Showing entry for Hepatosplenomegaly


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Disease Information
BXGD IdBXGD001307
Disease NameHepatosplenomegaly
Disease CUI IdC0019214
MeSH Codes C23   C06   C15  
Disease Class NamePathological Conditions, Signs and Symptoms; Digestive System Diseases; Hemic and Lymphatic Diseases
Semantic TypeSign or Symptom
Human Phenotype Ontology Id HP:0025031   HP:0002715   HP:0001626  
Human Phenotype Ontology TermAbnormality of the digestive system; Abnormality of the immune system; Abnormality of the cardiovascular system
Disease Ontology Id   
Disease Ontology Class Name
Disorder Network disorder-protein-compound-food associations
The  disease-related  target proteins
Proteins
Uniport Id BXGT Id Protein Name Gene Status Protein Class
Uniport Id BXGT Id Protein name Gene Status Protein class
A0A024RAV5 BXGT000013 V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog, isoform CRA_b 3845 unreviewed
O00329 BXGT003909 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform 5293 reviewed Kinase
O14788 BXGT004100 Tumor necrosis factor ligand superfamily member 11 8600 reviewed Signaling
O15118 BXGT004127 NPC intracellular cholesterol transporter 1 4864 reviewed Transporter
O60674 BXGT004892 Tyrosine-protein kinase JAK2 3717 reviewed Kinase
O95477 BXGT005383 Phospholipid-transporting ATPase ABCA1 19 reviewed Transporter
P00519 BXGT005570 Tyrosine-protein kinase ABL1 25 reviewed Kinase
P00734 BXGT005630 Prothrombin 2147 reviewed Enzyme
P00918 BXGT005690 Carbonic anhydrase 2 760 reviewed
P01116 BXGT005733 GTPase KRas 3845 reviewed Enzyme modulator
P01137 BXGT005737 Transforming growth factor beta-1 proprotein 7040 reviewed Signaling
P01589 BXGT005773 Interleukin-2 receptor subunit alpha 3559 reviewed Receptor
P02730 BXGT005935 Band 3 anion transport protein 6521 reviewed Transporter
P04062 BXGT006140 Lysosomal acid glucosylceramidase 2629 reviewed
P04271 BXGT006177 Protein S100-B 6285 reviewed Calcium-binding protein
P04275 BXGT006180 von Willebrand factor 7450 reviewed Enzyme modulator
P04637 BXGT006243 Cellular tumor antigen p53 7157 reviewed Transcription factor
P05231 BXGT006345 Interleukin-6 3569 reviewed
P06748 BXGT006497 Nucleophosmin 4869 reviewed Chaperone
P06858 BXGT006515 Lipoprotein lipase 4023 reviewed Enzyme
P07602 BXGT006646 Prosaposin 5660 reviewed
P07686 BXGT006657 Beta-hexosaminidase subunit beta 3074 reviewed Enzyme
P08253 BXGT006757 72 kDa type IV collagenase 4313 reviewed Enzyme
P10721 BXGT007605 Mast/stem cell growth factor receptor Kit 3815 reviewed Kinase
P11166 BXGT007661 Solute carrier family 2, facilitated glucose transporter member 1 6513 reviewed Transporter
P15884 BXGT008166 Transcription factor 4 6925 reviewed Transcription factor
P16278 BXGT008213 Beta-galactosidase 2720 reviewed Enzyme
P16871 BXGT008269 Interleukin-7 receptor subunit alpha 3575 reviewed Receptor
P17405 BXGT008304 Sphingomyelin phosphodiesterase 6609 reviewed Enzyme
P21802 BXGT008691 Fibroblast growth factor receptor 2 2263 reviewed Kinase
P23297 BXGT008848 Protein S100-A1 6271 reviewed Calcium-binding protein
P24941 BXGT009002 Cyclin-dependent kinase 2 1017 reviewed Kinase
P27797 BXGT009206 Calreticulin 811 reviewed Calcium-binding protein
P29965 BXGT009388 CD40 ligand 959 reviewed Signaling
P35475 BXGT009837 Alpha-L-iduronidase 3425 reviewed Enzyme
P36888 BXGT009938 Receptor-type tyrosine-protein kinase FLT3 2322 reviewed Kinase
P38398 BXGT010037 Breast cancer type 1 susceptibility protein 672 reviewed Enzyme
P38571 BXGT010054 Lysosomal acid lipase/cholesteryl ester hydrolase 3988 reviewed Enzyme
P42224 BXGT010286 Signal transducer and activator of transcription 1-alpha/beta 6772 reviewed Nucleic acid binding
P43403 BXGT010385 Tyrosine-protein kinase ZAP-70 7535 reviewed Kinase
P48506 BXGT010635 Glutamate--cysteine ligase catalytic subunit 2729 reviewed Enzyme
P51688 BXGT010883 N-sulphoglucosamine sulphohydrolase 6448 reviewed Enzyme
P52333 BXGT010928 Tyrosine-protein kinase JAK3 3718 reviewed Kinase
P54802 BXGT011081 Alpha-N-acetylglucosaminidase 4669 reviewed
P55265 BXGT011117 Double-stranded RNA-specific adenosine deaminase 103 reviewed Enzyme
P68871 BXGT011615 Hemoglobin subunit beta 3043 reviewed
P69905 BXGT011649 Hemoglobin subunit alpha 3040 reviewed
P98170 BXGT012231 E3 ubiquitin-protein ligase XIAP 331 reviewed Enzyme modulator
Q01196 BXGT012575 Runt-related transcription factor 1 861 reviewed Transcription factor
Q04446 BXGT012764 1,4-alpha-glucan-branching enzyme 2632 reviewed Enzyme
Q13231 BXGT013329 Chitotriosidase-1 1118 reviewed
Q13485 BXGT013363 Mothers against decapentaplegic homolog 4 4089 reviewed Transcription factor
Q15833 BXGT013605 Syntaxin-binding protein 2 6813 reviewed Transporter
Q658P3 BXGT016142 Metalloreductase STEAP3 55240 reviewed
Q6N021 BXGT016378 Methylcytosine dioxygenase TET2 54790 reviewed
Q86SX6 BXGT017601 Glutaredoxin-related protein 5, mitochondrial 51218 reviewed Enzyme
Q86YC2 BXGT017633 Partner and localizer of BRCA2 79728 reviewed
Q8TDQ0 BXGT018810 Hepatitis A virus cellular receptor 2 84868 reviewed
Q96J02 BXGT019679 E3 ubiquitin-protein ligase Itchy homolog 83737 reviewed Enzyme
Q9H8P0 BXGT020497 Polyprenol reductase 79644 reviewed
Q9HC97 BXGT020527 G-protein coupled receptor 35 2859 reviewed G-protein coupled receptor
Q9UJS0 BXGT021727 Calcium-binding mitochondrial carrier protein Aralar2 10165 reviewed Transporter
Q9UKU7 BXGT021749 Isobutyryl-CoA dehydrogenase, mitochondrial 27034 reviewed Enzyme
Q9UM73 BXGT021773 ALK tyrosine kinase receptor 238 reviewed Kinase
Q9Y223 BXGT022207 Bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase 10020 reviewed Enzyme
Q9Y3Z3 BXGT022268 Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 25939 reviewed
P07766 BXGT023327 T-cell surface glycoprotein CD3 epsilon chain 916 reviewed
P15260 BXGT023924 Interferon gamma receptor 1 3459 reviewed Receptor
P61916 BXGT025881 NPC intracellular cholesterol transporter 2 10577 reviewed
P11836 BXGT025994 B-lymphocyte antigen CD20 931 reviewed Receptor
P51798 BXGT026083 H(+)/Cl(-) exchange transporter 7 1186 reviewed Ion channel
The  disease-related  compounds
Compounds
BXGC Id Compound Name Structure Molecular Weight Number of targets?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease
The  disease-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compounds in food?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease