adisease

Showing entry for Overgrowth

General Disease Information
BXGD Id	BXGD015028
Disease Name	Overgrowth
Disease CUI Id	C1849265
MeSH Codes
Disease Class Name
Semantic Type	Finding
Human Phenotype Ontology Id	HP:0001507
Human Phenotype Ontology Term	Growth abnormality
Disease Ontology Id
Disease Ontology Class Name
Disorder Network	disorder-protein-compound-food associations

The disease-related target proteins

Proteins

Uniport Id	BXGT Id	Protein Name	Gene	Status	Protein Class
Uniport Id	BXGT Id	Protein name	Gene	Status	Protein class
A0A024RAV5	BXGT000013	V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog, isoform CRA_b	3845	unreviewed
O00571	BXGT003938	ATP-dependent RNA helicase DDX3X	1654	reviewed
O15553	BXGT004181	Pyrin	4210	reviewed
O60706	BXGT004896	ATP-binding cassette sub-family C member 9	10060	reviewed	Transporter
O75530	BXGT005135	Polycomb protein EED	8726	reviewed
P00439	BXGT005539	Phenylalanine-4-hydroxylase	5053	reviewed
P01111	BXGT005731	GTPase NRas	4893	reviewed	Enzyme modulator
P01112	BXGT005732	GTPase HRas	3265	reviewed	Enzyme modulator
P01116	BXGT005733	GTPase KRas	3845	reviewed	Enzyme modulator
P03372	BXGT006059	Estrogen receptor	2099	reviewed	Nuclear receptor
P06865	BXGT006516	Beta-hexosaminidase subunit alpha	3073	reviewed	Enzyme
P09619	BXGT006911	Platelet-derived growth factor receptor beta	5159	reviewed	Kinase
P11166	BXGT007661	Solute carrier family 2, facilitated glucose transporter member 1	6513	reviewed	Transporter
P14867	BXGT008061	Gamma-aminobutyric acid receptor subunit alpha-1	2554	reviewed	Ion channel
P20930	BXGT008616	Filaggrin	2312	reviewed	Cellular structure
P21359	BXGT008640	Neurofibromin	4763	reviewed	Enzyme modulator
P21802	BXGT008691	Fibroblast growth factor receptor 2	2263	reviewed	Kinase
P23526	BXGT008878	Adenosylhomocysteinase	191	reviewed	Enzyme
P23560	BXGT008883	Brain-derived neurotrophic factor	627	reviewed	Signaling
P30279	BXGT009415	G1/S-specific cyclin-D2	894	reviewed	Enzyme modulator
P30518	BXGT009428	Vasopressin V2 receptor	554	reviewed	G-protein coupled receptor
P31040	BXGT009503	Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial	6389	reviewed	Enzyme
P35222	BXGT009799	Catenin beta-1	1499	reviewed
P35498	BXGT009838	Sodium channel protein type 1 subunit alpha	6323	reviewed	Ion channel
P35555	BXGT009845	Fibrillin-1	2200	reviewed	Calcium-binding protein
P35557	BXGT009846	Glucokinase	2645	reviewed	Kinase
P41229	BXGT010239	Lysine-specific demethylase 5C	8242	reviewed
P42336	BXGT010302	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	5290	reviewed	Kinase
P49419	BXGT010705	Alpha-aminoadipic semialdehyde dehydrogenase	501	reviewed	Enzyme
P50993	BXGT010826	Sodium/potassium-transporting ATPase subunit alpha-2	477	reviewed	Transporter
P51649	BXGT010872	Succinate-semialdehyde dehydrogenase, mitochondrial	7915	reviewed	Enzyme
P51787	BXGT010889	Potassium voltage-gated channel subfamily KQT member 1	3784	reviewed	Ion channel
P54278	BXGT011038	Mismatch repair endonuclease PMS2	5395	reviewed	Nucleic acid binding
P55201	BXGT011109	Peregrin	7862	reviewed
P60484	BXGT011307	Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN	5728	reviewed	Enzyme
P63092	BXGT011495	Guanine nucleotide-binding protein G(s) subunit alpha isoforms short	2778	reviewed
P98160	BXGT012228	Basement membrane-specific heparan sulfate proteoglycan core protein	3339	reviewed	Enzyme modulator
Q03164	BXGT012700	Histone-lysine N-methyltransferase 2A	4297	reviewed
Q12809	BXGT013267	Potassium voltage-gated channel subfamily H member 2	3757	reviewed	Ion channel
Q13233	BXGT013330	Mitogen-activated protein kinase kinase kinase 1	4214	reviewed	Kinase
Q13402	BXGT013348	Unconventional myosin-VIIa	4647	reviewed	Cellular structure
Q13509	BXGT013366	Tubulin beta-3 chain	10381	reviewed	Cellular structure
Q15022	BXGT013523	Polycomb protein SUZ12	23512	reviewed	Nucleic acid binding
Q15858	BXGT013610	Sodium channel protein type 9 subunit alpha	6335	reviewed	Ion channel
Q15910	BXGT013612	Histone-lysine N-methyltransferase EZH2	2146	reviewed	Epigenetic regulator
Q9BYW2	BXGT020192	Histone-lysine N-methyltransferase SETD2	29072	reviewed	Epigenetic regulator
Q9UPY3	BXGT021802	Endoribonuclease Dicer	23405	reviewed	Enzyme
Q9Y6K1	BXGT022331	DNA (cytosine-5)-methyltransferase 3A	1788	reviewed
Q96L73	BXGT024676	Histone-lysine N-methyltransferase, H3 lysine-36 specific	64324	reviewed	Epigenetic regulator
Q13635	BXGT024910	Protein patched homolog 1	5727	reviewed
P51608	BXGT025073	Methyl-CpG-binding protein 2	4204	reviewed	Epigenetic regulator

The disease-related compounds

Compounds

BXGC Id	Compound Name	Structure	Molecular Weight	Number of targets^{?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease}

The disease-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compounds in food^{?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease}