Showing entry for Sleep disturbances


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Disease Information
BXGD IdBXGD002689
Disease NameSleep disturbances
Disease CUI IdC0037317
MeSH Codes C10   F03   F01  
Disease Class NameNervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
Semantic TypeSign or Symptom
Human Phenotype Ontology Id HP:0000707  
Human Phenotype Ontology TermAbnormality of the nervous system
Disease Ontology Id   
Disease Ontology Class Name
Disorder Network disorder-protein-compound-food associations
The  disease-related  target proteins
Proteins
Uniport Id BXGT Id Protein Name Gene Status Protein Class
Uniport Id BXGT Id Protein name Gene Status Protein class
F7VJQ1 BXGT003310 Alternative prion protein 5621 reviewed
O14936 BXGT004114 Peripheral plasma membrane protein CASK 8573 reviewed Kinase
O14980 BXGT004119 Exportin-1 7514 reviewed Receptor
O43612 BXGT004605 Orexin 3060 reviewed
O43614 BXGT004606 Orexin receptor type 2 3062 reviewed G-protein coupled receptor
O43766 BXGT004622 Lipoyl synthase, mitochondrial 11019 reviewed
O75475 BXGT005130 PC4 and SFRS1-interacting protein 11168 reviewed Signaling
O75628 BXGT005140 GTP-binding protein REM 1 28954 reviewed
O75899 BXGT005161 Gamma-aminobutyric acid type B receptor subunit 2 9568 reviewed G-protein coupled receptor
O76039 BXGT005171 Cyclin-dependent kinase-like 5 6792 reviewed Kinase
O95278 BXGT005370 Laforin 7957 reviewed
O95831 BXGT005399 Apoptosis-inducing factor 1, mitochondrial 9131 reviewed Enzyme
P00326 BXGT005499 Alcohol dehydrogenase 1C 126 reviewed Enzyme
P00797 BXGT005658 Renin 5972 reviewed Enzyme
P00915 BXGT005689 Carbonic anhydrase 1 759 reviewed
P01034 BXGT005721 Cystatin-C 1471 reviewed
P01236 BXGT005744 Prolactin 5617 reviewed Signaling
P01375 BXGT005753 Tumor necrosis factor 7124 reviewed Signaling
P01584 BXGT005772 Interleukin-1 beta 3553 reviewed
P01920 BXGT005817 HLA class II histocompatibility antigen, DQ beta 1 chain 3119 reviewed Immune response
P02545 BXGT005889 Prelamin-A/C 4000 reviewed
P02649 BXGT005909 Apolipoprotein E 348 reviewed
P02741 BXGT005936 C-reactive protein 1401 reviewed
P02774 BXGT005959 Vitamin D-binding protein 2638 reviewed Transporter
P03372 BXGT006059 Estrogen receptor 2099 reviewed Nuclear receptor
P04062 BXGT006140 Lysosomal acid glucosylceramidase 2629 reviewed
P04150 BXGT006154 Glucocorticoid receptor 2908 reviewed Nuclear receptor
P04156 BXGT006156 Major prion protein 5621 reviewed
P05091 BXGT006312 Aldehyde dehydrogenase, mitochondrial 217 reviewed Enzyme
P05231 BXGT006345 Interleukin-6 3569 reviewed
P06276 BXGT006430 Cholinesterase 590 reviewed
P07333 BXGT006602 Macrophage colony-stimulating factor 1 receptor 1436 reviewed Kinase
P09172 BXGT006865 Dopamine beta-hydroxylase 1621 reviewed
P10070 BXGT007534 Zinc finger protein GLI2 2736 reviewed
P10636 BXGT007596 Microtubule-associated protein tau 4137 reviewed
P10827 BXGT007623 Thyroid hormone receptor alpha 7067 reviewed Nuclear receptor
P10828 BXGT007624 Thyroid hormone receptor beta 7068 reviewed Nuclear receptor
P11166 BXGT007661 Solute carrier family 2, facilitated glucose transporter member 1 6513 reviewed Transporter
P11362 BXGT007693 Fibroblast growth factor receptor 1 2260 reviewed Kinase
P12821 BXGT007849 Angiotensin-converting enzyme 1636 reviewed Enzyme
P15311 BXGT008106 Ezrin 7430 reviewed Cellular structure
P15692 BXGT008147 Vascular endothelial growth factor A 7422 reviewed Signaling
P16473 BXGT008234 Thyrotropin receptor 7253 reviewed G-protein coupled receptor
P17948 BXGT008358 Vascular endothelial growth factor receptor 1 2321 reviewed Kinase
P19113 BXGT008458 Histidine decarboxylase 3067 reviewed
P20711 BXGT008594 Aromatic-L-amino-acid decarboxylase 1644 reviewed
P20807 BXGT008601 Calpain-3 825 reviewed Enzyme
P20930 BXGT008616 Filaggrin 2312 reviewed Cellular structure
P20933 BXGT008618 N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase 175 reviewed Enzyme
P21397 BXGT008644 Amine oxidase [flavin-containing] A 4128 reviewed
P21728 BXGT008686 D(1A) dopamine receptor 1812 reviewed G-protein coupled receptor
P21917 BXGT008707 D(4) dopamine receptor 1815 reviewed G-protein coupled receptor
P21964 BXGT008714 Catechol O-methyltransferase 1312 reviewed Enzyme
P22303 BXGT008751 Acetylcholinesterase 43 reviewed Enzyme
P22304 BXGT008752 Iduronate 2-sulfatase 3423 reviewed
P23415 BXGT008864 Glycine receptor subunit alpha-1 2741 reviewed Ion channel
P23560 BXGT008883 Brain-derived neurotrophic factor 627 reviewed Signaling
P25440 BXGT009044 Bromodomain-containing protein 2 6046 reviewed Epigenetic regulator
P30793 BXGT009466 GTP cyclohydrolase 1 2643 reviewed Enzyme
P31645 BXGT009558 Sodium-dependent serotonin transporter 6532 reviewed Transporter
P35222 BXGT009799 Catenin beta-1 1499 reviewed
P35270 BXGT009807 Sepiapterin reductase 6697 reviewed
P35462 BXGT009835 D(3) dopamine receptor 1814 reviewed G-protein coupled receptor
P35475 BXGT009837 Alpha-L-iduronidase 3425 reviewed Enzyme
P35498 BXGT009838 Sodium channel protein type 1 subunit alpha 6323 reviewed Ion channel
P35869 BXGT009877 Aryl hydrocarbon receptor 196 reviewed Transcription factor
P37288 BXGT009977 Vasopressin V1a receptor 552 reviewed G-protein coupled receptor
P37840 BXGT010015 Alpha-synuclein 6622 reviewed Transporter
P42263 BXGT010295 Glutamate receptor 3 2892 reviewed Ion channel
P42345 BXGT010304 Serine/threonine-protein kinase mTOR 2475 reviewed Kinase
P43354 BXGT010381 Nuclear receptor subfamily 4 group A member 2 4929 reviewed Nuclear receptor
P45381 BXGT010460 Aspartoacylase 443 reviewed
P48167 BXGT010621 Glycine receptor subunit beta 2743 reviewed Ion channel
P49286 BXGT010691 Melatonin receptor type 1B 4544 reviewed G-protein coupled receptor
P49448 BXGT010709 Glutamate dehydrogenase 2, mitochondrial 2747 reviewed Enzyme
P49591 BXGT010715 Serine--tRNA ligase, cytoplasmic 6301 reviewed Enzyme
P50135 BXGT010776 Histamine N-methyltransferase 3176 reviewed
P50897 BXGT010823 Palmitoyl-protein thioesterase 1 5538 reviewed Enzyme
P51688 BXGT010883 N-sulphoglucosamine sulphohydrolase 6448 reviewed Enzyme
P51812 BXGT010893 Ribosomal protein S6 kinase alpha-3 6197 reviewed Kinase
P54802 BXGT011081 Alpha-N-acetylglucosaminidase 4669 reviewed
P56524 BXGT011176 Histone deacetylase 4 9759 reviewed Epigenetic regulator
P56537 BXGT011177 Eukaryotic translation initiation factor 6 3692 reviewed Nucleic acid binding
P57059 BXGT011210 Serine/threonine-protein kinase SIK1 150094 reviewed
P60174 BXGT011294 Triosephosphate isomerase 7167 reviewed Enzyme
P98164 BXGT012230 Low-density lipoprotein receptor-related protein 2 4036 reviewed
Q00604 BXGT012538 Norrin 4693 reviewed
Q00653 BXGT012541 Nuclear factor NF-kappa-B p100 subunit 4791 reviewed Transcription factor
Q01959 BXGT012624 Sodium-dependent dopamine transporter 6531 reviewed Transporter
Q03164 BXGT012700 Histone-lysine N-methyltransferase 2A 4297 reviewed
Q04637 BXGT012771 Eukaryotic translation initiation factor 4 gamma 1 1981 reviewed Nucleic acid binding
Q05940 BXGT012846 Synaptic vesicular amine transporter 6571 reviewed Transporter
Q06710 BXGT012887 Paired box protein Pax-8 7849 reviewed
Q06787 BXGT012890 Synaptic functional regulator FMR1 2332 reviewed Nucleic acid binding
Q09470 BXGT013037 Potassium voltage-gated channel subfamily A member 1 3736 reviewed Ion channel
Q11203 BXGT013218 CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase 6487 reviewed
Q12830 BXGT013268 Nucleosome-remodeling factor subunit BPTF 2186 reviewed
Q13002 BXGT013303 Glutamate receptor ionotropic, kainate 2 2898 reviewed Ion channel
Q13554 BXGT013374 Calcium/calmodulin-dependent protein kinase type II subunit beta 816 reviewed Kinase
Q13936 BXGT013404 Voltage-dependent L-type calcium channel subunit alpha-1C 775 reviewed Ion channel
Q14004 BXGT013435 Cyclin-dependent kinase 13 8621 reviewed Kinase
Q14203 BXGT013455 Dynactin subunit 1 1639 reviewed Chaperone
Q14204 BXGT013456 Cytoplasmic dynein 1 heavy chain 1 1778 reviewed Enzyme
Q14654 BXGT013495 ATP-sensitive inward rectifier potassium channel 11 3767 reviewed Ion channel
Q14683 BXGT013500 Structural maintenance of chromosomes protein 1A 8243 reviewed
Q5S007 BXGT015650 Leucine-rich repeat serine/threonine-protein kinase 2 120892 reviewed Kinase
Q5Y7D3 BXGT015912 HLA class II histocompatibility antigen DQ beta chain 3119 unreviewed
Q6NVY1 BXGT016432 3-hydroxyisobutyryl-CoA hydrolase, mitochondrial 26275 reviewed Enzyme
Q86TM3 BXGT017607 Probable ATP-dependent RNA helicase DDX53 168400 reviewed
Q8IVA8 BXGT018342 Glutamate decarboxylase 1 (Brain, 67kDa) 2571 unreviewed
Q8WWQ0 BXGT019003 PH-interacting protein 55023 reviewed Epigenetic regulator
Q92993 BXGT019403 Histone acetyltransferase KAT5 10524 reviewed
Q93009 BXGT019455 Ubiquitin carboxyl-terminal hydrolase 7 7874 reviewed Enzyme
Q96D42 BXGT019636 Hepatitis A virus cellular receptor 1 26762 reviewed
Q96EN8 BXGT019649 Molybdenum cofactor sulfurase 55034 reviewed
Q96QK1 BXGT019720 Vacuolar protein sorting-associated protein 35 55737 reviewed Transporter
Q96SW2 BXGT019743 Protein cereblon 51185 reviewed Enzyme
Q96T60 BXGT019745 Bifunctional polynucleotide phosphatase/kinase 11284 reviewed
Q99250 BXGT019913 Sodium channel protein type 2 subunit alpha 6326 reviewed Ion channel
Q99259 BXGT019915 Glutamate decarboxylase 1 2571 reviewed Enzyme
Q99572 BXGT019935 P2X purinoceptor 7 5027 reviewed Ion channel
Q99700 BXGT019949 Ataxin-2 6311 reviewed Nucleic acid binding
Q99808 BXGT019964 Equilibrative nucleoside transporter 1 2030 reviewed Transporter
Q9BXJ9 BXGT020170 N-alpha-acetyltransferase 15, NatA auxiliary subunit 80155 reviewed Enzyme
Q9BY41 BXGT020180 Histone deacetylase 8 55869 reviewed Epigenetic regulator
Q9H251 BXGT020449 Cadherin-23 64072 reviewed
Q9H9B1 BXGT020501 Histone-lysine N-methyltransferase EHMT1 79813 reviewed Epigenetic regulator
Q9HD40 BXGT020542 O-phosphoseryl-tRNA(Sec) selenium transferase 51091 reviewed
Q9NQX3 BXGT021172 Gephyrin 10243 reviewed
Q9UGL1 BXGT021685 Lysine-specific demethylase 5B 10765 reviewed Epigenetic regulator
Q9UGM6 BXGT021687 Tryptophan--tRNA ligase, mitochondrial 10352 reviewed
Q9UHD8 BXGT021698 Septin-9 10801 reviewed Enzyme modulator
Q9UKE5 BXGT021741 TRAF2 and NCK-interacting protein kinase 23043 reviewed Kinase
Q9UKM7 BXGT021747 Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase 11253 reviewed Chaperone
Q9UQD0 BXGT021811 Sodium channel protein type 8 subunit alpha 6334 reviewed Ion channel
Q9Y3I1 BXGT022260 F-box only protein 7 25793 reviewed
Q96C86 BXGT022803 m7GpppX diphosphatase 28960 reviewed Enzyme
Q9UNS1 BXGT022882 Protein timeless homolog 8914 reviewed
A6NGN9 BXGT023893 IgLON family member 5 402665 reviewed
P51608 BXGT025073 Methyl-CpG-binding protein 2 4204 reviewed Epigenetic regulator
Q9UQE7 BXGT025899 Structural maintenance of chromosomes protein 3 9126 reviewed
P09471 BXGT026153 Guanine nucleotide-binding protein G(o) subunit alpha 2775 reviewed Enzyme modulator
The  disease-related  compounds
Compounds
BXGC Id Compound Name Structure Molecular Weight Number of targets?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease
The  disease-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compounds in food?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease