adisease

Showing entry for Gait abnormality

General Disease Information
BXGD Id	BXGD009512
Disease Name	Gait abnormality
Disease CUI Id	C0575081
MeSH Codes	C23 C10
Disease Class Name	Pathological Conditions, Signs and Symptoms; Nervous System Diseases
Semantic Type	Finding
Human Phenotype Ontology Id	HP:0000707
Human Phenotype Ontology Term	Abnormality of the nervous system
Disease Ontology Id
Disease Ontology Class Name
Disorder Network	disorder-protein-compound-food associations

The disease-related target proteins

Proteins

Uniport Id	BXGT Id	Protein Name	Gene	Status	Protein Class
Uniport Id	BXGT Id	Protein name	Gene	Status	Protein class
A0A024RAV5	BXGT000013	V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog, isoform CRA_b	3845	unreviewed
O00206	BXGT003894	Toll-like receptor 4	7099	reviewed
O00429	BXGT003919	Dynamin-1-like protein	10059	reviewed	Enzyme modulator
O14656	BXGT004080	Torsin-1A	1861	reviewed	Chaperone
O14764	BXGT004094	Gamma-aminobutyric acid receptor subunit delta	2563	reviewed	Ion channel
O14936	BXGT004114	Peripheral plasma membrane protein CASK	8573	reviewed	Kinase
O15553	BXGT004181	Pyrin	4210	reviewed
O43914	BXGT004635	TYRO protein tyrosine kinase-binding protein	7305	reviewed
O60260	BXGT004864	E3 ubiquitin-protein ligase parkin	5071	reviewed	Enzyme
O60313	BXGT004871	Dynamin-like 120 kDa protein, mitochondrial	4976	reviewed	Enzyme modulator
O75112	BXGT005099	LIM domain-binding protein 3	11155	reviewed	Cellular structure
O75530	BXGT005135	Polycomb protein EED	8726	reviewed
O75899	BXGT005161	Gamma-aminobutyric acid type B receptor subunit 2	9568	reviewed	G-protein coupled receptor
O94907	BXGT005340	Dickkopf-related protein 1	22943	reviewed
O95263	BXGT005366	High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B	8622	reviewed
O95278	BXGT005370	Laforin	7957	reviewed
O95622	BXGT005386	Adenylate cyclase type 5	111	reviewed
O95831	BXGT005399	Apoptosis-inducing factor 1, mitochondrial	9131	reviewed	Enzyme
P01116	BXGT005733	GTPase KRas	3845	reviewed	Enzyme modulator
P01889	BXGT005809	HLA class I histocompatibility antigen, B-7 alpha chain	3106	reviewed
P02458	BXGT005879	Collagen alpha-1(II) chain	1280	reviewed
P02545	BXGT005889	Prelamin-A/C	4000	reviewed
P02792	BXGT005966	Ferritin light chain	2512	reviewed	Storage
P04062	BXGT006140	Lysosomal acid glucosylceramidase	2629	reviewed
P04350	BXGT006193	Tubulin beta-4A chain	10382	reviewed	Cellular structure
P05067	BXGT006306	Amyloid-beta precursor protein	351	reviewed	Enzyme modulator
P07510	BXGT006631	Acetylcholine receptor subunit gamma	1146	reviewed	Ion channel
P07902	BXGT006697	Galactose-1-phosphate uridylyltransferase	2592	reviewed	Enzyme
P08034	BXGT006716	Gap junction beta-1 protein	2705	reviewed	Cell-cell junction
P08253	BXGT006757	72 kDa type IV collagenase	4313	reviewed	Enzyme
P09619	BXGT006911	Platelet-derived growth factor receptor beta	5159	reviewed	Kinase
P10275	BXGT007552	Androgen receptor	367	reviewed	Nuclear receptor
P10636	BXGT007596	Microtubule-associated protein tau	4137	reviewed
P11362	BXGT007693	Fibroblast growth factor receptor 1	2260	reviewed	Kinase
P11473	BXGT007709	Vitamin D3 receptor	7421	reviewed	Nuclear receptor
P15289	BXGT008102	Arylsulfatase A	410	reviewed	Enzyme
P16278	BXGT008213	Beta-galactosidase	2720	reviewed	Enzyme
P20807	BXGT008601	Calpain-3	825	reviewed	Enzyme
P21333	BXGT008638	Filamin-A	2316	reviewed
P21817	BXGT008693	Ryanodine receptor 1	6261	reviewed	Ion channel
P22314	BXGT008755	Ubiquitin-like modifier-activating enzyme 1	7317	reviewed	Enzyme
P23415	BXGT008864	Glycine receptor subunit alpha-1	2741	reviewed	Ion channel
P30793	BXGT009466	GTP cyclohydrolase 1	2643	reviewed	Enzyme
P32004	BXGT009594	Neural cell adhesion molecule L1	3897	reviewed
P35219	BXGT009797	Carbonic anhydrase-related protein	767	reviewed
P35222	BXGT009799	Catenin beta-1	1499	reviewed
P35499	BXGT009839	Sodium channel protein type 4 subunit alpha	6329	reviewed	Ion channel
P36894	BXGT009939	Bone morphogenetic protein receptor type-1A	657	reviewed	Kinase
P37173	BXGT009970	TGF-beta receptor type-2	7048	reviewed	Kinase
P40337	BXGT010174	von Hippel-Lindau disease tumor suppressor	7428	reviewed	Enzyme
P40692	BXGT010195	DNA mismatch repair protein Mlh1	4292	reviewed	Nucleic acid binding
P42336	BXGT010302	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	5290	reviewed	Kinase
P42345	BXGT010304	Serine/threonine-protein kinase mTOR	2475	reviewed	Kinase
P42898	BXGT010344	Methylenetetrahydrofolate reductase	4524	reviewed
P43246	BXGT010371	DNA mismatch repair protein Msh2	4436	reviewed	Nucleic acid binding
P45452	BXGT010462	Collagenase 3	4322	reviewed	Enzyme
P48029	BXGT010606	Sodium- and chloride-dependent creatine transporter 1	6535	reviewed	Transporter
P48167	BXGT010621	Glycine receptor subunit beta	2743	reviewed	Ion channel
P48643	BXGT010650	T-complex protein 1 subunit epsilon	22948	reviewed	Chaperone
P49638	BXGT010720	Alpha-tocopherol transfer protein	7274	reviewed	Transporter
P49747	BXGT010732	Cartilage oligomeric matrix protein	1311	reviewed
P49768	BXGT010740	Presenilin-1	5663	reviewed	Enzyme
P49792	BXGT010743	E3 SUMO-protein ligase RanBP2	5903	reviewed	Enzyme modulator
P51812	BXGT010893	Ribosomal protein S6 kinase alpha-3	6197	reviewed	Kinase
P52701	BXGT010943	DNA mismatch repair protein Msh6	2956	reviewed	Nucleic acid binding
P54098	BXGT011030	DNA polymerase subunit gamma-1	5428	reviewed	Enzyme
P54278	BXGT011038	Mismatch repair endonuclease PMS2	5395	reviewed	Nucleic acid binding
P54886	BXGT011092	Delta-1-pyrroline-5-carboxylate synthase	5832	reviewed	Enzyme
P55072	BXGT011103	Transitional endoplasmic reticulum ATPase	7415	reviewed
P60891	BXGT011337	Ribose-phosphate pyrophosphokinase 1	5631	reviewed	Kinase
P61011	BXGT011346	Signal recognition particle 54 kDa protein	6729	reviewed	Nucleic acid binding
P98155	BXGT012226	Very low-density lipoprotein receptor	7436	reviewed
P98160	BXGT012228	Basement membrane-specific heparan sulfate proteoglycan core protein	3339	reviewed	Enzyme modulator
Q01453	BXGT012588	Peripheral myelin protein 22	5376	reviewed	Cellular structure
Q02809	BXGT012674	Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1	5351	reviewed	Enzyme
Q04206	BXGT012754	Transcription factor p65	5970	reviewed	Transcription factor
Q04446	BXGT012764	1,4-alpha-glucan-branching enzyme	2632	reviewed	Enzyme
Q13144	BXGT013317	Translation initiation factor eIF-2B subunit epsilon	8893	reviewed
Q13303	BXGT013336	Voltage-gated potassium channel subunit beta-2	8514	reviewed	Ion channel
Q13315	BXGT013339	Serine-protein kinase ATM	472	reviewed	Kinase
Q13501	BXGT013365	Sequestosome-1	8878	reviewed
Q13510	BXGT013367	Acid ceramidase	427	reviewed	Enzyme
Q13627	BXGT013385	Dual specificity tyrosine-phosphorylation-regulated kinase 1A	1859	reviewed	Kinase
Q14204	BXGT013456	Cytoplasmic dynein 1 heavy chain 1	1778	reviewed	Enzyme
Q14232	BXGT013457	Translation initiation factor eIF-2B subunit alpha	1967	reviewed
Q15067	BXGT013532	Peroxisomal acyl-coenzyme A oxidase 1	51	reviewed	Enzyme
Q16828	BXGT013676	Dual specificity protein phosphatase 6	1848	reviewed
Q2M1P5	BXGT014129	Kinesin-like protein KIF7	374654	reviewed
Q5VWK5	BXGT015891	Interleukin-23 receptor	149233	reviewed	Signaling
Q7Z2E3	BXGT017246	Aprataxin	54840	reviewed	Nucleic acid binding
Q86SX6	BXGT017601	Glutaredoxin-related protein 5, mitochondrial	51218	reviewed	Enzyme
Q8WZA1	BXGT019024	Protein O-linked-mannose beta-1,2-N-acetylglucosaminyltransferase 1	55624	reviewed
Q92743	BXGT019368	Serine protease HTRA1	5654	reviewed	Enzyme
Q96EQ8	BXGT019652	E3 ubiquitin-protein ligase RNF125	54941	reviewed
Q99519	BXGT019928	Sialidase-1	4758	reviewed	Enzyme
Q99707	BXGT019952	Methionine synthase	4548	reviewed
Q99720	BXGT019955	Sigma non-opioid intracellular receptor 1	10280	reviewed
Q9BV79	BXGT020141	Enoyl-[acyl-carrier-protein] reductase, mitochondrial	51102	reviewed
Q9BVA1	BXGT020142	Tubulin beta-2B chain	347733	reviewed
Q9BZ23	BXGT020194	Pantothenate kinase 2, mitochondrial	80025	reviewed	Kinase
Q9HBA0	BXGT020516	Transient receptor potential cation channel subfamily V member 4	59341	reviewed	Ion channel
Q9NQX3	BXGT021172	Gephyrin	10243	reviewed
Q9NRR6	BXGT021193	Phosphatidylinositol polyphosphate 5-phosphatase type IV	56623	reviewed
Q9NZ08	BXGT021266	Endoplasmic reticulum aminopeptidase 1	51752	reviewed	Enzyme
Q9NZ09	BXGT021267	Ubiquitin-associated protein 1	51271	reviewed
Q9NZJ5	BXGT021275	Eukaryotic translation initiation factor 2-alpha kinase 3	9451	reviewed	Kinase
Q9UBK8	BXGT021655	Methionine synthase reductase	4552	reviewed
Q9UM47	BXGT021772	Neurogenic locus notch homolog protein 3	4854	reviewed
Q9Y223	BXGT022207	Bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase	10020	reviewed	Enzyme
Q9Y2M0	BXGT022241	Fanconi-associated nuclease 1	22909	reviewed
Q9Y6K9	BXGT022333	NF-kappa-B essential modulator	8517	reviewed	Kinase
P43146	BXGT022852	Netrin receptor DCC	1630	reviewed
P35240	BXGT022927	Merlin	4771	reviewed
Q8IYW5	BXGT023493	E3 ubiquitin-protein ligase RNF168	165918	reviewed
O95140	BXGT024482	Mitofusin-2	9927	reviewed	Enzyme
Q9H9S5	BXGT024623	Fukutin-related protein	79147	reviewed
P51608	BXGT025073	Methyl-CpG-binding protein 2	4204	reviewed	Epigenetic regulator

The disease-related compounds

Compounds

BXGC Id	Compound Name	Structure	Molecular Weight	Number of targets^{?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease}

The disease-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compounds in food^{?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease}