Showing entry for Cholangitis, Sclerosing


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Disease Information
BXGD IdBXGD000528
Disease NameCholangitis, Sclerosing
Disease CUI IdC0008313
MeSH Codes C06  
Disease Class NameDigestive System Diseases
Semantic TypeDisease or Syndrome
Human Phenotype Ontology Id HP:0025031   HP:0002715  
Human Phenotype Ontology TermAbnormality of the digestive system; Abnormality of the immune system
Disease Ontology Id DOID:7  
Disease Ontology Class Namedisease of anatomical entity
Disorder Network disorder-protein-compound-food associations
The  disease-related  target proteins
Proteins
Uniport Id BXGT Id Protein Name Gene Status Protein Class
Uniport Id BXGT Id Protein name Gene Status Protein class
O00206 BXGT003894 Toll-like receptor 4 7099 reviewed
O00462 BXGT003925 Beta-mannosidase 4126 reviewed Enzyme
O00482 BXGT003929 Nuclear receptor subfamily 5 group A member 2 2494 reviewed Nuclear receptor
O43521 BXGT004598 Bcl-2-like protein 11 10018 reviewed
O75460 BXGT005127 Serine/threonine-protein kinase/endoribonuclease IRE1 2081 reviewed Kinase
O95407 BXGT005380 Tumor necrosis factor receptor superfamily member 6B 8771 reviewed
O95644 BXGT005389 Nuclear factor of activated T-cells, cytoplasmic 1 4772 reviewed Transcription factor
P00749 BXGT005641 Urokinase-type plasminogen activator 5328 reviewed Enzyme
P01589 BXGT005773 Interleukin-2 receptor subunit alpha 3559 reviewed Receptor
P01911 BXGT005816 HLA class II histocompatibility antigen, DRB1-15 beta chain 3123 reviewed Immune response
P01920 BXGT005817 HLA class II histocompatibility antigen, DQ beta 1 chain 3119 reviewed Immune response
P05362 BXGT006350 Intercellular adhesion molecule 1 3383 reviewed
P05771 BXGT006384 Protein kinase C beta type 5579 reviewed Kinase
P08842 BXGT006830 Steryl-sulfatase 412 reviewed Enzyme
P08887 BXGT006835 Interleukin-6 receptor subunit alpha 3570 reviewed Signaling
P13501 BXGT007917 C-C motif chemokine 5 6352 reviewed Signaling
P13569 BXGT007923 Cystic fibrosis transmembrane conductance regulator 1080 reviewed Ion channel
P14921 BXGT008068 Protein C-ets-1 2113 reviewed Transcription factor
P15884 BXGT008166 Transcription factor 4 6925 reviewed Transcription factor
P17706 BXGT008330 Tyrosine-protein phosphatase non-receptor type 2 5771 reviewed
P19438 BXGT008480 Tumor necrosis factor receptor superfamily member 1A 7132 reviewed
P19838 BXGT008526 Nuclear factor NF-kappa-B p105 subunit 4790 reviewed Transcription factor
P20701 BXGT008591 Integrin alpha-L 3683 reviewed
P20711 BXGT008594 Aromatic-L-amino-acid decarboxylase 1644 reviewed
P21439 BXGT008649 Phosphatidylcholine translocator ABCB4 5244 reviewed Transporter
P21580 BXGT008666 Tumor necrosis factor alpha-induced protein 3 7128 reviewed Enzyme
P23443 BXGT008866 Ribosomal protein S6 kinase beta-1 6198 reviewed Kinase
P24298 BXGT008960 Alanine aminotransferase 1 2875 reviewed Enzyme
P25942 BXGT009079 Tumor necrosis factor receptor superfamily member 5 958 reviewed
P29597 BXGT009367 Non-receptor tyrosine-protein kinase TYK2 7297 reviewed Kinase
P35222 BXGT009799 Catenin beta-1 1499 reviewed
P35228 BXGT009800 Nitric oxide synthase, inducible 4843 reviewed
P35869 BXGT009877 Aryl hydrocarbon receptor 196 reviewed Transcription factor
P38484 BXGT010042 Interferon gamma receptor 2 3460 reviewed Receptor
P40763 BXGT010202 Signal transducer and activator of transcription 3 6774 reviewed Nucleic acid binding
P41597 BXGT010268 C-C chemokine receptor type 2 729230 reviewed
P46531 BXGT010526 Neurogenic locus notch homolog protein 1 4851 reviewed
P50591 BXGT010814 Tumor necrosis factor ligand superfamily member 10 8743 reviewed Signaling
P51681 BXGT010878 C-C chemokine receptor type 5 1234 reviewed G-protein coupled receptor
P55786 BXGT011125 Puromycin-sensitive aminopeptidase 9520 reviewed Enzyme
P58335 BXGT011233 Anthrax toxin receptor 2 118429 reviewed Receptor
P60568 BXGT011315 Interleukin-2 3558 reviewed
P62736 BXGT011452 Actin, aortic smooth muscle 59 reviewed Cellular structure
P68036 BXGT011572 Ubiquitin-conjugating enzyme E2 L3 7332 reviewed Enzyme
P84022 BXGT012027 Mothers against decapentaplegic homolog 3 4088 reviewed Transcription factor
Q04759 BXGT012781 Protein kinase C theta type 5588 reviewed Kinase
Q13478 BXGT013362 Interleukin-18 receptor 1 8809 reviewed Receptor
Q14145 BXGT013448 Kelch-like ECH-associated protein 1 9817 reviewed
Q14397 BXGT013467 Glucokinase regulatory protein 2646 reviewed
Q14469 BXGT013473 Transcription factor HES-1 3280 reviewed Transcription factor
Q15831 BXGT013604 Serine/threonine-protein kinase STK11 6794 reviewed Kinase
Q16236 BXGT013624 Nuclear factor erythroid 2-related factor 2 4780 reviewed Enzyme
Q16665 BXGT013653 Hypoxia-inducible factor 1-alpha 3091 reviewed Transcription factor
Q3MIT2 BXGT014505 Putative tRNA pseudouridine synthase Pus10 150962 reviewed
Q5S007 BXGT015650 Leucine-rich repeat serine/threonine-protein kinase 2 120892 reviewed Kinase
Q5VWK5 BXGT015891 Interleukin-23 receptor 149233 reviewed Signaling
Q5Y7D3 BXGT015912 HLA class II histocompatibility antigen DQ beta chain 3119 unreviewed
Q676U5 BXGT016177 Autophagy-related protein 16-1 55054 reviewed
Q6IB77 BXGT016325 Glycine N-acyltransferase 10249 reviewed
Q6P179 BXGT016440 Endoplasmic reticulum aminopeptidase 2 64167 reviewed Enzyme
Q86Z02 BXGT017638 Homeodomain-interacting protein kinase 1 204851 reviewed Kinase
Q8IY67 BXGT018363 Ribonucleoprotein PTB-binding 1 125950 reviewed Nucleic acid binding
Q8TDU6 BXGT018814 G-protein coupled bile acid receptor 1 151306 reviewed G-protein coupled receptor
Q8WUI4 BXGT018992 Histone deacetylase 7 51564 reviewed Epigenetic regulator
Q92956 BXGT019399 Tumor necrosis factor receptor superfamily member 14 8764 reviewed
Q99497 BXGT019926 Protein/nucleic acid deglycase DJ-1 11315 reviewed Enzyme
Q99685 BXGT019948 Monoglyceride lipase 11343 reviewed Enzyme
Q99700 BXGT019949 Ataxin-2 6311 reviewed Nucleic acid binding
Q9BZL6 BXGT020199 Serine/threonine-protein kinase D2 25865 reviewed Kinase
Q9H0K1 BXGT020438 Serine/threonine-protein kinase SIK2 23235 reviewed Kinase
Q9HC29 BXGT020526 Nucleotide-binding oligomerization domain-containing protein 2 64127 reviewed Enzyme
Q9HC97 BXGT020527 G-protein coupled receptor 35 2859 reviewed G-protein coupled receptor
Q9NZ08 BXGT021266 Endoplasmic reticulum aminopeptidase 1 51752 reviewed Enzyme
Q9NZI2 BXGT021272 Kv channel-interacting protein 1 30820 reviewed Ion channel
Q9UKU7 BXGT021749 Isobutyryl-CoA dehydrogenase, mitochondrial 27034 reviewed Enzyme
Q9ULJ6 BXGT021761 Zinc finger MIZ domain-containing protein 1 57178 reviewed
Q9Y2R2 BXGT022243 Tyrosine-protein phosphatase non-receptor type 22 26191 reviewed
Q9Y6K1 BXGT022331 DNA (cytosine-5)-methyltransferase 3A 1788 reviewed
Q8IVT5 BXGT026146 Kinase suppressor of Ras 1 8844 reviewed Kinase
The  disease-related  compounds
Compounds
BXGC Id Compound Name Structure Molecular Weight Number of targets?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease
The  disease-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compounds in food?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease