Showing entry for Group XV phospholipase A2


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT018546
Protein NameGroup XV phospholipase A2
Uniport IdQ8NCC3
GenePLA2G15
Gene Id23659
DomainLCAT
Pfam PF02450  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
1. Metabolism 1.3 Lipid metabolism hsa00564 Glycerophospholipid metabolism
4. Cellular Processes 4.1 Transport and catabolism hsa04142 Lysosome
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0006672 ceramide metabolic process
Biological Process GO:0006651 diacylglycerol biosynthetic process
Biological Process GO:0009062 fatty acid catabolic process
Biological Process GO:0006650 glycerophospholipid metabolic process
Biological Process GO:0034638 phosphatidylcholine catabolic process
Biological Process GO:0046338 phosphatidylethanolamine catabolic process
Biological Process GO:0006644 phospholipid metabolic process
molecular function GO:0052740 1-acyl-2-lysophosphatidylserine acylhydrolase activity
molecular function GO:0016411 acylglycerol O-acyltransferase activity
molecular function GO:0047499 calcium-independent phospholipase A2 activity
molecular function GO:0004622 lysophospholipase activity
molecular function GO:0008374 O-acyltransferase activity
molecular function GO:0102545 phosphatidyl phospholipase B activity
molecular function GO:0052739 phosphatidylserine 1-acylhydrolase activity
molecular function GO:0008970 phospholipase A1 activity
molecular function GO:0102567 phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine)
molecular function GO:0102568 phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine)
molecular function GO:0005543 phospholipid binding
cellular component GO:0070062 extracellular exosome
cellular component GO:0005576 extracellular region
cellular component GO:0005615 extracellular space
cellular component GO:0043231 intracellular membrane-bounded organelle
cellular component GO:0005764 lysosome
cellular component GO:0016020 membrane
cellular component GO:0005654 nucleoplasm
Reactome
Pathway Id Pathway Name
R-HSA-1430728 Metabolism
R-HSA-1483115 Hydrolysis of LPC
R-HSA-1483206 Glycerophospholipid biosynthesis
R-HSA-1483257 Phospholipid metabolism
R-HSA-556833 Metabolism of lipids
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0000768 BXGD000007 Congenital Abnormality Congenital, Hereditary, and Neonatal Diseases and Abnormalities
C0000833 BXGD000014 Abscess Pathological Conditions, Signs and Symptoms; Infections
C0001175 BXGD000029 Acquired Immunodeficiency Syndrome Infections; Immune System Diseases
C0002395 BXGD000111 Alzheimer's Disease Nervous System Diseases; Mental Disorders
C0003504 BXGD000202 Aortic Valve Insufficiency Cardiovascular Diseases
C0003615 BXGD000212 Appendicitis Digestive System Diseases; Infections
C0003850 BXGD000225 Arteriosclerosis Cardiovascular Diseases
C0003869 BXGD000234 Arthritis, Infectious Infections; Musculoskeletal Diseases
C0004153 BXGD000260 Atherosclerosis Cardiovascular Diseases
C0004238 BXGD000262 Atrial Fibrillation Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0004936 BXGD000295 Mental disorders Mental Disorders
C0006142 BXGD000374 Malignant neoplasm of breast Neoplasms; Skin and Connective Tissue Diseases
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0007102 BXGD000425 Malignant tumor of colon Digestive System Diseases; Neoplasms
C0007103 BXGD000426 Malignant neoplasm of endometrium Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0007107 BXGD000428 Malignant neoplasm of larynx Neoplasms; Respiratory Tract Diseases; Otorhinolaryngologic Diseases
C0007113 BXGD000430 Rectal Carcinoma Digestive System Diseases; Neoplasms
C0007134 BXGD000443 Renal Cell Carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0007222 BXGD000454 Cardiovascular Diseases Cardiovascular Diseases
C0008031 BXGD000511 Chest Pain Pathological Conditions, Signs and Symptoms
C0009402 BXGD000605 Colorectal Carcinoma Digestive System Diseases; Neoplasms
C0010046 BXGD000645 Corn of toe Skin and Connective Tissue Diseases
C0010051 BXGD000646 Coronary Aneurysm Cardiovascular Diseases
C0010054 BXGD000647 Coronary Arteriosclerosis Cardiovascular Diseases
C0010068 BXGD000648 Coronary heart disease Cardiovascular Diseases
C0010346 BXGD000664 Crohn Disease Digestive System Diseases
C0011127 BXGD000699 Pressure Ulcer Skin and Connective Tissue Diseases
C0011175 BXGD000701 Dehydration Pathological Conditions, Signs and Symptoms; Nutritional and Metabolic Diseases
C0011206 BXGD000703 Delirium Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
C0011570 BXGD000729 Mental Depression Behavior and Behavior Mechanisms
C0011581 BXGD000733 Depressive disorder Mental Disorders
C0011847 BXGD000749 Diabetes Endocrine System Diseases
C0011849 BXGD000751 Diabetes Mellitus Nutritional and Metabolic Diseases; Endocrine System Diseases
C0011881 BXGD000760 Diabetic Nephropathy Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases; Endocrine System Diseases
C0013146 BXGD000801 Drug abuse Chemically-Induced Disorders; Mental Disorders
C0014742 BXGD000945 Erythema Multiforme Skin and Connective Tissue Diseases
C0014852 BXGD000958 Esophageal Diseases Digestive System Diseases
C0014859 BXGD000961 Esophageal Neoplasms Digestive System Diseases; Neoplasms
C0014867 BXGD000964 Esophageal Varices Digestive System Diseases
C0015672 BXGD001011 Fatigue Pathological Conditions, Signs and Symptoms
C0016065 BXGD001046 Polyostotic fibrous dysplasia Musculoskeletal Diseases
C0016169 BXGD001048 pathologic fistula Pathological Conditions, Signs and Symptoms
C0017086 BXGD001091 Gangrene Pathological Conditions, Signs and Symptoms
C0018790 BXGD001221 Cardiac Arrest Cardiovascular Diseases
C0018799 BXGD001224 Heart Diseases Cardiovascular Diseases
C0018802 BXGD001227 Congestive heart failure Cardiovascular Diseases
C0019322 BXGD001317 Umbilical hernia Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications
C0020443 BXGD001385 Hypercholesterolemia Nutritional and Metabolic Diseases
C0020445 BXGD001386 Hypercholesterolemia, Familial Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases
C0020538 BXGD001422 Hypertensive disease Cardiovascular Diseases
C0020625 BXGD001451 Hyponatremia Nutritional and Metabolic Diseases
C0021390 BXGD001503 Inflammatory Bowel Diseases Digestive System Diseases
C0023449 BXGD001650 Acute lymphocytic leukemia Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0023452 BXGD001651 Childhood Acute Lymphoblastic Leukemia Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0024117 BXGD001734 Chronic Obstructive Airway Disease Respiratory Tract Diseases
C0027051 BXGD001963 Myocardial Infarction Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0027651 BXGD002009 Neoplasms Neoplasms
C0028754 BXGD002082 Obesity Pathological Conditions, Signs and Symptoms; Nutritional and Metabolic Diseases
C0030193 BXGD002191 Pain Pathological Conditions, Signs and Symptoms
C0030297 BXGD002204 Pancreatic Neoplasm Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0032285 BXGD002344 Pneumonia Infections; Respiratory Tract Diseases
C0034155 BXGD002468 Purpura, Thrombotic Thrombocytopenic Pathological Conditions, Signs and Symptoms; Hemic and Lymphatic Diseases
C0035078 BXGD002505 Kidney Failure Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0036341 BXGD002600 Schizophrenia Mental Disorders
C0036690 BXGD002632 Septicemia Pathological Conditions, Signs and Symptoms; Infections
C0037930 BXGD002714 Spinal Cord Neoplasms Neoplasms; Nervous System Diseases
C0037939 BXGD002716 Spinal Neoplasms Neoplasms; Musculoskeletal Diseases
C0038016 BXGD002727 Spondylolisthesis Musculoskeletal Diseases
C0038017 BXGD002728 Congenital spondylolisthesis Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0038454 BXGD002760 Cerebrovascular accident Nervous System Diseases; Cardiovascular Diseases
C0039103 BXGD002791 Synovitis Musculoskeletal Diseases
C0042029 BXGD002951 Urinary tract infection Female Urogenital Diseases and Pregnancy Complications; Infections; Male Urogenital Diseases
C0042164 BXGD002965 Uveitis Eye Diseases
C0042582 BXGD002993 Vesicovaginal Fistula Pathological Conditions, Signs and Symptoms; Female Urogenital Diseases and Pregnancy Complications
C0085693 BXGD003241 Acute appendicitis NOS (disorder) Digestive System Diseases; Infections
C0086132 BXGD003264 Depressive Symptoms Behavior and Behavior Mechanisms
C0086447 BXGD003286 Ileal Pouches
C0149520 BXGD003327 Acute Cholecystitis Digestive System Diseases
C0149871 BXGD003375 Deep Vein Thrombosis Cardiovascular Diseases
C0152018 BXGD003518 Esophageal carcinoma Digestive System Diseases; Neoplasms
C0155626 BXGD003806 Acute myocardial infarction Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0162871 BXGD003996 Aortic Aneurysm, Abdominal Cardiovascular Diseases
C0178874 BXGD004037 Tumor Progression Pathological Conditions, Signs and Symptoms
C0201657 BXGD004051 C-reactive protein measurement
C0202117 BXGD004074 Low density lipoprotein cholesterol measurement
C0202236 BXGD004086 Triglycerides measurement
C0205944 BXGD004141 Sarcoma, Epithelioid Neoplasms
C0206754 BXGD004289 Neuroendocrine Tumors Neoplasms
C0220668 BXGD004317 Congenital contractural arachnodactyly Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0239981 BXGD005011 Hypoalbuminemia Hemic and Lymphatic Diseases
C0242350 BXGD005154 Erectile dysfunction Male Urogenital Diseases; Mental Disorders
C0242363 BXGD005156 Islet Cell Tumor Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0243026 BXGD005210 Sepsis Pathological Conditions, Signs and Symptoms; Infections
C0264714 BXGD005416 Acute heart failure Cardiovascular Diseases
C0265706 BXGD005570 Gastroschisis Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0267725 BXGD005768 Paraesophageal hernia Pathological Conditions, Signs and Symptoms
C0278498 BXGD006521 Malignant neoplasm of stomach stage IV
C0279702 BXGD006685 Conventional (Clear Cell) Renal Cell Carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0281361 BXGD006774 Adenocarcinoma of pancreas Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0302142 BXGD006831 Deformity Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities
C0311269 BXGD006872 Irreducible ventral hernia Pathological Conditions, Signs and Symptoms
C0332853 BXGD006901 Anastomosis
C0340288 BXGD007316 Stable angina Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0340643 BXGD007357 Dissection of aorta Cardiovascular Diseases
C0344315 BXGD007666 Depressed mood Behavior and Behavior Mechanisms
C0346957 BXGD007836 Disseminated Malignant Neoplasm Neoplasms
C0375553 BXGD007979 Continuous leakage of urine Pathological Conditions, Signs and Symptoms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0376358 BXGD007992 Malignant neoplasm of prostate Neoplasms; Male Urogenital Diseases
C0392885 BXGD008071 High density lipoprotein measurement
C0410698 BXGD008446 Neuromuscular scoliosis Musculoskeletal Diseases
C0428472 BXGD008630 Serum HDL cholesterol measurement
C0428474 BXGD008631 Serum LDL cholesterol measurement
C0476089 BXGD008977 Endometrial Carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0520679 BXGD009101 Sleep Apnea, Obstructive Respiratory Tract Diseases; Nervous System Diseases
C0546837 BXGD009343 Malignant neoplasm of esophagus Digestive System Diseases; Neoplasms
C0553580 BXGD009399 Ewings sarcoma Neoplasms
C0575157 BXGD009514 Deformity of spine
C0585129 BXGD009584 Retroperitoneal sarcoma Neoplasms
C0595921 BXGD009626 Intraocular pressure disorder Eye Diseases
C0595989 BXGD009632 Carcinoma of larynx Neoplasms; Respiratory Tract Diseases; Otorhinolaryngologic Diseases
C0600139 BXGD009695 Prostate carcinoma Neoplasms; Male Urogenital Diseases
C0678222 BXGD009749 Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C0687720 BXGD009844 Central Diabetes Insipidus Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases; Endocrine System Diseases
C0699790 BXGD009866 Colon Carcinoma Digestive System Diseases; Neoplasms
C0701818 BXGD009903 Choledocholithiasis Digestive System Diseases
C0742343 BXGD010061 Acute Chest Syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Respiratory Tract Diseases; Hemic and Lymphatic Diseases
C0745103 BXGD010114 Hyperlipoproteinemia Type IIa Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases
C0750151 BXGD010228 Vaso-Occlusive Crisis Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Hemic and Lymphatic Diseases
C0751177 BXGD010338 Cancer of Head Neoplasms
C0751571 BXGD010505 Cancer of Urinary Tract Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0751606 BXGD010523 Adult Acute Lymphocytic Leukemia
C0848558 BXGD010882 Hypospadias Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0853879 BXGD010982 Invasive carcinoma of breast Neoplasms; Skin and Connective Tissue Diseases
C0854119 BXGD011001 Ruptured Appendicitis Digestive System Diseases; Infections
C0878552 BXGD011369 Coronary artery ectasia
C0948008 BXGD011499 Ischemic stroke Nervous System Diseases; Cardiovascular Diseases
C0948089 BXGD011504 Acute Coronary Syndrome Cardiovascular Diseases
C1145670 BXGD011764 Respiratory Failure Respiratory Tract Diseases
C1269955 BXGD012005 Tumor Cell Invasion
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C1306503 BXGD012363 Congenital exomphalos Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities
C1337011 BXGD012874 Well Differentiated Pancreatic Endocrine Tumor Digestive System Diseases; Neoplasms; Endocrine System Diseases
C1536220 BXGD013341 ST segment elevation myocardial infarction Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C1561643 BXGD013363 Chronic Kidney Diseases Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C1561826 BXGD013364 Overweight and obesity
C1561921 BXGD013366 Non-ST elevation (NSTEMI) myocardial infarction
C1691215 BXGD013491 Penile hypospadias Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C1692886 BXGD013495 Arthritis, Bacterial Infections; Musculoskeletal Diseases
C1704272 BXGD013537 Benign Prostatic Hyperplasia Male Urogenital Diseases
C1704436 BXGD013564 Peripheral Arterial Diseases Cardiovascular Diseases
C1839454 BXGD014375 PROPERDIN DEFICIENCY, X-LINKED Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Immune System Diseases
C1852540 BXGD015290 Coronary Artery Dissection, Spontaneous Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Cardiovascular Diseases
C1861172 BXGD016016 Venous Thromboembolism Cardiovascular Diseases
C1956346 BXGD016627 Coronary Artery Disease Cardiovascular Diseases
C2239176 BXGD016965 Liver carcinoma Digestive System Diseases; Neoplasms
C2609176 BXGD017168 Kounis Syndrome Immune System Diseases; Cardiovascular Diseases
C2919828 BXGD017881 Chronic ulcerative colitis Digestive System Diseases
C3160886 BXGD018488 Non ST segment elevation acute coronary syndrome
C3266262 BXGD018600 Multiple Chronic Conditions Pathological Conditions, Signs and Symptoms
C3278509 BXGD018742 Spinal fusion
C3496069 BXGD019017 cocaine use
C3887662 BXGD019914 Intraspinal Neoplasm Neoplasms; Musculoskeletal Diseases; Nervous System Diseases
C4020969 BXGD020517 Inflammatory abnormality of the eye
C4049446 BXGD021933 Neointimal hyperplasia
C4255010 BXGD022310 Non-ST Elevated Myocardial Infarction Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C4290140 BXGD022508 recurrent myocardial infarction
C4528257 BXGD023159 Corpuscular Hemoglobin Concentration Mean
C4546318 BXGD023295 Organ surgical site infection
C4721772 BXGD023767 Postoperative delirium Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
C4722085 BXGD023788 Malignant neoplasm of colon and/or rectum
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0003705 Chloride 35.45
BXGC0018397 beta-1,4-mannan 180.06
BXGC0037687 (4S)-2-methylpentane-2,4-diol 118.1
BXGC0047449 Ester of phospholipid 645.38
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein