Showing entry for Epilepsy, Generalized


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Disease Information
BXGD IdBXGD000928
Disease NameEpilepsy, Generalized
Disease CUI IdC0014548
MeSH Codes C10  
Disease Class NameNervous System Diseases
Semantic TypeDisease or Syndrome
Human Phenotype Ontology Id   
Human Phenotype Ontology Term
Disease Ontology Id DOID:7  
Disease Ontology Class Namedisease of anatomical entity
Disorder Network disorder-protein-compound-food associations
The  disease-related  target proteins
Proteins
Uniport Id BXGT Id Protein Name Gene Status Protein Class
Uniport Id BXGT Id Protein name Gene Status Protein class
O00305 BXGT003907 Voltage-dependent L-type calcium channel subunit beta-4 785 reviewed Ion channel
O00555 BXGT003936 Voltage-dependent P/Q-type calcium channel subunit alpha-1A 773 reviewed Ion channel
O14764 BXGT004094 Gamma-aminobutyric acid receptor subunit delta 2563 reviewed Ion channel
O43497 BXGT004596 Voltage-dependent T-type calcium channel subunit alpha-1G 8913 reviewed Ion channel
O60741 BXGT004897 Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 348980 reviewed
O75311 BXGT005109 Glycine receptor subunit alpha-3 8001 reviewed Ion channel
O76039 BXGT005171 Cyclin-dependent kinase-like 5 6792 reviewed Kinase
O76054 BXGT005172 SEC14-like protein 2 23541 reviewed
O95180 BXGT005358 Voltage-dependent T-type calcium channel subunit alpha-1H 8912 reviewed Ion channel
O95970 BXGT005409 Leucine-rich glioma-inactivated protein 1 9211 reviewed
P01303 BXGT005748 Pro-neuropeptide Y 4852 reviewed Signaling
P01584 BXGT005772 Interleukin-1 beta 3553 reviewed
P04818 BXGT006269 Thymidylate synthase 7298 reviewed Enzyme
P08183 BXGT006741 ATP-dependent translocase ABCB1 5243 reviewed Transporter
P09429 BXGT006889 High mobility group protein B1 3146 reviewed Nucleic acid binding
P11166 BXGT007661 Solute carrier family 2, facilitated glucose transporter member 1 6513 reviewed Transporter
P11169 BXGT007664 Solute carrier family 2, facilitated glucose transporter member 3 6515 reviewed Transporter
P13637 BXGT007933 Sodium/potassium-transporting ATPase subunit alpha-3 478 reviewed Transporter
P14867 BXGT008061 Gamma-aminobutyric acid receptor subunit alpha-1 2554 reviewed Ion channel
P17787 BXGT008341 Neuronal acetylcholine receptor subunit beta-2 1141 reviewed Ion channel
P18507 BXGT008411 Gamma-aminobutyric acid receptor subunit gamma-2 2566 reviewed Ion channel
P22894 BXGT008815 Neutrophil collagenase 4317 reviewed Enzyme
P23368 BXGT008856 NAD-dependent malic enzyme, mitochondrial 4200 reviewed Enzyme
P23378 BXGT008859 Glycine dehydrogenase (decarboxylating), mitochondrial 2731 reviewed Enzyme
P23946 BXGT008932 Chymase 1215 reviewed Enzyme
P28472 BXGT009260 Gamma-aminobutyric acid receptor subunit beta-3 2562 reviewed Ion channel
P30531 BXGT009432 Sodium- and chloride-dependent GABA transporter 1 6529 reviewed Transporter
P35372 BXGT009823 Mu-type opioid receptor 4988 reviewed G-protein coupled receptor
P35498 BXGT009838 Sodium channel protein type 1 subunit alpha 6323 reviewed Ion channel
P36544 BXGT009926 Neuronal acetylcholine receptor subunit alpha-7 89832 reviewed
P43681 BXGT010407 Neuronal acetylcholine receptor subunit alpha-4 1137 reviewed Ion channel
P46108 BXGT010509 Adapter molecule crk 1398 reviewed
P47869 BXGT010590 Gamma-aminobutyric acid receptor subunit alpha-2 2555 reviewed Ion channel
P48167 BXGT010621 Glycine receptor subunit beta 2743 reviewed Ion channel
P50993 BXGT010826 Sodium/potassium-transporting ATPase subunit alpha-2 477 reviewed Transporter
P51649 BXGT010872 Succinate-semialdehyde dehydrogenase, mitochondrial 7915 reviewed Enzyme
P53985 BXGT011022 Monocarboxylate transporter 1 6566 reviewed Transporter
P54098 BXGT011030 DNA polymerase subunit gamma-1 5428 reviewed Enzyme
P78508 BXGT011845 ATP-sensitive inward rectifier potassium channel 10 3766 reviewed Ion channel
Q03518 BXGT012723 Antigen peptide transporter 1 6890 reviewed Transporter
Q05193 BXGT012810 Dynamin-1 1759 reviewed Enzyme modulator
Q05329 BXGT012814 Glutamate decarboxylase 2 2572 reviewed Enzyme
Q12791 BXGT013264 Calcium-activated potassium channel subunit alpha-1 3778 reviewed Ion channel
Q12879 BXGT013275 Glutamate receptor ionotropic, NMDA 2A 2903 reviewed Ion channel
Q13002 BXGT013303 Glutamate receptor ionotropic, kainate 2 2898 reviewed Ion channel
Q13510 BXGT013367 Acid ceramidase 427 reviewed Enzyme
Q14654 BXGT013495 ATP-sensitive inward rectifier potassium channel 11 3767 reviewed Ion channel
Q14833 BXGT013508 Metabotropic glutamate receptor 4 2914 reviewed G-protein coupled receptor
Q15262 BXGT013555 Receptor-type tyrosine-protein phosphatase kappa 5796 reviewed Enzyme
Q16881 BXGT013688 Thioredoxin reductase 1, cytoplasmic 7296 reviewed Enzyme
Q5VZ30 BXGT015894 Glutamate decarboxylase 2 (Pancreatic islets and brain, 65kDa) 2572 unreviewed
Q8IVS2 BXGT018349 Malonyl-CoA-acyl carrier protein transacylase, mitochondrial 27349 reviewed
Q92887 BXGT019389 Canalicular multispecific organic anion transporter 1 1244 reviewed Transporter
Q96PU5 BXGT019711 E3 ubiquitin-protein ligase NEDD4-like 23327 reviewed Enzyme
Q99250 BXGT019913 Sodium channel protein type 2 subunit alpha 6326 reviewed Ion channel
Q9NWB1 BXGT021231 RNA binding protein fox-1 homolog 1 54715 reviewed Nucleic acid binding
Q9NY47 BXGT021249 Voltage-dependent calcium channel subunit alpha-2/delta-2 9254 reviewed Ion channel
Q9P0X4 BXGT021293 Voltage-dependent T-type calcium channel subunit alpha-1I 8911 reviewed Ion channel
Q9UL51 BXGT021754 Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 610 reviewed Ion channel
Q9ULC4 BXGT021757 Malignant T-cell-amplified sequence 1 28985 reviewed Receptor
P00738 BXGT022874 Haptoglobin 3240 reviewed Enzyme
Q05086 BXGT025648 Ubiquitin-protein ligase E3A 7337 reviewed
The  disease-related  compounds
Compounds
BXGC Id Compound Name Structure Molecular Weight Number of targets?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease
The  disease-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compounds in food?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease