adisease

Showing entry for Agitation

General Disease Information
BXGD Id	BXGD003214
Disease Name	Agitation
Disease CUI Id	C0085631
MeSH Codes	C10 F03 F01
Disease Class Name	Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
Semantic Type	Sign or Symptom
Human Phenotype Ontology Id	HP:0000707
Human Phenotype Ontology Term	Abnormality of the nervous system
Disease Ontology Id
Disease Ontology Class Name
Disorder Network	disorder-protein-compound-food associations

The disease-related target proteins

Proteins

Uniport Id	BXGT Id	Protein Name	Gene	Status	Protein Class
Uniport Id	BXGT Id	Protein name	Gene	Status	Protein class
O00555	BXGT003936	Voltage-dependent P/Q-type calcium channel subunit alpha-1A	773	reviewed	Ion channel
O43464	BXGT004595	Serine protease HTRA2, mitochondrial	27429	reviewed
O43612	BXGT004605	Orexin	3060	reviewed
O60260	BXGT004864	E3 ubiquitin-protein ligase parkin	5071	reviewed	Enzyme
O75899	BXGT005161	Gamma-aminobutyric acid type B receptor subunit 2	9568	reviewed	G-protein coupled receptor
O75914	BXGT005165	Serine/threonine-protein kinase PAK 3	5063	reviewed	Kinase
P00441	BXGT005540	Superoxide dismutase [Cu-Zn]	6647	reviewed	Enzyme
P03950	BXGT006116	Angiogenin	283	reviewed
P04062	BXGT006140	Lysosomal acid glucosylceramidase	2629	reviewed
P04745	BXGT006255	Alpha-amylase 1	278	reviewed
P05067	BXGT006306	Amyloid-beta precursor protein	351	reviewed	Enzyme modulator
P07737	BXGT006663	Profilin-1	5216	reviewed
P08069	BXGT006723	Insulin-like growth factor 1 receptor	3480	reviewed	Kinase
P09466	BXGT006892	Glycodelin	5047	reviewed	Enzyme
P09651	BXGT006913	Heterogeneous nuclear ribonucleoprotein A1	3178	reviewed
P09936	BXGT006943	Ubiquitin carboxyl-terminal hydrolase isozyme L1	7345	reviewed	Enzyme
P10644	BXGT007597	cAMP-dependent protein kinase type I-alpha regulatory subunit	5573	reviewed
P14920	BXGT008067	D-amino-acid oxidase	1610	reviewed
P16473	BXGT008234	Thyrotropin receptor	7253	reviewed	G-protein coupled receptor
P23560	BXGT008883	Brain-derived neurotrophic factor	627	reviewed	Signaling
P24752	BXGT008993	Acetyl-CoA acetyltransferase, mitochondrial	38	reviewed	Enzyme
P27169	BXGT009161	Serum paraoxonase/arylesterase 1	5444	reviewed
P35222	BXGT009799	Catenin beta-1	1499	reviewed
P37840	BXGT010015	Alpha-synuclein	6622	reviewed	Transporter
P41235	BXGT010241	Hepatocyte nuclear factor 4-alpha	3172	reviewed	Nuclear receptor
P42858	BXGT010341	Huntingtin	3064	reviewed
P49768	BXGT010740	Presenilin-1	5663	reviewed	Enzyme
P49810	BXGT010747	Presenilin-2	5664	reviewed	Enzyme
P51687	BXGT010882	Sulfite oxidase, mitochondrial	6821	reviewed
P54764	BXGT011078	Ephrin type-A receptor 4	2043	reviewed	Kinase
P55072	BXGT011103	Transitional endoplasmic reticulum ATPase	7415	reviewed
P63092	BXGT011495	Guanine nucleotide-binding protein G(s) subunit alpha isoforms short	2778	reviewed
Q01959	BXGT012624	Sodium-dependent dopamine transporter	6531	reviewed	Transporter
Q03393	BXGT012711	6-pyruvoyl tetrahydrobiopterin synthase	5805	reviewed
Q04637	BXGT012771	Eukaryotic translation initiation factor 4 gamma 1	1981	reviewed	Nucleic acid binding
Q09428	BXGT013036	ATP-binding cassette sub-family C member 8	6833	reviewed	Transporter
Q13148	BXGT013318	TAR DNA-binding protein 43	23435	reviewed
Q13501	BXGT013365	Sequestosome-1	8878	reviewed
Q13541	BXGT013371	Eukaryotic translation initiation factor 4E-binding protein 1	1978	reviewed	Nucleic acid binding
Q13554	BXGT013374	Calcium/calmodulin-dependent protein kinase type II subunit beta	816	reviewed	Kinase
Q14203	BXGT013455	Dynactin subunit 1	1639	reviewed	Chaperone
Q14654	BXGT013495	ATP-sensitive inward rectifier potassium channel 11	3767	reviewed	Ion channel
Q15303	BXGT013557	Receptor tyrosine-protein kinase erbB-4	2066	reviewed	Kinase
Q5S007	BXGT015650	Leucine-rich repeat serine/threonine-protein kinase 2	120892	reviewed	Kinase
Q8N159	BXGT018496	N-acetylglutamate synthase, mitochondrial	162417	reviewed
Q96PY6	BXGT019712	Serine/threonine-protein kinase Nek1	4750	reviewed	Kinase
Q96QK1	BXGT019720	Vacuolar protein sorting-associated protein 35	55737	reviewed	Transporter
Q99497	BXGT019926	Protein/nucleic acid deglycase DJ-1	11315	reviewed	Enzyme
Q99700	BXGT019949	Ataxin-2	6311	reviewed	Nucleic acid binding
Q99714	BXGT019954	3-hydroxyacyl-CoA dehydrogenase type-2	3028	reviewed	Enzyme
Q9BQI3	BXGT020113	Eukaryotic translation initiation factor 2-alpha kinase 1	27102	reviewed	Kinase
Q9BXM7	BXGT020172	Serine/threonine-protein kinase PINK1, mitochondrial	65018	reviewed	Kinase
Q9HCR9	BXGT020537	Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A	50940	reviewed
Q9NYA1	BXGT021254	Sphingosine kinase 1	8877	reviewed	Kinase
Q9UHD2	BXGT021697	Serine/threonine-protein kinase TBK1	29110	reviewed	Kinase
Q9UBP0	BXGT023601	Spastin	6683	reviewed	Cellular structure
Q53GS7	BXGT023762	Nucleoporin GLE1	2733	reviewed	Transporter

The disease-related compounds

Compounds

BXGC Id	Compound Name	Structure	Molecular Weight	Number of targets^{?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease}

The disease-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compounds in food^{?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease}