adisease

Showing entry for Cooley's anemia

General Disease Information
BXGD Id	BXGD000135
Disease Name	Cooley's anemia
Disease CUI Id	C0002875
MeSH Codes	C16 C15
Disease Class Name	Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Hemic and Lymphatic Diseases
Semantic Type	Disease or Syndrome
Human Phenotype Ontology Id
Human Phenotype Ontology Term
Disease Ontology Id	DOID:630
Disease Ontology Class Name	genetic disease
Disorder Network	disorder-protein-compound-food associations

The disease-related target proteins

Proteins

Uniport Id	BXGT Id	Protein Name	Gene	Status	Protein Class
Uniport Id	BXGT Id	Protein name	Gene	Status	Protein class
O00767	BXGT003949	Acyl-CoA desaturase	6319	reviewed
O14746	BXGT004091	Telomerase reverse transcriptase	7015	reviewed	Enzyme
O14788	BXGT004100	Tumor necrosis factor ligand superfamily member 11	8600	reviewed	Signaling
O14980	BXGT004119	Exportin-1	7514	reviewed	Receptor
O43524	BXGT004599	Forkhead box protein O3	2309	reviewed
O60656	BXGT004889	UDP-glucuronosyltransferase 1-9	54600	reviewed
O60701	BXGT004894	UDP-glucose 6-dehydrogenase	7358	reviewed
O60760	BXGT004899	Hematopoietic prostaglandin D synthase	27306	reviewed
O95180	BXGT005358	Voltage-dependent T-type calcium channel subunit alpha-1H	8912	reviewed	Ion channel
P00367	BXGT005517	Glutamate dehydrogenase 1, mitochondrial	2746	reviewed	Enzyme
P00450	BXGT005544	Ceruloplasmin	1356	reviewed	Enzyme
P00734	BXGT005630	Prothrombin	2147	reviewed	Enzyme
P01011	BXGT005715	Alpha-1-antichymotrypsin	12	reviewed	Enzyme modulator
P01137	BXGT005737	Transforming growth factor beta-1 proprotein	7040	reviewed	Signaling
P01189	BXGT005742	Pro-opiomelanocortin	5443	reviewed
P01270	BXGT005746	Parathyroid hormone	5741	reviewed
P01375	BXGT005753	Tumor necrosis factor	7124	reviewed	Signaling
P02649	BXGT005909	Apolipoprotein E	348	reviewed
P02724	BXGT005934	Glycophorin-A	2993	reviewed
P02741	BXGT005936	C-reactive protein	1401	reviewed
P02768	BXGT005955	Serum albumin	213	reviewed	Transporter
P02786	BXGT005961	Transferrin receptor protein 1	7037	reviewed	Enzyme
P03372	BXGT006059	Estrogen receptor	2099	reviewed	Nuclear receptor
P05181	BXGT006337	Cytochrome P450 2E1	1571	reviewed
P07225	BXGT006572	Vitamin K-dependent protein S	5627	reviewed
P08174	BXGT006739	Complement decay-accelerating factor	1604	reviewed
P08246	BXGT006756	Neutrophil elastase	1991	reviewed	Enzyme
P08263	BXGT006759	Glutathione S-transferase A1	2938	reviewed
P08684	BXGT006812	Cytochrome P450 3A4	1576	reviewed	Enzyme
P08700	BXGT006816	Interleukin-3	3562	reviewed
P08887	BXGT006835	Interleukin-6 receptor subunit alpha	3570	reviewed	Signaling
P09488	BXGT006899	Glutathione S-transferase Mu 1	2944	reviewed
P09651	BXGT006913	Heterogeneous nuclear ribonucleoprotein A1	3178	reviewed
P11172	BXGT007665	Uridine 5'-monophosphate synthase	7372	reviewed
P11473	BXGT007709	Vitamin D3 receptor	7421	reviewed	Nuclear receptor
P11498	BXGT007714	Pyruvate carboxylase, mitochondrial	5091	reviewed	Enzyme
P15692	BXGT008147	Vascular endothelial growth factor A	7422	reviewed	Signaling
P19224	BXGT008468	UDP-glucuronosyltransferase 1-6	54578	reviewed
P22309	BXGT008753	UDP-glucuronosyltransferase 1-1	54658	reviewed
P22310	BXGT008754	UDP-glucuronosyltransferase 1-4	54657	reviewed
P23786	BXGT008906	Carnitine O-palmitoyltransferase 2, mitochondrial	1376	reviewed	Enzyme
P24298	BXGT008960	Alanine aminotransferase 1	2875	reviewed	Enzyme
P25791	BXGT009072	Rhombotin-2	4005	reviewed
P27708	BXGT009202	CAD protein	790	reviewed	Enzyme
P28072	BXGT009231	Proteasome subunit beta type-6	5694	reviewed
P28907	BXGT009301	ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1	952	reviewed	Enzyme
P29474	BXGT009352	Nitric oxide synthase, endothelial	4846	reviewed
P30044	BXGT009395	Peroxiredoxin-5, mitochondrial	25824	reviewed
P30711	BXGT009460	Glutathione S-transferase theta-1	2952	reviewed
P32119	BXGT009600	Peroxiredoxin-2	7001	reviewed	Enzyme
P34932	BXGT009772	Heat shock 70 kDa protein 4	3308	reviewed
P35503	BXGT009840	UDP-glucuronosyltransferase 1-3	54659	reviewed
P42898	BXGT010344	Methylenetetrahydrofolate reductase	4524	reviewed
P50416	BXGT010797	Carnitine O-palmitoyltransferase 1, liver isoform	1374	reviewed	Enzyme
P52209	BXGT010923	6-phosphogluconate dehydrogenase, decarboxylating	5226	reviewed	Enzyme
P55774	BXGT011124	C-C motif chemokine 18	6362	reviewed	Signaling
P63261	BXGT011512	Actin, cytoplasmic 2	71	reviewed	Cellular structure
P68871	BXGT011615	Hemoglobin subunit beta	3043	reviewed
P69891	BXGT011646	Hemoglobin subunit gamma-1	3047	reviewed
P69892	BXGT011647	Hemoglobin subunit gamma-2	3048	reviewed
P69905	BXGT011649	Hemoglobin subunit alpha	3040	reviewed
P80188	BXGT011882	Neutrophil gelatinase-associated lipocalin	3934	reviewed	Enzyme
P81172	BXGT011935	Hepcidin	57817	reviewed
Q02127	BXGT012635	Dihydroorotate dehydrogenase (quinone), mitochondrial	1723	reviewed	Enzyme
Q06830	BXGT012894	Peroxiredoxin-1	5052	reviewed	Enzyme
Q13118	BXGT013312	Krueppel-like factor 10	7071	reviewed	Nucleic acid binding
Q13231	BXGT013329	Chitotriosidase-1	1118	reviewed
Q13938	BXGT013405	Calcyphosin	828	reviewed
Q30201	BXGT014297	Hereditary hemochromatosis protein	3077	reviewed
Q6ZVN8	BXGT016641	Hemojuvelin	148738	reviewed
Q8NER1	BXGT018556	Transient receptor potential cation channel subfamily V member 1	7442	reviewed	Ion channel
Q96IY4	BXGT019678	Carboxypeptidase B2	1361	reviewed	Enzyme
Q9HAW7	BXGT020508	UDP-glucuronosyltransferase 1-7	54577	reviewed
Q9HAW8	BXGT020509	UDP-glucuronosyltransferase 1-10	54575	reviewed
Q9HAW9	BXGT020510	UDP-glucuronosyltransferase 1-8	54576	reviewed
Q9NZD4	BXGT021271	Alpha-hemoglobin-stabilizing protein	51327	reviewed	Chaperone
Q9Y2Q3	BXGT022242	Glutathione S-transferase kappa 1	373156	reviewed
Q9Y2S2	BXGT022245	Lambda-crystallin homolog	51084	reviewed	Enzyme
O60502	BXGT023392	Protein O-GlcNAcase	10724	reviewed

The disease-related compounds

Compounds

BXGC Id	Compound Name	Structure	Molecular Weight	Number of targets^{?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease}

The disease-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compounds in food^{?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease}