Showing entry for Dissection of aorta


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Disease Information
BXGD IdBXGD007357
Disease NameDissection of aorta
Disease CUI IdC0340643
MeSH Codes C14  
Disease Class NameCardiovascular Diseases
Semantic TypeDisease or Syndrome
Human Phenotype Ontology Id HP:0001626  
Human Phenotype Ontology TermAbnormality of the cardiovascular system
Disease Ontology Id   
Disease Ontology Class Name
Disorder Network disorder-protein-compound-food associations
The  disease-related  target proteins
Proteins
Uniport Id BXGT Id Protein Name Gene Status Protein Class
Uniport Id BXGT Id Protein name Gene Status Protein class
O14733 BXGT004087 Dual specificity mitogen-activated protein kinase kinase 7 5609 reviewed Kinase
O15123 BXGT004130 Angiopoietin-2 285 reviewed Signaling
O95835 BXGT005400 Serine/threonine-protein kinase LATS1 9113 reviewed Kinase
P00441 BXGT005540 Superoxide dismutase [Cu-Zn] 6647 reviewed Enzyme
P01009 BXGT005714 Alpha-1-antitrypsin 5265 reviewed Enzyme modulator
P01019 BXGT005717 Angiotensinogen 183 reviewed Enzyme modulator
P01130 BXGT005735 Low-density lipoprotein receptor 3949 reviewed
P01375 BXGT005753 Tumor necrosis factor 7124 reviewed Signaling
P01579 BXGT005770 Interferon gamma 3458 reviewed
P01584 BXGT005772 Interleukin-1 beta 3553 reviewed
P02452 BXGT005878 Collagen alpha-1(I) chain 1277 reviewed
P02461 BXGT005880 Collagen alpha-1(III) chain 1281 reviewed
P02649 BXGT005909 Apolipoprotein E 348 reviewed
P02741 BXGT005936 C-reactive protein 1401 reviewed
P03886 BXGT006108 NADH-ubiquinone oxidoreductase chain 1 4535 reviewed Enzyme
P03905 BXGT006113 NADH-ubiquinone oxidoreductase chain 4 4538 reviewed Enzyme
P03915 BXGT006114 NADH-ubiquinone oxidoreductase chain 5 4540 reviewed Enzyme
P03923 BXGT006115 NADH-ubiquinone oxidoreductase chain 6 4541 reviewed
P04278 BXGT006182 Sex hormone-binding globulin 6462 reviewed
P05231 BXGT006345 Interleukin-6 3569 reviewed
P07900 BXGT006696 Heat shock protein HSP 90-alpha 3320 reviewed Chaperone
P07996 BXGT006710 Thrombospondin-1 7057 reviewed
P08253 BXGT006757 72 kDa type IV collagenase 4313 reviewed Enzyme
P08254 BXGT006758 Stromelysin-1 4314 reviewed Enzyme
P12821 BXGT007849 Angiotensin-converting enzyme 1636 reviewed Enzyme
P13500 BXGT007916 C-C motif chemokine 2 6347 reviewed Signaling
P14780 BXGT008053 Matrix metalloproteinase-9 4318 reviewed Enzyme
P16581 BXGT008245 E-selectin 6401 reviewed
P17516 BXGT008313 Aldo-keto reductase family 1 member C4 1109 reviewed Enzyme
P19429 BXGT008479 Troponin I, cardiac muscle 7137 reviewed Cellular structure
P22894 BXGT008815 Neutrophil collagenase 4317 reviewed Enzyme
P27352 BXGT009174 Cobalamin binding intrinsic factor 2694 reviewed
P27361 BXGT009176 Mitogen-activated protein kinase 3 5595 reviewed Kinase
P27797 BXGT009206 Calreticulin 811 reviewed Calcium-binding protein
P28300 BXGT009243 Protein-lysine 6-oxidase 4015 reviewed
P35408 BXGT009828 Prostaglandin E2 receptor EP4 subtype 5734 reviewed G-protein coupled receptor
P35555 BXGT009845 Fibrillin-1 2200 reviewed Calcium-binding protein
P36897 BXGT009941 TGF-beta receptor type-1 7046 reviewed Kinase
P37173 BXGT009970 TGF-beta receptor type-2 7048 reviewed Kinase
P39900 BXGT010148 Macrophage metalloelastase 4321 reviewed Enzyme
P40189 BXGT010164 Interleukin-6 receptor subunit beta 3572 reviewed Signaling
P40763 BXGT010202 Signal transducer and activator of transcription 3 6774 reviewed Nucleic acid binding
P41597 BXGT010268 C-C chemokine receptor type 2 729230 reviewed
P42224 BXGT010286 Signal transducer and activator of transcription 1-alpha/beta 6772 reviewed Nucleic acid binding
P42574 BXGT010317 Caspase-3 836 reviewed Enzyme
P46937 BXGT010554 Transcriptional coactivator YAP1 10413 reviewed Enzyme modulator
P48506 BXGT010635 Glutamate--cysteine ligase catalytic subunit 2729 reviewed Enzyme
P50281 BXGT010788 Matrix metalloproteinase-14 4323 reviewed Enzyme
P51149 BXGT010835 Ras-related protein Rab-7a 7879 reviewed
P51532 BXGT010852 Transcription activator BRG1 6597 reviewed Epigenetic regulator
P55042 BXGT011100 GTP-binding protein RAD 6236 reviewed
P58004 BXGT011222 Sestrin-2 83667 reviewed Enzyme
P60709 BXGT011322 Actin, cytoplasmic 1 60 reviewed Cellular structure
P62736 BXGT011452 Actin, aortic smooth muscle 59 reviewed Cellular structure
P84022 BXGT012027 Mothers against decapentaplegic homolog 3 4088 reviewed Transcription factor
Q00987 BXGT012559 E3 ubiquitin-protein ligase Mdm2 4193 reviewed Nucleic acid binding
Q02809 BXGT012674 Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1 5351 reviewed Enzyme
Q13043 BXGT013307 Serine/threonine-protein kinase 4 6789 reviewed Kinase
Q13485 BXGT013363 Mothers against decapentaplegic homolog 4 4089 reviewed Transcription factor
Q13563 BXGT013377 Polycystin-2 5311 reviewed Ion channel
Q13976 BXGT013409 cGMP-dependent protein kinase 1 5592 reviewed Kinase
Q14116 BXGT013442 Interleukin-18 3606 reviewed
Q15746 BXGT013591 Myosin light chain kinase, smooth muscle 4638 reviewed Kinase
Q15796 BXGT013599 Mothers against decapentaplegic homolog 2 4087 reviewed Transcription factor
Q15910 BXGT013612 Histone-lysine N-methyltransferase EZH2 2146 reviewed Epigenetic regulator
Q16236 BXGT013624 Nuclear factor erythroid 2-related factor 2 4780 reviewed Enzyme
Q16665 BXGT013653 Hypoxia-inducible factor 1-alpha 3091 reviewed Transcription factor
Q8NBP7 BXGT018541 Proprotein convertase subtilisin/kexin type 9 255738 reviewed Enzyme
Q8NCC3 BXGT018546 Group XV phospholipase A2 23659 reviewed Enzyme
Q96P20 BXGT019704 NACHT, LRR and PYD domains-containing protein 3 114548 reviewed
Q9BQB6 BXGT020108 Vitamin K epoxide reductase complex subunit 1 79001 reviewed Enzyme
Q9BYF1 BXGT020186 Angiotensin-converting enzyme 2 59272 reviewed Enzyme
Q9GZX6 BXGT020428 Interleukin-22 50616 reviewed
Q9NR19 BXGT021175 Acetyl-coenzyme A synthetase, cytoplasmic 55902 reviewed Enzyme
Q9UBN7 BXGT021658 Histone deacetylase 6 10013 reviewed Epigenetic regulator
Q9Y2R2 BXGT022243 Tyrosine-protein phosphatase non-receptor type 22 26191 reviewed
Q9Y4P1 BXGT022283 Cysteine protease ATG4B 23192 reviewed Enzyme
Q01995 BXGT022678 Transgelin 6876 reviewed Cellular structure
P16284 BXGT022972 Platelet endothelial cell adhesion molecule 5175 reviewed Cell adhesion
O14793 BXGT023280 Growth/differentiation factor 8 2660 reviewed Signaling
Q16552 BXGT023419 Interleukin-17A 3605 reviewed
P00395 BXGT023596 Cytochrome c oxidase subunit 1 4512 reviewed Enzyme
Q14258 BXGT024016 E3 ubiquitin/ISG15 ligase TRIM25 7706 reviewed
O95140 BXGT024482 Mitofusin-2 9927 reviewed Enzyme
P20809 BXGT025043 Interleukin-11 3589 reviewed
Q8NI99 BXGT025986 Angiopoietin-related protein 6 83854 reviewed Signaling
P00403 BXGT026137 Cytochrome c oxidase subunit 2 4513 reviewed Enzyme
The  disease-related  compounds
Compounds
BXGC Id Compound Name Structure Molecular Weight Number of targets?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease
The  disease-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compounds in food?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease