Showing entry for Equilibrative nucleoside transporter 1


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT019964
Protein NameEquilibrative nucleoside transporter 1
Uniport IdQ99808
GeneSLC29A1
Gene Id2030
DomainNucleoside_tran
Pfam PF01733  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
6. Human Diseases 6.5 Substance dependence hsa05034 Alcoholism
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0032238 adenosine transport
Biological Process GO:0071333 cellular response to glucose stimulus
Biological Process GO:0071456 cellular response to hypoxia
Biological Process GO:0060079 excitatory postsynaptic potential
Biological Process GO:0007595 lactation
Biological Process GO:0098810 neurotransmitter reuptake
Biological Process GO:0006836 neurotransmitter transport
Biological Process GO:0001504 neurotransmitter uptake
Biological Process GO:0006139 nucleobase-containing compound metabolic process
Biological Process GO:1901642 nucleoside transmembrane transport
Biological Process GO:0015858 nucleoside transport
Biological Process GO:0015860 purine nucleoside transmembrane transport
Biological Process GO:0072531 pyrimidine-containing compound transmembrane transport
Biological Process GO:0030431 sleep
Biological Process GO:0150104 transport across blood-brain barrier
Biological Process GO:0015862 uridine transport
molecular function GO:0005326 neurotransmitter transmembrane transporter activity
molecular function GO:0005337 nucleoside transmembrane transporter activity
molecular function GO:0015211 purine nucleoside transmembrane transporter activity
molecular function GO:0015213 uridine transmembrane transporter activity
cellular component GO:0016324 apical plasma membrane
cellular component GO:0016323 basolateral plasma membrane
cellular component GO:0016021 integral component of membrane
cellular component GO:0005887 integral component of plasma membrane
cellular component GO:0016020 membrane
cellular component GO:0005886 plasma membrane
cellular component GO:0098794 postsynapse
cellular component GO:0098793 presynapse
Reactome
Pathway Id Pathway Name
R-HSA-382551 Transport of small molecules
R-HSA-425397 Transport of vitamins, nucleosides, and related molecules
R-HSA-425407 SLC-mediated transmembrane transport
R-HSA-83936 Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0001956 BXGD000092 Alcohol Use Disorder Chemically-Induced Disorders; Mental Disorders
C0001973 BXGD000095 Alcoholic Intoxication, Chronic Chemically-Induced Disorders; Mental Disorders
C0002395 BXGD000111 Alzheimer's Disease Nervous System Diseases; Mental Disorders
C0002871 BXGD000132 Anemia Hemic and Lymphatic Diseases
C0003504 BXGD000202 Aortic Valve Insufficiency Cardiovascular Diseases
C0006266 BXGD000382 Bronchospasm Respiratory Tract Diseases
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0007102 BXGD000425 Malignant tumor of colon Digestive System Diseases; Neoplasms
C0007131 BXGD000441 Non-Small Cell Lung Carcinoma Neoplasms; Respiratory Tract Diseases
C0007222 BXGD000454 Cardiovascular Diseases Cardiovascular Diseases
C0007786 BXGD000486 Brain Ischemia Nervous System Diseases; Cardiovascular Diseases
C0009402 BXGD000605 Colorectal Carcinoma Digestive System Diseases; Neoplasms
C0010674 BXGD000683 Cystic Fibrosis Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Digestive System Diseases; Respiratory Tract Diseases
C0011853 BXGD000752 Diabetes Mellitus, Experimental Nutritional and Metabolic Diseases; Endocrine System Diseases
C0013404 BXGD000833 Dyspnea Pathological Conditions, Signs and Symptoms; Respiratory Tract Diseases
C0014761 BXGD000947 Erythroblastosis, Fetal Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Immune System Diseases; Hemic and Lymphatic Diseases
C0017638 BXGD001132 Glioma Neoplasms
C0018923 BXGD001248 Hemangiosarcoma Neoplasms
C0019196 BXGD001301 Hepatitis C Digestive System Diseases; Infections
C0019348 BXGD001325 Herpes Simplex Infections Infections; Skin and Connective Tissue Diseases
C0019829 BXGD001350 Hodgkin Disease Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0020179 BXGD001363 Huntington Disease Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases; Mental Disorders
C0020498 BXGD001407 Hyperostosis, Diffuse Idiopathic Skeletal Musculoskeletal Diseases
C0020538 BXGD001422 Hypertensive disease Cardiovascular Diseases
C0021390 BXGD001503 Inflammatory Bowel Diseases Digestive System Diseases
C0022660 BXGD001571 Kidney Failure, Acute Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0023269 BXGD001627 leiomyosarcoma Neoplasms
C0023418 BXGD001642 leukemia Neoplasms
C0023452 BXGD001651 Childhood Acute Lymphoblastic Leukemia Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0023467 BXGD001658 Leukemia, Myelocytic, Acute Neoplasms
C0023530 BXGD001683 Leukopenia Hemic and Lymphatic Diseases
C0023787 BXGD001698 Lipodystrophy Nutritional and Metabolic Diseases; Skin and Connective Tissue Diseases
C0024115 BXGD001732 Lung diseases Respiratory Tract Diseases
C0024121 BXGD001735 Lung Neoplasms Neoplasms; Respiratory Tract Diseases
C0027651 BXGD002009 Neoplasms Neoplasms
C0027947 BXGD002061 Neutropenia Hemic and Lymphatic Diseases
C0029463 BXGD002160 Osteosarcoma Neoplasms
C0030297 BXGD002204 Pancreatic Neoplasm Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0035204 BXGD002511 Respiration Disorders Respiratory Tract Diseases
C0035242 BXGD002521 Respiratory Tract Diseases Respiratory Tract Diseases
C0036572 BXGD002625 Seizures Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0037317 BXGD002689 Sleep disturbances Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
C0040034 BXGD002836 Thrombocytopenia Hemic and Lymphatic Diseases
C0085207 BXGD003140 Gestational Diabetes Nutritional and Metabolic Diseases; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C0151744 BXGD003469 Myocardial Ischemia Cardiovascular Diseases
C0220668 BXGD004317 Congenital contractural arachnodactyly Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0233514 BXGD004584 Abnormal behavior Behavior and Behavior Mechanisms
C0233794 BXGD004618 Memory impairment Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Behavior and Behavior Mechanisms
C0235974 BXGD004796 Pancreatic carcinoma Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0236664 BXGD004818 Alcohol-Related Disorders Chemically-Induced Disorders; Mental Disorders
C0236970 BXGD004843 Alcohol-Induced Disorders Chemically-Induced Disorders
C0278488 BXGD006515 Carcinoma breast stage IV
C0278592 BXGD006544 Adult Angiosarcoma Neoplasms
C0278607 BXGD006548 Adult Leiomyosarcoma Neoplasms
C0279986 BXGD006705 Childhood Leiomyosarcoma Neoplasms
C0279988 BXGD006707 Childhood Angiosarcoma Neoplasms
C0281361 BXGD006774 Adenocarcinoma of pancreas Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0334634 BXGD007144 Malignant lymphoma, lymphocytic, intermediate differentiation, diffuse Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0345905 BXGD007746 Intrahepatic Cholangiocarcinoma Neoplasms
C0346647 BXGD007832 Malignant neoplasm of pancreas Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0393574 BXGD008095 Huntington Disease, Late Onset Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases; Mental Disorders
C0524910 BXGD009248 Hepatitis C, Chronic Digestive System Diseases; Infections
C0542476 BXGD009276 Forgetful Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
C0585442 BXGD009593 Osteosarcoma of bone Neoplasms
C0586323 BXGD009603 Alcohol Withdrawal Seizures Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Chemically-Induced Disorders
C0685938 BXGD009829 Malignant neoplasm of gastrointestinal tract Digestive System Diseases; Neoplasms
C0699790 BXGD009866 Colon Carcinoma Digestive System Diseases; Neoplasms
C0742343 BXGD010061 Acute Chest Syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Respiratory Tract Diseases; Hemic and Lymphatic Diseases
C0751207 BXGD010348 Akinetic-Rigid Variant of Huntington Disease Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases; Mental Disorders
C0751208 BXGD010349 Juvenile Huntington Disease Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases; Mental Disorders
C0751868 BXGD010620 Alcohol Withdrawal-Induced Major Motor Seizure Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Chemically-Induced Disorders
C0751869 BXGD010621 Status Epilepticus, Alcohol Withdrawal-Induced Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Chemically-Induced Disorders
C0851578 BXGD010925 Sleep Disorders Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders
C0854776 BXGD011031 Pancreatic carcinoma non-resectable Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0947785 BXGD011495 [D]Sleep disturbances (& [hypersomnia] or [insomnia])
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C1332977 BXGD012569 Childhood Leukemia Neoplasms
C1332986 BXGD012574 Childhood Osteosarcoma Neoplasms
C1335302 BXGD012775 Pancreatic Ductal Adenocarcinoma Digestive System Diseases; Neoplasms; Endocrine System Diseases
C1410087 BXGD013041 Spine stiffness
C1832661 BXGD013866 ANOPHTHALMIA AND PULMONARY HYPOPLASIA Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases; Respiratory Tract Diseases
C2347761 BXGD017049 Childhood Myelodysplastic Syndrome Hemic and Lymphatic Diseases
C2751719 BXGD017735 ALCOHOL DEPENDENCE, PROTECTION AGAINST
C3463824 BXGD018899 MYELODYSPLASTIC SYNDROME Hemic and Lymphatic Diseases
C3854222 BXGD019826 Human immunodeficiency virus (HIV) II infection category B1
C3887915 BXGD019927 AERODIGESTIVE TRACT CANCER, SQUAMOUS CELL, ALCOHOL-RELATED, PROTECTION AGAINST
C3888194 BXGD019955 MIXED LINEAGE LEUKEMIA
C3900098 BXGD020106 Adult Myelodysplastic Syndrome Hemic and Lymphatic Diseases
C4023620 BXGD021230 Blood group antigen abnormality
C4054727 BXGD021988 Infant Acute Lymphoblastic Leukemia Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C4284013 BXGD022428 Primary cholangiocarcinoma of intrahepatic biliary tract Neoplasms
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000434 Ethanol 46.07
BXGC0002605 Adenosine 267.24
BXGC0003788 Phlororrhizin 436.41
BXGC0028471 Monoolein 356.29
BXGC0044087 Uridine 244.07
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein