adisease

Showing entry for Arthralgia

General Disease Information
BXGD Id	BXGD000230
Disease Name	Arthralgia
Disease CUI Id	C0003862
MeSH Codes	C23 C05
Disease Class Name	Pathological Conditions, Signs and Symptoms; Musculoskeletal Diseases
Semantic Type	Sign or Symptom
Human Phenotype Ontology Id	HP:0025142
Human Phenotype Ontology Term	Constitutional symptom
Disease Ontology Id
Disease Ontology Class Name
Disorder Network	disorder-protein-compound-food associations

The disease-related target proteins

Proteins

Uniport Id	BXGT Id	Protein Name	Gene	Status	Protein Class
Uniport Id	BXGT Id	Protein name	Gene	Status	Protein class
F7VJQ1	BXGT003310	Alternative prion protein	5621	reviewed
O00206	BXGT003894	Toll-like receptor 4	7099	reviewed
O15553	BXGT004181	Pyrin	4210	reviewed
O43914	BXGT004635	TYRO protein tyrosine kinase-binding protein	7305	reviewed
O60603	BXGT004887	Toll-like receptor 2	7097	reviewed
O60674	BXGT004892	Tyrosine-protein kinase JAK2	3717	reviewed	Kinase
O75469	BXGT005128	Nuclear receptor subfamily 1 group I member 2	8856	reviewed	Nuclear receptor
O75475	BXGT005130	PC4 and SFRS1-interacting protein	11168	reviewed	Signaling
O76074	BXGT005174	cGMP-specific 3',5'-cyclic phosphodiesterase	8654	reviewed
O95718	BXGT005392	Steroid hormone receptor ERR2	2103	reviewed	Nuclear receptor
P00451	BXGT005545	Coagulation factor VIII	2157	reviewed	Enzyme
P00736	BXGT005632	Complement C1r subcomponent	715	reviewed	Enzyme
P01130	BXGT005735	Low-density lipoprotein receptor	3949	reviewed
P01375	BXGT005753	Tumor necrosis factor	7124	reviewed	Signaling
P01574	BXGT005768	Interferon beta	3456	reviewed
P01583	BXGT005771	Interleukin-1 alpha	3552	reviewed
P01584	BXGT005772	Interleukin-1 beta	3553	reviewed
P01589	BXGT005773	Interleukin-2 receptor subunit alpha	3559	reviewed	Receptor
P01889	BXGT005809	HLA class I histocompatibility antigen, B-7 alpha chain	3106	reviewed
P01909	BXGT005815	HLA class II histocompatibility antigen, DQ alpha 1 chain	3117	reviewed	Immune response
P01911	BXGT005816	HLA class II histocompatibility antigen, DRB1-15 beta chain	3123	reviewed	Immune response
P01920	BXGT005817	HLA class II histocompatibility antigen, DQ beta 1 chain	3119	reviewed	Immune response
P02452	BXGT005878	Collagen alpha-1(I) chain	1277	reviewed
P02458	BXGT005879	Collagen alpha-1(II) chain	1280	reviewed
P02545	BXGT005889	Prelamin-A/C	4000	reviewed
P02741	BXGT005936	C-reactive protein	1401	reviewed
P02792	BXGT005966	Ferritin light chain	2512	reviewed	Storage
P03956	BXGT006120	Interstitial collagenase	4312	reviewed	Enzyme
P04003	BXGT006124	C4b-binding protein alpha chain	722	reviewed
P04035	BXGT006129	3-hydroxy-3-methylglutaryl-coenzyme A reductase	3156	reviewed
P04156	BXGT006156	Major prion protein	5621	reviewed
P04440	BXGT006216	HLA class II histocompatibility antigen, DP beta 1 chain	3115	reviewed	Immune response
P05093	BXGT006313	Steroid 17-alpha-hydroxylase/17,20 lyase	1586	reviewed
P05231	BXGT006345	Interleukin-6	3569	reviewed
P06280	BXGT006433	Alpha-galactosidase A	2717	reviewed
P08183	BXGT006741	ATP-dependent translocase ABCB1	5243	reviewed	Transporter
P08253	BXGT006757	72 kDa type IV collagenase	4313	reviewed	Enzyme
P08254	BXGT006758	Stromelysin-1	4314	reviewed	Enzyme
P08397	BXGT006768	Porphobilinogen deaminase	3145	reviewed	Enzyme
P10145	BXGT007542	Interleukin-8	3576	reviewed	Signaling
P10323	BXGT007557	Acrosin	49	reviewed	Enzyme
P10636	BXGT007596	Microtubule-associated protein tau	4137	reviewed
P11473	BXGT007709	Vitamin D3 receptor	7421	reviewed	Nuclear receptor
P11509	BXGT007716	Cytochrome P450 2A6	1548	reviewed
P11511	BXGT007717	Aromatase	1588	reviewed	Enzyme
P12314	BXGT007798	High affinity immunoglobulin gamma Fc receptor I	2209	reviewed	Cell adhesion
P12643	BXGT007830	Bone morphogenetic protein 2	650	reviewed	Signaling
P12821	BXGT007849	Angiotensin-converting enzyme	1636	reviewed	Enzyme
P14174	BXGT007991	Macrophage migration inhibitory factor	4282	reviewed
P14784	BXGT008054	Interleukin-2 receptor subunit beta	3560	reviewed	Receptor
P15056	BXGT008075	Serine/threonine-protein kinase B-raf	673	reviewed	Kinase
P15085	BXGT008077	Carboxypeptidase A1	1357	reviewed	Enzyme
P15428	BXGT008121	15-hydroxyprostaglandin dehydrogenase [NAD(+)]	3248	reviewed
P15692	BXGT008147	Vascular endothelial growth factor A	7422	reviewed	Signaling
P16410	BXGT008224	Cytotoxic T-lymphocyte protein 4	1493	reviewed
P16442	BXGT008227	Histo-blood group ABO system transferase	28	reviewed	Enzyme
P17706	BXGT008330	Tyrosine-protein phosphatase non-receptor type 2	5771	reviewed
P18074	BXGT008374	General transcription and DNA repair factor IIH helicase subunit XPD	2068	reviewed	Enzyme
P19438	BXGT008480	Tumor necrosis factor receptor superfamily member 1A	7132	reviewed
P19838	BXGT008526	Nuclear factor NF-kappa-B p105 subunit	4790	reviewed	Transcription factor
P20930	BXGT008616	Filaggrin	2312	reviewed	Cellular structure
P22413	BXGT008764	Ectonucleotide pyrophosphatase/phosphodiesterase family member 1	5167	reviewed	Enzyme
P22894	BXGT008815	Neutrophil collagenase	4317	reviewed	Enzyme
P23560	BXGT008883	Brain-derived neurotrophic factor	627	reviewed	Signaling
P24158	BXGT008951	Myeloblastin	5657	reviewed	Enzyme
P25942	BXGT009079	Tumor necrosis factor receptor superfamily member 5	958	reviewed
P27487	BXGT009187	Dipeptidyl peptidase 4	1803	reviewed	Enzyme
P28070	BXGT009230	Proteasome subunit beta type-4	5692	reviewed
P29460	BXGT009348	Interleukin-12 subunit beta	3593	reviewed	Signaling
P29965	BXGT009388	CD40 ligand	959	reviewed	Signaling
P31639	BXGT009556	Sodium/glucose cotransporter 2	6524	reviewed	Transporter
P31645	BXGT009558	Sodium-dependent serotonin transporter	6532	reviewed	Transporter
P32119	BXGT009600	Peroxiredoxin-2	7001	reviewed	Enzyme
P35222	BXGT009799	Catenin beta-1	1499	reviewed
P35270	BXGT009807	Sepiapterin reductase	6697	reviewed
P35354	BXGT009816	Prostaglandin G/H synthase 2	5743	reviewed	Enzyme
P36551	BXGT009927	Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial	1371	reviewed	Enzyme
P41180	BXGT010230	Extracellular calcium-sensing receptor	846	reviewed	G-protein coupled receptor
P49747	BXGT010732	Cartilage oligomeric matrix protein	1311	reviewed
P51580	BXGT010864	Thiopurine S-methyltransferase	7172	reviewed
P51617	BXGT010868	Interleukin-1 receptor-associated kinase 1	3654	reviewed	Kinase
P51684	BXGT010880	C-C chemokine receptor type 6	1235	reviewed	G-protein coupled receptor
P53667	BXGT011008	LIM domain kinase 1	3984	reviewed	Kinase
P55072	BXGT011103	Transitional endoplasmic reticulum ATPase	7415	reviewed
P55085	BXGT011104	Proteinase-activated receptor 2	2150	reviewed	G-protein coupled receptor
P58335	BXGT011233	Anthrax toxin receptor 2	118429	reviewed	Receptor
P60033	BXGT011286	CD81 antigen	975	reviewed
P62258	BXGT011415	14-3-3 protein epsilon	7531	reviewed	Chaperone
P68871	BXGT011615	Hemoglobin subunit beta	3043	reviewed
P80075	BXGT011876	C-C motif chemokine 8	6355	reviewed	Signaling
Q00653	BXGT012541	Nuclear factor NF-kappa-B p100 subunit	4791	reviewed	Transcription factor
Q01831	BXGT012621	DNA repair protein complementing XP-C cells	7508	reviewed	Nucleic acid binding
Q03431	BXGT012714	Parathyroid hormone/parathyroid hormone-related peptide receptor	5745	reviewed	G-protein coupled receptor
Q04721	BXGT012777	Neurogenic locus notch homolog protein 2	4853	reviewed
Q05655	BXGT012832	Protein kinase C delta type	5580	reviewed	Kinase
Q07954	BXGT012950	Prolow-density lipoprotein receptor-related protein 1	4035	reviewed
Q13510	BXGT013367	Acid ceramidase	427	reviewed	Enzyme
Q15116	BXGT013539	Programmed cell death protein 1	5133	reviewed
Q30201	BXGT014297	Hereditary hemochromatosis protein	3077	reviewed
Q5VWK5	BXGT015891	Interleukin-23 receptor	149233	reviewed	Signaling
Q5Y7D3	BXGT015912	HLA class II histocompatibility antigen DQ beta chain	3119	unreviewed
Q6N021	BXGT016378	Methylcytosine dioxygenase TET2	54790	reviewed
Q8NBP7	BXGT018541	Proprotein convertase subtilisin/kexin type 9	255738	reviewed	Enzyme
Q8WZ42	BXGT019023	Titin	7273	reviewed	Kinase
Q92959	BXGT019400	Solute carrier organic anion transporter family member 2A1	6578	reviewed	Transporter
Q96BN8	BXGT019625	Ubiquitin thioesterase otulin	90268	reviewed
Q96P20	BXGT019704	NACHT, LRR and PYD domains-containing protein 3	114548	reviewed
Q96RJ3	BXGT019729	Tumor necrosis factor receptor superfamily member 13C	115650	reviewed
Q99572	BXGT019935	P2X purinoceptor 7	5027	reviewed	Ion channel
Q99700	BXGT019949	Ataxin-2	6311	reviewed	Nucleic acid binding
Q9BUF5	BXGT020135	Tubulin beta-6 chain	84617	reviewed	Cellular structure
Q9BY32	BXGT020179	Inosine triphosphate pyrophosphatase	3704	reviewed	Enzyme
Q9HBA0	BXGT020516	Transient receptor potential cation channel subfamily V member 4	59341	reviewed	Ion channel
Q9HC29	BXGT020526	Nucleotide-binding oligomerization domain-containing protein 2	64127	reviewed	Enzyme
Q9NP58	BXGT021143	ATP-binding cassette sub-family B member 6, mitochondrial	10058	reviewed	Transporter
Q9NZ08	BXGT021266	Endoplasmic reticulum aminopeptidase 1	51752	reviewed	Enzyme
Q9NZQ7	BXGT021281	Programmed cell death 1 ligand 1	29126	reviewed	Receptor
Q9UHD8	BXGT021698	Septin-9	10801	reviewed	Enzyme modulator
Q9UKU7	BXGT021749	Isobutyryl-CoA dehydrogenase, mitochondrial	27034	reviewed	Enzyme
Q9UM07	BXGT021771	Protein-arginine deiminase type-4	23569	reviewed
Q9Y2R2	BXGT022243	Tyrosine-protein phosphatase non-receptor type 22	26191	reviewed
P20036	BXGT022764	HLA class II histocompatibility antigen, DP alpha 1 chain	3113	reviewed	Immune response
P19235	BXGT022895	Erythropoietin receptor	2057	reviewed	Receptor
P25054	BXGT022961	Adenomatous polyposis coli protein	324	reviewed
P35670	BXGT023695	Copper-transporting ATPase 2	540	reviewed	Transporter
O95140	BXGT024482	Mitofusin-2	9927	reviewed	Enzyme
Q9Y4W6	BXGT025025	AFG3-like protein 2	10939	reviewed	Enzyme
P51608	BXGT025073	Methyl-CpG-binding protein 2	4204	reviewed	Epigenetic regulator
P53621	BXGT025196	Coatomer subunit alpha	1314	reviewed	Transporter
P28715	BXGT025675	DNA repair protein complementing XP-G cells	2073	reviewed
P35250	BXGT025854	Replication factor C subunit 2	5982	reviewed	Enzyme
Q96RD7	BXGT025890	Pannexin-1	24145	reviewed	Ion channel
P11836	BXGT025994	B-lymphocyte antigen CD20	931	reviewed	Receptor
P00403	BXGT026137	Cytochrome c oxidase subunit 2	4513	reviewed	Enzyme

The disease-related compounds

Compounds

BXGC Id	Compound Name	Structure	Molecular Weight	Number of targets^{?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease}

The disease-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compounds in food^{?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease}