Showing entry for Fructose-bisphosphate aldolase B


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT006305
Protein NameFructose-bisphosphate aldolase B
Uniport IdP05062
GeneALDOB
Gene Id229
DomainGlycolytic
Pfam PF00274  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
1. Metabolism 1.1 Carbohydrate metabolism hsa00010 Glycolysis / Gluconeogenesis
1. Metabolism 1.1 Carbohydrate metabolism hsa00030 Pentose phosphate pathway
1. Metabolism 1.1 Carbohydrate metabolism hsa00051 Fructose and mannose metabolism
1. Metabolism 1.0 Global and overview maps hsa01100 Metabolic pathways
1. Metabolism 1.0 Global and overview maps hsa01200 Carbon metabolism
1. Metabolism 1.0 Global and overview maps hsa01230 Biosynthesis of amino acids
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0061621 canonical glycolysis
Biological Process GO:0030388 fructose 1,6-bisphosphate metabolic process
Biological Process GO:0061624 fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate
Biological Process GO:0006000 fructose metabolic process
Biological Process GO:0006094 gluconeogenesis
Biological Process GO:0006096 glycolytic process
Biological Process GO:0006116 NADH oxidation
Biological Process GO:0032781 positive regulation of ATPase activity
Biological Process GO:0070072 vacuolar proton-transporting V-type ATPase complex assembly
molecular function GO:0051117 ATPase binding
molecular function GO:0008092 cytoskeletal protein binding
molecular function GO:0061609 fructose-1-phosphate aldolase activity
molecular function GO:0070061 fructose binding
molecular function GO:0004332 fructose-bisphosphate aldolase activity
molecular function GO:0042802 identical protein binding
cellular component GO:0034451 centriolar satellite
cellular component GO:0005829 cytosol
cellular component GO:0070062 extracellular exosome
cellular component GO:0005815 microtubule organizing center
Reactome
Pathway Id Pathway Name
R-HSA-1430728 Metabolism
R-HSA-1643685 Disease
R-HSA-5652084 Fructose metabolism
R-HSA-5657560 Hereditary fructose intolerance
R-HSA-5663084 Diseases of carbohydrate metabolism
R-HSA-5668914 Diseases of metabolism
R-HSA-70171 Glycolysis
R-HSA-70263 Gluconeogenesis
R-HSA-70326 Glucose metabolism
R-HSA-70350 Fructose catabolism
R-HSA-71387 Metabolism of carbohydrates
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0000731 BXGD000002 Abdomen distended Digestive System Diseases
C0000737 BXGD000005 Abdominal Pain Pathological Conditions, Signs and Symptoms
C0001125 BXGD000024 Acidosis, Lactic Nutritional and Metabolic Diseases
C0003129 BXGD000182 Anoxemia Pathological Conditions, Signs and Symptoms
C0003130 BXGD000183 Anoxia Pathological Conditions, Signs and Symptoms
C0005779 BXGD000336 Blood Coagulation Disorders Hemic and Lymphatic Diseases
C0007113 BXGD000430 Rectal Carcinoma Digestive System Diseases; Neoplasms
C0007134 BXGD000443 Renal Cell Carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0009324 BXGD000597 Ulcerative Colitis Digestive System Diseases
C0009402 BXGD000605 Colorectal Carcinoma Digestive System Diseases; Neoplasms
C0009421 BXGD000608 Comatose Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0009806 BXGD000633 Constipation Pathological Conditions, Signs and Symptoms
C0011853 BXGD000752 Diabetes Mellitus, Experimental Nutritional and Metabolic Diseases; Endocrine System Diseases
C0011860 BXGD000755 Diabetes Mellitus, Non-Insulin-Dependent Nutritional and Metabolic Diseases; Endocrine System Diseases
C0011991 BXGD000766 Diarrhea Pathological Conditions, Signs and Symptoms
C0015544 BXGD001003 Failure to Thrive Pathological Conditions, Signs and Symptoms
C0015695 BXGD001013 Fatty Liver Digestive System Diseases
C0016751 BXGD001077 Hereditary fructose intolerance syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases
C0017181 BXGD001103 Gastrointestinal Hemorrhage Pathological Conditions, Signs and Symptoms; Digestive System Diseases
C0017979 BXGD001159 Glycosuria Nutritional and Metabolic Diseases; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0019193 BXGD001299 Hepatitis, Toxic Digestive System Diseases; Chemically-Induced Disorders
C0019209 BXGD001305 Hepatomegaly Pathological Conditions, Signs and Symptoms; Digestive System Diseases
C0020433 BXGD001379 Hyperbilirubinemia Pathological Conditions, Signs and Symptoms
C0020456 BXGD001392 Hyperglycemia Nutritional and Metabolic Diseases
C0020615 BXGD001445 Hypoglycemia Nutritional and Metabolic Diseases
C0022346 BXGD001537 Icterus Pathological Conditions, Signs and Symptoms
C0023380 BXGD001640 Lethargy Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Behavior and Behavior Mechanisms
C0023890 BXGD001713 Liver Cirrhosis Pathological Conditions, Signs and Symptoms; Digestive System Diseases
C0024623 BXGD001791 Malignant neoplasm of stomach Digestive System Diseases; Neoplasms
C0027497 BXGD001993 Nausea Pathological Conditions, Signs and Symptoms
C0027651 BXGD002009 Neoplasms Neoplasms
C0028754 BXGD002082 Obesity Pathological Conditions, Signs and Symptoms; Nutritional and Metabolic Diseases
C0029823 BXGD002173 Other specified peritonitis Digestive System Diseases; Infections
C0036572 BXGD002625 Seizures Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0038356 BXGD002747 Stomach Neoplasms Digestive System Diseases; Neoplasms
C0042963 BXGD003018 Vomiting Pathological Conditions, Signs and Symptoms
C0085682 BXGD003238 Hypophosphatemia Nutritional and Metabolic Diseases
C0086543 BXGD003294 Cataract Eye Diseases
C0149670 BXGD003345 Disorder of carbohydrate metabolism Nutritional and Metabolic Diseases
C0151714 BXGD003463 Hypermagnesemia Nutritional and Metabolic Diseases
C0162429 BXGD003942 Malnutrition Nutritional and Metabolic Diseases
C0162557 BXGD003956 Liver Failure, Acute Digestive System Diseases
C0206677 BXGD004234 Adenomatous Polyps Neoplasms
C0220981 BXGD004348 Metabolic acidosis Nutritional and Metabolic Diseases
C0241910 BXGD005123 Autoimmune Chronic Hepatitis Digestive System Diseases; Immune System Diseases
C0242184 BXGD005140 Hypoxia Pathological Conditions, Signs and Symptoms
C0265325 BXGD005516 Turcot syndrome (disorder) Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Digestive System Diseases; Neoplasms; Nervous System Diseases
C0268435 BXGD005945 Renal Tubular Acidosis, Type II Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0271710 BXGD006245 Reactive hypoglycemia Nutritional and Metabolic Diseases
C0279702 BXGD006685 Conventional (Clear Cell) Renal Cell Carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0282201 BXGD006799 Phosphate Diabetes Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0400966 BXGD008266 Non-alcoholic Fatty Liver Disease Digestive System Diseases
C0456070 BXGD008863 Growth delay
C0700292 BXGD009884 Hypoxemia Pathological Conditions, Signs and Symptoms
C0740394 BXGD009989 Hyperuricemia Pathological Conditions, Signs and Symptoms
C0860207 BXGD011220 Drug-Induced Liver Disease Digestive System Diseases; Chemically-Induced Disorders
C0948643 BXGD011545 Hyperuricosuria
C1262760 BXGD011886 Hepatitis, Drug-Induced Digestive System Diseases; Chemically-Induced Disorders
C1333419 BXGD012624 Liver and Intrahepatic Bile Duct Epithelial Neoplasm
C1333976 BXGD012662 Liver and Intrahepatic Bile Duct Neoplasm Digestive System Diseases
C1522135 BXGD013253 Hypermagnesemia result
C1561643 BXGD013363 Chronic Kidney Diseases Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C1623038 BXGD013475 Cirrhosis Pathological Conditions, Signs and Symptoms
C1708349 BXGD013597 Hereditary Diffuse Gastric Cancer Digestive System Diseases; Neoplasms
C1839603 BXGD014388 Proximal tubulopathy Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C1839865 BXGD014420 Bicarbonaturia
C1848701 BXGD014967 Elevated hepatic transaminase
C1857171 BXGD015680 Episodic hyperhidrosis Skin and Connective Tissue Diseases
C2239176 BXGD016965 Liver carcinoma Digestive System Diseases; Neoplasms
C2315100 BXGD017021 Pediatric failure to thrive Pathological Conditions, Signs and Symptoms; Nutritional and Metabolic Diseases; Mental Disorders
C2711227 BXGD017478 Steatohepatitis Digestive System Diseases
C2936476 BXGD018123 Chronic Liver Failure Digestive System Diseases
C3658290 BXGD019256 Drug-Induced Acute Liver Injury Digestive System Diseases; Chemically-Induced Disorders
C3714756 BXGD019429 Intellectual Disability Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
C3887638 BXGD019906 Failure to thrive in infant Pathological Conditions, Signs and Symptoms
C4022857 BXGD021014 Reduced aldolase level
C4024713 BXGD021382 Transient aminoaciduria
C4277682 BXGD022376 Chemical and Drug Induced Liver Injury Digestive System Diseases; Chemically-Induced Disorders
C4279912 BXGD022378 Chemically-Induced Liver Toxicity Digestive System Diseases; Chemically-Induced Disorders
C4554647 BXGD023567 Hypermagnesemia, CTCAE
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0001096 Dihydroxyacetone phosphate 170.06
BXGC0035549 alpha-glycerophosphoric acid 172.01
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein