Showing entry for Phenol


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Compound Information
BXGC IdBXGC0000536
Compound NamePhenol
Structure
FormulaC6H6O
InchiKeyISWSIDIOOBJBQZ-UHFFFAOYSA-N
SMILESOC1=CC=CC=C1
InchiInChI=1S/C6H6O/c7-6-4-2-1-3-5-6/h1-5,7H
IUPACphenol
Molecular Weight94.11
Pubchem Id996
Chembl IdCHEMBL14060
Targets of Information Source
DrugBank DB03255
Uniport Id BXGT Id Protein Name Status Protein Class Gene Groups Target Type
Uniport Id BXGT Id Protein Name Status Protein Class Gene Groups Target Type
P00800 BXGT005661 Thermolysin reviewed - npr approved; experimental -
P02768 BXGT005955 Serum albumin reviewed Transporter ALB approved; experimental -
PDB IPH
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM Ka M-1
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM Ka M-1
P01308 BXGT005749 Insulin reviewed INS - - - - -
P06875 BXGT006520 Penicillin G acylase reviewed pac - 82000 - - -
P00800 BXGT005661 Thermolysin reviewed npr - - - - -
P15245 BXGT008099 Phenol hydroxylase reviewed - - - - -
Q05603 BXGT012829 Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase reviewed cobT - - - - -
P00720 BXGT005625 Endolysin reviewed E - - - 91000 -
P01315 BXGT005750 Insulin reviewed INS - - - - -
Q41290 BXGT014570 Dhurrinase unreviewed - - - - -
P22869 BXGT008811 Methane monooxygenase component A alpha chain reviewed mmoX - - - - -
P00431 BXGT005533 Cytochrome c peroxidase, mitochondrial reviewed CCP1 - - - 4100000 -
P00760 BXGT005644 Cationic trypsin reviewed - - - - -
P07445 BXGT006626 Steroid Delta-isomerase reviewed ksi - - - 135000 -
P02791 BXGT005965 Ferritin light chain reviewed FTL - - - 16500000 -
P00720 BXGT005625 Endolysin reviewed E - - - - 9150
Q8X5Q7 BXGT019039 Uncharacterized protein unreviewed ECs_5070 - - - - -
O95149 BXGT005350 Snurportin-1 reviewed SNUPN - - - - -
P17612 BXGT008322 cAMP-dependent protein kinase catalytic subunit alpha reviewed PRKACA Kinase - - - -
Q00456 BXGT012520 Toluene-4-monooxygenase system, hydroxylase component subunit alpha reviewed tmoA - - - - -
Q00460 BXGT012524 Toluene-4-monooxygenase system, hydroxylase component subunit beta reviewed tmoE - - - - -
P02185 BXGT005855 Myoglobin reviewed MB - - - - -
P00431 BXGT005533 Cytochrome c peroxidase, mitochondrial reviewed CCP1 - - - - -
Q9UKV8 BXGT021752 Protein argonaute-2 reviewed AGO2 - - - - -
F6MZ55 BXGT003298 Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase unreviewed arsA - - - - -
P00720 BXGT005625 Endolysin reviewed E - - - 103000 -
B3LRE1 BXGT002056 Peroxidase unreviewed SCRG_04081 - - - - -
O84957 BXGT005231 Positive phenol-degradative gene regulator unreviewed poxR - - - - -
Q9VV42 BXGT021905 HL08057p unreviewed Pdh - - - - -
Q43965 BXGT014598 Phenol regulator MopR reviewed mopR - - - 460 -
Q96TR6 BXGT019748 Laccase unreviewed lcc1 - - - - -
Q9NRF2 BXGT021185 SH2B adapter protein 1 reviewed SH2B1 - - - - -
Q7WSM9 BXGT024398 Positive regulator CapR unreviewed - - - - -
P28482 BXGT009263 Mitogen-activated protein kinase 1 reviewed MAPK1 Kinase - - - -
Binding DB 26187
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM EC50 nM
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM EC50 nM
reviewed BXGT005689 Carbonic anhydrase 1 reviewed CA1 10200 - - -
reviewed BXGT005690 Carbonic anhydrase 2 reviewed CA2 5500 - - -
reviewed BXGT006627 Carbonic anhydrase 3 reviewed CA3 2700 - - -
reviewed BXGT008802 Carbonic anhydrase 4 reviewed CA4 9500 - - -
reviewed BXGT009796 Carbonic anhydrase 5A, mitochondrial reviewed CA5A 218000 - - -
reviewed BXGT022229 Carbonic anhydrase 5B, mitochondrial reviewed CA5B 543000 - - -
reviewed BXGT008844 Carbonic anhydrase 6 reviewed CA6 208000 - - -
reviewed BXGT010364 Carbonic anhydrase 7 reviewed CA7 710000 - - -
reviewed BXGT013670 Carbonic anhydrase 9 reviewed CA9 8800 - - -
reviewed BXGT004601 Carbonic anhydrase 12 reviewed CA12 9200 - - -
reviewed BXGT020260 Carbonic anhydrase 13 reviewed Ca13 697000 - - -
reviewed BXGT021769 Carbonic anhydrase 14 reviewed CA14 11500 - - -
reviewed BXGT014517 Carbonic anhydrase 3 reviewed CA3 - 4630 - -
reviewed BXGT005689 Carbonic anhydrase 1 reviewed CA1 10240 - - -
reviewed BXGT005690 Carbonic anhydrase 2 reviewed CA2 5600 - - -
reviewed BXGT008802 Carbonic anhydrase 4 reviewed CA4 9700 - - -
reviewed BXGT008844 Carbonic anhydrase 6 reviewed CA6 210000 - - -
reviewed BXGT005689 Carbonic anhydrase 1 reviewed CA1 17300 - - -
reviewed BXGT005690 Carbonic anhydrase 2 reviewed CA2 7400 - - -
reviewed BXGT014517 Carbonic anhydrase 3 reviewed CA3 4600 - - -
reviewed BXGT008802 Carbonic anhydrase 4 reviewed CA4 14300 - - -
reviewed BXGT014517 Carbonic anhydrase 3 reviewed CA3 4630 - - -
reviewed BXGT006059 Estrogen receptor reviewed Nuclear receptor ESR1 - >250000 - -
reviewed BXGT019366 Estrogen receptor beta reviewed Nuclear receptor ESR2 - >250000 - -
reviewed BXGT022229 Carbonic anhydrase 5B, mitochondrial reviewed CA5B >500000 - - -
reviewed BXGT010364 Carbonic anhydrase 7 reviewed CA7 >500000 - - -
reviewed BXGT020260 Carbonic anhydrase 13 reviewed Ca13 >500000 - - -
reviewed BXGT019994 Carbonic anhydrase 15 reviewed Ca15 10500 - - -
reviewed BXGT005689 Carbonic anhydrase 1 reviewed CA1 10100 - - -
reviewed BXGT015288 Carbonic anhydrase reviewed NCE103 17300 - - -
reviewed BXGT012457 Beta-carbonic anhydrase 1 reviewed mtcA1 64000 - - -
reviewed BXGT018499 Carbonic anhydrase 13 reviewed CA13 697000 - - -
reviewed BXGT008061 Gamma-aminobutyric acid receptor subunit alpha-1 reviewed Ion channel GABRA1 - - - 1000000
reviewed BXGT008061 Gamma-aminobutyric acid receptor subunit alpha-1 reviewed Ion channel GABRA1 - - - 100000000
CHEMBL CHEMBL14060
Uniport Id BXGT Id Protein Name Status Protein Class Gene width="10%">Type Relation value Units
Uniport Id BXGT Id Protein Name Status Protein Class Gene Type Relation value Units
P0A0J7 BXGT006970 Quinolone resistance protein NorA reviewed - norA Activity '>' 128 ug ml-1
P35372 BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 Ki - - -
P37231 BXGT009972 Peroxisome proliferator-activated receptor gamma reviewed Nuclear receptor PPARG Potency - 1122018 nM
O43570 BXGT004601 Carbonic anhydrase 12 reviewed - CA12 Ki '=' 9200 nM
Q16790 BXGT013670 Carbonic anhydrase 9 reviewed - CA9 Ki '=' 8800 nM
P41595 BXGT010267 5-hydroxytryptamine receptor 2B reviewed G-protein coupled receptor HTR2B Ki - - -
P25025 BXGT009006 C-X-C chemokine receptor type 2 reviewed G-protein coupled receptor CXCR2 IC50 - - -
P32238 BXGT009611 Cholecystokinin receptor type A reviewed G-protein coupled receptor CCKAR Ki - - -
P25100 BXGT009017 Alpha-1D adrenergic receptor reviewed G-protein coupled receptor ADRA1D Ki - - -
P30411 BXGT009424 B2 bradykinin receptor reviewed G-protein coupled receptor BDKRB2 IC50 - - -
P41597 BXGT010268 C-C chemokine receptor type 2 reviewed - CCR2 IC50 - - -
P41597 BXGT010268 C-C chemokine receptor type 2 reviewed - CCR2 Ki - - -
P25024 BXGT009005 C-X-C chemokine receptor type 1 reviewed G-protein coupled receptor CXCR1 IC50 - - -
P14416 BXGT008011 D(2) dopamine receptor reviewed G-protein coupled receptor DRD2 IC50 - - -
P35462 BXGT009835 D(3) dopamine receptor reviewed G-protein coupled receptor DRD3 IC50 - - -
P35462 BXGT009835 D(3) dopamine receptor reviewed G-protein coupled receptor DRD3 Ki - - -
P21917 BXGT008707 D(4) dopamine receptor reviewed G-protein coupled receptor DRD4 IC50 - - -
Q01959 BXGT012624 Sodium-dependent dopamine transporter reviewed Transporter SLC6A3 IC50 - - -
Q01959 BXGT012624 Sodium-dependent dopamine transporter reviewed Transporter SLC6A3 Ki - - -
Q92731 BXGT019366 Estrogen receptor beta reviewed Nuclear receptor ESR2 IC50 - - -
P25929 BXGT009078 Neuropeptide Y receptor type 1 reviewed G-protein coupled receptor NPY1R IC50 - - -
P00918 BXGT005690 Carbonic anhydrase 2 reviewed - CA2 Ki '=' 5500 nM
A6XA80 BXGT001522 Leukotriene C4 synthase reviewed - LTC4S Ki - - -
Q9Y271 BXGT022222 Cysteinyl leukotriene receptor 1 reviewed G-protein coupled receptor CYSLTR1 IC50 - - -
P21397 BXGT008644 Amine oxidase [flavin-containing] A reviewed - MAOA Ki - - -
P41143 BXGT010223 Delta-type opioid receptor reviewed G-protein coupled receptor OPRD1 IC50 - - -
P25105 BXGT009021 Platelet-activating factor receptor reviewed G-protein coupled receptor PTAFR IC50 - - -
P08311 BXGT006762 Cathepsin G reviewed Enzyme CTSG IC50 - - -
P04626 BXGT006238 Receptor tyrosine-protein kinase erbB-2 reviewed Kinase ERBB2 Ki - - -
P50406 BXGT010796 5-hydroxytryptamine receptor 6 reviewed G-protein coupled receptor HTR6 IC50 - - -
P25103 BXGT009020 Substance-P receptor reviewed G-protein coupled receptor TACR1 IC50 - - -
P17948 BXGT008358 Vascular endothelial growth factor receptor 1 reviewed Kinase FLT1 IC50 - - -
P18825 BXGT008426 Alpha-2C adrenergic receptor reviewed G-protein coupled receptor ADRA2C Ki - - -
Q9D6N1 BXGT020260 Carbonic anhydrase 13 reviewed - Ca13 Ki '>' 500000 nM
Q12809 BXGT013267 Potassium voltage-gated channel subfamily H member 2 reviewed Ion channel KCNH2 IC50 - - -
P12822 BXGT007850 Angiotensin-converting enzyme reviewed - ACE IC50 - - -
P18507 BXGT008411 Gamma-aminobutyric acid receptor subunit gamma-2 reviewed Ion channel GABRG2 EC50 '=' 100000000 nM
P47870 BXGT010591 Gamma-aminobutyric acid receptor subunit beta-2 reviewed Ion channel GABRB2 EC50 '=' 100000000 nM
P14867 BXGT008061 Gamma-aminobutyric acid receptor subunit alpha-1 reviewed Ion channel GABRA1 EC50 '=' 100000000 nM
P33032 BXGT009689 Melanocortin receptor 5 reviewed G-protein coupled receptor MC5R IC50 - - -
O76074 BXGT005174 cGMP-specific 3',5'-cyclic phosphodiesterase reviewed - PDE5A Ki - - -
P22748 BXGT008802 Carbonic anhydrase 4 reviewed - CA4 Ki '=' 9500 nM
P25100 BXGT009017 Alpha-1D adrenergic receptor reviewed G-protein coupled receptor ADRA1D IC50 - - -
Q99N23 BXGT019994 Carbonic anhydrase 15 reviewed - Ca15 Ki '=' 10500 nM
P25101 BXGT009018 Endothelin-1 receptor reviewed G-protein coupled receptor EDNRA Ki - - -
P35354 BXGT009816 Prostaglandin G/H synthase 2 reviewed Enzyme PTGS2 Ki - - -
P10635 BXGT007595 Cytochrome P450 2D6 reviewed - CYP2D6 IC50 - - -
P08684 BXGT006812 Cytochrome P450 3A4 reviewed Enzyme CYP3A4 IC50 - - -
P00915 BXGT005689 Carbonic anhydrase 1 reviewed - CA1 Ki '=' 10200 nM
P06280 BXGT006433 Alpha-galactosidase A reviewed - GLA Potency '=' 10000 nM
P14780 BXGT008053 Matrix metalloproteinase-9 reviewed Enzyme MMP9 IC50 - - -
P9WPJ7 BXGT012457 Beta-carbonic anhydrase 1 reviewed - mtcA1 Ki '=' 64000 nM
P35218 BXGT009796 Carbonic anhydrase 5A, mitochondrial reviewed - CA5A Ki '=' 218000 nM
P10275 BXGT007552 Androgen receptor reviewed Nuclear receptor AR Potency - 50118 nM
P05181 BXGT006337 Cytochrome P450 2E1 reviewed - CYP2E1 Ki - - -
P31645 BXGT009558 Sodium-dependent serotonin transporter reviewed Transporter SLC6A4 Ki - - -
P04066 BXGT006142 Tissue alpha-L-fucosidase reviewed - FUCA1 Kis '=' 0 mM
Q9ULX7 BXGT021769 Carbonic anhydrase 14 reviewed - CA14 Ki '=' 11500 nM
P25024 BXGT009005 C-X-C chemokine receptor type 1 reviewed G-protein coupled receptor CXCR1 Ki - - -
P35354 BXGT009816 Prostaglandin G/H synthase 2 reviewed Enzyme PTGS2 IC50 - - -
P35367 BXGT009821 Histamine H1 receptor reviewed G-protein coupled receptor HRH1 Ki - - -
O70528 BXGT005068 5-hydroxytryptamine receptor 4 reviewed - HTR4 Ki - - -
P32241 BXGT009613 Vasoactive intestinal polypeptide receptor 1 reviewed G-protein coupled receptor VIPR1 IC50 - - -
Q690N0 BXGT016199 Progesterone receptor unreviewed - PGR IC50 - - -
P24557 BXGT008976 Thromboxane-A synthase reviewed - TBXAS1 IC50 - - -
P18089 BXGT008379 Alpha-2B adrenergic receptor reviewed G-protein coupled receptor ADRA2B IC50 - - -
P18089 BXGT008379 Alpha-2B adrenergic receptor reviewed G-protein coupled receptor ADRA2B Ki - - -
P07451 BXGT006627 Carbonic anhydrase 3 reviewed - CA3 Ki '=' 2700 nM
P13945 BXGT007972 Beta-3 adrenergic receptor reviewed G-protein coupled receptor ADRB3 Ki - - -
P28223 BXGT009239 5-hydroxytryptamine receptor 2A reviewed G-protein coupled receptor HTR2A IC50 - - -
P25103 BXGT009020 Substance-P receptor reviewed G-protein coupled receptor TACR1 Ki - - -
P06239 BXGT006427 Tyrosine-protein kinase Lck reviewed Kinase LCK Ki - - -
O70528 BXGT005068 5-hydroxytryptamine receptor 4 reviewed - HTR4 IC50 - - -
P00533 BXGT005575 Epidermal growth factor receptor reviewed Kinase EGFR Ki - - -
P43140 BXGT010360 Alpha-1A adrenergic receptor reviewed - Adra1a IC50 - - -
P30542 BXGT009436 Adenosine receptor A1 reviewed G-protein coupled receptor ADORA1 Ki - - -
P15823 BXGT008160 Alpha-1B adrenergic receptor reviewed - Adra1b IC50 - - -
P11229 BXGT007676 Muscarinic acetylcholine receptor M1 reviewed G-protein coupled receptor CHRM1 IC50 - - -
P11229 BXGT007676 Muscarinic acetylcholine receptor M1 reviewed G-protein coupled receptor CHRM1 Ki - - -
P41145 BXGT010225 Kappa-type opioid receptor reviewed G-protein coupled receptor OPRK1 IC50 - - -
P41145 BXGT010225 Kappa-type opioid receptor reviewed G-protein coupled receptor OPRK1 Ki - - -
P25105 BXGT009021 Platelet-activating factor receptor reviewed G-protein coupled receptor PTAFR Ki - - -
P25021 BXGT009004 Histamine H2 receptor reviewed G-protein coupled receptor HRH2 IC50 - - -
P28482 BXGT009263 Mitogen-activated protein kinase 1 reviewed Kinase MAPK1 IC50 - - -
P50406 BXGT010796 5-hydroxytryptamine receptor 6 reviewed G-protein coupled receptor HTR6 Ki - - -
P43166 BXGT010364 Carbonic anhydrase 7 reviewed - CA7 Ki '=' 710000 nM
P29466 BXGT009349 Caspase-1 reviewed Enzyme CASP1 IC50 - - -
P06239 BXGT006427 Tyrosine-protein kinase Lck reviewed Kinase LCK IC50 - - -
P28223 BXGT009239 5-hydroxytryptamine receptor 2A reviewed G-protein coupled receptor HTR2A Ki - - -
P23280 BXGT008844 Carbonic anhydrase 6 reviewed - CA6 Ki '=' 208000 nM
P17988 BXGT008363 Sulfotransferase 1A1 reviewed - Sult1a1 Km '=' 19000 nM
Q99720 BXGT019955 Sigma non-opioid intracellular receptor 1 reviewed - SIGMAR1 Ki - - -
P19327 BXGT008472 5-hydroxytryptamine receptor 1A reviewed - Htr1a IC50 - - -
Q8N1Q1 BXGT018499 Carbonic anhydrase 13 reviewed - CA13 Ki '=' 697000 nM
P23975 BXGT008935 Sodium-dependent noradrenaline transporter reviewed Transporter SLC6A2 Ki - - -
P15207 BXGT008096 Androgen receptor reviewed - Ar Ki - - -
P37288 BXGT009977 Vasopressin V1a receptor reviewed G-protein coupled receptor AVPR1A Ki - - -
P51679 BXGT010877 C-C chemokine receptor type 4 reviewed G-protein coupled receptor CCR4 IC50 - - -
P23219 BXGT008837 Prostaglandin G/H synthase 1 reviewed Enzyme PTGS1 IC50 - - -
P11509 BXGT007716 Cytochrome P450 2A6 reviewed - CYP2A6 Ki - - -
Q92731 BXGT019366 Estrogen receptor beta reviewed Nuclear receptor ESR2 Ki - - -
P29274 BXGT009327 Adenosine receptor A2a reviewed G-protein coupled receptor ADORA2A Ki - - -
O42713 BXGT004563 Polyphenol oxidase 2 reviewed - PPO2 Kcat '=' 12 /s
P06241 BXGT006429 Tyrosine-protein kinase Fyn reviewed Kinase FYN IC50 - - -
P19327 BXGT008472 5-hydroxytryptamine receptor 1A reviewed - Htr1a Ki - - -
P08246 BXGT006756 Neutrophil elastase reviewed Enzyme ELANE IC50 - - -
P28482 BXGT009263 Mitogen-activated protein kinase 1 reviewed Kinase MAPK1 Ki - - -
Q08209 BXGT012968 Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform reviewed - PPP3CA Ki - - -
Q9Y2D0 BXGT022229 Carbonic anhydrase 5B, mitochondrial reviewed - CA5B Ki '=' 543000 nM
P18507 BXGT008411 Gamma-aminobutyric acid receptor subunit gamma-2 reviewed Ion channel GABRG2 EC50 '=' 1000000 nM
P47870 BXGT010591 Gamma-aminobutyric acid receptor subunit beta-2 reviewed Ion channel GABRB2 EC50 '=' 1000000 nM
P14867 BXGT008061 Gamma-aminobutyric acid receptor subunit alpha-1 reviewed Ion channel GABRA1 EC50 '=' 1000000 nM
P02769 BXGT005956 Serum albumin reviewed - ALB Log 1/C '=' 3 -
P07943 BXGT006700 Aldo-keto reductase family 1 member B1 reviewed - Akr1b1 IC50 - - -
P29274 BXGT009327 Adenosine receptor A2a reviewed G-protein coupled receptor ADORA2A IC50 - - -
P08588 BXGT006795 Beta-1 adrenergic receptor reviewed G-protein coupled receptor ADRB1 Ki - - -
P0DMS8 BXGT007506 Adenosine receptor A3 reviewed G-protein coupled receptor ADORA3 Ki - - -
Q9Y271 BXGT022222 Cysteinyl leukotriene receptor 1 reviewed G-protein coupled receptor CYSLTR1 Ki - - -
Q5AJ71 BXGT015288 Carbonic anhydrase reviewed - NCE103 Ki '=' 17300 nM
P23219 BXGT008837 Prostaglandin G/H synthase 1 reviewed Enzyme PTGS1 Ki - - -
P11509 BXGT007716 Cytochrome P450 2A6 reviewed - CYP2A6 IC50 - - -
P11712 BXGT007738 Cytochrome P450 2C9 reviewed - CYP2C9 IC50 - - -
P29476 BXGT009354 Nitric oxide synthase, brain reviewed - Nos1 Ki - - -
P12822 BXGT007850 Angiotensin-converting enzyme reviewed - ACE Ki - - -
P30542 BXGT009436 Adenosine receptor A1 reviewed G-protein coupled receptor ADORA1 IC50 - - -
P50052 BXGT010768 Type-2 angiotensin II receptor reviewed G-protein coupled receptor AGTR2 Ki - - -
P30411 BXGT009424 B2 bradykinin receptor reviewed G-protein coupled receptor BDKRB2 Ki - - -
P11712 BXGT007738 Cytochrome P450 2C9 reviewed - CYP2C9 Ki - - -
P05181 BXGT006337 Cytochrome P450 2E1 reviewed - CYP2E1 IC50 - - -
P08684 BXGT006812 Cytochrome P450 3A4 reviewed Enzyme CYP3A4 Ki - - -
P10635 BXGT007595 Cytochrome P450 2D6 reviewed - CYP2D6 Ki - - -
P21917 BXGT008707 D(4) dopamine receptor reviewed G-protein coupled receptor DRD4 Ki - - -
P03372 BXGT006059 Estrogen receptor reviewed Nuclear receptor ESR1 IC50 - - -
P08172 BXGT006737 Muscarinic acetylcholine receptor M2 reviewed G-protein coupled receptor CHRM2 Ki - - -
P08173 BXGT006738 Muscarinic acetylcholine receptor M4 reviewed G-protein coupled receptor CHRM4 IC50 - - -
P23975 BXGT008935 Sodium-dependent noradrenaline transporter reviewed Transporter SLC6A2 IC50 - - -
P21554 BXGT008662 Cannabinoid receptor 1 reviewed G-protein coupled receptor CNR1 IC50 - - -
P12530 BXGT007827 Arachidonate 15-lipoxygenase reviewed - ALOX15 Ki - - -
P08172 BXGT006737 Muscarinic acetylcholine receptor M2 reviewed G-protein coupled receptor CHRM2 IC50 - - -
P29476 BXGT009354 Nitric oxide synthase, brain reviewed - Nos1 IC50 - - -
P35372 BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 IC50 - - -
O76074 BXGT005174 cGMP-specific 3',5'-cyclic phosphodiesterase reviewed - PDE5A IC50 - - -
P51681 BXGT010878 C-C chemokine receptor type 5 reviewed G-protein coupled receptor CCR5 IC50 - - -
P05177 BXGT006336 Cytochrome P450 1A2 reviewed Enzyme CYP1A2 IC50 - - -
P21728 BXGT008686 D(1A) dopamine receptor reviewed G-protein coupled receptor DRD1 Ki - - -
P14416 BXGT008011 D(2) dopamine receptor reviewed G-protein coupled receptor DRD2 Ki - - -
P20781 BXGT008598 Glycine receptor subunit beta reviewed - Glrb Ki - - -
P07727 BXGT006662 Glycine receptor subunit alpha-1 reviewed - Glra1 Ki - - -
P24524 BXGT008974 Glycine receptor subunit alpha-3 reviewed - Glra3 Ki - - -
P22771 BXGT008806 Glycine receptor subunit alpha-2 reviewed - Glra2 Ki - - -
P21554 BXGT008662 Cannabinoid receptor 1 reviewed G-protein coupled receptor CNR1 Ki - - -
P21452 BXGT008653 Substance-K receptor reviewed G-protein coupled receptor TACR2 IC50 - - -
P25101 BXGT009018 Endothelin-1 receptor reviewed G-protein coupled receptor EDNRA IC50 - - -
P03372 BXGT006059 Estrogen receptor reviewed Nuclear receptor ESR1 Ki - - -
P20781 BXGT008598 Glycine receptor subunit beta reviewed - Glrb IC50 - - -
P07727 BXGT006662 Glycine receptor subunit alpha-1 reviewed - Glra1 IC50 - - -
P24524 BXGT008974 Glycine receptor subunit alpha-3 reviewed - Glra3 IC50 - - -
P22771 BXGT008806 Glycine receptor subunit alpha-2 reviewed - Glra2 IC50 - - -
P04035 BXGT006129 3-hydroxy-3-methylglutaryl-coenzyme A reductase reviewed - HMGCR IC50 - - -
P15127 BXGT008085 Insulin receptor reviewed - Insr IC50 - - -
P49146 BXGT010681 Neuropeptide Y receptor type 2 reviewed G-protein coupled receptor NPY2R IC50 - - -
P00720 BXGT005625 Endolysin reviewed - E Kd '=' 90900 nM
P00720 BXGT005625 Endolysin reviewed - E Delta Tm '=' 2 degrees C
P00720 BXGT005625 Endolysin reviewed - E Kd - - -
P25929 BXGT009078 Neuropeptide Y receptor type 1 reviewed G-protein coupled receptor NPY1R Ki - - -
Q16539 BXGT013634 Mitogen-activated protein kinase 14 reviewed Kinase MAPK14 Ki - - -
Q99720 BXGT019955 Sigma non-opioid intracellular receptor 1 reviewed - SIGMAR1 IC50 - - -
P15207 BXGT008096 Androgen receptor reviewed - Ar IC50 - - -
A6XA80 BXGT001522 Leukotriene C4 synthase reviewed - LTC4S IC50 - - -
P51681 BXGT010878 C-C chemokine receptor type 5 reviewed G-protein coupled receptor CCR5 Ki - - -
P25025 BXGT009006 C-X-C chemokine receptor type 2 reviewed G-protein coupled receptor CXCR2 Ki - - -
P05177 BXGT006336 Cytochrome P450 1A2 reviewed Enzyme CYP1A2 Ki - - -
P21728 BXGT008686 D(1A) dopamine receptor reviewed G-protein coupled receptor DRD1 IC50 - - -
Q9Y2D0 BXGT022229 Carbonic anhydrase 5B, mitochondrial reviewed - CA5B Ki '>' 500000 nM
P22303 BXGT008751 Acetylcholinesterase reviewed Enzyme ACHE IC50 - - -
P0DMS8 BXGT007506 Adenosine receptor A3 reviewed G-protein coupled receptor ADORA3 IC50 - - -
P22303 BXGT008751 Acetylcholinesterase reviewed Enzyme ACHE Ki - - -
P07550 BXGT006636 Beta-2 adrenergic receptor reviewed G-protein coupled receptor ADRB2 Ki - - -
P32238 BXGT009611 Cholecystokinin receptor type A reviewed G-protein coupled receptor CCKAR IC50 - - -
P33261 BXGT009707 Cytochrome P450 2C19 reviewed - CYP2C19 IC50 - - -
P33261 BXGT009707 Cytochrome P450 2C19 reviewed - CYP2C19 Ki - - -
P35367 BXGT009821 Histamine H1 receptor reviewed G-protein coupled receptor HRH1 IC50 - - -
P25021 BXGT009004 Histamine H2 receptor reviewed G-protein coupled receptor HRH2 Ki - - -
P04035 BXGT006129 3-hydroxy-3-methylglutaryl-coenzyme A reductase reviewed - HMGCR Ki - - -
P15127 BXGT008085 Insulin receptor reviewed - Insr Ki - - -
P43166 BXGT010364 Carbonic anhydrase 7 reviewed - CA7 Ki '>' 500000 nM
P08913 BXGT006841 Alpha-2A adrenergic receptor reviewed G-protein coupled receptor ADRA2A Ki - - -
P07550 BXGT006636 Beta-2 adrenergic receptor reviewed G-protein coupled receptor ADRB2 IC50 - - -
P50052 BXGT010768 Type-2 angiotensin II receptor reviewed G-protein coupled receptor AGTR2 IC50 - - -
P96878 BXGT012191 Probable transmembrane carbonic anhydrase (Carbonate dehydratase) (Carbonic dehydratase) unreviewed - Rv3273 Ki '=' 79000 nM
Q9D6N1 BXGT020260 Carbonic anhydrase 13 reviewed - Ca13 Ki '=' 697000 nM
P00720 BXGT005625 Endolysin reviewed - E Kd '=' 109000 nM
P17988 BXGT008363 Sulfotransferase 1A1 reviewed - Sult1a1 Ratio '=' 625 -
P04066 BXGT006142 Tissue alpha-L-fucosidase reviewed - FUCA1 Kii '=' 112 mM
P04150 BXGT006154 Glucocorticoid receptor reviewed Nuclear receptor NR3C1 IC50 - - -
P00720 BXGT005625 Endolysin reviewed - E Kd '=' 103000 nM
P08311 BXGT006762 Cathepsin G reviewed Enzyme CTSG Ki - - -
P18825 BXGT008426 Alpha-2C adrenergic receptor reviewed G-protein coupled receptor ADRA2C IC50 - - -
Q9NUW8 BXGT021219 Tyrosyl-DNA phosphodiesterase 1 reviewed Enzyme TDP1 Potency '=' 25118 nM
Q3I4V7 BXGT014421 Carbonic anhydrase unreviewed - CAN2 Ki '=' 25900 nM
P07943 BXGT006700 Aldo-keto reductase family 1 member B1 reviewed - Akr1b1 Ki - - -
P51679 BXGT010877 C-C chemokine receptor type 4 reviewed G-protein coupled receptor CCR4 Ki - - -
P17988 BXGT008363 Sulfotransferase 1A1 reviewed - Sult1a1 Vmax '=' 350 nM min-1
P03956 BXGT006120 Interstitial collagenase reviewed Enzyme MMP1 Ki - - -
P27361 BXGT009176 Mitogen-activated protein kinase 3 reviewed Kinase MAPK3 IC50 - - -
P06241 BXGT006429 Tyrosine-protein kinase Fyn reviewed Kinase FYN Ki - - -
P04626 BXGT006238 Receptor tyrosine-protein kinase erbB-2 reviewed Kinase ERBB2 IC50 - - -
P08575 BXGT006793 Receptor-type tyrosine-protein phosphatase C reviewed Enzyme PTPRC IC50 - - -
P03956 BXGT006120 Interstitial collagenase reviewed Enzyme MMP1 IC50 - - -
P14780 BXGT008053 Matrix metalloproteinase-9 reviewed Enzyme MMP9 Ki - - -
Q690N0 BXGT016199 Progesterone receptor unreviewed - PGR Ki - - -
Q08209 BXGT012968 Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform reviewed - PPP3CA IC50 - - -
P08575 BXGT006793 Receptor-type tyrosine-protein phosphatase C reviewed Enzyme PTPRC Ki - - -
P28564 BXGT009272 5-hydroxytryptamine receptor 1B reviewed - Htr1b IC50 - - -
P41595 BXGT010267 5-hydroxytryptamine receptor 2B reviewed G-protein coupled receptor HTR2B IC50 - - -
P31645 BXGT009558 Sodium-dependent serotonin transporter reviewed Transporter SLC6A4 IC50 - - -
P24557 BXGT008976 Thromboxane-A synthase reviewed - TBXAS1 Ki - - -
P20309 BXGT008562 Muscarinic acetylcholine receptor M3 reviewed G-protein coupled receptor CHRM3 IC50 - - -
P08912 BXGT006840 Muscarinic acetylcholine receptor M5 reviewed G-protein coupled receptor CHRM5 Ki - - -
P30988 BXGT009491 Calcitonin receptor reviewed G-protein coupled receptor CALCR Ki - - -
P19224 BXGT008468 UDP-glucuronosyltransferase 1-6 reviewed - UGT1A6 Activity '=' 1 pm/min/mg
P08913 BXGT006841 Alpha-2A adrenergic receptor reviewed G-protein coupled receptor ADRA2A IC50 - - -
P00918 BXGT005690 Carbonic anhydrase 2 reviewed - CA2 Ki - - -
P17252 BXGT008294 Protein kinase C alpha type reviewed Kinase PRKCA Ki - - -
P27361 BXGT009176 Mitogen-activated protein kinase 3 reviewed Kinase MAPK3 Ki - - -
P32241 BXGT009613 Vasoactive intestinal polypeptide receptor 1 reviewed G-protein coupled receptor VIPR1 Ki - - -
P04150 BXGT006154 Glucocorticoid receptor reviewed Nuclear receptor NR3C1 Ki - - -
P20309 BXGT008562 Muscarinic acetylcholine receptor M3 reviewed G-protein coupled receptor CHRM3 Ki - - -
P00918 BXGT005690 Carbonic anhydrase 2 reviewed - CA2 IC50 - - -
Q16236 BXGT013624 Nuclear factor erythroid 2-related factor 2 reviewed Enzyme NFE2L2 Potency - 76958 nM
P15823 BXGT008160 Alpha-1B adrenergic receptor reviewed - Adra1b Ki - - -
P13945 BXGT007972 Beta-3 adrenergic receptor reviewed G-protein coupled receptor ADRB3 IC50 - - -
P30988 BXGT009491 Calcitonin receptor reviewed G-protein coupled receptor CALCR IC50 - - -
P29477 BXGT009355 Nitric oxide synthase, inducible reviewed - Nos2 IC50 - - -
P08246 BXGT006756 Neutrophil elastase reviewed Enzyme ELANE Ki - - -
P19224 BXGT008468 UDP-glucuronosyltransferase 1-6 reviewed - UGT1A6 Activity '=' 1 pm/min/mg
P19793 BXGT008515 Retinoic acid receptor RXR-alpha reviewed Nuclear receptor RXRA Potency - 1122018 nM
Q16539 BXGT013634 Mitogen-activated protein kinase 14 reviewed Kinase MAPK14 IC50 - - -
P37288 BXGT009977 Vasopressin V1a receptor reviewed G-protein coupled receptor AVPR1A IC50 - - -
P00915 BXGT005689 Carbonic anhydrase 1 reviewed - CA1 Ki '=' 10100 nM
Q2PCB5 BXGT014154 Carbonic anhydrase unreviewed - ca Ki '=' 13700 nM
P12530 BXGT007827 Arachidonate 15-lipoxygenase reviewed - ALOX15 IC50 - - -
P08173 BXGT006738 Muscarinic acetylcholine receptor M4 reviewed G-protein coupled receptor CHRM4 Ki - - -
O42713 BXGT004563 Polyphenol oxidase 2 reviewed - PPO2 Km '=' 700000 nM
P21397 BXGT008644 Amine oxidase [flavin-containing] A reviewed - MAOA IC50 - - -
P41968 BXGT010275 Melanocortin receptor 3 reviewed G-protein coupled receptor MC3R Ki - - -
P32245 BXGT009614 Melanocortin receptor 4 reviewed G-protein coupled receptor MC4R IC50 - - -
P33032 BXGT009689 Melanocortin receptor 5 reviewed G-protein coupled receptor MC5R Ki - - -
P08912 BXGT006840 Muscarinic acetylcholine receptor M5 reviewed G-protein coupled receptor CHRM5 IC50 - - -
P41143 BXGT010223 Delta-type opioid receptor reviewed G-protein coupled receptor OPRD1 Ki - - -
P41968 BXGT010275 Melanocortin receptor 3 reviewed G-protein coupled receptor MC3R IC50 - - -
P29477 BXGT009355 Nitric oxide synthase, inducible reviewed - Nos2 Ki - - -
P32245 BXGT009614 Melanocortin receptor 4 reviewed G-protein coupled receptor MC4R Ki - - -
P43140 BXGT010360 Alpha-1A adrenergic receptor reviewed - Adra1a Ki - - -
P08588 BXGT006795 Beta-1 adrenergic receptor reviewed G-protein coupled receptor ADRB1 IC50 - - -
P10275 BXGT007552 Androgen receptor reviewed Nuclear receptor AR Potency - 223872 nM
P49146 BXGT010681 Neuropeptide Y receptor type 2 reviewed G-protein coupled receptor NPY2R Ki - - -
Q16236 BXGT013624 Nuclear factor erythroid 2-related factor 2 reviewed Enzyme NFE2L2 Potency - 1000000 nM
P29466 BXGT009349 Caspase-1 reviewed Enzyme CASP1 Ki - - -
P28335 BXGT009255 5-hydroxytryptamine receptor 2C reviewed G-protein coupled receptor HTR2C Ki - - -
P21452 BXGT008653 Substance-K receptor reviewed G-protein coupled receptor TACR2 Ki - - -
P17948 BXGT008358 Vascular endothelial growth factor receptor 1 reviewed Kinase FLT1 Ki - - -
P17252 BXGT008294 Protein kinase C alpha type reviewed Kinase PRKCA IC50 - - -
P00533 BXGT005575 Epidermal growth factor receptor reviewed Kinase EGFR IC50 - - -
P28564 BXGT009272 5-hydroxytryptamine receptor 1B reviewed - Htr1b Ki - - -
P28335 BXGT009255 5-hydroxytryptamine receptor 2C reviewed G-protein coupled receptor HTR2C IC50 - - -
P00915 BXGT005689 Carbonic anhydrase 1 reviewed - CA1 Inhibition - - -
P00720 BXGT005625 Endolysin reviewed - E Kd '=' 91000 nM
O42713 BXGT004563 Polyphenol oxidase 2 reviewed - PPO2 Kcat/Km '=' 18 /mM/s
Q12809 BXGT013267 Potassium voltage-gated channel subfamily H member 2 reviewed Ion channel KCNH2 Ki - - -
Foods  containing  the  compound
Foods
BXGF Id Food Name Scientific Name Food Group
BXGF Id Food Name Scientific Name Food Group
BXGF00019 Tarragon Artemisia dracunculus Herbs and Spices
BXGF00021 Asparagus Asparagus officinalis Vegetables
BXGF00040 Pepper (C. annuum) Capsicum annuum Vegetables
BXGF00042 Safflower Carthamus tinctorius Herbs and Spices
BXGF00051 Ceylon cinnamon Cinnamomum verum Herbs and Spices
BXGF00058 Coffee Coffea Coffee and coffee products
BXGF00068 Turmeric Curcuma longa Herbs and Spices
BXGF00090 Star anise Illicium verum Herbs and Spices
BXGF00116 Mulberry Morus Fruits
BXGF00122 Sweet marjoram Origanum majorana Herbs and Spices
BXGF00168 Winter savory Satureja montana Herbs and Spices
BXGF00170 Sesame Sesamum orientale Herbs and Spices
BXGF00173 Garden tomato (var.) Solanum lycopersicum var. lycopersicum Vegetables
BXGF00180 Tamarind Tamarindus indica Fruits
BXGF00191 Highbush blueberry Vaccinium corymbosum Fruits
BXGF00193 Bilberry Vaccinium myrtillus Fruits
BXGF00194 Lingonberry Vaccinium vitis-idaea Fruits
BXGF00206 Ginger Zingiber officinale Herbs and Spices
BXGF00641 Cocoa powder Cocoa and cocoa products
BXGF00829 Green bell pepper Capsicum annuum Vegetables
BXGF00830 Yellow bell pepper Capsicum annuum Vegetables
BXGF00831 Orange bell pepper Capsicum annuum Vegetables
BXGF00832 Red bell pepper Capsicum annuum Vegetables
BXGF01185 Aloe vera Aloe vera Medicinal Plant
BXGF01237 Magnolia obovata Magnolia obovata Medicinal Plant
BXGF01338 Amsinckia menziesii Amsinckia menziesii Others
BXGF01597 Senegalia catechu Senegalia catechu Medicinal Plant
BXGF01721 Humulus lupulus Humulus lupulus Medicinal Plant
BXGF01798 Melaleuca uncinata Melaleuca uncinata Others
BXGF01833 Hakea saligna Hakea saligna Others
BXGF01900 Aloe ferox Aloe ferox Medicinal Plant
BXGF02024 Actaea dahurica Actaea dahurica Human Edible Plant
BXGF02049 Angelica sinensis Angelica sinensis Medicinal Plant
BXGF02143 Actaea cimicifuga Actaea cimicifuga Medicinal Plant
BXGF02182 Atractylodes lancea Atractylodes lancea Medicinal Plant
BXGF02204 Apocynum venetum Apocynum venetum Medicinal Plant
BXGF02330 Codonopsis pilosula Codonopsis pilosula Medicinal Plant
BXGF02553 Avrainvillea nigricans Avrainvillea nigricans Others
BXGF02620 Rosa chinensis Rosa chinensis Medicinal Plant
BXGF02639 Rhododendron ferrugineum Rhododendron ferrugineum Human Edible Plant
BXGF02713 Drypetes roxburghii Drypetes roxburghii Medicinal Plant
BXGF02825 Buddleja variabilis Buddleja variabilis Others
BXGF02937 Senecio scandens Senecio scandens Medicinal Plant
BXGF03001 Vallaris solanacea Vallaris solanacea Medicinal Plant
BXGF03065 Mentha pulegiformis Mentha pulegiformis Others
BXGF03096 Salvia nubicola Salvia nubicola Human Edible Plant
BXGF03125 Grindelia nana Grindelia nana Others
BXGF03162 Atractylodes macrocephala Atractylodes macrocephala Medicinal Plant
BXGF03170 Haloxylon salicornicum Haloxylon salicornicum Medicinal Plant
BXGF03229 Leucanthemum maximum Leucanthemum maximum Others
BXGF03249 Vitex trifolia Vitex trifolia Medicinal Plant
BXGF03281 Calea megacephala Calea megacephala Others
BXGF03323 Abies nobilis Abies nobilis Others
BXGF03345 Persea indica Persea indica Medicinal Plant
BXGF03369 Corydalis cornuta Corydalis cornuta Others
BXGF03401 Disepalum plagioneurum Disepalum plagioneurum Others
BXGF03418 Piper aequale Piper aequale Medicinal Plant
BXGF03427 Phellodendron chinense Phellodendron chinense Medicinal Plant
BXGF03430 Alkanna hirsutissima Alkanna hirsutissima Others
BXGF03448 Pinus picea Pinus picea Others
BXGF03466 Picris radicata Picris radicata Others
BXGF03479 Bombax ceiba Bombax ceiba Medicinal Plant
BXGF03525 Acrocomia sclerocarpa Acrocomia sclerocarpa Others
BXGF03540 Eremophila serrulata Eremophila serrulata Others
BXGF03550 Rodgersia podophylla Rodgersia podophylla Medicinal Plant
BXGF03566 Delphinium campylocentrum Delphinium campylocentrum Others
BXGF03574 Cordyline indivisa Cordyline indivisa Medicinal Plant
BXGF03588 Primula hirsuta Primula hirsuta Others
BXGF03604 Jasminum grandiflorum Jasminum grandiflorum Medicinal Plant
BXGF03611 Viscum coloratum Viscum coloratum Medicinal Plant
BXGF03828 Phellodendron amurense Phellodendron amurense Medicinal Plant
BXGF04087 Erysimum odoratum Erysimum odoratum Others
BXGF04092 Heterotheca inuloides Heterotheca inuloides Medicinal Plant
BXGF04098 Delphinium andersoni Delphinium andersoni Others
BXGF04126 Vismia jefensis Vismia jefensis Others
BXGF04142 Angelica tarokoensis Angelica tarokoensis Others
BXGF04147 Swertia delavayi Swertia delavayi Others
BXGF04165 Epimedium davidii Epimedium davidii Medicinal Plant
BXGF04168 Globba malaccensis Globba malaccensis Medicinal Plant
BXGF04175 Diphasia angolensis Diphasia angolensis Others
BXGF04182 Knightia excelsa Knightia excelsa Medicinal Plant
BXGF04199 Isodon japonicus Isodon japonicus Medicinal Plant
BXGF04207 Solanum acaule Solanum acaule Others
BXGF04209 Chaenomeles sinensis Chaenomeles sinensis Medicinal Plant
BXGF04216 Frullania tamarisci Frullania tamarisci Others
BXGF04221 Alangium premnifolium Alangium premnifolium Others
BXGF04233 Saussurea carthamoides Saussurea carthamoides Others
BXGF04250 Galenia africana Galenia africana Medicinal Plant
BXGF04256 Phellodendron chinese Phellodendron chinese Others
BXGF04264 Micromeria pineolens Micromeria pineolens Others
BXGF04269 Gnidia lamprantha Gnidia lamprantha Medicinal Plant
BXGF04276 Ilex amara Ilex amara Others
BXGF04283 Terminalia chebula Terminalia chebula Medicinal Plant
BXGF04295 Leonurus glaucescens Leonurus glaucescens Medicinal Plant
BXGF04342 Salacia madagascariensis Salacia madagascariensis Human Edible Plant
BXGF04343 Maba buxifolia Maba buxifolia Medicinal Plant
BXGF04402 Actaea simplex Actaea simplex Others
BXGF04631 Aloe spicata Aloe spicata Medicinal Plant
BXGF04777 Quercus sessiliflora Quercus sessiliflora Others
BXGF04909 Hippophae fructus Hippophae fructus Others
BXGF04926 Aloe africana Aloe africana Medicinal Plant
BXGF05011 Artemisia capillaries Artemisia capillaries Others
BXGF05041 Desmodium styracifolium Desmodium styracifolium Medicinal Plant
BXGF05264 Magnolia officinalis Magnolia officinalis Medicinal Plant
BXGF05462 Campsis flos Campsis flos Others
BXGF05480 Lepidium draba Lepidium draba Medicinal Plant
BXGF05563 Phegopteris bukoensis Phegopteris bukoensis Others
BXGF05842 Platycodon grandiforus Platycodon grandiforus Others
BXGF05921 Scapania nemorea Scapania nemorea Others
The  compound-realted  diseases
Diseases
BXGD Id Disease Name CUI Disease Id Disease Class Name Number of targets?Number of targets related to compound connecting disease, higher numbers indicate the compound is more associated with the disease