Showing entry for Flexion contracture


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Disease Information
BXGD IdBXGD006920
Disease NameFlexion contracture
Disease CUI IdC0333068
MeSH Codes C05  
Disease Class NameMusculoskeletal Diseases
Semantic TypeFinding
Human Phenotype Ontology Id HP:0000924   HP:0003549   HP:0003011  
Human Phenotype Ontology TermAbnormality of the skeletal system; Abnormality of connective tissue; Abnormality of the musculature
Disease Ontology Id   
Disease Ontology Class Name
Disorder Network disorder-protein-compound-food associations
The  disease-related  target proteins
Proteins
Uniport Id BXGT Id Protein Name Gene Status Protein Class
Uniport Id BXGT Id Protein name Gene Status Protein class
A0A024RAV5 BXGT000013 V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog, isoform CRA_b 3845 unreviewed
O00469 BXGT003926 Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2 5352 reviewed Enzyme
O00555 BXGT003936 Voltage-dependent P/Q-type calcium channel subunit alpha-1A 773 reviewed Ion channel
O00571 BXGT003938 ATP-dependent RNA helicase DDX3X 1654 reviewed
O15120 BXGT004129 1-acyl-sn-glycerol-3-phosphate acyltransferase beta 10555 reviewed
O15305 BXGT004152 Phosphomannomutase 2 5373 reviewed Enzyme
O43766 BXGT004622 Lipoyl synthase, mitochondrial 11019 reviewed
O75844 BXGT005156 CAAX prenyl protease 1 homolog 10269 reviewed Enzyme
P00519 BXGT005570 Tyrosine-protein kinase ABL1 25 reviewed Kinase
P01100 BXGT005727 Proto-oncogene c-Fos 2353 reviewed Transcription factor
P01116 BXGT005733 GTPase KRas 3845 reviewed Enzyme modulator
P01911 BXGT005816 HLA class II histocompatibility antigen, DRB1-15 beta chain 3123 reviewed Immune response
P02458 BXGT005879 Collagen alpha-1(II) chain 1280 reviewed
P02511 BXGT005885 Alpha-crystallin B chain 1410 reviewed
P02545 BXGT005889 Prelamin-A/C 4000 reviewed
P02708 BXGT005927 Acetylcholine receptor subunit alpha 1134 reviewed Ion channel
P02765 BXGT005952 Alpha-2-HS-glycoprotein 197 reviewed Enzyme modulator
P03956 BXGT006120 Interstitial collagenase 4312 reviewed Enzyme
P04062 BXGT006140 Lysosomal acid glucosylceramidase 2629 reviewed
P04066 BXGT006142 Tissue alpha-L-fucosidase 2517 reviewed
P04264 BXGT006176 Keratin, type II cytoskeletal 1 3848 reviewed
P06753 BXGT006498 Tropomyosin alpha-3 chain 7170 reviewed Cellular structure
P07510 BXGT006631 Acetylcholine receptor subunit gamma 1146 reviewed Ion channel
P08236 BXGT006752 Beta-glucuronidase 2990 reviewed
P09936 BXGT006943 Ubiquitin carboxyl-terminal hydrolase isozyme L1 7345 reviewed Enzyme
P10809 BXGT007617 60 kDa heat shock protein, mitochondrial 3329 reviewed
P16435 BXGT008226 NADPH--cytochrome P450 reductase 5447 reviewed
P18074 BXGT008374 General transcription and DNA repair factor IIH helicase subunit XPD 2068 reviewed Enzyme
P18564 BXGT008414 Integrin beta-6 3694 reviewed Receptor
P20807 BXGT008601 Calpain-3 825 reviewed Enzyme
P21802 BXGT008691 Fibroblast growth factor receptor 2 2263 reviewed Kinase
P21817 BXGT008693 Ryanodine receptor 1 6261 reviewed Ion channel
P22304 BXGT008752 Iduronate 2-sulfatase 3423 reviewed
P28070 BXGT009230 Proteasome subunit beta type-4 5692 reviewed
P31040 BXGT009503 Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial 6389 reviewed Enzyme
P35475 BXGT009837 Alpha-L-iduronidase 3425 reviewed Enzyme
P35498 BXGT009838 Sodium channel protein type 1 subunit alpha 6323 reviewed Ion channel
P35499 BXGT009839 Sodium channel protein type 4 subunit alpha 6329 reviewed Ion channel
P35555 BXGT009845 Fibrillin-1 2200 reviewed Calcium-binding protein
P36021 BXGT009893 Monocarboxylate transporter 8 6567 reviewed Transporter
P36894 BXGT009939 Bone morphogenetic protein receptor type-1A 657 reviewed Kinase
P37173 BXGT009970 TGF-beta receptor type-2 7048 reviewed Kinase
P37231 BXGT009972 Peroxisome proliferator-activated receptor gamma 5468 reviewed Nuclear receptor
P40692 BXGT010195 DNA mismatch repair protein Mlh1 4292 reviewed Nucleic acid binding
P42336 BXGT010302 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform 5290 reviewed Kinase
P43004 BXGT010348 Excitatory amino acid transporter 2 6506 reviewed Transporter
P43026 BXGT010351 Growth/differentiation factor 5 8200 reviewed Signaling
P43246 BXGT010371 DNA mismatch repair protein Msh2 4436 reviewed Nucleic acid binding
P46100 BXGT010508 Transcriptional regulator ATRX 546 reviewed
P48051 BXGT010611 G protein-activated inward rectifier potassium channel 2 3763 reviewed Ion channel
P48058 BXGT010614 Glutamate receptor 4 2893 reviewed Ion channel
P49902 BXGT010758 Cytosolic purine 5'-nucleotidase 22978 reviewed Enzyme
P50897 BXGT010823 Palmitoyl-protein thioesterase 1 5538 reviewed Enzyme
P51684 BXGT010880 C-C chemokine receptor type 6 1235 reviewed G-protein coupled receptor
P52701 BXGT010943 DNA mismatch repair protein Msh6 2956 reviewed Nucleic acid binding
P54278 BXGT011038 Mismatch repair endonuclease PMS2 5395 reviewed Nucleic acid binding
P60880 BXGT011335 Synaptosomal-associated protein 25 6616 reviewed Transporter
P69905 BXGT011649 Hemoglobin subunit alpha 3040 reviewed
Q04721 BXGT012777 Neurogenic locus notch homolog protein 2 4853 reviewed
Q07001 BXGT012907 Acetylcholine receptor subunit delta 1144 reviewed Ion channel
Q09472 BXGT013038 Histone acetyltransferase p300 2033 reviewed
Q13155 BXGT013320 Aminoacyl tRNA synthase complex-interacting multifunctional protein 2 7965 reviewed
Q15149 BXGT013547 Plectin 5339 reviewed Cellular structure
Q6PI48 BXGT016471 Aspartate--tRNA ligase, mitochondrial 55157 reviewed Enzyme
Q6ZMI3 BXGT016627 Gliomedin 342035 reviewed
Q8IVA8 BXGT018342 Glutamate decarboxylase 1 (Brain, 67kDa) 2571 unreviewed
Q8NET8 BXGT018557 Transient receptor potential cation channel subfamily V member 3 162514 reviewed Ion channel
Q8WZ42 BXGT019023 Titin 7273 reviewed Kinase
Q92793 BXGT019374 CREB-binding protein 1387 reviewed
Q96AX1 BXGT019620 Vacuolar protein sorting-associated protein 33A 65082 reviewed Transporter
Q96BZ9 BXGT019629 TBC1 domain family member 20 128637 reviewed
Q96D31 BXGT019635 Calcium release-activated calcium channel protein 1 84876 reviewed Ion channel
Q96RE7 BXGT019725 Nucleus accumbens-associated protein 1 112939 reviewed
Q99259 BXGT019915 Glutamate decarboxylase 1 2571 reviewed Enzyme
Q9HBA0 BXGT020516 Transient receptor potential cation channel subfamily V member 4 59341 reviewed Ion channel
Q9NP72 BXGT021144 Ras-related protein Rab-18 22931 reviewed
Q9NSE4 BXGT021207 Isoleucine--tRNA ligase, mitochondrial 55699 reviewed Enzyme
Q9P032 BXGT021286 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 4 29078 reviewed
Q9UBV7 BXGT021665 Beta-1,4-galactosyltransferase 7 11285 reviewed
Q9Y2M0 BXGT022241 Fanconi-associated nuclease 1 22909 reviewed
Q9Y3C8 BXGT022256 Ubiquitin-fold modifier-conjugating enzyme 1 51506 reviewed
Q9Y3Z3 BXGT022268 Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 25939 reviewed
Q9UBP0 BXGT023601 Spastin 6683 reviewed Cellular structure
O95140 BXGT024482 Mitofusin-2 9927 reviewed Enzyme
Q9BYC5 BXGT025656 Alpha-(1,6)-fucosyltransferase 2530 reviewed
Q96MF2 BXGT025769 SH3 and cysteine-rich domain-containing protein 3 246329 reviewed
The  disease-related  compounds
Compounds
BXGC Id Compound Name Structure Molecular Weight Number of targets?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease
The  disease-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compounds in food?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease