adisease

Showing entry for Lymphadenopathy

General Disease Information
BXGD Id	BXGD009053
Disease Name	Lymphadenopathy
Disease CUI Id	C0497156
MeSH Codes	C15
Disease Class Name	Hemic and Lymphatic Diseases
Semantic Type	Disease or Syndrome
Human Phenotype Ontology Id	HP:0002715 HP:0001626
Human Phenotype Ontology Term	Abnormality of the immune system; Abnormality of the cardiovascular system
Disease Ontology Id
Disease Ontology Class Name
Disorder Network	disorder-protein-compound-food associations

The disease-related target proteins

Proteins

Uniport Id	BXGT Id	Protein Name	Gene	Status	Protein Class
Uniport Id	BXGT Id	Protein name	Gene	Status	Protein class
A0A024RAV5	BXGT000013	V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog, isoform CRA_b	3845	unreviewed
O00206	BXGT003894	Toll-like receptor 4	7099	reviewed
O00329	BXGT003909	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform	5293	reviewed	Kinase
O14786	BXGT004099	Neuropilin-1	8829	reviewed
O14788	BXGT004100	Tumor necrosis factor ligand superfamily member 11	8600	reviewed	Signaling
O15553	BXGT004181	Pyrin	4210	reviewed
O60674	BXGT004892	Tyrosine-protein kinase JAK2	3717	reviewed	Kinase
O75914	BXGT005165	Serine/threonine-protein kinase PAK 3	5063	reviewed	Kinase
O95255	BXGT005363	Multidrug resistance-associated protein 6	368	reviewed	Transporter
O95407	BXGT005380	Tumor necrosis factor receptor superfamily member 6B	8771	reviewed
O95477	BXGT005383	Phospholipid-transporting ATPase ABCA1	19	reviewed	Transporter
P00533	BXGT005575	Epidermal growth factor receptor	1956	reviewed	Kinase
P00734	BXGT005630	Prothrombin	2147	reviewed	Enzyme
P00736	BXGT005632	Complement C1r subcomponent	715	reviewed	Enzyme
P00813	BXGT005667	Adenosine deaminase	100	reviewed	Enzyme
P01024	BXGT005719	Complement C3	718	reviewed	Enzyme modulator
P01116	BXGT005733	GTPase KRas	3845	reviewed	Enzyme modulator
P01270	BXGT005746	Parathyroid hormone	5741	reviewed
P01375	BXGT005753	Tumor necrosis factor	7124	reviewed	Signaling
P01579	BXGT005770	Interferon gamma	3458	reviewed
P01589	BXGT005773	Interleukin-2 receptor subunit alpha	3559	reviewed	Receptor
P01889	BXGT005809	HLA class I histocompatibility antigen, B-7 alpha chain	3106	reviewed
P01911	BXGT005816	HLA class II histocompatibility antigen, DRB1-15 beta chain	3123	reviewed	Immune response
P02647	BXGT005908	Apolipoprotein A-I	335	reviewed
P02741	BXGT005936	C-reactive protein	1401	reviewed
P02768	BXGT005955	Serum albumin	213	reviewed	Transporter
P02786	BXGT005961	Transferrin receptor protein 1	7037	reviewed	Enzyme
P03372	BXGT006059	Estrogen receptor	2099	reviewed	Nuclear receptor
P04180	BXGT006164	Phosphatidylcholine-sterol acyltransferase	3931	reviewed	Enzyme
P04637	BXGT006243	Cellular tumor antigen p53	7157	reviewed	Transcription factor
P04839	BXGT006273	Cytochrome b-245 heavy chain	1536	reviewed	Ion channel
P05154	BXGT006327	Plasma serine protease inhibitor	5104	reviewed	Enzyme modulator
P05161	BXGT006331	Ubiquitin-like protein ISG15	9636	reviewed	Nucleic acid binding
P05187	BXGT006339	Alkaline phosphatase, placental type	250	reviewed	Enzyme
P05231	BXGT006345	Interleukin-6	3569	reviewed
P05362	BXGT006350	Intercellular adhesion molecule 1	3383	reviewed
P06731	BXGT006488	Carcinoembryonic antigen-related cell adhesion molecule 5	1048	reviewed
P06734	BXGT006491	Low affinity immunoglobulin epsilon Fc receptor	2208	reviewed	Receptor
P06748	BXGT006497	Nucleophosmin	4869	reviewed	Chaperone
P07949	BXGT006703	Proto-oncogene tyrosine-protein kinase receptor Ret	5979	reviewed	Kinase
P08246	BXGT006756	Neutrophil elastase	1991	reviewed	Enzyme
P08473	BXGT006773	Neprilysin	4311	reviewed	Enzyme
P08575	BXGT006793	Receptor-type tyrosine-protein phosphatase C	5788	reviewed	Enzyme
P10276	BXGT007553	Retinoic acid receptor alpha	5914	reviewed	Nuclear receptor
P10323	BXGT007557	Acrosin	49	reviewed	Enzyme
P10415	BXGT007567	Apoptosis regulator Bcl-2	596	reviewed	Signaling
P10644	BXGT007597	cAMP-dependent protein kinase type I-alpha regulatory subunit	5573	reviewed
P10747	BXGT007609	T-cell-specific surface glycoprotein CD28	940	reviewed
P12821	BXGT007849	Angiotensin-converting enzyme	1636	reviewed	Enzyme
P13051	BXGT007877	Uracil-DNA glycosylase	7374	reviewed
P13612	BXGT007928	Integrin alpha-4	3676	reviewed
P14151	BXGT007990	L-selectin	6402	reviewed
P14174	BXGT007991	Macrophage migration inhibitory factor	4282	reviewed
P14598	BXGT008024	Neutrophil cytosol factor 1	653361	reviewed
P14784	BXGT008054	Interleukin-2 receptor subunit beta	3560	reviewed	Receptor
P15692	BXGT008147	Vascular endothelial growth factor A	7422	reviewed	Signaling
P16278	BXGT008213	Beta-galactosidase	2720	reviewed	Enzyme
P16410	BXGT008224	Cytotoxic T-lymphocyte protein 4	1493	reviewed
P16871	BXGT008269	Interleukin-7 receptor subunit alpha	3575	reviewed	Receptor
P17405	BXGT008304	Sphingomyelin phosphodiesterase	6609	reviewed	Enzyme
P17931	BXGT008356	Galectin-3	3958	reviewed	Signaling
P18827	BXGT008427	Syndecan-1	6382	reviewed	Extracellular structure
P19438	BXGT008480	Tumor necrosis factor receptor superfamily member 1A	7132	reviewed
P19544	BXGT008494	Wilms tumor protein	7490	reviewed	Nucleic acid binding
P19838	BXGT008526	Nuclear factor NF-kappa-B p105 subunit	4790	reviewed	Transcription factor
P21589	BXGT008669	5'-nucleotidase	4907	reviewed	Enzyme
P24385	BXGT008965	G1/S-specific cyclin-D1	595	reviewed	Enzyme modulator
P27797	BXGT009206	Calreticulin	811	reviewed	Calcium-binding protein
P28070	BXGT009230	Proteasome subunit beta type-4	5692	reviewed
P28907	BXGT009301	ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1	952	reviewed	Enzyme
P31785	BXGT009577	Cytokine receptor common subunit gamma	3561	reviewed	Signaling
P32302	BXGT009619	C-X-C chemokine receptor type 5	643	reviewed	G-protein coupled receptor
P33991	BXGT009745	DNA replication licensing factor MCM4	4173	reviewed	Enzyme
P37173	BXGT009970	TGF-beta receptor type-2	7048	reviewed	Kinase
P38398	BXGT010037	Breast cancer type 1 susceptibility protein	672	reviewed	Enzyme
P40763	BXGT010202	Signal transducer and activator of transcription 3	6774	reviewed	Nucleic acid binding
P41212	BXGT010235	Transcription factor ETV6	2120	reviewed	Transcription factor
P42224	BXGT010286	Signal transducer and activator of transcription 1-alpha/beta	6772	reviewed	Nucleic acid binding
P42336	BXGT010302	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	5290	reviewed	Kinase
P42338	BXGT010303	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform	5291	reviewed	Kinase
P42357	BXGT010306	Histidine ammonia-lyase	3034	reviewed
P43403	BXGT010385	Tyrosine-protein kinase ZAP-70	7535	reviewed	Kinase
P48023	BXGT010604	Tumor necrosis factor ligand superfamily member 6	356	reviewed	Signaling
P48736	BXGT010658	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	5294	reviewed	Kinase
P49917	BXGT010765	DNA ligase 4	3981	reviewed
P51159	BXGT010839	Ras-related protein Rab-27A	5873	reviewed
P51532	BXGT010852	Transcription activator BRG1	6597	reviewed	Epigenetic regulator
P51617	BXGT010868	Interleukin-1 receptor-associated kinase 1	3654	reviewed	Kinase
P51681	BXGT010878	C-C chemokine receptor type 5	1234	reviewed	G-protein coupled receptor
P51692	BXGT010885	Signal transducer and activator of transcription 5B	6777	reviewed	Nucleic acid binding
P52333	BXGT010928	Tyrosine-protein kinase JAK3	3718	reviewed	Kinase
P60033	BXGT011286	CD81 antigen	975	reviewed
P60568	BXGT011315	Interleukin-2	3558	reviewed
P61073	BXGT011352	C-X-C chemokine receptor type 4	7852	reviewed	G-protein coupled receptor
P61769	BXGT011383	Beta-2-microglobulin	567	reviewed	Immune response
P98170	BXGT012231	E3 ubiquitin-protein ligase XIAP	331	reviewed	Enzyme modulator
Q00653	BXGT012541	Nuclear factor NF-kappa-B p100 subunit	4791	reviewed	Transcription factor
Q01196	BXGT012575	Runt-related transcription factor 1	861	reviewed	Transcription factor
Q03164	BXGT012700	Histone-lysine N-methyltransferase 2A	4297	reviewed
Q04609	BXGT012768	Glutamate carboxypeptidase 2	2346	reviewed	Enzyme
Q05516	BXGT012822	Zinc finger and BTB domain-containing protein 16	7704	reviewed	Transcription factor
Q05655	BXGT012832	Protein kinase C delta type	5580	reviewed	Kinase
Q06187	BXGT012860	Tyrosine-protein kinase BTK	695	reviewed	Kinase
Q07812	BXGT012940	Apoptosis regulator BAX	581	reviewed	Signaling
Q08881	BXGT013012	Tyrosine-protein kinase ITK/TSK	3702	reviewed	Kinase
Q13315	BXGT013339	Serine-protein kinase ATM	472	reviewed	Kinase
Q13426	BXGT013353	DNA repair protein XRCC4	7518	reviewed
Q13485	BXGT013363	Mothers against decapentaplegic homolog 4	4089	reviewed	Transcription factor
Q13546	BXGT013372	Receptor-interacting serine/threonine-protein kinase 1	8737	reviewed	Kinase
Q13586	BXGT013380	Stromal interaction molecule 1	6786	reviewed
Q14145	BXGT013448	Kelch-like ECH-associated protein 1	9817	reviewed
Q14790	BXGT013505	Caspase-8	841	reviewed	Enzyme
Q15139	BXGT013546	Serine/threonine-protein kinase D1	5587	reviewed	Kinase
Q16236	BXGT013624	Nuclear factor erythroid 2-related factor 2	4780	reviewed	Enzyme
Q2M385	BXGT014131	Macrophage-expressed gene 1 protein	219972	reviewed
Q5VWK5	BXGT015891	Interleukin-23 receptor	149233	reviewed	Signaling
Q6N021	BXGT016378	Methylcytosine dioxygenase TET2	54790	reviewed
Q7L266	BXGT016993	Isoaspartyl peptidase/L-asparaginase	80150	reviewed	Enzyme
Q86YC2	BXGT017633	Partner and localizer of BRCA2	79728	reviewed
Q8WXI8	BXGT019014	C-type lectin domain family 4 member D	338339	reviewed
Q96AZ6	BXGT019621	Interferon-stimulated gene 20 kDa protein	3669	reviewed
Q96BN8	BXGT019625	Ubiquitin thioesterase otulin	90268	reviewed
Q96P20	BXGT019704	NACHT, LRR and PYD domains-containing protein 3	114548	reviewed
Q96RJ3	BXGT019729	Tumor necrosis factor receptor superfamily member 13C	115650	reviewed
Q99836	BXGT019970	Myeloid differentiation primary response protein MyD88	4615	reviewed	Enzyme modulator
Q9BXL7	BXGT020171	Caspase recruitment domain-containing protein 11	84433	reviewed
Q9BZS1	BXGT020203	Forkhead box protein P3	50943	reviewed
Q9H0A0	BXGT020434	RNA cytidine acetyltransferase	55226	reviewed
Q9HBE5	BXGT020518	Interleukin-21 receptor	50615	reviewed	Receptor
Q9HC29	BXGT020526	Nucleotide-binding oligomerization domain-containing protein 2	64127	reviewed	Enzyme
Q9NZ08	BXGT021266	Endoplasmic reticulum aminopeptidase 1	51752	reviewed	Enzyme
Q9UM73	BXGT021773	ALK tyrosine kinase receptor	238	reviewed	Kinase
Q9UQF0	BXGT021812	Syncytin-1	30816	reviewed
Q9Y263	BXGT022220	Phospholipase A-2-activating protein	9373	reviewed	Enzyme modulator
Q9Y5X0	BXGT022305	Sorting nexin-10	29887	reviewed
P15260	BXGT023924	Interferon gamma receptor 1	3459	reviewed	Receptor
P07954	BXGT023939	Fumarate hydratase, mitochondrial	2271	reviewed	Enzyme
P29590	BXGT024350	Protein PML	5371	reviewed
Q14980	BXGT025336	Nuclear mitotic apparatus protein 1	4926	reviewed
Q96SD1	BXGT025929	Protein artemis	64421	reviewed
P11836	BXGT025994	B-lymphocyte antigen CD20	931	reviewed	Receptor
P51798	BXGT026083	H(+)/Cl(-) exchange transporter 7	1186	reviewed	Ion channel

The disease-related compounds

Compounds

BXGC Id	Compound Name	Structure	Molecular Weight	Number of targets^{?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease}

The disease-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compounds in food^{?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease}