adisease

Showing entry for Motor retardation

General Disease Information
BXGD Id	BXGD008522
Disease Name	Motor retardation
Disease CUI Id	C0424230
MeSH Codes	C23 C10 F01
Disease Class Name	Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Behavior and Behavior Mechanisms
Semantic Type	Finding
Human Phenotype Ontology Id	HP:0000707
Human Phenotype Ontology Term	Abnormality of the nervous system
Disease Ontology Id
Disease Ontology Class Name
Disorder Network	disorder-protein-compound-food associations

The disease-related target proteins

Proteins

Uniport Id	BXGT Id	Protein Name	Gene	Status	Protein Class
Uniport Id	BXGT Id	Protein name	Gene	Status	Protein class
O14770	BXGT004095	Homeobox protein Meis2	4212	reviewed	Enzyme
O15305	BXGT004152	Phosphomannomutase 2	5373	reviewed	Enzyme
O95831	BXGT005399	Apoptosis-inducing factor 1, mitochondrial	9131	reviewed	Enzyme
P04062	BXGT006140	Lysosomal acid glucosylceramidase	2629	reviewed
P05165	BXGT006334	Propionyl-CoA carboxylase alpha chain, mitochondrial	5095	reviewed	Enzyme
P05166	BXGT006335	Propionyl-CoA carboxylase beta chain, mitochondrial	5096	reviewed	Enzyme
P06850	BXGT006511	Corticoliberin	1392	reviewed	Signaling
P08559	BXGT006788	Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial	5160	reviewed
P09417	BXGT006888	Dihydropteridine reductase	5860	reviewed	Enzyme
P11362	BXGT007693	Fibroblast growth factor receptor 1	2260	reviewed	Kinase
P11498	BXGT007714	Pyruvate carboxylase, mitochondrial	5091	reviewed	Enzyme
P14867	BXGT008061	Gamma-aminobutyric acid receptor subunit alpha-1	2554	reviewed	Ion channel
P15328	BXGT008108	Folate receptor alpha	2348	reviewed
P17405	BXGT008304	Sphingomyelin phosphodiesterase	6609	reviewed	Enzyme
P18074	BXGT008374	General transcription and DNA repair factor IIH helicase subunit XPD	2068	reviewed	Enzyme
P18507	BXGT008411	Gamma-aminobutyric acid receptor subunit gamma-2	2566	reviewed	Ion channel
P21796	BXGT008690	Voltage-dependent anion-selective channel protein 1	7416	reviewed
P30793	BXGT009466	GTP cyclohydrolase 1	2643	reviewed	Enzyme
P31040	BXGT009503	Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial	6389	reviewed	Enzyme
P35498	BXGT009838	Sodium channel protein type 1 subunit alpha	6323	reviewed	Ion channel
P51649	BXGT010872	Succinate-semialdehyde dehydrogenase, mitochondrial	7915	reviewed	Enzyme
P51812	BXGT010893	Ribosomal protein S6 kinase alpha-3	6197	reviewed	Kinase
P54886	BXGT011092	Delta-1-pyrroline-5-carboxylate synthase	5832	reviewed	Enzyme
P80404	BXGT011907	4-aminobutyrate aminotransferase, mitochondrial	18	reviewed	Enzyme
P98155	BXGT012226	Very low-density lipoprotein receptor	7436	reviewed
Q03154	BXGT012698	Aminoacylase-1	95	reviewed
Q03393	BXGT012711	6-pyruvoyl tetrahydrobiopterin synthase	5805	reviewed
Q03468	BXGT012716	DNA excision repair protein ERCC-6	2074	reviewed
Q15858	BXGT013610	Sodium channel protein type 9 subunit alpha	6335	reviewed	Ion channel
Q16719	BXGT013662	Kynureninase	8942	reviewed	Enzyme
Q8TC12	BXGT018793	Retinol dehydrogenase 11	51109	reviewed	Enzyme
Q96EQ8	BXGT019652	E3 ubiquitin-protein ligase RNF125	54941	reviewed
Q96RQ3	BXGT019732	Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial	56922	reviewed	Enzyme
Q99250	BXGT019913	Sodium channel protein type 2 subunit alpha	6326	reviewed	Ion channel
Q99986	BXGT019980	Serine/threonine-protein kinase VRK1	7443	reviewed	Kinase
Q9HCC0	BXGT020530	Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial	64087	reviewed	Enzyme
Q9UKM7	BXGT021747	Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase	11253	reviewed	Chaperone
Q9Y617	BXGT022314	Phosphoserine aminotransferase	29968	reviewed
Q9Y619	BXGT022316	Mitochondrial ornithine transporter 1	10166	reviewed	Transporter
Q59FF6	BXGT023693	Excision repair cross-complementing rodent repair deficiency, complementation group 6 variant	2074	unreviewed
P51608	BXGT025073	Methyl-CpG-binding protein 2	4204	reviewed	Epigenetic regulator
Q8TAB3	BXGT025819	Protocadherin-19	57526	reviewed

The disease-related compounds

Compounds

BXGC Id	Compound Name	Structure	Molecular Weight	Number of targets^{?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease}

The disease-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compounds in food^{?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease}