Showing entry for Penile hypospadias


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Disease Information
BXGD IdBXGD013491
Disease NamePenile hypospadias
Disease CUI IdC1691215
MeSH Codes C16   C13   C12  
Disease Class NameCongenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
Semantic TypeCongenital Abnormality
Human Phenotype Ontology Id HP:0000119  
Human Phenotype Ontology TermAbnormality of the genitourinary system
Disease Ontology Id   
Disease Ontology Class Name
Disorder Network disorder-protein-compound-food associations
The  disease-related  target proteins
Proteins
Uniport Id BXGT Id Protein Name Gene Status Protein Class
Uniport Id BXGT Id Protein name Gene Status Protein class
O00329 BXGT003909 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform 5293 reviewed Kinase
O15230 BXGT004138 Laminin subunit alpha-5 3911 reviewed Enzyme modulator
O43854 BXGT004630 EGF-like repeat and discoidin I-like domain-containing protein 3 10085 reviewed Enzyme
O94811 BXGT005336 Tubulin polymerization-promoting protein 11076 reviewed Cellular structure
O94907 BXGT005340 Dickkopf-related protein 1 22943 reviewed
P00441 BXGT005540 Superoxide dismutase [Cu-Zn] 6647 reviewed Enzyme
P01100 BXGT005727 Proto-oncogene c-Fos 2353 reviewed Transcription factor
P01137 BXGT005737 Transforming growth factor beta-1 proprotein 7040 reviewed Signaling
P03372 BXGT006059 Estrogen receptor 2099 reviewed Nuclear receptor
P04798 BXGT006265 Cytochrome P450 1A1 1543 reviewed Enzyme
P05093 BXGT006313 Steroid 17-alpha-hydroxylase/17,20 lyase 1586 reviewed
P05108 BXGT006317 Cholesterol side-chain cleavage enzyme, mitochondrial 1583 reviewed
P05412 BXGT006354 Transcription factor AP-1 3725 reviewed Transcription factor
P08842 BXGT006830 Steryl-sulfatase 412 reviewed Enzyme
P09488 BXGT006899 Glutathione S-transferase Mu 1 2944 reviewed
P10275 BXGT007552 Androgen receptor 367 reviewed Nuclear receptor
P11511 BXGT007717 Aromatase 1588 reviewed Enzyme
P12273 BXGT007787 Prolactin-inducible protein 5304 reviewed
P16070 BXGT008186 CD44 antigen 960 reviewed
P16234 BXGT008209 Platelet-derived growth factor receptor alpha 5156 reviewed Kinase
P18075 BXGT008375 Bone morphogenetic protein 7 655 reviewed Signaling
P18405 BXGT008400 3-oxo-5-alpha-steroid 4-dehydrogenase 1 6715 reviewed Enzyme
P18847 BXGT008431 Cyclic AMP-dependent transcription factor ATF-3 467 reviewed Transcription factor
P19544 BXGT008494 Wilms tumor protein 7490 reviewed Nucleic acid binding
P20813 BXGT008603 Cytochrome P450 2B6 1555 reviewed
P21802 BXGT008691 Fibroblast growth factor receptor 2 2263 reviewed Kinase
P30711 BXGT009460 Glutathione S-transferase theta-1 2952 reviewed
P31213 BXGT009515 3-oxo-5-alpha-steroid 4-dehydrogenase 2 6716 reviewed Enzyme
P31749 BXGT009574 RAC-alpha serine/threonine-protein kinase 207 reviewed Kinase
P35869 BXGT009877 Aryl hydrocarbon receptor 196 reviewed Transcription factor
P36897 BXGT009941 TGF-beta receptor type-1 7046 reviewed Kinase
P37058 BXGT009956 Testosterone 17-beta-dehydrogenase 3 3293 reviewed
P37173 BXGT009970 TGF-beta receptor type-2 7048 reviewed Kinase
P40763 BXGT010202 Signal transducer and activator of transcription 3 6774 reviewed Nucleic acid binding
P42330 BXGT010301 Aldo-keto reductase family 1 member C3 8644 reviewed Enzyme
P42336 BXGT010302 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform 5290 reviewed Kinase
P42338 BXGT010303 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform 5291 reviewed Kinase
P42898 BXGT010344 Methylenetetrahydrofolate reductase 4524 reviewed
P45983 BXGT010494 Mitogen-activated protein kinase 8 5599 reviewed Kinase
P45984 BXGT010495 Mitogen-activated protein kinase 9 5601 reviewed Kinase
P48736 BXGT010658 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform 5294 reviewed Kinase
P56937 BXGT011205 3-keto-steroid reductase 51478 reviewed
Q02790 BXGT012672 Peptidyl-prolyl cis-trans isomerase FKBP4 2288 reviewed Enzyme
Q13233 BXGT013330 Mitogen-activated protein kinase kinase kinase 1 4214 reviewed Kinase
Q13285 BXGT013335 Steroidogenic factor 1 2516 reviewed Nuclear receptor
Q13627 BXGT013385 Dual specificity tyrosine-phosphorylation-regulated kinase 1A 1859 reviewed Kinase
Q14289 BXGT013459 Protein-tyrosine kinase 2-beta 2185 reviewed Kinase
Q14849 BXGT013510 StAR-related lipid transfer protein 3 10948 reviewed
Q15465 BXGT013573 Sonic hedgehog protein 6469 reviewed
Q15637 BXGT013586 Splicing factor 1 7536 reviewed Nucleic acid binding
Q16236 BXGT013624 Nuclear factor erythroid 2-related factor 2 4780 reviewed Enzyme
Q16678 BXGT013656 Cytochrome P450 1B1 1545 reviewed Enzyme
Q6UWP2 BXGT016567 Dehydrogenase/reductase SDR family member 11 79154 reviewed Enzyme
Q86YC2 BXGT017633 Partner and localizer of BRCA2 79728 reviewed
Q8IWS0 BXGT018356 PHD finger protein 6 84295 reviewed Nucleic acid binding
Q8NCC3 BXGT018546 Group XV phospholipase A2 23659 reviewed Enzyme
Q92731 BXGT019366 Estrogen receptor beta 2100 reviewed Nuclear receptor
Q9NZJ5 BXGT021275 Eukaryotic translation initiation factor 2-alpha kinase 3 9451 reviewed Kinase
Q9UHX1 BXGT021707 Poly(U)-binding-splicing factor PUF60 22827 reviewed
Q9UJ71 BXGT021725 C-type lectin domain family 4 member K 50489 reviewed Receptor
Q5KSL6 BXGT022671 Diacylglycerol kinase kappa 139189 reviewed Enzyme
P17535 BXGT023437 Transcription factor jun-D 3727 reviewed Transcription factor
P53539 BXGT023438 Protein fosB 2354 reviewed Transcription factor
Q86SQ9 BXGT025875 Dehydrodolichyl diphosphate synthase complex subunit DHDDS 79947 reviewed Enzyme
The  disease-related  compounds
Compounds
BXGC Id Compound Name Structure Molecular Weight Number of targets?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease
The  disease-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compounds in food?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease