adisease

Showing entry for Poor speech

General Disease Information
BXGD Id	BXGD014916
Disease Name	Poor speech
Disease CUI Id	C1848207
MeSH Codes	C23 C10
Disease Class Name	Pathological Conditions, Signs and Symptoms; Nervous System Diseases
Semantic Type	Finding
Human Phenotype Ontology Id	HP:0000707
Human Phenotype Ontology Term	Abnormality of the nervous system
Disease Ontology Id
Disease Ontology Class Name
Disorder Network	disorder-protein-compound-food associations

The disease-related target proteins

Proteins

Uniport Id	BXGT Id	Protein Name	Gene	Status	Protein Class
Uniport Id	BXGT Id	Protein name	Gene	Status	Protein class
O00189	BXGT003891	AP-4 complex subunit mu-1	9179	reviewed	Extracellular structure
O14764	BXGT004094	Gamma-aminobutyric acid receptor subunit delta	2563	reviewed	Ion channel
O15247	BXGT004142	Chloride intracellular channel protein 2	1193	reviewed	Ion channel
O15305	BXGT004152	Phosphomannomutase 2	5373	reviewed	Enzyme
O15409	BXGT004166	Forkhead box protein P2	93986	reviewed
O43424	BXGT004592	Glutamate receptor ionotropic, delta-2	2895	reviewed	Ion channel
O60488	BXGT004878	Long-chain-fatty-acid--CoA ligase 4	2182	reviewed	Enzyme
O75914	BXGT005165	Serine/threonine-protein kinase PAK 3	5063	reviewed	Kinase
O94903	BXGT005339	Pyridoxal phosphate homeostasis protein	11212	reviewed
P01133	BXGT005736	Pro-epidermal growth factor	1950	reviewed
P04350	BXGT006193	Tubulin beta-4A chain	10382	reviewed	Cellular structure
P07333	BXGT006602	Macrophage colony-stimulating factor 1 receptor	1436	reviewed	Kinase
P08236	BXGT006752	Beta-glucuronidase	2990	reviewed
P10636	BXGT007596	Microtubule-associated protein tau	4137	reviewed
P15311	BXGT008106	Ezrin	7430	reviewed	Cellular structure
P27708	BXGT009202	CAD protein	790	reviewed	Enzyme
P28331	BXGT009252	NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial	4719	reviewed	Enzyme
P35222	BXGT009799	Catenin beta-1	1499	reviewed
P48547	BXGT010643	Potassium voltage-gated channel subfamily C member 1	3746	reviewed	Ion channel
P49591	BXGT010715	Serine--tRNA ligase, cytoplasmic	6301	reviewed	Enzyme
P49768	BXGT010740	Presenilin-1	5663	reviewed	Enzyme
P49914	BXGT010762	5-formyltetrahydrofolate cyclo-ligase	10588	reviewed	Enzyme
P50052	BXGT010768	Type-2 angiotensin II receptor	186	reviewed	G-protein coupled receptor
P50135	BXGT010776	Histamine N-methyltransferase	3176	reviewed
P51531	BXGT010851	Probable global transcription activator SNF2L2	6595	reviewed	Epigenetic regulator
P51812	BXGT010893	Ribosomal protein S6 kinase alpha-3	6197	reviewed	Kinase
P55072	BXGT011103	Transitional endoplasmic reticulum ATPase	7415	reviewed
P55263	BXGT011115	Adenosine kinase	132	reviewed	Kinase
P56556	BXGT011179	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6	4700	reviewed	Enzyme
P58400	BXGT011235	Neurexin-1-beta	9378	reviewed
P60880	BXGT011335	Synaptosomal-associated protein 25	6616	reviewed	Transporter
P61978	BXGT011399	Heterogeneous nuclear ribonucleoprotein K	3190	reviewed	Enzyme
P63000	BXGT011481	Ras-related C3 botulinum toxin substrate 1	5879	reviewed	Enzyme modulator
P98155	BXGT012226	Very low-density lipoprotein receptor	7436	reviewed
Q01105	BXGT012569	Protein SET	6418	reviewed	Enzyme modulator
Q11203	BXGT013218	CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase	6487	reviewed
Q12791	BXGT013264	Calcium-activated potassium channel subunit alpha-1	3778	reviewed	Ion channel
Q13002	BXGT013303	Glutamate receptor ionotropic, kainate 2	2898	reviewed	Ion channel
Q13153	BXGT013319	Serine/threonine-protein kinase PAK 1	5058	reviewed	Kinase
Q13303	BXGT013336	Voltage-gated potassium channel subunit beta-2	8514	reviewed	Ion channel
Q13501	BXGT013365	Sequestosome-1	8878	reviewed
Q13509	BXGT013366	Tubulin beta-3 chain	10381	reviewed	Cellular structure
Q14118	BXGT013444	Dystroglycan	1605	reviewed	Receptor
Q14353	BXGT013463	Guanidinoacetate N-methyltransferase	2593	reviewed
Q14683	BXGT013500	Structural maintenance of chromosomes protein 1A	8243	reviewed
Q15233	BXGT013552	Non-POU domain-containing octamer-binding protein	4841	reviewed	Nucleic acid binding
Q6MZM0	BXGT016375	Hephaestin-like protein 1	341208	reviewed
Q7Z3B3	BXGT017249	KAT8 regulatory NSL complex subunit 1	284058	reviewed
Q8N159	BXGT018496	N-acetylglutamate synthase, mitochondrial	162417	reviewed
Q92794	BXGT019375	Histone acetyltransferase KAT6A	7994	reviewed	Enzyme
Q92796	BXGT019376	Disks large homolog 3	1741	reviewed
Q96IV0	BXGT019677	Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase	55768	reviewed	Enzyme
Q96SW2	BXGT019743	Protein cereblon	51185	reviewed	Enzyme
Q99250	BXGT019913	Sodium channel protein type 2 subunit alpha	6326	reviewed	Ion channel
Q9BY41	BXGT020180	Histone deacetylase 8	55869	reviewed	Epigenetic regulator
Q9H8M5	BXGT020496	Metal transporter CNNM2	54805	reviewed
Q9HD42	BXGT020543	Charged multivesicular body protein 1a	5119	reviewed
Q9NS87	BXGT021201	Kinesin-like protein KIF15	56992	reviewed	Cellular structure
Q9NX46	BXGT021243	ADP-ribose glycohydrolase ARH3	54936	reviewed
Q9NYG8	BXGT021257	Potassium channel subfamily K member 4	50801	reviewed	Ion channel
Q9NZN1	BXGT021279	Interleukin-1 receptor accessory protein-like 1	11141	reviewed	Receptor
Q9P0J0	BXGT021287	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13	51079	reviewed	Enzyme
Q9UGL1	BXGT021685	Lysine-specific demethylase 5B	10765	reviewed	Epigenetic regulator
Q9UGM6	BXGT021687	Tryptophan--tRNA ligase, mitochondrial	10352	reviewed
Q9UKE5	BXGT021741	TRAF2 and NCK-interacting protein kinase	23043	reviewed	Kinase
Q9UKM7	BXGT021747	Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase	11253	reviewed	Chaperone
Q9Y259	BXGT022219	Choline/ethanolamine kinase	1120	reviewed	Kinase
Q96C86	BXGT022803	m7GpppX diphosphatase	28960	reviewed	Enzyme
Q9H9S5	BXGT024623	Fukutin-related protein	79147	reviewed
P51608	BXGT025073	Methyl-CpG-binding protein 2	4204	reviewed	Epigenetic regulator
Q96DA2	BXGT025522	Ras-related protein Rab-39B	116442	reviewed
Q05086	BXGT025648	Ubiquitin-protein ligase E3A	7337	reviewed
Q9UQE7	BXGT025899	Structural maintenance of chromosomes protein 3	9126	reviewed
Q6UVJ0	BXGT026024	Spindle assembly abnormal protein 6 homolog	163786	reviewed
Q8WXI2	BXGT026145	Connector enhancer of kinase suppressor of ras 2	22866	reviewed

The disease-related compounds

Compounds

BXGC Id	Compound Name	Structure	Molecular Weight	Number of targets^{?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease}

The disease-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compounds in food^{?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease}