic gait Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0233565 BXGD004590 Bradykinesia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0235025 BXGD004713 Peripheral motor neuropathy Nervous System Diseases
C0238651 BXGD004951 Ankle clonus
C0242379 BXGD005157 Malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C0265344 BXGD005527 Donohue Syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Musculoskeletal Diseases; Endocrine System Diseases
C0270804 BXGD006107 Spastic Diplegia Cerebral Palsy Nervous System Diseases
C0270921 BXGD006133 Axonal neuropathy Nervous System Diseases
C0338656 BXGD007211 Impaired cognition Mental Disorders
C0376358 BXGD007992 Malignant neoplasm of prostate Neoplasms; Male Urogenital Diseases
C0393555 BXGD008088 Pure hereditary spastic paraplegia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0427144 BXGD008607 Toe-walking gait
C0442874 BXGD008814 Neuropathy Nervous System Diseases
C0456070 BXGD008863 Growth delay
C0520947 BXGD009126 Clumsiness - motor delay Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
C0524851 BXGD009246 Neurodegenerative Disorders Nervous System Diseases
C0600139 BXGD009695 Prostate carcinoma Neoplasms; Male Urogenital Diseases
C0678222 BXGD009749 Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C0684249 BXGD009790 Carcinoma of lung Neoplasms; Respiratory Tract Diseases
C0686619 BXGD009835 Secondary malignant neoplasm of lymph node Pathological Conditions, Signs and Symptoms; Neoplasms
C0699739 BXGD009861 Sensory Neuropathy, Hereditary Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0700095 BXGD009875 Central neuroblastoma Neoplasms; Nervous System Diseases
C0751602 BXGD010520 Hereditary Autosomal Dominant Spastic Paraplegia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0850703 BXGD010905 Frequent falls Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0871470 BXGD011316 Systolic Pressure
C1263857 BXGD011900 Peripheral axonal neuropathy Nervous System Diseases
C1269955 BXGD012005 Tumor Cell Invasion
C1271100 BXGD012007 Lower limb spasticity Pathological Conditions, Signs and Symptoms; Musculoskeletal Diseases; Nervous System Diseases
C1295585 BXGD012241 Decreased vibratory sense Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C1306460 BXGD012362 Primary malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C1527349 BXGD013277 Ductal Breast Carcinoma Neoplasms
C1535926 BXGD013322 Neurodevelopmental Disorders Mental Disorders
C1561643 BXGD013363 Chronic Kidney Diseases Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C1611743 BXGD013456 Familial (FPAH)
C1833222 BXGD013903 Autoamputation
C1834405 BXGD013970 Nail dysplasia Pathological Conditions, Signs and Symptoms
C1836296 BXGD014105 Muscle Weakness Lower Limb Pathological Conditions, Signs and Symptoms; Musculoskeletal Diseases; Nervous System Diseases
C1836450 BXGD014117 Distal lower limb muscle weakness
C1836451 BXGD014118 Distal lower limb amyotrophy
C1836527 BXGD014127 Distal sensory impairment of all modalities
C1836696 BXGD014151 Lower limb hyperreflexia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C1843663 BXGD014600 Urinary bladder sphincter dysfunction
C1845245 BXGD014730 Lower limb hypertonia
C1846566 BXGD014829 Degeneration of the lateral corticospinal tracts
C1847584 BXGD014876 Distal sensory impairment Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C1848736 BXGD014970 Distal amyotrophy
C1849134 BXGD015010 Impaired vibration sensation in the lower limbs
C1854301 BXGD015391 Motor delay Mental Disorders
C1858712 BXGD015821 Spastic paraplegia 10, autosomal dominant Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C1861403 BXGD016045 Variable expressivity
C1864975 BXGD016279 Osteomyelitis leading to amputation due to slow healing fractures Infections; Musculoskeletal Diseases
C1866855 BXGD016426 Spastic paraplegia 4, autosomal dominant Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C1970009 BXGD016802 SPASTIC PARAPLEGIA 32, AUTOSOMAL RECESSIVE Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
C2931355 BXGD018006 Spastic paraplegia 3, autosomal dominant Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C2939419 BXGD018178 Secondary Neoplasm Pathological Conditions, Signs and Symptoms; Neoplasms
C3150972 BXGD018368 NEUROPATHY, HEREDITARY SENSORY, TYPE ID
C3279947 BXGD018789 NAIL DISORDER, NONSYNDROMIC CONGENITAL, 9
C3711371 BXGD019381 Spastic Paraplegia Type 4 Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C3714756 BXGD019429 Intellectual Disability Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
C4025809 BXGD021801 Penetrating foot ulcers Skin and Connective Tissue Diseases
C4086165 BXGD022126 Childhood Neuroblastoma Neoplasms
C4553976 BXGD023554 Urinary Urgency, CTCAE 5
C4721453 BXGD023744 Peripheral Nervous System Diseases Nervous System Diseases
C4721509 BXGD023749 Usual Interstitial Pneumonia Respiratory Tract Diseases
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000436 Glycerol 92.09
BXGC0002588 Magnesium 24.31
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein