adisease

Showing entry for Meningitis

General Disease Information
BXGD Id	BXGD001851
Disease Name	Meningitis
Disease CUI Id	C0025289
MeSH Codes	C10
Disease Class Name	Nervous System Diseases
Semantic Type	Disease or Syndrome
Human Phenotype Ontology Id	HP:0000707 HP:0002715
Human Phenotype Ontology Term	Abnormality of the nervous system; Abnormality of the immune system
Disease Ontology Id	DOID:7
Disease Ontology Class Name	disease of anatomical entity
Disorder Network	disorder-protein-compound-food associations

The disease-related target proteins

Proteins

Uniport Id	BXGT Id	Protein Name	Gene	Status	Protein Class
Uniport Id	BXGT Id	Protein name	Gene	Status	Protein class
F7VJQ1	BXGT003310	Alternative prion protein	5621	reviewed
O00206	BXGT003894	Toll-like receptor 4	7099	reviewed
O15455	BXGT004171	Toll-like receptor 3	7098	reviewed	Receptor
O15527	BXGT004176	N-glycosylase/DNA lyase	4968	reviewed
O15553	BXGT004181	Pyrin	4210	reviewed
O43353	BXGT004589	Receptor-interacting serine/threonine-protein kinase 2	8767	reviewed	Kinase
O60603	BXGT004887	Toll-like receptor 2	7097	reviewed
O60741	BXGT004897	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1	348980	reviewed
P00533	BXGT005575	Epidermal growth factor receptor	1956	reviewed	Kinase
P01133	BXGT005736	Pro-epidermal growth factor	1950	reviewed
P01137	BXGT005737	Transforming growth factor beta-1 proprotein	7040	reviewed	Signaling
P01375	BXGT005753	Tumor necrosis factor	7124	reviewed	Signaling
P01579	BXGT005770	Interferon gamma	3458	reviewed
P01584	BXGT005772	Interleukin-1 beta	3553	reviewed
P01889	BXGT005809	HLA class I histocompatibility antigen, B-7 alpha chain	3106	reviewed
P01911	BXGT005816	HLA class II histocompatibility antigen, DRB1-15 beta chain	3123	reviewed	Immune response
P02741	BXGT005936	C-reactive protein	1401	reviewed
P02750	BXGT005942	Leucine-rich alpha-2-glycoprotein	116844	reviewed
P02751	BXGT005943	Fibronectin	2335	reviewed	Signaling
P02760	BXGT005948	Protein AMBP	259	reviewed
P02774	BXGT005959	Vitamin D-binding protein	2638	reviewed	Transporter
P03372	BXGT006059	Estrogen receptor	2099	reviewed	Nuclear receptor
P04003	BXGT006124	C4b-binding protein alpha chain	722	reviewed
P04040	BXGT006132	Catalase	847	reviewed	Enzyme
P04156	BXGT006156	Major prion protein	5621	reviewed
P04440	BXGT006216	HLA class II histocompatibility antigen, DP beta 1 chain	3115	reviewed	Immune response
P04626	BXGT006238	Receptor tyrosine-protein kinase erbB-2	2064	reviewed	Kinase
P04839	BXGT006273	Cytochrome b-245 heavy chain	1536	reviewed	Ion channel
P05121	BXGT006320	Plasminogen activator inhibitor 1	5054	reviewed	Enzyme modulator
P05164	BXGT006333	Myeloperoxidase	4353	reviewed	Enzyme
P05231	BXGT006345	Interleukin-6	3569	reviewed
P05362	BXGT006350	Intercellular adhesion molecule 1	3383	reviewed
P07288	BXGT006591	Prostate-specific antigen	354	reviewed	Enzyme
P07357	BXGT006610	Complement component C8 alpha chain	731	reviewed
P07358	BXGT006611	Complement component C8 beta chain	732	reviewed
P07741	BXGT006666	Adenine phosphoribosyltransferase	353	reviewed
P07996	BXGT006710	Thrombospondin-1	7057	reviewed
P08254	BXGT006758	Stromelysin-1	4314	reviewed	Enzyme
P08603	BXGT006798	Complement factor H	3075	reviewed
P08637	BXGT006802	Low affinity immunoglobulin gamma Fc region receptor III-A	2214	reviewed	Cell adhesion
P08670	BXGT006810	Vimentin	7431	reviewed
P09874	BXGT006934	Poly [ADP-ribose] polymerase 1	142	reviewed
P0C0L4	BXGT007387	Complement C4-A	721	reviewed
P0C0L5	BXGT007388	Complement C4-B	721	reviewed
P10145	BXGT007542	Interleukin-8	3576	reviewed	Signaling
P10147	BXGT007543	C-C motif chemokine 3	6348	reviewed	Signaling
P10415	BXGT007567	Apoptosis regulator Bcl-2	596	reviewed	Signaling
P10636	BXGT007596	Microtubule-associated protein tau	4137	reviewed
P11226	BXGT007675	Mannose-binding protein C	4153	reviewed	Receptor
P11912	BXGT007758	B-cell antigen receptor complex-associated protein alpha chain	973	reviewed	Receptor
P12314	BXGT007798	High affinity immunoglobulin gamma Fc receptor I	2209	reviewed	Cell adhesion
P12318	BXGT007799	Low affinity immunoglobulin gamma Fc region receptor II-a	2212	reviewed	Cell adhesion
P14598	BXGT008024	Neutrophil cytosol factor 1	653361	reviewed
P14625	BXGT008029	Endoplasmin	7184	reviewed	Chaperone
P14780	BXGT008053	Matrix metalloproteinase-9	4318	reviewed	Enzyme
P15814	BXGT008159	Immunoglobulin lambda-like polypeptide 1	3543	reviewed
P16410	BXGT008224	Cytotoxic T-lymphocyte protein 4	1493	reviewed
P19883	BXGT008528	Follistatin	10468	reviewed	Enzyme modulator
P22894	BXGT008815	Neutrophil collagenase	4317	reviewed	Enzyme
P23560	BXGT008883	Brain-derived neurotrophic factor	627	reviewed	Signaling
P24158	BXGT008951	Myeloblastin	5657	reviewed	Enzyme
P27986	BXGT009216	Phosphatidylinositol 3-kinase regulatory subunit alpha	5295	reviewed	Kinase
P29474	BXGT009352	Nitric oxide synthase, endothelial	4846	reviewed
P31785	BXGT009577	Cytokine receptor common subunit gamma	3561	reviewed	Signaling
P32119	BXGT009600	Peroxiredoxin-2	7001	reviewed	Enzyme
P34059	BXGT009749	N-acetylgalactosamine-6-sulfatase	2588	reviewed	Enzyme
P36222	BXGT009914	Chitinase-3-like protein 1	1116	reviewed
P39900	BXGT010148	Macrophage metalloelastase	4321	reviewed	Enzyme
P40763	BXGT010202	Signal transducer and activator of transcription 3	6774	reviewed	Nucleic acid binding
P41182	BXGT010231	B-cell lymphoma 6 protein	604	reviewed
P49913	BXGT010761	Cathelicidin antimicrobial peptide	820	reviewed
P50591	BXGT010814	Tumor necrosis factor ligand superfamily member 10	8743	reviewed	Signaling
P52333	BXGT010928	Tyrosine-protein kinase JAK3	3718	reviewed	Kinase
P55087	BXGT011105	Aquaporin-4	361	reviewed	Ion channel
P61073	BXGT011352	C-X-C chemokine receptor type 4	7852	reviewed	G-protein coupled receptor
P61626	BXGT011382	Lysozyme C	4069	reviewed
P80075	BXGT011876	C-C motif chemokine 8	6355	reviewed	Signaling
P98170	BXGT012231	E3 ubiquitin-protein ligase XIAP	331	reviewed	Enzyme modulator
Q06187	BXGT012860	Tyrosine-protein kinase BTK	695	reviewed	Kinase
Q08722	BXGT013002	Leukocyte surface antigen CD47	961	reviewed
Q13946	BXGT013406	High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A	5150	reviewed
Q14116	BXGT013442	Interleukin-18	3606	reviewed
Q15080	BXGT013535	Neutrophil cytosol factor 4	4689	reviewed
Q5VWK5	BXGT015891	Interleukin-23 receptor	149233	reviewed	Signaling
Q7L5Y1	BXGT016996	Mitochondrial enolase superfamily member 1	55556	reviewed	Enzyme
Q8N5Z0	BXGT018521	Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial	51166	reviewed	Enzyme
Q8NBJ7	BXGT018537	Inactive C-alpha-formylglycine-generating enzyme 2	25870	reviewed
Q96P20	BXGT019704	NACHT, LRR and PYD domains-containing protein 3	114548	reviewed
Q96RJ3	BXGT019729	Tumor necrosis factor receptor superfamily member 13C	115650	reviewed
Q99519	BXGT019928	Sialidase-1	4758	reviewed	Enzyme
Q99836	BXGT019970	Myeloid differentiation primary response protein MyD88	4615	reviewed	Enzyme modulator
Q99873	BXGT019972	Protein arginine N-methyltransferase 1	3276	reviewed	Epigenetic regulator
Q9BZS1	BXGT020203	Forkhead box protein P3	50943	reviewed
Q9HC29	BXGT020526	Nucleotide-binding oligomerization domain-containing protein 2	64127	reviewed	Enzyme
Q9NP58	BXGT021143	ATP-binding cassette sub-family B member 6, mitochondrial	10058	reviewed	Transporter
Q9NR96	BXGT021181	Toll-like receptor 9	54106	reviewed
Q9NWZ3	BXGT021239	Interleukin-1 receptor-associated kinase 4	51135	reviewed	Kinase
Q9NZ08	BXGT021266	Endoplasmic reticulum aminopeptidase 1	51752	reviewed	Enzyme
Q9UEW3	BXGT021674	Macrophage receptor MARCO	8685	reviewed
Q9UHD2	BXGT021697	Serine/threonine-protein kinase TBK1	29110	reviewed	Kinase
Q9UL51	BXGT021754	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2	610	reviewed	Ion channel
Q9Y2R2	BXGT022243	Tyrosine-protein phosphatase non-receptor type 22	26191	reviewed
P04439	BXGT022649	HLA class I histocompatibility antigen, A-3 alpha chain	3105	reviewed
P20036	BXGT022764	HLA class II histocompatibility antigen, DP alpha 1 chain	3113	reviewed	Immune response
Q16552	BXGT023419	Interleukin-17A	3605	reviewed
P51608	BXGT025073	Methyl-CpG-binding protein 2	4204	reviewed	Epigenetic regulator

The disease-related compounds

Compounds

BXGC Id	Compound Name	Structure	Molecular Weight	Number of targets^{?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease}

The disease-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compounds in food^{?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease}