adisease

Showing entry for Abdominal Pain

General Disease Information
BXGD Id	BXGD000005
Disease Name	Abdominal Pain
Disease CUI Id	C0000737
MeSH Codes	C23
Disease Class Name	Pathological Conditions, Signs and Symptoms
Semantic Type	Sign or Symptom
Human Phenotype Ontology Id	HP:0025031 HP:0025142
Human Phenotype Ontology Term	Abnormality of the digestive system; Constitutional symptom
Disease Ontology Id
Disease Ontology Class Name
Disorder Network	disorder-protein-compound-food associations

The disease-related target proteins

Proteins

Uniport Id	BXGT Id	Protein Name	Gene	Status	Protein Class
Uniport Id	BXGT Id	Protein name	Gene	Status	Protein class
A0A024RAV5	BXGT000013	V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog, isoform CRA_b	3845	unreviewed
O00206	BXGT003894	Toll-like receptor 4	7099	reviewed
O00451	BXGT003923	GDNF family receptor alpha-2	2675	reviewed
O00519	BXGT003934	Fatty-acid amide hydrolase 1	2166	reviewed
O00555	BXGT003936	Voltage-dependent P/Q-type calcium channel subunit alpha-1A	773	reviewed	Ion channel
O14841	BXGT004105	5-oxoprolinase	26873	reviewed	Enzyme
O14936	BXGT004114	Peripheral plasma membrane protein CASK	8573	reviewed	Kinase
O15553	BXGT004181	Pyrin	4210	reviewed
O43280	BXGT004582	Trehalase	11181	reviewed
O60674	BXGT004892	Tyrosine-protein kinase JAK2	3717	reviewed	Kinase
O75030	BXGT005096	Microphthalmia-associated transcription factor	4286	reviewed
O75762	BXGT005151	Transient receptor potential cation channel subfamily A member 1	8989	reviewed	Ion channel
O75828	BXGT005154	Carbonyl reductase [NADPH] 3	874	reviewed
O95477	BXGT005383	Phospholipid-transporting ATPase ABCA1	19	reviewed	Transporter
P00734	BXGT005630	Prothrombin	2147	reviewed	Enzyme
P00736	BXGT005632	Complement C1r subcomponent	715	reviewed	Enzyme
P00750	BXGT005642	Tissue-type plasminogen activator	5327	reviewed	Enzyme
P01106	BXGT005730	Myc proto-oncogene protein	4609	reviewed	Transcription factor
P01116	BXGT005733	GTPase KRas	3845	reviewed	Enzyme modulator
P01138	BXGT005738	Beta-nerve growth factor	4803	reviewed	Signaling
P01275	BXGT005747	Glucagon	2641	reviewed
P01375	BXGT005753	Tumor necrosis factor	7124	reviewed	Signaling
P01889	BXGT005809	HLA class I histocompatibility antigen, B-7 alpha chain	3106	reviewed
P01909	BXGT005815	HLA class II histocompatibility antigen, DQ alpha 1 chain	3117	reviewed	Immune response
P01911	BXGT005816	HLA class II histocompatibility antigen, DRB1-15 beta chain	3123	reviewed	Immune response
P01920	BXGT005817	HLA class II histocompatibility antigen, DQ beta 1 chain	3119	reviewed	Immune response
P02549	BXGT005890	Spectrin alpha chain, erythrocytic 1	6708	reviewed
P02730	BXGT005935	Band 3 anion transport protein	6521	reviewed	Transporter
P02741	BXGT005936	C-reactive protein	1401	reviewed
P02750	BXGT005942	Leucine-rich alpha-2-glycoprotein	116844	reviewed
P03372	BXGT006059	Estrogen receptor	2099	reviewed	Nuclear receptor
P03886	BXGT006108	NADH-ubiquinone oxidoreductase chain 1	4535	reviewed	Enzyme
P03905	BXGT006113	NADH-ubiquinone oxidoreductase chain 4	4538	reviewed	Enzyme
P03915	BXGT006114	NADH-ubiquinone oxidoreductase chain 5	4540	reviewed	Enzyme
P03923	BXGT006115	NADH-ubiquinone oxidoreductase chain 6	4541	reviewed
P04062	BXGT006140	Lysosomal acid glucosylceramidase	2629	reviewed
P04150	BXGT006154	Glucocorticoid receptor	2908	reviewed	Nuclear receptor
P04440	BXGT006216	HLA class II histocompatibility antigen, DP beta 1 chain	3115	reviewed	Immune response
P04626	BXGT006238	Receptor tyrosine-protein kinase erbB-2	2064	reviewed	Kinase
P04637	BXGT006243	Cellular tumor antigen p53	7157	reviewed	Transcription factor
P04732	BXGT006252	Metallothionein-1E	4493	reviewed
P05062	BXGT006305	Fructose-bisphosphate aldolase B	229	reviewed
P05155	BXGT006328	Plasma protease C1 inhibitor	710	reviewed	Enzyme modulator
P05156	BXGT006329	Complement factor I	3426	reviewed
P05164	BXGT006333	Myeloperoxidase	4353	reviewed	Enzyme
P05231	BXGT006345	Interleukin-6	3569	reviewed
P06280	BXGT006433	Alpha-galactosidase A	2717	reviewed
P06748	BXGT006497	Nucleophosmin	4869	reviewed	Chaperone
P06858	BXGT006515	Lipoprotein lipase	4023	reviewed	Enzyme
P07477	BXGT006629	Trypsin-1	5644	reviewed	Enzyme
P07478	BXGT006630	Trypsin-2	5645	reviewed	Enzyme
P07949	BXGT006703	Proto-oncogene tyrosine-protein kinase receptor Ret	5979	reviewed	Kinase
P08174	BXGT006739	Complement decay-accelerating factor	1604	reviewed
P08183	BXGT006741	ATP-dependent translocase ABCB1	5243	reviewed	Transporter
P08246	BXGT006756	Neutrophil elastase	1991	reviewed	Enzyme
P08397	BXGT006768	Porphobilinogen deaminase	3145	reviewed	Enzyme
P08581	BXGT006794	Hepatocyte growth factor receptor	4233	reviewed	Kinase
P08603	BXGT006798	Complement factor H	3075	reviewed
P10276	BXGT007553	Retinoic acid receptor alpha	5914	reviewed	Nuclear receptor
P10323	BXGT007557	Acrosin	49	reviewed	Enzyme
P10644	BXGT007597	cAMP-dependent protein kinase type I-alpha regulatory subunit	5573	reviewed
P10721	BXGT007605	Mast/stem cell growth factor receptor Kit	3815	reviewed	Kinase
P11413	BXGT007701	Glucose-6-phosphate 1-dehydrogenase	2539	reviewed	Enzyme
P12643	BXGT007830	Bone morphogenetic protein 2	650	reviewed	Signaling
P13569	BXGT007923	Cystic fibrosis transmembrane conductance regulator	1080	reviewed	Ion channel
P13637	BXGT007933	Sodium/potassium-transporting ATPase subunit alpha-3	478	reviewed	Transporter
P13716	BXGT007948	Delta-aminolevulinic acid dehydratase	210	reviewed	Enzyme
P14174	BXGT007991	Macrophage migration inhibitory factor	4282	reviewed
P15085	BXGT008077	Carboxypeptidase A1	1357	reviewed	Enzyme
P15529	BXGT008134	Membrane cofactor protein	4179	reviewed
P15884	BXGT008166	Transcription factor 4	6925	reviewed	Transcription factor
P16157	BXGT008203	Ankyrin-1	286	reviewed
P16410	BXGT008224	Cytotoxic T-lymphocyte protein 4	1493	reviewed
P17948	BXGT008358	Vascular endothelial growth factor receptor 1	2321	reviewed	Kinase
P19224	BXGT008468	UDP-glucuronosyltransferase 1-6	54578	reviewed
P19438	BXGT008480	Tumor necrosis factor receptor superfamily member 1A	7132	reviewed
P19544	BXGT008494	Wilms tumor protein	7490	reviewed	Nucleic acid binding
P19971	BXGT008537	Thymidine phosphorylase	1890	reviewed	Enzyme
P22033	BXGT008721	Methylmalonyl-CoA mutase, mitochondrial	4594	reviewed	Enzyme
P22309	BXGT008753	UDP-glucuronosyltransferase 1-1	54658	reviewed
P23560	BXGT008883	Brain-derived neurotrophic factor	627	reviewed	Signaling
P23945	BXGT008931	Follicle-stimulating hormone receptor	2492	reviewed	G-protein coupled receptor
P24158	BXGT008951	Myeloblastin	5657	reviewed	Enzyme
P24298	BXGT008960	Alanine aminotransferase 1	2875	reviewed	Enzyme
P24530	BXGT008975	Endothelin receptor type B	1910	reviewed	G-protein coupled receptor
P27487	BXGT009187	Dipeptidyl peptidase 4	1803	reviewed	Enzyme
P30536	BXGT009435	Translocator protein	706	reviewed
P31639	BXGT009556	Sodium/glucose cotransporter 2	6524	reviewed	Transporter
P31645	BXGT009558	Sodium-dependent serotonin transporter	6532	reviewed	Transporter
P31947	BXGT009589	14-3-3 protein sigma	2810	reviewed	Chaperone
P35222	BXGT009799	Catenin beta-1	1499	reviewed
P35354	BXGT009816	Prostaglandin G/H synthase 2	5743	reviewed	Enzyme
P35372	BXGT009823	Mu-type opioid receptor	4988	reviewed	G-protein coupled receptor
P36551	BXGT009927	Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial	1371	reviewed	Enzyme
P36894	BXGT009939	Bone morphogenetic protein receptor type-1A	657	reviewed	Kinase
P37173	BXGT009970	TGF-beta receptor type-2	7048	reviewed	Kinase
P38398	BXGT010037	Breast cancer type 1 susceptibility protein	672	reviewed	Enzyme
P40692	BXGT010195	DNA mismatch repair protein Mlh1	4292	reviewed	Nucleic acid binding
P40763	BXGT010202	Signal transducer and activator of transcription 3	6774	reviewed	Nucleic acid binding
P41180	BXGT010230	Extracellular calcium-sensing receptor	846	reviewed	G-protein coupled receptor
P41231	BXGT010240	P2Y purinoceptor 2	5029	reviewed	G-protein coupled receptor
P42336	BXGT010302	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	5290	reviewed	Kinase
P43220	BXGT010367	Glucagon-like peptide 1 receptor	2740	reviewed	G-protein coupled receptor
P43246	BXGT010371	DNA mismatch repair protein Msh2	4436	reviewed	Nucleic acid binding
P47871	BXGT010592	Glucagon receptor	2642	reviewed	G-protein coupled receptor
P47900	BXGT010595	P2Y purinoceptor 1	5028	reviewed	G-protein coupled receptor
P50336	BXGT010791	Protoporphyrinogen oxidase	5498	reviewed
P51617	BXGT010868	Interleukin-1 receptor-associated kinase 1	3654	reviewed	Kinase
P51692	BXGT010885	Signal transducer and activator of transcription 5B	6777	reviewed	Nucleic acid binding
P52701	BXGT010943	DNA mismatch repair protein Msh6	2956	reviewed	Nucleic acid binding
P52952	BXGT010966	Homeobox protein Nkx-2.5	1482	reviewed	Transcription factor
P53667	BXGT011008	LIM domain kinase 1	3984	reviewed	Kinase
P54098	BXGT011030	DNA polymerase subunit gamma-1	5428	reviewed	Enzyme
P54278	BXGT011038	Mismatch repair endonuclease PMS2	5395	reviewed	Nucleic acid binding
P54707	BXGT011068	Potassium-transporting ATPase alpha chain 2	479	reviewed	Transporter
P55085	BXGT011104	Proteinase-activated receptor 2	2150	reviewed	G-protein coupled receptor
P55265	BXGT011117	Double-stranded RNA-specific adenosine deaminase	103	reviewed	Enzyme
P57059	BXGT011210	Serine/threonine-protein kinase SIK1	150094	reviewed
P60484	BXGT011307	Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN	5728	reviewed	Enzyme
P61011	BXGT011346	Signal recognition particle 54 kDa protein	6729	reviewed	Nucleic acid binding
P61073	BXGT011352	C-X-C chemokine receptor type 4	7852	reviewed	G-protein coupled receptor
P68871	BXGT011615	Hemoglobin subunit beta	3043	reviewed
P78358	BXGT011838	Cancer/testis antigen 1	246100	reviewed
P80511	BXGT011914	Protein S100-A12	6283	reviewed	Calcium-binding protein
Q05516	BXGT012822	Zinc finger and BTB domain-containing protein 16	7704	reviewed	Transcription factor
Q13485	BXGT013363	Mothers against decapentaplegic homolog 4	4089	reviewed	Transcription factor
Q13489	BXGT013364	Baculoviral IAP repeat-containing protein 3	330	reviewed	Enzyme modulator
Q14108	BXGT013440	Lysosome membrane protein 2	950	reviewed	Receptor
Q14524	BXGT013478	Sodium channel protein type 5 subunit alpha	6331	reviewed	Ion channel
Q15831	BXGT013604	Serine/threonine-protein kinase STK11	6794	reviewed	Kinase
Q30201	BXGT014297	Hereditary hemochromatosis protein	3077	reviewed
Q5VWK5	BXGT015891	Interleukin-23 receptor	149233	reviewed	Signaling
Q5Y7D3	BXGT015912	HLA class II histocompatibility antigen DQ beta chain	3119	unreviewed
Q6N021	BXGT016378	Methylcytosine dioxygenase TET2	54790	reviewed
Q7L266	BXGT016993	Isoaspartyl peptidase/L-asparaginase	80150	reviewed	Enzyme
Q7LG56	BXGT016999	Ribonucleoside-diphosphate reductase subunit M2 B	50484	reviewed	Enzyme
Q86YC2	BXGT017633	Partner and localizer of BRCA2	79728	reviewed
Q8NER1	BXGT018556	Transient receptor potential cation channel subfamily V member 1	7442	reviewed	Ion channel
Q8TD43	BXGT018806	Transient receptor potential cation channel subfamily M member 4	54795	reviewed	Ion channel
Q92887	BXGT019389	Canalicular multispecific organic anion transporter 1	1244	reviewed	Transporter
Q96P20	BXGT019704	NACHT, LRR and PYD domains-containing protein 3	114548	reviewed
Q99700	BXGT019949	Ataxin-2	6311	reviewed	Nucleic acid binding
Q99895	BXGT019974	Chymotrypsin-C	11330	reviewed
Q9H251	BXGT020449	Cadherin-23	64072	reviewed
Q9HAW7	BXGT020508	UDP-glucuronosyltransferase 1-7	54577	reviewed
Q9HC29	BXGT020526	Nucleotide-binding oligomerization domain-containing protein 2	64127	reviewed	Enzyme
Q9HC97	BXGT020527	G-protein coupled receptor 35	2859	reviewed	G-protein coupled receptor
Q9NP99	BXGT021148	Triggering receptor expressed on myeloid cells 1	54210	reviewed
Q9NPD5	BXGT021151	Solute carrier organic anion transporter family member 1B3	28234	reviewed	Transporter
Q9NZ08	BXGT021266	Endoplasmic reticulum aminopeptidase 1	51752	reviewed	Enzyme
Q9UDY8	BXGT021670	Mucosa-associated lymphoid tissue lymphoma translocation protein 1	10892	reviewed	Enzyme
Q9UKU7	BXGT021749	Isobutyryl-CoA dehydrogenase, mitochondrial	27034	reviewed	Enzyme
Q9Y2M0	BXGT022241	Fanconi-associated nuclease 1	22909	reviewed
Q9Y2R2	BXGT022243	Tyrosine-protein phosphatase non-receptor type 22	26191	reviewed
Q9Y6L6	BXGT022334	Solute carrier organic anion transporter family member 1B1	10599	reviewed	Transporter
Q92847	BXGT022673	Growth hormone secretagogue receptor type 1	2693	reviewed	G-protein coupled receptor
P20036	BXGT022764	HLA class II histocompatibility antigen, DP alpha 1 chain	3113	reviewed	Immune response
P26045	BXGT022810	Tyrosine-protein phosphatase non-receptor type 3	5774	reviewed
P19235	BXGT022895	Erythropoietin receptor	2057	reviewed	Receptor
P25054	BXGT022961	Adenomatous polyposis coli protein	324	reviewed
Q99748	BXGT023217	Neurturin	4902	reviewed	Signaling
Q8IYW5	BXGT023493	E3 ubiquitin-protein ligase RNF168	165918	reviewed
P00395	BXGT023596	Cytochrome c oxidase subunit 1	4512	reviewed	Enzyme
P29590	BXGT024350	Protein PML	5371	reviewed
P51608	BXGT025073	Methyl-CpG-binding protein 2	4204	reviewed	Epigenetic regulator
Q14980	BXGT025336	Nuclear mitotic apparatus protein 1	4926	reviewed
P35250	BXGT025854	Replication factor C subunit 2	5982	reviewed	Enzyme
Q14566	BXGT025969	DNA replication licensing factor MCM6	4175	reviewed	Enzyme
P00403	BXGT026137	Cytochrome c oxidase subunit 2	4513	reviewed	Enzyme

The disease-related compounds

Compounds

BXGC Id	Compound Name	Structure	Molecular Weight	Number of targets^{?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease}

The disease-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compounds in food^{?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease}