Showing entry for Sarcoma of soft tissue


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Disease Information
BXGD IdBXGD023392
Disease NameSarcoma of soft tissue
Disease CUI IdC4551687
MeSH Codes C04  
Disease Class NameNeoplasms
Semantic TypeNeoplastic Process
Human Phenotype Ontology Id HP:0002664  
Human Phenotype Ontology TermNeoplasm
Disease Ontology Id   
Disease Ontology Class Name
Disorder Network disorder-protein-compound-food associations
The  disease-related  target proteins
Proteins
Uniport Id BXGT Id Protein Name Gene Status Protein Class
Uniport Id BXGT Id Protein name Gene Status Protein class
A0A024RAV5 BXGT000013 V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog, isoform CRA_b 3845 unreviewed
O14733 BXGT004087 Dual specificity mitogen-activated protein kinase kinase 7 5609 reviewed Kinase
O14746 BXGT004091 Telomerase reverse transcriptase 7015 reviewed Enzyme
O14757 BXGT004092 Serine/threonine-protein kinase Chk1 1111 reviewed Kinase
O15151 BXGT004132 Protein Mdm4 4194 reviewed Nucleic acid binding
O15438 BXGT004168 Canalicular multispecific organic anion transporter 2 8714 reviewed Transporter
O60240 BXGT004860 Perilipin-1 5346 reviewed
O75030 BXGT005096 Microphthalmia-associated transcription factor 4286 reviewed
O75473 BXGT005129 Leucine-rich repeat-containing G-protein coupled receptor 5 8549 reviewed G-protein coupled receptor
O95718 BXGT005392 Steroid hormone receptor ERR2 2103 reviewed Nuclear receptor
O95835 BXGT005400 Serine/threonine-protein kinase LATS1 9113 reviewed Kinase
P00352 BXGT005510 Retinal dehydrogenase 1 216 reviewed Enzyme
P00533 BXGT005575 Epidermal growth factor receptor 1956 reviewed Kinase
P00747 BXGT005639 Plasminogen 5340 reviewed Enzyme
P00749 BXGT005641 Urokinase-type plasminogen activator 5328 reviewed Enzyme
P01106 BXGT005730 Myc proto-oncogene protein 4609 reviewed Transcription factor
P01111 BXGT005731 GTPase NRas 4893 reviewed Enzyme modulator
P01112 BXGT005732 GTPase HRas 3265 reviewed Enzyme modulator
P01116 BXGT005733 GTPase KRas 3845 reviewed Enzyme modulator
P01133 BXGT005736 Pro-epidermal growth factor 1950 reviewed
P01137 BXGT005737 Transforming growth factor beta-1 proprotein 7040 reviewed Signaling
P01375 BXGT005753 Tumor necrosis factor 7124 reviewed Signaling
P02545 BXGT005889 Prelamin-A/C 4000 reviewed
P02741 BXGT005936 C-reactive protein 1401 reviewed
P02751 BXGT005943 Fibronectin 2335 reviewed Signaling
P02768 BXGT005955 Serum albumin 213 reviewed Transporter
P03372 BXGT006059 Estrogen receptor 2099 reviewed Nuclear receptor
P03956 BXGT006120 Interstitial collagenase 4312 reviewed Enzyme
P04049 BXGT006133 RAF proto-oncogene serine/threonine-protein kinase 5894 reviewed Kinase
P04271 BXGT006177 Protein S100-B 6285 reviewed Calcium-binding protein
P04626 BXGT006238 Receptor tyrosine-protein kinase erbB-2 2064 reviewed Kinase
P04629 BXGT006239 High affinity nerve growth factor receptor 4914 reviewed Kinase
P04637 BXGT006243 Cellular tumor antigen p53 7157 reviewed Transcription factor
P05106 BXGT006315 Integrin beta-3 3690 reviewed Receptor
P05121 BXGT006320 Plasminogen activator inhibitor 1 5054 reviewed Enzyme modulator
P05154 BXGT006327 Plasma serine protease inhibitor 5104 reviewed Enzyme modulator
P05231 BXGT006345 Interleukin-6 3569 reviewed
P07204 BXGT006567 Thrombomodulin 7056 reviewed
P07900 BXGT006696 Heat shock protein HSP 90-alpha 3320 reviewed Chaperone
P08069 BXGT006723 Insulin-like growth factor 1 receptor 3480 reviewed Kinase
P08151 BXGT006731 Zinc finger protein GLI1 2735 reviewed
P08183 BXGT006741 ATP-dependent translocase ABCB1 5243 reviewed Transporter
P08575 BXGT006793 Receptor-type tyrosine-protein phosphatase C 5788 reviewed Enzyme
P08581 BXGT006794 Hepatocyte growth factor receptor 4233 reviewed Kinase
P08670 BXGT006810 Vimentin 7431 reviewed
P08758 BXGT006821 Annexin A5 308 reviewed
P08842 BXGT006830 Steryl-sulfatase 412 reviewed Enzyme
P08922 BXGT006843 Proto-oncogene tyrosine-protein kinase ROS 6098 reviewed Kinase
P09874 BXGT006934 Poly [ADP-ribose] polymerase 1 142 reviewed
P10415 BXGT007567 Apoptosis regulator Bcl-2 596 reviewed Signaling
P10721 BXGT007605 Mast/stem cell growth factor receptor Kit 3815 reviewed Kinase
P11362 BXGT007693 Fibroblast growth factor receptor 1 2260 reviewed Kinase
P11388 BXGT007697 DNA topoisomerase 2-alpha 7153 reviewed
P11802 BXGT007750 Cyclin-dependent kinase 4 1019 reviewed Kinase
P12004 BXGT007766 Proliferating cell nuclear antigen 5111 reviewed Nucleic acid binding
P13500 BXGT007916 C-C motif chemokine 2 6347 reviewed Signaling
P13726 BXGT007950 Tissue factor 2152 reviewed Receptor
P14780 BXGT008053 Matrix metalloproteinase-9 4318 reviewed Enzyme
P15144 BXGT008087 Aminopeptidase N 290 reviewed Enzyme
P15151 BXGT008089 Poliovirus receptor 5817 reviewed
P15311 BXGT008106 Ezrin 7430 reviewed Cellular structure
P15531 BXGT008136 Nucleoside diphosphate kinase A 4830 reviewed Kinase
P15692 BXGT008147 Vascular endothelial growth factor A 7422 reviewed Signaling
P16070 BXGT008186 CD44 antigen 960 reviewed
P16109 BXGT008194 P-selectin 6403 reviewed
P16234 BXGT008209 Platelet-derived growth factor receptor alpha 5156 reviewed Kinase
P16455 BXGT008229 Methylated-DNA--protein-cysteine methyltransferase 4255 reviewed
P16581 BXGT008245 E-selectin 6401 reviewed
P18846 BXGT008430 Cyclic AMP-dependent transcription factor ATF-1 466 reviewed
P19544 BXGT008494 Wilms tumor protein 7490 reviewed Nucleic acid binding
P20936 BXGT008619 Ras GTPase-activating protein 1 5921 reviewed Enzyme modulator
P21579 BXGT008665 Synaptotagmin-1 6857 reviewed Transporter
P22455 BXGT008772 Fibroblast growth factor receptor 4 2264 reviewed Kinase
P22894 BXGT008815 Neutrophil collagenase 4317 reviewed Enzyme
P22897 BXGT008816 Macrophage mannose receptor 1 4360 reviewed
P23297 BXGT008848 Protein S100-A1 6271 reviewed Calcium-binding protein
P25311 BXGT009036 Zinc-alpha-2-glycoprotein 563 reviewed
P26447 BXGT009114 Protein S100-A4 6275 reviewed Calcium-binding protein
P30086 BXGT009400 Phosphatidylethanolamine-binding protein 1 5037 reviewed Enzyme modulator
P30874 BXGT009475 Somatostatin receptor type 2 6752 reviewed G-protein coupled receptor
P31749 BXGT009574 RAC-alpha serine/threonine-protein kinase 207 reviewed Kinase
P33527 BXGT009728 Multidrug resistance-associated protein 1 4363 reviewed Transporter
P35222 BXGT009799 Catenin beta-1 1499 reviewed
P35869 BXGT009877 Aryl hydrocarbon receptor 196 reviewed Transcription factor
P35968 BXGT009887 Vascular endothelial growth factor receptor 2 3791 reviewed Kinase
P38398 BXGT010037 Breast cancer type 1 susceptibility protein 672 reviewed Enzyme
P39060 BXGT010088 Collagen alpha-1(XVIII) chain 80781 reviewed
P40692 BXGT010195 DNA mismatch repair protein Mlh1 4292 reviewed Nucleic acid binding
P40763 BXGT010202 Signal transducer and activator of transcription 3 6774 reviewed Nucleic acid binding
P42345 BXGT010304 Serine/threonine-protein kinase mTOR 2475 reviewed Kinase
P42574 BXGT010317 Caspase-3 836 reviewed Enzyme
P43246 BXGT010371 DNA mismatch repair protein Msh2 4436 reviewed Nucleic acid binding
P46937 BXGT010554 Transcriptional coactivator YAP1 10413 reviewed Enzyme modulator
P49767 BXGT010739 Vascular endothelial growth factor C 7424 reviewed Signaling
P49841 BXGT010750 Glycogen synthase kinase-3 beta 2932 reviewed Kinase
P50591 BXGT010814 Tumor necrosis factor ligand superfamily member 10 8743 reviewed Signaling
P51532 BXGT010852 Transcription activator BRG1 6597 reviewed Epigenetic regulator
P54278 BXGT011038 Mismatch repair endonuclease PMS2 5395 reviewed Nucleic acid binding
P54760 BXGT011075 Ephrin type-B receptor 4 2050 reviewed Kinase
P55211 BXGT011111 Caspase-9 842 reviewed Enzyme
P56524 BXGT011176 Histone deacetylase 4 9759 reviewed Epigenetic regulator
P58335 BXGT011233 Anthrax toxin receptor 2 118429 reviewed Receptor
P60484 BXGT011307 Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN 5728 reviewed Enzyme
P60568 BXGT011315 Interleukin-2 3558 reviewed
P78527 BXGT011846 DNA-dependent protein kinase catalytic subunit 5591 reviewed Kinase
P78536 BXGT011847 Disintegrin and metalloproteinase domain-containing protein 17 6868 reviewed
P98170 BXGT012231 E3 ubiquitin-protein ligase XIAP 331 reviewed Enzyme modulator
Q00987 BXGT012559 E3 ubiquitin-protein ligase Mdm2 4193 reviewed Nucleic acid binding
Q01974 BXGT012628 Tyrosine-protein kinase transmembrane receptor ROR2 4920 reviewed Kinase
Q12778 BXGT013263 Forkhead box protein O1 2308 reviewed
Q13126 BXGT013313 S-methyl-5'-thioadenosine phosphorylase 4507 reviewed Enzyme
Q13188 BXGT013324 Serine/threonine-protein kinase 3 6788 reviewed Kinase
Q13257 BXGT013333 Mitotic spindle assembly checkpoint protein MAD2A 4085 reviewed
Q13535 BXGT013370 Serine/threonine-protein kinase ATR 545 reviewed Kinase
Q13822 BXGT013396 Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 5168 reviewed Enzyme
Q14191 BXGT013452 Werner syndrome ATP-dependent helicase 7486 reviewed Enzyme
Q15116 BXGT013539 Programmed cell death protein 1 5133 reviewed
Q15257 BXGT013554 Serine/threonine-protein phosphatase 2A activator 5524 reviewed Enzyme modulator
Q15392 BXGT013566 Delta(24)-sterol reductase 1718 reviewed Enzyme
Q15910 BXGT013612 Histone-lysine N-methyltransferase EZH2 2146 reviewed Epigenetic regulator
Q16665 BXGT013653 Hypoxia-inducible factor 1-alpha 3091 reviewed Transcription factor
Q16790 BXGT013670 Carbonic anhydrase 9 768 reviewed
Q8WWL7 BXGT019000 G2/mitotic-specific cyclin-B3 85417 reviewed Enzyme modulator
Q92731 BXGT019366 Estrogen receptor beta 2100 reviewed Nuclear receptor
Q96EB6 BXGT019646 NAD-dependent protein deacetylase sirtuin-1 23411 reviewed Epigenetic regulator
Q99814 BXGT019965 Endothelial PAS domain-containing protein 1 2034 reviewed Transcription factor
Q99816 BXGT019966 Tumor susceptibility gene 101 protein 7251 reviewed Enzyme
Q9BZS1 BXGT020203 Forkhead box protein P3 50943 reviewed
Q9NRM7 BXGT021190 Serine/threonine-protein kinase LATS2 26524 reviewed Kinase
Q9NZQ7 BXGT021281 Programmed cell death 1 ligand 1 29126 reviewed Receptor
Q9P2K8 BXGT021302 eIF-2-alpha kinase GCN2 440275 reviewed
Q9Y251 BXGT022215 Heparanase 10855 reviewed Enzyme
Q9Y2Q3 BXGT022242 Glutathione S-transferase kappa 1 373156 reviewed
Q9Y6A5 BXGT022325 Transforming acidic coiled-coil-containing protein 3 10460 reviewed
P16284 BXGT022972 Platelet endothelial cell adhesion molecule 5175 reviewed Cell adhesion
Q13635 BXGT024910 Protein patched homolog 1 5727 reviewed
P11836 BXGT025994 B-lymphocyte antigen CD20 931 reviewed Receptor
P19532 BXGT026110 Transcription factor E3 7030 reviewed
The  disease-related  compounds
Compounds
BXGC Id Compound Name Structure Molecular Weight Number of targets?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease
The  disease-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compounds in food?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease