Showing entry for Leucine-rich glioma-inactivated protein 1


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT005409
Protein NameLeucine-rich glioma-inactivated protein 1
Uniport IdO95970
GeneLGI1
Gene Id9211
DomainEPTP; LRR_8
Pfam PF03736   PF13855  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0007411 axon guidance
Biological Process GO:0007399 nervous system development
Biological Process GO:0031175 neuron projection development
Biological Process GO:0099645 neurotransmitter receptor localization to postsynaptic specialization membrane
Biological Process GO:0030307 positive regulation of cell growth
Biological Process GO:0050806 positive regulation of synaptic transmission
molecular function GO:0005102 signaling receptor binding
cellular component GO:0005576 extracellular region
cellular component GO:0005615 extracellular space
cellular component GO:0098978 glutamatergic synapse
Reactome
Pathway Id Pathway Name
R-HSA-1266738 Developmental Biology
R-HSA-5682910 LGI-ADAM interactions
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0002622 BXGD000119 Amnesia Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
C0002963 BXGD000161 Angina Pectoris, Variant Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0004114 BXGD000255 Astrocytoma Neoplasms
C0004364 BXGD000270 Autoimmune Diseases Immune System Diseases
C0006118 BXGD000372 Brain Neoplasms Neoplasms; Nervous System Diseases
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0007131 BXGD000441 Non-Small Cell Lung Carcinoma Neoplasms; Respiratory Tract Diseases
C0007758 BXGD000475 Cerebellar Ataxia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0008489 BXGD000546 Chorea Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0009241 BXGD000595 Cognition Disorders Mental Disorders
C0009952 BXGD000639 Febrile Convulsions Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0011570 BXGD000729 Mental Depression Behavior and Behavior Mechanisms
C0011581 BXGD000733 Depressive disorder Mental Disorders
C0012833 BXGD000795 Dizziness Pathological Conditions, Signs and Symptoms
C0013384 BXGD000826 Dyskinetic syndrome Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0014038 BXGD000878 Encephalitis Nervous System Diseases
C0014544 BXGD000926 Epilepsy Nervous System Diseases
C0014547 BXGD000927 Epilepsies, Partial Nervous System Diseases
C0014548 BXGD000928 Epilepsy, Generalized Nervous System Diseases
C0014549 BXGD000929 Tonic-Clonic Epilepsy Nervous System Diseases
C0014556 BXGD000932 Epilepsy, Temporal Lobe Nervous System Diseases
C0017636 BXGD001131 Glioblastoma Neoplasms
C0017638 BXGD001132 Glioma Neoplasms
C0020625 BXGD001451 Hyponatremia Nutritional and Metabolic Diseases
C0023860 BXGD001708 Listeriosis Infections
C0026650 BXGD001913 Movement Disorders Nervous System Diseases
C0026896 BXGD001946 Myasthenia Gravis Neoplasms; Immune System Diseases; Nervous System Diseases
C0027626 BXGD002005 Neoplasm Invasiveness Pathological Conditions, Signs and Symptoms; Neoplasms
C0027627 BXGD002006 Neoplasm Metastasis Pathological Conditions, Signs and Symptoms; Neoplasms
C0027651 BXGD002009 Neoplasms Neoplasms
C0027709 BXGD002026 Nephrocalcinosis Nutritional and Metabolic Diseases; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0027721 BXGD002029 Lipoid nephrosis Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0027765 BXGD002033 nervous system disorder Nervous System Diseases
C0027819 BXGD002043 Neuroblastoma Neoplasms
C0030193 BXGD002191 Pain Pathological Conditions, Signs and Symptoms
C0033975 BXGD002447 Psychotic Disorders Mental Disorders
C0036572 BXGD002625 Seizures Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0037763 BXGD002699 Spasm Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0040100 BXGD002840 Thymoma Neoplasms; Hemic and Lymphatic Diseases
C0042571 BXGD002991 Vertigo Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Otorhinolaryngologic Diseases
C0085584 BXGD003195 Encephalopathies Nervous System Diseases
C0085633 BXGD003216 Mood swings Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
C0086132 BXGD003264 Depressive Symptoms Behavior and Behavior Mechanisms
C0149958 BXGD003395 Complex partial seizures Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0153633 BXGD003674 Malignant neoplasm of brain Neoplasms; Nervous System Diseases
C0233401 BXGD004575 Psychiatric symptom
C0233514 BXGD004584 Abnormal behavior Behavior and Behavior Mechanisms
C0233794 BXGD004618 Memory impairment Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Behavior and Behavior Mechanisms
C0234461 BXGD004669 aphasic
C0234533 BXGD004687 Generalized seizures Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0234974 BXGD004706 Simple Partial Seizures Nervous System Diseases
C0235946 BXGD004789 Cerebral atrophy Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0242287 BXGD005145 Isaacs syndrome Musculoskeletal Diseases; Nervous System Diseases
C0270816 BXGD006110 epilepsy and migraine
C0270834 BXGD006114 Complex partial seizure with impairment of consciousness Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0270850 BXGD006117 Idiopathic generalized epilepsy Nervous System Diseases
C0276226 BXGD006408 Herpes encephalitis Infections; Nervous System Diseases
C0278878 BXGD006609 Adult Glioblastoma Neoplasms
C0279626 BXGD006657 Squamous cell carcinoma of esophagus Digestive System Diseases; Neoplasms
C0280474 BXGD006748 Childhood Glioblastoma Neoplasms
C0334583 BXGD007124 Pilocytic Astrocytoma Neoplasms
C0338430 BXGD007173 Limbic Encephalitis Neoplasms; Infections; Nervous System Diseases
C0338656 BXGD007211 Impaired cognition Mental Disorders
C0344315 BXGD007666 Depressed mood Behavior and Behavior Mechanisms
C0346957 BXGD007836 Disseminated Malignant Neoplasm Neoplasms
C0349204 BXGD007892 Nonorganic psychosis Mental Disorders
C0391957 BXGD008019 idiopathic epilepsy
C0391958 BXGD008020 Familial Epilepsies Nervous System Diseases
C0393588 BXGD008100 Dystonia, Paroxysmal Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0393639 BXGD008110 Hashimoto's encephalitis Nervous System Diseases; Endocrine System Diseases
C0393682 BXGD008117 Epilepsy, Lateral Temporal Nervous System Diseases
C0424101 BXGD008519 Inattention
C0424295 BXGD008524 Hyperactive behavior Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0431380 BXGD008680 Cortical Dysplasia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0442874 BXGD008814 Neuropathy Nervous System Diseases
C0454578 BXGD008839 Receptive aphasia (finding) Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0494475 BXGD009030 Tonic - clonic seizures Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0497327 BXGD009061 Dementia Nervous System Diseases; Mental Disorders
C0542476 BXGD009276 Forgetful Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
C0555198 BXGD009432 Malignant Glioma Neoplasms
C0684219 BXGD009789 Myokymia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0686619 BXGD009835 Secondary malignant neoplasm of lymph node Pathological Conditions, Signs and Symptoms; Neoplasms
C0700095 BXGD009875 Central neuroblastoma Neoplasms; Nervous System Diseases
C0751112 BXGD010320 Subclinical Seizure Nervous System Diseases
C0751295 BXGD010383 Memory Loss Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Behavior and Behavior Mechanisms
C0751495 BXGD010473 Seizures, Focal Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0751919 BXGD010643 Acquired Neuromyotonia Musculoskeletal Diseases; Nervous System Diseases
C0851578 BXGD010925 Sleep Disorders Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders
C0877017 BXGD011329 Generalized tonic-clonic seizures with focal onset Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0949664 BXGD011583 Tauopathies Nervous System Diseases
C1263846 BXGD011897 Attention deficit hyperactivity disorder Mental Disorders
C1269955 BXGD012005 Tumor Cell Invasion
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C1512694 BXGD013193 Increased Cellularity Present
C1527366 BXGD013280 Salaam Seizures Nervous System Diseases
C1562113 BXGD013372 Fleck corneal dystrophy Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases
C1611743 BXGD013456 Familial (FPAH)
C1621958 BXGD013468 Glioblastoma Multiforme Neoplasms
C1838062 BXGD014292 Autosomal Dominant Lateral Temporal Lobe Epilepsy Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders
C1838063 BXGD014293 Focal sensory auditory seizure Nervous System Diseases
C1842564 BXGD014524 Temporal epilepsy, familial Nervous System Diseases
C1847651 BXGD014881 Rapidly progressive dementia Nervous System Diseases; Mental Disorders
C1850765 BXGD015176 Visual auras Nervous System Diseases
C1857276 BXGD015688 Trichohepatoenteric Syndrome Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Skin and Connective Tissue Diseases
C1858477 BXGD015797 Epilepsy, Partial, with Variable Foci Nervous System Diseases
C2930824 BXGD017898 Autoimmune limbic encephalitis Neoplasms; Infections; Immune System Diseases; Nervous System Diseases
C2939419 BXGD018178 Secondary Neoplasm Pathological Conditions, Signs and Symptoms; Neoplasms
C2986717 BXGD018241 Anti-N-Methyl-D-Aspartate Receptor Encephalitis Neoplasms; Immune System Diseases; Nervous System Diseases
C3854373 BXGD019829 Morvan syndrome Nervous System Diseases
C4049182 BXGD021914 Idiopathic partial epilepsy
C4082937 BXGD022095 Necrotizing enterocolitis in fetus OR newborn Digestive System Diseases
C4086165 BXGD022126 Childhood Neuroblastoma Neoplasms
C4285807 BXGD022455 Behavioral and psychological symptoms of dementia
C4317109 BXGD022725 Epileptic Seizures Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C4505072 BXGD022953 Epileptic Syndromes Nervous System Diseases
C4551584 BXGD023362 Brain atrophy Nervous System Diseases
C4551957 BXGD023448 Epilepsy, Familial Temporal Lobe 1 Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders
C4706583 BXGD023702 Limbic encephalitis with leucine-rich glioma-inactivated 1 antibodies Neoplasms; Infections; Nervous System Diseases; Endocrine System Diseases
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0002586 Calcium 40.08
BXGC0018397 beta-1,4-mannan 180.06
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein