Showing entry for Galactose-1-phosphate uridylyltransferase


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT006697
Protein NameGalactose-1-phosphate uridylyltransferase
Uniport IdP07902
GeneGALT
Gene Id2592
DomainGalP_UDP_transf; GalP_UDP_tr_C
Pfam PF02744   PF01087  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
1. Metabolism 1.1 Carbohydrate metabolism hsa00052 Galactose metabolism
1. Metabolism 1.1 Carbohydrate metabolism hsa00520 Amino sugar and nucleotide sugar metabolism
1. Metabolism 1.0 Global and overview maps hsa01100 Metabolic pathways
5. Organismal Systems 5.2 Endocrine system hsa04917 Prolactin signaling pathway
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0019388 galactose catabolic process
Biological Process GO:0033499 galactose catabolic process via UDP-galactose
Biological Process GO:0006012 galactose metabolic process
Biological Process GO:0006258 UDP-glucose catabolic process
Biological Process GO:0006011 UDP-glucose metabolic process
molecular function GO:0008108 UDP-glucose:hexose-1-phosphate uridylyltransferase activity
molecular function GO:0008270 zinc ion binding
cellular component GO:0005737 cytoplasm
cellular component GO:0005829 cytosol
cellular component GO:0005794 Golgi apparatus
Reactome
Pathway Id Pathway Name
R-HSA-1430728 Metabolism
R-HSA-1643685 Disease
R-HSA-3781865 Diseases of glycosylation
R-HSA-5609975 Diseases associated with glycosylation precursor biosynthesis
R-HSA-5609978 Defective GALT can cause Galactosemia
R-HSA-5668914 Diseases of metabolism
R-HSA-70370 Galactose catabolism
R-HSA-71387 Metabolism of carbohydrates
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0001925 BXGD000090 Albuminuria Pathological Conditions, Signs and Symptoms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0002878 BXGD000137 Anemia, Hemolytic Hemic and Lymphatic Diseases
C0004134 BXGD000256 Ataxia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0007758 BXGD000475 Cerebellar Ataxia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0011991 BXGD000766 Diarrhea Pathological Conditions, Signs and Symptoms
C0013362 BXGD000817 Dysarthria Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0014175 BXGD000904 Endometriosis Female Urogenital Diseases and Pregnancy Complications
C0015544 BXGD001003 Failure to Thrive Pathological Conditions, Signs and Symptoms
C0016952 BXGD001085 Galactosemias Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Nervous System Diseases
C0019209 BXGD001305 Hepatomegaly Pathological Conditions, Signs and Symptoms; Digestive System Diseases
C0019693 BXGD001346 HIV Infections Infections; Immune System Diseases
C0020615 BXGD001445 Hypoglycemia Nutritional and Metabolic Diseases
C0022346 BXGD001537 Icterus Pathological Conditions, Signs and Symptoms
C0022353 BXGD001539 Neonatal Jaundice Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities
C0023380 BXGD001640 Lethargy Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Behavior and Behavior Mechanisms
C0023890 BXGD001713 Liver Cirrhosis Pathological Conditions, Signs and Symptoms; Digestive System Diseases
C0023895 BXGD001717 Liver diseases Digestive System Diseases
C0023903 BXGD001720 Liver neoplasms Digestive System Diseases; Neoplasms
C0025322 BXGD001863 Premature Menopause Female Urogenital Diseases and Pregnancy Complications
C0025517 BXGD001875 Metabolic Diseases Nutritional and Metabolic Diseases
C0025521 BXGD001876 Inborn Errors of Metabolism Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases
C0026106 BXGD001889 Mild Mental Retardation Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
C0027498 BXGD001994 Nausea and vomiting Pathological Conditions, Signs and Symptoms
C0027651 BXGD002009 Neoplasms Neoplasms
C0029456 BXGD002157 Osteoporosis Nutritional and Metabolic Diseases; Musculoskeletal Diseases
C0040822 BXGD002885 Tremor Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0042963 BXGD003018 Vomiting Pathological Conditions, Signs and Symptoms
C0085215 BXGD003141 Ovarian Failure, Premature Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C0085605 BXGD003200 Liver Failure Digestive System Diseases
C0086543 BXGD003294 Cataract Eye Diseases
C0151639 BXGD003452 Decreased fertility in females Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C0152259 BXGD003576 Cataract secondary to ocular disorder Eye Diseases
C0154208 BXGD003707 Disorder of endocrine ovary Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C0154971 BXGD003761 Presenile cataract Eye Diseases
C0162429 BXGD003942 Malnutrition Nutritional and Metabolic Diseases
C0220981 BXGD004348 Metabolic acidosis Nutritional and Metabolic Diseases
C0232466 BXGD004543 Feeding difficulties
C0232744 BXGD004561 Decreased liver function
C0238621 BXGD004947 Aminoaciduria Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases
C0241210 BXGD005086 Speech Delay Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0243026 BXGD005210 Sepsis Pathological Conditions, Signs and Symptoms; Infections
C0264611 BXGD005403 Apraxia of Phonation Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Behavior and Behavior Mechanisms
C0265428 BXGD005534 Chromosome 9, partial trisomy 9p Pathological Conditions, Signs and Symptoms
C0268151 BXGD005838 Classical galactosemia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Nervous System Diseases
C0268152 BXGD005839 Classical galactosemia, homozygous Duarte-type Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Nervous System Diseases
C0268155 BXGD005840 Deficiency of galactokinase Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Nervous System Diseases
C0268157 BXGD005841 Galactosuria
C0276501 BXGD006427 Human immunodeficiency virus II infection Female Urogenital Diseases and Pregnancy Complications; Infections; Male Urogenital Diseases; Immune System Diseases
C0341858 BXGD007425 Endometriosis of uterus Female Urogenital Diseases and Pregnancy Complications
C0410916 BXGD008452 Neonatal Death Pathological Conditions, Signs and Symptoms; Female Urogenital Diseases and Pregnancy Complications
C0431637 BXGD008697 Mullerian aplasia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases; Endocrine System Diseases
C0521707 BXGD009166 Bilateral cataracts (disorder) Eye Diseases
C0575081 BXGD009512 Gait abnormality Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0596263 BXGD009639 Carcinogenesis Pathological Conditions, Signs and Symptoms; Neoplasms
C0677886 BXGD009734 Epithelial ovarian cancer Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C0747102 BXGD010159 Ovarian failure Endocrine System Diseases
C0750927 BXGD010254 Apraxia, Developmental Verbal Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Behavior and Behavior Mechanisms
C0751161 BXGD010334 UDPglucose 4-epimerase deficiency disease Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Nervous System Diseases
C0854094 BXGD010998 HIV-2 infection Infections; Immune System Diseases
C0919267 BXGD011426 ovarian neoplasm Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C0948896 BXGD011563 Primary hypogonadism Endocrine System Diseases
C1140680 BXGD011718 Malignant neoplasm of ovary Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C1261251 BXGD011851 Agenesis of vagina Congenital, Hereditary, and Neonatal Diseases and Abnormalities
C1262477 BXGD011882 Weight decreased Pathological Conditions, Signs and Symptoms
C1306068 BXGD012354 After-cataract Eye Diseases
C1458140 BXGD013134 Bleeding tendency Hemic and Lymphatic Diseases
C1623038 BXGD013475 Cirrhosis Pathological Conditions, Signs and Symptoms
C1698581 BXGD013519 Rokitansky Kuster Hauser syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases; Endocrine System Diseases
C1857276 BXGD015688 Trichohepatoenteric Syndrome Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Skin and Connective Tissue Diseases
C1865313 BXGD016311 Speech articulation difficulties
C1969073 BXGD016753 Hyperchloremic metabolic acidosis
C2239176 BXGD016965 Liver carcinoma Digestive System Diseases; Neoplasms
C2363741 BXGD017100 HIV-1 infection
C2985280 BXGD018223 Blood Protein Measurement
C3714756 BXGD019429 Intellectual Disability Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
C4021643 BXGD020716 Impairment of galactose metabolism
C4021818 BXGD020804 Abnormality of the ovary
C4023071 BXGD021096 Hypergalactosemia
C4303510 BXGD022563 Idiopathic premature ovarian failure Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C4551915 BXGD023441 Gait Disturbance, CTCAE
C4703627 BXGD023666 Increased level of galactitol in plasma
C4703628 BXGD023667 Increased level of galactitol in urine
C4703629 BXGD023668 Increased level of galactonate in red blood cells
C4703630 BXGD023669 Increased level of galactitol in red blood cells
C4721610 BXGD023760 Carcinoma, Ovarian Epithelial Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C4721766 BXGD023764 Unspecified secondary cataract Eye Diseases
C4732730 BXGD023895 Blood spots
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0040746 glucose-1-phosphate 260.03
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein