adisease

Showing entry for Lipoatrophy

General Disease Information
BXGD Id	BXGD012125
Disease Name	Lipoatrophy
Disease CUI Id	C1280433
MeSH Codes	C18 C17
Disease Class Name	Nutritional and Metabolic Diseases; Skin and Connective Tissue Diseases
Semantic Type	Disease or Syndrome
Human Phenotype Ontology Id	HP:0003549
Human Phenotype Ontology Term	Abnormality of connective tissue
Disease Ontology Id
Disease Ontology Class Name
Disorder Network	disorder-protein-compound-food associations

The disease-related target proteins

Proteins

Uniport Id	BXGT Id	Protein Name	Gene	Status	Protein Class
Uniport Id	BXGT Id	Protein name	Gene	Status	Protein class
O15120	BXGT004129	1-acyl-sn-glycerol-3-phosphate acyltransferase beta	10555	reviewed
O43293	BXGT004584	Death-associated protein kinase 3	1613	reviewed	Kinase
O60240	BXGT004860	Perilipin-1	5346	reviewed
O60706	BXGT004896	ATP-binding cassette sub-family C member 9	10060	reviewed	Transporter
O75112	BXGT005099	LIM domain-binding protein 3	11155	reviewed	Cellular structure
O75844	BXGT005156	CAAX prenyl protease 1 homolog	10269	reviewed	Enzyme
P01100	BXGT005727	Proto-oncogene c-Fos	2353	reviewed	Transcription factor
P01308	BXGT005749	Insulin	3630	reviewed
P01375	BXGT005753	Tumor necrosis factor	7124	reviewed	Signaling
P01583	BXGT005771	Interleukin-1 alpha	3552	reviewed
P02461	BXGT005880	Collagen alpha-1(III) chain	1281	reviewed
P02511	BXGT005885	Alpha-crystallin B chain	1410	reviewed
P02545	BXGT005889	Prelamin-A/C	4000	reviewed
P02649	BXGT005909	Apolipoprotein E	348	reviewed
P02656	BXGT005913	Apolipoprotein C-III	345	reviewed
P03372	BXGT006059	Estrogen receptor	2099	reviewed	Nuclear receptor
P04049	BXGT006133	RAF proto-oncogene serine/threonine-protein kinase	5894	reviewed	Kinase
P04066	BXGT006142	Tissue alpha-L-fucosidase	2517	reviewed
P06213	BXGT006425	Insulin receptor	3643	reviewed	Kinase
P08235	BXGT006751	Mineralocorticoid receptor	4306	reviewed	Nuclear receptor
P09493	BXGT006900	Tropomyosin alpha-1 chain	7168	reviewed	Cellular structure
P09619	BXGT006911	Platelet-derived growth factor receptor beta	5159	reviewed	Kinase
P10145	BXGT007542	Interleukin-8	3576	reviewed	Signaling
P16871	BXGT008269	Interleukin-7 receptor subunit alpha	3575	reviewed	Receptor
P18206	BXGT008389	Vinculin	7414	reviewed
P19429	BXGT008479	Troponin I, cardiac muscle	7137	reviewed	Cellular structure
P21333	BXGT008638	Filamin-A	2316	reviewed
P27986	BXGT009216	Phosphatidylinositol 3-kinase regulatory subunit alpha	5295	reviewed	Kinase
P28907	BXGT009301	ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1	952	reviewed	Enzyme
P31040	BXGT009503	Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial	6389	reviewed	Enzyme
P35555	BXGT009845	Fibrillin-1	2200	reviewed	Calcium-binding protein
P36021	BXGT009893	Monocarboxylate transporter 8	6567	reviewed	Transporter
P36956	BXGT009947	Sterol regulatory element-binding protein 1	6720	reviewed
P37231	BXGT009972	Peroxisome proliferator-activated receptor gamma	5468	reviewed	Nuclear receptor
P42336	BXGT010302	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	5290	reviewed	Kinase
P45379	BXGT010459	Troponin T, cardiac muscle	7139	reviewed	Cellular structure
P49768	BXGT010740	Presenilin-1	5663	reviewed	Enzyme
P49810	BXGT010747	Presenilin-2	5664	reviewed	Enzyme
P55265	BXGT011117	Double-stranded RNA-specific adenosine deaminase	103	reviewed	Enzyme
P60709	BXGT011322	Actin, cytoplasmic 1	60	reviewed	Cellular structure
P63316	BXGT011517	Troponin C, slow skeletal and cardiac muscles	7134	reviewed	Calcium-binding protein
Q14116	BXGT013442	Interleukin-18	3606	reviewed
Q14126	BXGT013446	Desmoglein-2	1829	reviewed	Cell adhesion
Q14191	BXGT013452	Werner syndrome ATP-dependent helicase	7486	reviewed	Enzyme
Q14524	BXGT013478	Sodium channel protein type 5 subunit alpha	6331	reviewed	Ion channel
Q15848	BXGT013609	Adiponectin	9370	reviewed
Q30201	BXGT014297	Hereditary hemochromatosis protein	3077	reviewed
Q6NUK1	BXGT016429	Calcium-binding mitochondrial carrier protein SCaMC-1	29957	reviewed	Transporter
Q8WZ42	BXGT019023	Titin	7273	reviewed	Kinase
Q92731	BXGT019366	Estrogen receptor beta	2100	reviewed	Nuclear receptor
Q96AC1	BXGT019617	Fermitin family homolog 2	10979	reviewed
Q9NNW7	BXGT021139	Thioredoxin reductase 2, mitochondrial	10587	reviewed	Enzyme
Q9Y3Z3	BXGT022268	Deoxynucleoside triphosphate triphosphohydrolase SAMHD1	25939	reviewed
O14490	BXGT023570	Disks large-associated protein 1	9229	reviewed	Receptor
O95140	BXGT024482	Mitofusin-2	9927	reviewed	Enzyme

The disease-related compounds

Compounds

BXGC Id	Compound Name	Structure	Molecular Weight	Number of targets^{?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease}

The disease-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compounds in food^{?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease}