Showing entry for Prediabetes syndrome


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Disease Information
BXGD IdBXGD007959
Disease NamePrediabetes syndrome
Disease CUI IdC0362046
MeSH Codes C18   C19  
Disease Class NameNutritional and Metabolic Diseases; Endocrine System Diseases
Semantic TypeDisease or Syndrome
Human Phenotype Ontology Id   
Human Phenotype Ontology Term
Disease Ontology Id DOID:0014667  
Disease Ontology Class Namedisease of metabolism
Disorder Network disorder-protein-compound-food associations
The  disease-related  target proteins
Proteins
Uniport Id BXGT Id Protein Name Gene Status Protein Class
Uniport Id BXGT Id Protein name Gene Status Protein class
O00206 BXGT003894 Toll-like receptor 4 7099 reviewed
O14788 BXGT004100 Tumor necrosis factor ligand superfamily member 11 8600 reviewed Signaling
O14842 BXGT004106 Free fatty acid receptor 1 2864 reviewed G-protein coupled receptor
O60603 BXGT004887 Toll-like receptor 2 7097 reviewed
P00450 BXGT005544 Ceruloplasmin 1356 reviewed Enzyme
P00813 BXGT005667 Adenosine deaminase 100 reviewed Enzyme
P01019 BXGT005717 Angiotensinogen 183 reviewed Enzyme modulator
P01112 BXGT005732 GTPase HRas 3265 reviewed Enzyme modulator
P01137 BXGT005737 Transforming growth factor beta-1 proprotein 7040 reviewed Signaling
P01236 BXGT005744 Prolactin 5617 reviewed Signaling
P01270 BXGT005746 Parathyroid hormone 5741 reviewed
P01275 BXGT005747 Glucagon 2641 reviewed
P01308 BXGT005749 Insulin 3630 reviewed
P01375 BXGT005753 Tumor necrosis factor 7124 reviewed Signaling
P01579 BXGT005770 Interferon gamma 3458 reviewed
P01903 BXGT005814 HLA class II histocompatibility antigen, DR alpha chain 3122 reviewed Immune response
P02741 BXGT005936 C-reactive protein 1401 reviewed
P02753 BXGT005945 Retinol-binding protein 4 5950 reviewed Transporter
P02765 BXGT005952 Alpha-2-HS-glycoprotein 197 reviewed Enzyme modulator
P02768 BXGT005955 Serum albumin 213 reviewed Transporter
P02818 BXGT005969 Osteocalcin 632 reviewed
P04040 BXGT006132 Catalase 847 reviewed Enzyme
P04275 BXGT006180 von Willebrand factor 7450 reviewed Enzyme modulator
P04278 BXGT006182 Sex hormone-binding globulin 6462 reviewed
P04632 BXGT006241 Calpain small subunit 1 826 reviewed
P04746 BXGT006256 Pancreatic alpha-amylase 279 reviewed
P05067 BXGT006306 Amyloid-beta precursor protein 351 reviewed Enzyme modulator
P05121 BXGT006320 Plasminogen activator inhibitor 1 5054 reviewed Enzyme modulator
P05164 BXGT006333 Myeloperoxidase 4353 reviewed Enzyme
P05231 BXGT006345 Interleukin-6 3569 reviewed
P06753 BXGT006498 Tropomyosin alpha-3 chain 7170 reviewed Cellular structure
P08581 BXGT006794 Hepatocyte growth factor receptor 4233 reviewed Kinase
P10997 BXGT007643 Islet amyloid polypeptide 3375 reviewed Signaling
P11021 BXGT007644 Endoplasmic reticulum chaperone BiP 3309 reviewed
P11166 BXGT007661 Solute carrier family 2, facilitated glucose transporter member 1 6513 reviewed Transporter
P11226 BXGT007675 Mannose-binding protein C 4153 reviewed Receptor
P11597 BXGT007727 Cholesteryl ester transfer protein 1071 reviewed
P13501 BXGT007917 C-C motif chemokine 5 6352 reviewed Signaling
P13726 BXGT007950 Tissue factor 2152 reviewed Receptor
P14210 BXGT007994 Hepatocyte growth factor 3082 reviewed Enzyme
P14672 BXGT008037 Solute carrier family 2, facilitated glucose transporter member 4 6517 reviewed Transporter
P14735 BXGT008042 Insulin-degrading enzyme 3416 reviewed Enzyme
P15692 BXGT008147 Vascular endothelial growth factor A 7422 reviewed Signaling
P16442 BXGT008227 Histo-blood group ABO system transferase 28 reviewed Enzyme
P16671 BXGT008255 Platelet glycoprotein 4 948 reviewed Receptor
P17861 BXGT008348 X-box-binding protein 1 7494 reviewed
P17931 BXGT008356 Galectin-3 3958 reviewed Signaling
P18850 BXGT008433 Cyclic AMP-dependent transcription factor ATF-6 alpha 22926 reviewed
P19883 BXGT008528 Follistatin 10468 reviewed Enzyme modulator
P22894 BXGT008815 Neutrophil collagenase 4317 reviewed Enzyme
P23560 BXGT008883 Brain-derived neurotrophic factor 627 reviewed Signaling
P24298 BXGT008960 Alanine aminotransferase 1 2875 reviewed Enzyme
P25311 BXGT009036 Zinc-alpha-2-glycoprotein 563 reviewed
P27487 BXGT009187 Dipeptidyl peptidase 4 1803 reviewed Enzyme
P27708 BXGT009202 CAD protein 790 reviewed Enzyme
P29965 BXGT009388 CD40 ligand 959 reviewed Signaling
P30556 BXGT009441 Type-1 angiotensin II receptor 185 reviewed G-protein coupled receptor
P30988 BXGT009491 Calcitonin receptor 799 reviewed G-protein coupled receptor
P31639 BXGT009556 Sodium/glucose cotransporter 2 6524 reviewed Transporter
P34998 BXGT009781 Corticotropin-releasing factor receptor 1 1394 reviewed
P35270 BXGT009807 Sepiapterin reductase 6697 reviewed
P35555 BXGT009845 Fibrillin-1 2200 reviewed Calcium-binding protein
P35557 BXGT009846 Glucokinase 2645 reviewed Kinase
P35610 BXGT009855 Sterol O-acyltransferase 1 6646 reviewed Enzyme
P35869 BXGT009877 Aryl hydrocarbon receptor 196 reviewed Transcription factor
P36222 BXGT009914 Chitinase-3-like protein 1 1116 reviewed
P36956 BXGT009947 Sterol regulatory element-binding protein 1 6720 reviewed
P37231 BXGT009972 Peroxisome proliferator-activated receptor gamma 5468 reviewed Nuclear receptor
P40933 BXGT010209 Interleukin-15 3600 reviewed
P41235 BXGT010241 Hepatocyte nuclear factor 4-alpha 3172 reviewed Nuclear receptor
P43220 BXGT010367 Glucagon-like peptide 1 receptor 2740 reviewed G-protein coupled receptor
P43652 BXGT010405 Afamin 173 reviewed Transporter
P45983 BXGT010494 Mitogen-activated protein kinase 8 5599 reviewed Kinase
P48061 BXGT010616 Stromal cell-derived factor 1 6387 reviewed
P49286 BXGT010691 Melatonin receptor type 1B 4544 reviewed G-protein coupled receptor
P55769 BXGT011123 NHP2-like protein 1 4809 reviewed Nucleic acid binding
P60709 BXGT011322 Actin, cytoplasmic 1 60 reviewed Cellular structure
P81172 BXGT011935 Hepcidin 57817 reviewed
Q05329 BXGT012814 Glutamate decarboxylase 2 2572 reviewed Enzyme
Q05940 BXGT012846 Synaptic vesicular amine transporter 6571 reviewed Transporter
Q13285 BXGT013335 Steroidogenic factor 1 2516 reviewed Nuclear receptor
Q14116 BXGT013442 Interleukin-18 3606 reviewed
Q14654 BXGT013495 ATP-sensitive inward rectifier potassium channel 11 3767 reviewed Ion channel
Q15118 BXGT013540 [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial 5163 reviewed Kinase
Q15848 BXGT013609 Adiponectin 9370 reviewed
Q16665 BXGT013653 Hypoxia-inducible factor 1-alpha 3091 reviewed Transcription factor
Q5VZ30 BXGT015894 Glutamate decarboxylase 2 (Pancreatic islets and brain, 65kDa) 2572 unreviewed
Q76LX8 BXGT016870 A disintegrin and metalloproteinase with thrombospondin motifs 13 11093 reviewed Enzyme
Q8IVA8 BXGT018342 Glutamate decarboxylase 1 (Brain, 67kDa) 2571 unreviewed
Q8N6T7 BXGT018525 NAD-dependent protein deacetylase sirtuin-6 51548 reviewed Epigenetic regulator
Q8NBP7 BXGT018541 Proprotein convertase subtilisin/kexin type 9 255738 reviewed Enzyme
Q8WZ42 BXGT019023 Titin 7273 reviewed Kinase
Q92932 BXGT019395 Receptor-type tyrosine-protein phosphatase N2 5799 reviewed
Q96QV1 BXGT019722 Hedgehog-interacting protein 64399 reviewed
Q99259 BXGT019915 Glutamate decarboxylase 1 2571 reviewed Enzyme
Q9BXJ0 BXGT020169 Complement C1q tumor necrosis factor-related protein 5 114902 reviewed
Q9BZR6 BXGT020202 Reticulon-4 receptor 65078 reviewed
Q9C0B1 BXGT020209 Alpha-ketoglutarate-dependent dioxygenase FTO 79068 reviewed
Q9GZX6 BXGT020428 Interleukin-22 50616 reviewed
Q9H9B1 BXGT020501 Histone-lysine N-methyltransferase EHMT1 79813 reviewed Epigenetic regulator
Q9NR96 BXGT021181 Toll-like receptor 9 54106 reviewed
Q9NTG7 BXGT021211 NAD-dependent protein deacetylase sirtuin-3, mitochondrial 23410 reviewed Epigenetic regulator
Q9NZJ5 BXGT021275 Eukaryotic translation initiation factor 2-alpha kinase 3 9451 reviewed Kinase
Q9UM07 BXGT021771 Protein-arginine deiminase type-4 23569 reviewed
Q9Y6L6 BXGT022334 Solute carrier organic anion transporter family member 1B1 10599 reviewed Transporter
O75976 BXGT022954 Carboxypeptidase D 1362 reviewed
Q9UKG1 BXGT022975 DCC-interacting protein 13-alpha 26060 reviewed
O14793 BXGT023280 Growth/differentiation factor 8 2660 reviewed Signaling
O95140 BXGT024482 Mitofusin-2 9927 reviewed Enzyme
Q9Y6M1 BXGT025468 Insulin-like growth factor 2 mRNA-binding protein 2 10644 reviewed Enzyme
The  disease-related  compounds
Compounds
BXGC Id Compound Name Structure Molecular Weight Number of targets?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease
The  disease-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compounds in food?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease