adisease

Showing entry for Hyperammonemia

General Disease Information
BXGD Id	BXGD004357
Disease Name	Hyperammonemia
Disease CUI Id	C0220994
MeSH Codes	C23
Disease Class Name	Pathological Conditions, Signs and Symptoms
Semantic Type	Disease or Syndrome
Human Phenotype Ontology Id	HP:0001939
Human Phenotype Ontology Term	Abnormality of metabolism/homeostasis
Disease Ontology Id	DOID:0014667 DOID:630
Disease Ontology Class Name	disease of metabolism; genetic disease
Disorder Network	disorder-protein-compound-food associations

The disease-related target proteins

Proteins

Uniport Id	BXGT Id	Protein Name	Gene	Status	Protein Class
Uniport Id	BXGT Id	Protein name	Gene	Status	Protein class
O43772	BXGT004623	Mitochondrial carnitine/acylcarnitine carrier protein	788	reviewed	Transporter
O76082	BXGT005175	Solute carrier family 22 member 5	6584	reviewed	Transporter
O94925	BXGT005342	Glutaminase kidney isoform, mitochondrial	2744	reviewed	Enzyme
P00367	BXGT005517	Glutamate dehydrogenase 1, mitochondrial	2746	reviewed	Enzyme
P00390	BXGT005526	Glutathione reductase, mitochondrial	2936	reviewed	Enzyme
P00480	BXGT005551	Ornithine carbamoyltransferase, mitochondrial	5009	reviewed
P00505	BXGT005560	Aspartate aminotransferase, mitochondrial	2806	reviewed
P00966	BXGT005707	Argininosuccinate synthase	445	reviewed	Enzyme
P01375	BXGT005753	Tumor necrosis factor	7124	reviewed	Signaling
P01583	BXGT005771	Interleukin-1 alpha	3552	reviewed
P01584	BXGT005772	Interleukin-1 beta	3553	reviewed
P02768	BXGT005955	Serum albumin	213	reviewed	Transporter
P04040	BXGT006132	Catalase	847	reviewed	Enzyme
P04181	BXGT006165	Ornithine aminotransferase, mitochondrial	4942	reviewed	Enzyme
P04424	BXGT006214	Argininosuccinate lyase	435	reviewed	Enzyme
P04818	BXGT006269	Thymidylate synthase	7298	reviewed	Enzyme
P05089	BXGT006310	Arginase-1	383	reviewed	Enzyme
P05165	BXGT006334	Propionyl-CoA carboxylase alpha chain, mitochondrial	5095	reviewed	Enzyme
P05166	BXGT006335	Propionyl-CoA carboxylase beta chain, mitochondrial	5096	reviewed	Enzyme
P06213	BXGT006425	Insulin receptor	3643	reviewed	Kinase
P08183	BXGT006741	ATP-dependent translocase ABCB1	5243	reviewed	Transporter
P08574	BXGT006792	Cytochrome c1, heme protein, mitochondrial	1537	reviewed
P08922	BXGT006843	Proto-oncogene tyrosine-protein kinase ROS	6098	reviewed	Kinase
P11498	BXGT007714	Pyruvate carboxylase, mitochondrial	5091	reviewed	Enzyme
P11509	BXGT007716	Cytochrome P450 2A6	1548	reviewed
P11712	BXGT007738	Cytochrome P450 2C9	1559	reviewed
P12004	BXGT007766	Proliferating cell nuclear antigen	5111	reviewed	Nucleic acid binding
P13236	BXGT007891	C-C motif chemokine 4	6351	reviewed
P15104	BXGT008081	Glutamine synthetase	2752	reviewed	Enzyme
P19438	BXGT008480	Tumor necrosis factor receptor superfamily member 1A	7132	reviewed
P19634	BXGT008504	Sodium/hydrogen exchanger 1	6548	reviewed	Transporter
P22033	BXGT008721	Methylmalonyl-CoA mutase, mitochondrial	4594	reviewed	Enzyme
P23560	BXGT008883	Brain-derived neurotrophic factor	627	reviewed	Signaling
P23786	BXGT008906	Carnitine O-palmitoyltransferase 2, mitochondrial	1376	reviewed	Enzyme
P24752	BXGT008993	Acetyl-CoA acetyltransferase, mitochondrial	38	reviewed	Enzyme
P27708	BXGT009202	CAD protein	790	reviewed	Enzyme
P28482	BXGT009263	Mitogen-activated protein kinase 1	5594	reviewed	Kinase
P31327	BXGT009523	Carbamoyl-phosphate synthase [ammonia], mitochondrial	1373	reviewed	Enzyme
P35218	BXGT009796	Carbonic anhydrase 5A, mitochondrial	763	reviewed
P35222	BXGT009799	Catenin beta-1	1499	reviewed
P35557	BXGT009846	Glucokinase	2645	reviewed	Kinase
P35914	BXGT009880	Hydroxymethylglutaryl-CoA lyase, mitochondrial	3155	reviewed	Enzyme
P41235	BXGT010241	Hepatocyte nuclear factor 4-alpha	3172	reviewed	Nuclear receptor
P42261	BXGT010293	Glutamate receptor 1	2890	reviewed	Ion channel
P42262	BXGT010294	Glutamate receptor 2	2891	reviewed	Ion channel
P46108	BXGT010509	Adapter molecule crk	1398	reviewed
P48728	BXGT010654	Aminomethyltransferase, mitochondrial	275	reviewed
P49411	BXGT010703	Elongation factor Tu, mitochondrial	7284	reviewed	Enzyme
P49748	BXGT010733	Very long-chain specific acyl-CoA dehydrogenase, mitochondrial	37	reviewed	Enzyme
P49841	BXGT010750	Glycogen synthase kinase-3 beta	2932	reviewed	Kinase
P50416	BXGT010797	Carnitine O-palmitoyltransferase 1, liver isoform	1374	reviewed	Enzyme
P50747	BXGT010817	Biotin--protein ligase	3141	reviewed	Enzyme
P54098	BXGT011030	DNA polymerase subunit gamma-1	5428	reviewed	Enzyme
P56556	BXGT011179	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6	4700	reviewed	Enzyme
P78540	BXGT011848	Arginase-2, mitochondrial	384	reviewed	Enzyme
Q04759	BXGT012781	Protein kinase C theta type	5588	reviewed	Kinase
Q09428	BXGT013036	ATP-binding cassette sub-family C member 8	6833	reviewed	Transporter
Q13155	BXGT013320	Aminoacyl tRNA synthase complex-interacting multifunctional protein 2	7965	reviewed
Q16236	BXGT013624	Nuclear factor erythroid 2-related factor 2	4780	reviewed	Enzyme
Q16539	BXGT013634	Mitogen-activated protein kinase 14	1432	reviewed	Kinase
Q16836	BXGT013679	Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial	3033	reviewed
Q5T6L4	BXGT015848	Argininosuccinate synthase 1 isoform 1	445	unreviewed
Q8N159	BXGT018496	N-acetylglutamate synthase, mitochondrial	162417	reviewed
Q96EY8	BXGT019655	Corrinoid adenosyltransferase	326625	reviewed	Enzyme
Q96RI1	BXGT019727	Bile acid receptor	9971	reviewed	Nuclear receptor
Q96RQ3	BXGT019732	Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial	56922	reviewed	Enzyme
Q99714	BXGT019954	3-hydroxyacyl-CoA dehydrogenase type-2	3028	reviewed	Enzyme
Q9HCC0	BXGT020530	Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial	64087	reviewed	Enzyme
Q9UJS0	BXGT021727	Calcium-binding mitochondrial carrier protein Aralar2	10165	reviewed	Transporter
Q9Y619	BXGT022316	Mitochondrial ornithine transporter 1	10166	reviewed	Transporter
P09622	BXGT023116	Dihydrolipoyl dehydrogenase, mitochondrial	1738	reviewed	Enzyme
O14793	BXGT023280	Growth/differentiation factor 8	2660	reviewed	Signaling

The disease-related compounds

Compounds

BXGC Id	Compound Name	Structure	Molecular Weight	Number of targets^{?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease}

The disease-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compounds in food^{?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease}