Showing entry for Psoriasis vulgaris


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Disease Information
BXGD IdBXGD005292
Disease NamePsoriasis vulgaris
Disease CUI IdC0263361
MeSH Codes C17  
Disease Class NameSkin and Connective Tissue Diseases
Semantic TypeDisease or Syndrome
Human Phenotype Ontology Id   
Human Phenotype Ontology Term
Disease Ontology Id   
Disease Ontology Class Name
Disorder Network disorder-protein-compound-food associations
The  disease-related  target proteins
Proteins
Uniport Id BXGT Id Protein Name Gene Status Protein Class
Uniport Id BXGT Id Protein name Gene Status Protein class
O00182 BXGT003889 Galectin-9 3965 reviewed Signaling
O00206 BXGT003894 Toll-like receptor 4 7099 reviewed
O15123 BXGT004130 Angiopoietin-2 285 reviewed Signaling
O43157 BXGT004572 Plexin-B1 5364 reviewed
O43813 BXGT004628 Glutathione S-transferase LANCL1 10314 reviewed
O60603 BXGT004887 Toll-like receptor 2 7097 reviewed
O60760 BXGT004899 Hematopoietic prostaglandin D synthase 27306 reviewed
O75015 BXGT005095 Low affinity immunoglobulin gamma Fc region receptor III-B 2215 reviewed Cell adhesion
O75116 BXGT005100 Rho-associated protein kinase 2 9475 reviewed Kinase
O75369 BXGT005119 Filamin-B 2317 reviewed
O75469 BXGT005128 Nuclear receptor subfamily 1 group I member 2 8856 reviewed Nuclear receptor
O75475 BXGT005130 PC4 and SFRS1-interacting protein 11168 reviewed Signaling
O76054 BXGT005172 SEC14-like protein 2 23541 reviewed
O95150 BXGT005351 Tumor necrosis factor ligand superfamily member 15 9966 reviewed Signaling
P00740 BXGT005634 Coagulation factor IX 2158 reviewed Enzyme
P01133 BXGT005736 Pro-epidermal growth factor 1950 reviewed
P01137 BXGT005737 Transforming growth factor beta-1 proprotein 7040 reviewed Signaling
P01236 BXGT005744 Prolactin 5617 reviewed Signaling
P01375 BXGT005753 Tumor necrosis factor 7124 reviewed Signaling
P01579 BXGT005770 Interferon gamma 3458 reviewed
P01584 BXGT005772 Interleukin-1 beta 3553 reviewed
P01589 BXGT005773 Interleukin-2 receptor subunit alpha 3559 reviewed Receptor
P01889 BXGT005809 HLA class I histocompatibility antigen, B-7 alpha chain 3106 reviewed
P01909 BXGT005815 HLA class II histocompatibility antigen, DQ alpha 1 chain 3117 reviewed Immune response
P01911 BXGT005816 HLA class II histocompatibility antigen, DRB1-15 beta chain 3123 reviewed Immune response
P01920 BXGT005817 HLA class II histocompatibility antigen, DQ beta 1 chain 3119 reviewed Immune response
P02649 BXGT005909 Apolipoprotein E 348 reviewed
P02741 BXGT005936 C-reactive protein 1401 reviewed
P04040 BXGT006132 Catalase 847 reviewed Enzyme
P04440 BXGT006216 HLA class II histocompatibility antigen, DP beta 1 chain 3115 reviewed Immune response
P05107 BXGT006316 Integrin beta-2 3689 reviewed Receptor
P05231 BXGT006345 Interleukin-6 3569 reviewed
P07225 BXGT006572 Vitamin K-dependent protein S 5627 reviewed
P07288 BXGT006591 Prostate-specific antigen 354 reviewed Enzyme
P07602 BXGT006646 Prosaposin 5660 reviewed
P08473 BXGT006773 Neprilysin 4311 reviewed Enzyme
P08865 BXGT006832 40S ribosomal protein SA 3921 reviewed Nucleic acid binding
P08922 BXGT006843 Proto-oncogene tyrosine-protein kinase ROS 6098 reviewed Kinase
P09601 BXGT006909 Heme oxygenase 1 3162 reviewed
P10145 BXGT007542 Interleukin-8 3576 reviewed Signaling
P10415 BXGT007567 Apoptosis regulator Bcl-2 596 reviewed Signaling
P11021 BXGT007644 Endoplasmic reticulum chaperone BiP 3309 reviewed
P11166 BXGT007661 Solute carrier family 2, facilitated glucose transporter member 1 6513 reviewed Transporter
P11473 BXGT007709 Vitamin D3 receptor 7421 reviewed Nuclear receptor
P13500 BXGT007916 C-C motif chemokine 2 6347 reviewed Signaling
P13501 BXGT007917 C-C motif chemokine 5 6352 reviewed Signaling
P14174 BXGT007991 Macrophage migration inhibitory factor 4282 reviewed
P14780 BXGT008053 Matrix metalloproteinase-9 4318 reviewed Enzyme
P14921 BXGT008068 Protein C-ets-1 2113 reviewed Transcription factor
P16410 BXGT008224 Cytotoxic T-lymphocyte protein 4 1493 reviewed
P17931 BXGT008356 Galectin-3 3958 reviewed Signaling
P19838 BXGT008526 Nuclear factor NF-kappa-B p105 subunit 4790 reviewed Transcription factor
P20702 BXGT008592 Integrin alpha-X 3687 reviewed
P20930 BXGT008616 Filaggrin 2312 reviewed Cellular structure
P21580 BXGT008666 Tumor necrosis factor alpha-induced protein 3 7128 reviewed Enzyme
P22607 BXGT008784 Fibroblast growth factor receptor 3 2261 reviewed Kinase
P23560 BXGT008883 Brain-derived neurotrophic factor 627 reviewed Signaling
P24385 BXGT008965 G1/S-specific cyclin-D1 595 reviewed Enzyme modulator
P26951 BXGT009147 Interleukin-3 receptor subunit alpha 3563 reviewed Signaling
P28482 BXGT009263 Mitogen-activated protein kinase 1 5594 reviewed Kinase
P29017 BXGT009305 T-cell surface glycoprotein CD1c 911 reviewed
P29033 BXGT009308 Gap junction beta-2 protein 2706 reviewed Cell-cell junction
P29460 BXGT009348 Interleukin-12 subunit beta 3593 reviewed Signaling
P29597 BXGT009367 Non-receptor tyrosine-protein kinase TYK2 7297 reviewed Kinase
P30532 BXGT009433 Neuronal acetylcholine receptor subunit alpha-5 1138 reviewed Ion channel
P31151 BXGT009510 Protein S100-A7 6278 reviewed Calcium-binding protein
P31645 BXGT009558 Sodium-dependent serotonin transporter 6532 reviewed Transporter
P35228 BXGT009800 Nitric oxide synthase, inducible 4843 reviewed
P35869 BXGT009877 Aryl hydrocarbon receptor 196 reviewed Transcription factor
P36222 BXGT009914 Chitinase-3-like protein 1 1116 reviewed
P37231 BXGT009972 Peroxisome proliferator-activated receptor gamma 5468 reviewed Nuclear receptor
P40933 BXGT010209 Interleukin-15 3600 reviewed
P41597 BXGT010268 C-C chemokine receptor type 2 729230 reviewed
P42330 BXGT010301 Aldo-keto reductase family 1 member C3 8644 reviewed Enzyme
P42574 BXGT010317 Caspase-3 836 reviewed Enzyme
P42898 BXGT010344 Methylenetetrahydrofolate reductase 4524 reviewed
P46531 BXGT010526 Neurogenic locus notch homolog protein 1 4851 reviewed
P48061 BXGT010616 Stromal cell-derived factor 1 6387 reviewed
P48637 BXGT010649 Glutathione synthetase 2937 reviewed Enzyme
P49908 BXGT010760 Selenoprotein P 6414 reviewed Extracellular structure
P49913 BXGT010761 Cathelicidin antimicrobial peptide 820 reviewed
P50591 BXGT010814 Tumor necrosis factor ligand superfamily member 10 8743 reviewed Signaling
P51449 BXGT010846 Nuclear receptor ROR-gamma 6097 reviewed Nuclear receptor
P51665 BXGT010874 26S proteasome non-ATPase regulatory subunit 7 5713 reviewed Enzyme
P51679 BXGT010877 C-C chemokine receptor type 4 1233 reviewed G-protein coupled receptor
P51681 BXGT010878 C-C chemokine receptor type 5 1234 reviewed G-protein coupled receptor
P51684 BXGT010880 C-C chemokine receptor type 6 1235 reviewed G-protein coupled receptor
P51878 BXGT010902 Caspase-5 838 reviewed Enzyme
P55040 BXGT011099 GTP-binding protein GEM 2669 reviewed
P55085 BXGT011104 Proteinase-activated receptor 2 2150 reviewed G-protein coupled receptor
P55786 BXGT011125 Puromycin-sensitive aminopeptidase 9520 reviewed Enzyme
P60022 BXGT011285 Beta-defensin 1 1672 reviewed
P68036 BXGT011572 Ubiquitin-conjugating enzyme E2 L3 7332 reviewed Enzyme
P80188 BXGT011882 Neutrophil gelatinase-associated lipocalin 3934 reviewed Enzyme
Q03518 BXGT012723 Antigen peptide transporter 1 6890 reviewed Transporter
Q04721 BXGT012777 Neurogenic locus notch homolog protein 2 4853 reviewed
Q05901 BXGT012842 Neuronal acetylcholine receptor subunit beta-3 1142 reviewed Ion channel
Q07812 BXGT012940 Apoptosis regulator BAX 581 reviewed Signaling
Q07955 BXGT012951 Serine/arginine-rich splicing factor 1 6426 reviewed Nucleic acid binding
Q13546 BXGT013372 Receptor-interacting serine/threonine-protein kinase 1 8737 reviewed Kinase
Q13555 BXGT013375 Calcium/calmodulin-dependent protein kinase type II subunit gamma 818 reviewed Kinase
Q15389 BXGT013564 Angiopoietin-1 284 reviewed Signaling
Q15825 BXGT013603 Neuronal acetylcholine receptor subunit alpha-6 8973 reviewed Ion channel
Q16236 BXGT013624 Nuclear factor erythroid 2-related factor 2 4780 reviewed Enzyme
Q5VWK5 BXGT015891 Interleukin-23 receptor 149233 reviewed Signaling
Q5Y7D3 BXGT015912 HLA class II histocompatibility antigen DQ beta chain 3119 unreviewed
Q6P179 BXGT016440 Endoplasmic reticulum aminopeptidase 2 64167 reviewed Enzyme
Q8IU57 BXGT018332 Interferon lambda receptor 1 163702 reviewed Receptor
Q8WTT0 BXGT018987 C-type lectin domain family 4 member C 170482 reviewed Receptor
Q96AZ6 BXGT019621 Interferon-stimulated gene 20 kDa protein 3669 reviewed
Q96P20 BXGT019704 NACHT, LRR and PYD domains-containing protein 3 114548 reviewed
Q96PD4 BXGT019705 Interleukin-17F 112744 reviewed
Q99735 BXGT019957 Microsomal glutathione S-transferase 2 4258 reviewed Enzyme
Q9BQI3 BXGT020113 Eukaryotic translation initiation factor 2-alpha kinase 1 27102 reviewed Kinase
Q9BXL7 BXGT020171 Caspase recruitment domain-containing protein 11 84433 reviewed
Q9BXR0 BXGT020173 Queuine tRNA-ribosyltransferase catalytic subunit 1 81890 reviewed
Q9BZS1 BXGT020203 Forkhead box protein P3 50943 reviewed
Q9C000 BXGT020206 NACHT, LRR and PYD domains-containing protein 1 22861 reviewed
Q9GZX6 BXGT020428 Interleukin-22 50616 reviewed
Q9HBE5 BXGT020518 Interleukin-21 receptor 50615 reviewed Receptor
Q9HC29 BXGT020526 Nucleotide-binding oligomerization domain-containing protein 2 64127 reviewed Enzyme
Q9NZ08 BXGT021266 Endoplasmic reticulum aminopeptidase 1 51752 reviewed Enzyme
Q9P0Z9 BXGT021294 Peroxisomal sarcosine oxidase 51268 reviewed Enzyme
Q9UJ71 BXGT021725 C-type lectin domain family 4 member K 50489 reviewed Receptor
Q9ULJ6 BXGT021761 Zinc finger MIZ domain-containing protein 1 57178 reviewed
Q9Y2Q3 BXGT022242 Glutathione S-transferase kappa 1 373156 reviewed
Q9Y2R2 BXGT022243 Tyrosine-protein phosphatase non-receptor type 22 26191 reviewed
Q9Y617 BXGT022314 Phosphoserine aminotransferase 29968 reviewed
P04439 BXGT022649 HLA class I histocompatibility antigen, A-3 alpha chain 3105 reviewed
Q16552 BXGT023419 Interleukin-17A 3605 reviewed
Q96QC4 BXGT023878 MHC class I polypeptide-related sequence A 100507436 unreviewed
Q7Z6A9 BXGT025024 B- and T-lymphocyte attenuator 151888 reviewed
The  disease-related  compounds
Compounds
BXGC Id Compound Name Structure Molecular Weight Number of targets?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease
The  disease-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compounds in food?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease