Showing entry for Acute kidney injury


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Disease Information
BXGD IdBXGD017182
Disease NameAcute kidney injury
Disease CUI IdC2609414
MeSH Codes C13   C12  
Disease Class NameFemale Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
Semantic TypeInjury or Poisoning
Human Phenotype Ontology Id HP:0000119  
Human Phenotype Ontology TermAbnormality of the genitourinary system
Disease Ontology Id DOID:7  
Disease Ontology Class Namedisease of anatomical entity
Disorder Network disorder-protein-compound-food associations
The  disease-related  target proteins
Proteins
Uniport Id BXGT Id Protein Name Gene Status Protein Class
Uniport Id BXGT Id Protein name Gene Status Protein class
O00206 BXGT003894 Toll-like receptor 4 7099 reviewed
O15244 BXGT004140 Solute carrier family 22 member 2 6582 reviewed Transporter
O15245 BXGT004141 Solute carrier family 22 member 1 6580 reviewed Transporter
O15379 BXGT004159 Histone deacetylase 3 8841 reviewed Epigenetic regulator
O60603 BXGT004887 Toll-like receptor 2 7097 reviewed
O60656 BXGT004889 UDP-glucuronosyltransferase 1-9 54600 reviewed
O95169 BXGT005356 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial 4714 reviewed Enzyme
O95398 BXGT005378 Rap guanine nucleotide exchange factor 3 10411 reviewed Enzyme modulator
P00390 BXGT005526 Glutathione reductase, mitochondrial 2936 reviewed Enzyme
P00441 BXGT005540 Superoxide dismutase [Cu-Zn] 6647 reviewed Enzyme
P00450 BXGT005544 Ceruloplasmin 1356 reviewed Enzyme
P00492 BXGT005556 Hypoxanthine-guanine phosphoribosyltransferase 3251 reviewed Enzyme
P00505 BXGT005560 Aspartate aminotransferase, mitochondrial 2806 reviewed
P00533 BXGT005575 Epidermal growth factor receptor 1956 reviewed Kinase
P00747 BXGT005639 Plasminogen 5340 reviewed Enzyme
P00751 BXGT005643 Complement factor B 629 reviewed
P01009 BXGT005714 Alpha-1-antitrypsin 5265 reviewed Enzyme modulator
P01023 BXGT005718 Alpha-2-macroglobulin 2 reviewed Enzyme modulator
P01024 BXGT005719 Complement C3 718 reviewed Enzyme modulator
P01034 BXGT005721 Cystatin-C 1471 reviewed
P01042 BXGT005722 Kininogen-1 3827 reviewed Enzyme modulator
P01133 BXGT005736 Pro-epidermal growth factor 1950 reviewed
P01137 BXGT005737 Transforming growth factor beta-1 proprotein 7040 reviewed Signaling
P01189 BXGT005742 Pro-opiomelanocortin 5443 reviewed
P01308 BXGT005749 Insulin 3630 reviewed
P01375 BXGT005753 Tumor necrosis factor 7124 reviewed Signaling
P01584 BXGT005772 Interleukin-1 beta 3553 reviewed
P02144 BXGT005853 Myoglobin 4151 reviewed
P02671 BXGT005914 Fibrinogen alpha chain 2243 reviewed
P02741 BXGT005936 C-reactive protein 1401 reviewed
P02751 BXGT005943 Fibronectin 2335 reviewed Signaling
P02760 BXGT005948 Protein AMBP 259 reviewed
P02763 BXGT005951 Alpha-1-acid glycoprotein 1 5004 reviewed
P02765 BXGT005952 Alpha-2-HS-glycoprotein 197 reviewed Enzyme modulator
P02766 BXGT005953 Transthyretin 7276 reviewed Transporter
P02768 BXGT005955 Serum albumin 213 reviewed Transporter
P02774 BXGT005959 Vitamin D-binding protein 2638 reviewed Transporter
P02787 BXGT005962 Serotransferrin 7018 reviewed Enzyme
P04083 BXGT006147 Annexin A1 301 reviewed
P04637 BXGT006243 Cellular tumor antigen p53 7157 reviewed Transcription factor
P05089 BXGT006310 Arginase-1 383 reviewed Enzyme
P05156 BXGT006329 Complement factor I 3426 reviewed
P05164 BXGT006333 Myeloperoxidase 4353 reviewed Enzyme
P05181 BXGT006337 Cytochrome P450 2E1 1571 reviewed
P05231 BXGT006345 Interleukin-6 3569 reviewed
P05362 BXGT006350 Intercellular adhesion molecule 1 3383 reviewed
P06576 BXGT006454 ATP synthase subunit beta, mitochondrial 506 reviewed Transporter
P06870 BXGT006518 Kallikrein-1 3816 reviewed Enzyme
P07204 BXGT006567 Thrombomodulin 7056 reviewed
P07384 BXGT006619 Calpain-1 catalytic subunit 823 reviewed Enzyme
P07550 BXGT006636 Beta-2 adrenergic receptor 154 reviewed G-protein coupled receptor
P07686 BXGT006657 Beta-hexosaminidase subunit beta 3074 reviewed Enzyme
P08069 BXGT006723 Insulin-like growth factor 1 receptor 3480 reviewed Kinase
P08263 BXGT006759 Glutathione S-transferase A1 2938 reviewed
P08581 BXGT006794 Hepatocyte growth factor receptor 4233 reviewed Kinase
P08603 BXGT006798 Complement factor H 3075 reviewed
P08833 BXGT006827 Insulin-like growth factor-binding protein 1 3484 reviewed Enzyme modulator
P09211 BXGT006869 Glutathione S-transferase P 2950 reviewed
P09601 BXGT006909 Heme oxygenase 1 3162 reviewed
P09917 BXGT006941 Arachidonate 5-lipoxygenase 240 reviewed Enzyme
P10275 BXGT007552 Androgen receptor 367 reviewed Nuclear receptor
P10415 BXGT007567 Apoptosis regulator Bcl-2 596 reviewed Signaling
P10635 BXGT007595 Cytochrome P450 2D6 1565 reviewed
P10909 BXGT007630 Clusterin 1191 reviewed
P11142 BXGT007658 Heat shock cognate 71 kDa protein 3312 reviewed
P11413 BXGT007701 Glucose-6-phosphate 1-dehydrogenase 2539 reviewed Enzyme
P11712 BXGT007738 Cytochrome P450 2C9 1559 reviewed
P12821 BXGT007849 Angiotensin-converting enzyme 1636 reviewed Enzyme
P13716 BXGT007948 Delta-aminolevulinic acid dehydratase 210 reviewed Enzyme
P15529 BXGT008134 Membrane cofactor protein 4179 reviewed
P15559 BXGT008139 NAD(P)H dehydrogenase [quinone] 1 1728 reviewed
P15692 BXGT008147 Vascular endothelial growth factor A 7422 reviewed Signaling
P16070 BXGT008186 CD44 antigen 960 reviewed
P17931 BXGT008356 Galectin-3 3958 reviewed Signaling
P17948 BXGT008358 Vascular endothelial growth factor receptor 1 2321 reviewed Kinase
P19838 BXGT008526 Nuclear factor NF-kappa-B p105 subunit 4790 reviewed Transcription factor
P20062 BXGT008543 Transcobalamin-2 6948 reviewed
P21817 BXGT008693 Ryanodine receptor 1 6261 reviewed Ion channel
P22309 BXGT008753 UDP-glucuronosyltransferase 1-1 54658 reviewed
P24385 BXGT008965 G1/S-specific cyclin-D1 595 reviewed Enzyme modulator
P25105 BXGT009021 Platelet-activating factor receptor 5724 reviewed G-protein coupled receptor
P28161 BXGT009234 Glutathione S-transferase Mu 2 2946 reviewed
P29466 BXGT009349 Caspase-1 834 reviewed Enzyme
P29474 BXGT009352 Nitric oxide synthase, endothelial 4846 reviewed
P29475 BXGT009353 Nitric oxide synthase, brain 4842 reviewed
P30411 BXGT009424 B2 bradykinin receptor 624 reviewed G-protein coupled receptor
P33261 BXGT009707 Cytochrome P450 2C19 1557 reviewed
P34913 BXGT009770 Bifunctional epoxide hydrolase 2 2053 reviewed Enzyme
P35228 BXGT009800 Nitric oxide synthase, inducible 4843 reviewed
P35354 BXGT009816 Prostaglandin G/H synthase 2 5743 reviewed Enzyme
P35408 BXGT009828 Prostaglandin E2 receptor EP4 subtype 5734 reviewed G-protein coupled receptor
P37231 BXGT009972 Peroxisome proliferator-activated receptor gamma 5468 reviewed Nuclear receptor
P37288 BXGT009977 Vasopressin V1a receptor 552 reviewed G-protein coupled receptor
P41235 BXGT010241 Hepatocyte nuclear factor 4-alpha 3172 reviewed Nuclear receptor
P42345 BXGT010304 Serine/threonine-protein kinase mTOR 2475 reviewed Kinase
P42898 BXGT010344 Methylenetetrahydrofolate reductase 4524 reviewed
P43652 BXGT010405 Afamin 173 reviewed Transporter
P46527 BXGT010525 Cyclin-dependent kinase inhibitor 1B 1027 reviewed
P47989 BXGT010602 Xanthine dehydrogenase/oxidase 7498 reviewed Enzyme
P49841 BXGT010750 Glycogen synthase kinase-3 beta 2932 reviewed Kinase
P50440 BXGT010798 Glycine amidinotransferase, mitochondrial 2628 reviewed
P51681 BXGT010878 C-C chemokine receptor type 5 1234 reviewed G-protein coupled receptor
P55789 BXGT011126 FAD-linked sulfhydryl oxidase ALR 2671 reviewed Enzyme
P61769 BXGT011383 Beta-2-microglobulin 567 reviewed Immune response
P69892 BXGT011647 Hemoglobin subunit gamma-2 3048 reviewed
P78540 BXGT011848 Arginase-2, mitochondrial 384 reviewed Enzyme
P80188 BXGT011882 Neutrophil gelatinase-associated lipocalin 3934 reviewed Enzyme
P98164 BXGT012230 Low-density lipoprotein receptor-related protein 2 4036 reviewed
Q07812 BXGT012940 Apoptosis regulator BAX 581 reviewed Signaling
Q07817 BXGT012941 Bcl-2-like protein 1 598 reviewed Signaling
Q13563 BXGT013377 Polycystin-2 5311 reviewed Ion channel
Q13698 BXGT013392 Voltage-dependent L-type calcium channel subunit alpha-1S 779 reviewed Ion channel
Q14393 BXGT013466 Growth arrest-specific protein 6 2621 reviewed Extracellular structure
Q14469 BXGT013473 Transcription factor HES-1 3280 reviewed Transcription factor
Q16236 BXGT013624 Nuclear factor erythroid 2-related factor 2 4780 reviewed Enzyme
Q16665 BXGT013653 Hypoxia-inducible factor 1-alpha 3091 reviewed Transcription factor
Q8IWA4 BXGT018353 Mitofusin-1 55669 reviewed Enzyme
Q92934 BXGT019396 Bcl2-associated agonist of cell death 572 reviewed
Q96D42 BXGT019636 Hepatitis A virus cellular receptor 1 26762 reviewed
Q96EB6 BXGT019646 NAD-dependent protein deacetylase sirtuin-1 23411 reviewed Epigenetic regulator
Q96S37 BXGT019737 Solute carrier family 22 member 12 116085 reviewed Transporter
Q99814 BXGT019965 Endothelial PAS domain-containing protein 1 2034 reviewed Transcription factor
Q9GZT9 BXGT020425 Egl nine homolog 1 54583 reviewed
Q9H6Z9 BXGT020488 Egl nine homolog 3 112399 reviewed
Q9UNN8 BXGT021791 Endothelial protein C receptor 10544 reviewed Enzyme modulator
Q9UQL6 BXGT021813 Histone deacetylase 5 10014 reviewed Epigenetic regulator
Q9Y3D6 BXGT022257 Mitochondrial fission 1 protein 51024 reviewed
P52429 BXGT022667 Diacylglycerol kinase epsilon 8526 reviewed Enzyme
P00738 BXGT022874 Haptoglobin 3240 reviewed Enzyme
Q14258 BXGT024016 E3 ubiquitin/ISG15 ligase TRIM25 7706 reviewed
Q9UKP6 BXGT024239 Urotensin-2 receptor 2837 reviewed G-protein coupled receptor
The  disease-related  compounds
Compounds
BXGC Id Compound Name Structure Molecular Weight Number of targets?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease
The  disease-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compounds in food?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease