Showing entry for Heart Decompensation


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Disease Information
BXGD IdBXGD016674
Disease NameHeart Decompensation
Disease CUI IdC1961112
MeSH Codes C14  
Disease Class NameCardiovascular Diseases
Semantic TypePathologic Function
Human Phenotype Ontology Id   
Human Phenotype Ontology Term
Disease Ontology Id   
Disease Ontology Class Name
Disorder Network disorder-protein-compound-food associations
The  disease-related  target proteins
Proteins
Uniport Id BXGT Id Protein Name Gene Status Protein Class
Uniport Id BXGT Id Protein name Gene Status Protein class
O00767 BXGT003949 Acyl-CoA desaturase 6319 reviewed
O14733 BXGT004087 Dual specificity mitogen-activated protein kinase kinase 7 5609 reviewed Kinase
O15530 BXGT004177 3-phosphoinositide-dependent protein kinase 1 5170 reviewed Kinase
O60603 BXGT004887 Toll-like receptor 2 7097 reviewed
O75116 BXGT005100 Rho-associated protein kinase 2 9475 reviewed Kinase
O75390 BXGT005123 Citrate synthase, mitochondrial 1431 reviewed Enzyme
P00441 BXGT005540 Superoxide dismutase [Cu-Zn] 6647 reviewed Enzyme
P00746 BXGT005638 Complement factor D 1675 reviewed Enzyme
P00750 BXGT005642 Tissue-type plasminogen activator 5327 reviewed Enzyme
P00797 BXGT005658 Renin 5972 reviewed Enzyme
P01019 BXGT005717 Angiotensinogen 183 reviewed Enzyme modulator
P01189 BXGT005742 Pro-opiomelanocortin 5443 reviewed
P01236 BXGT005744 Prolactin 5617 reviewed Signaling
P01270 BXGT005746 Parathyroid hormone 5741 reviewed
P01275 BXGT005747 Glucagon 2641 reviewed
P01308 BXGT005749 Insulin 3630 reviewed
P01375 BXGT005753 Tumor necrosis factor 7124 reviewed Signaling
P01579 BXGT005770 Interferon gamma 3458 reviewed
P01584 BXGT005772 Interleukin-1 beta 3553 reviewed
P02654 BXGT005911 Apolipoprotein C-I 341 reviewed
P02741 BXGT005936 C-reactive protein 1401 reviewed
P02743 BXGT005937 Serum amyloid P-component 325 reviewed
P02753 BXGT005945 Retinol-binding protein 4 5950 reviewed Transporter
P02768 BXGT005955 Serum albumin 213 reviewed Transporter
P04040 BXGT006132 Catalase 847 reviewed Enzyme
P04179 BXGT006163 Superoxide dismutase [Mn], mitochondrial 6648 reviewed Enzyme
P04275 BXGT006180 von Willebrand factor 7450 reviewed Enzyme modulator
P04637 BXGT006243 Cellular tumor antigen p53 7157 reviewed Transcription factor
P04792 BXGT006264 Heat shock protein beta-1 3315 reviewed
P04839 BXGT006273 Cytochrome b-245 heavy chain 1536 reviewed Ion channel
P05121 BXGT006320 Plasminogen activator inhibitor 1 5054 reviewed Enzyme modulator
P05231 BXGT006345 Interleukin-6 3569 reviewed
P05556 BXGT006368 Integrin beta-1 3688 reviewed Receptor
P07437 BXGT006624 Tubulin beta chain 203068 reviewed Cellular structure
P08235 BXGT006751 Mineralocorticoid receptor 4306 reviewed Nuclear receptor
P08588 BXGT006795 Beta-1 adrenergic receptor 153 reviewed G-protein coupled receptor
P09601 BXGT006909 Heme oxygenase 1 3162 reviewed
P10145 BXGT007542 Interleukin-8 3576 reviewed Signaling
P12821 BXGT007849 Angiotensin-converting enzyme 1636 reviewed Enzyme
P13500 BXGT007916 C-C motif chemokine 2 6347 reviewed Signaling
P13637 BXGT007933 Sodium/potassium-transporting ATPase subunit alpha-3 478 reviewed Transporter
P13945 BXGT007972 Beta-3 adrenergic receptor 155 reviewed G-protein coupled receptor
P15692 BXGT008147 Vascular endothelial growth factor A 7422 reviewed Signaling
P16066 BXGT008185 Atrial natriuretic peptide receptor 1 4881 reviewed Kinase
P16234 BXGT008209 Platelet-derived growth factor receptor alpha 5156 reviewed Kinase
P18825 BXGT008426 Alpha-2C adrenergic receptor 152 reviewed G-protein coupled receptor
P19438 BXGT008480 Tumor necrosis factor receptor superfamily member 1A 7132 reviewed
P19634 BXGT008504 Sodium/hydrogen exchanger 1 6548 reviewed Transporter
P23219 BXGT008837 Prostaglandin G/H synthase 1 5742 reviewed Enzyme
P24530 BXGT008975 Endothelin receptor type B 1910 reviewed G-protein coupled receptor
P25098 BXGT009015 Beta-adrenergic receptor kinase 1 156 reviewed Kinase
P25101 BXGT009018 Endothelin-1 receptor 1909 reviewed G-protein coupled receptor
P27169 BXGT009161 Serum paraoxonase/arylesterase 1 5444 reviewed
P29474 BXGT009352 Nitric oxide synthase, endothelial 4846 reviewed
P30086 BXGT009400 Phosphatidylethanolamine-binding protein 1 5037 reviewed Enzyme modulator
P30518 BXGT009428 Vasopressin V2 receptor 554 reviewed G-protein coupled receptor
P30556 BXGT009441 Type-1 angiotensin II receptor 185 reviewed G-protein coupled receptor
P31323 BXGT009521 cAMP-dependent protein kinase type II-beta regulatory subunit 5577 reviewed
P34913 BXGT009770 Bifunctional epoxide hydrolase 2 2053 reviewed Enzyme
P35228 BXGT009800 Nitric oxide synthase, inducible 4843 reviewed
P35354 BXGT009816 Prostaglandin G/H synthase 2 5743 reviewed Enzyme
P35558 BXGT009847 Phosphoenolpyruvate carboxykinase, cytosolic [GTP] 5105 reviewed Kinase
P36969 BXGT009949 Phospholipid hydroperoxide glutathione peroxidase 2879 reviewed Enzyme
P37231 BXGT009972 Peroxisome proliferator-activated receptor gamma 5468 reviewed Nuclear receptor
P41595 BXGT010267 5-hydroxytryptamine receptor 2B 3357 reviewed G-protein coupled receptor
P45379 BXGT010459 Troponin T, cardiac muscle 7139 reviewed Cellular structure
P47989 BXGT010602 Xanthine dehydrogenase/oxidase 7498 reviewed Enzyme
P48736 BXGT010658 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform 5294 reviewed Kinase
P49327 BXGT010694 Fatty acid synthase 2194 reviewed Enzyme
P49841 BXGT010750 Glycogen synthase kinase-3 beta 2932 reviewed Kinase
P50440 BXGT010798 Glycine amidinotransferase, mitochondrial 2628 reviewed
P53396 BXGT010988 ATP-citrate synthase 47 reviewed Enzyme
P60981 BXGT011344 Destrin 11034 reviewed
P63000 BXGT011481 Ras-related C3 botulinum toxin substrate 1 5879 reviewed Enzyme modulator
P78380 BXGT011841 Oxidized low-density lipoprotein receptor 1 4973 reviewed
Q13085 BXGT013309 Acetyl-CoA carboxylase 1 31 reviewed
Q15848 BXGT013609 Adiponectin 9370 reviewed
Q16236 BXGT013624 Nuclear factor erythroid 2-related factor 2 4780 reviewed Enzyme
Q16665 BXGT013653 Hypoxia-inducible factor 1-alpha 3091 reviewed Transcription factor
Q96EB6 BXGT019646 NAD-dependent protein deacetylase sirtuin-1 23411 reviewed Epigenetic regulator
Q9H7Z6 BXGT020493 Histone acetyltransferase KAT8 84148 reviewed
Q9NPH5 BXGT021159 NADPH oxidase 4 50507 reviewed Enzyme
Q9Y5S8 BXGT022302 NADPH oxidase 1 27035 reviewed
O14793 BXGT023280 Growth/differentiation factor 8 2660 reviewed Signaling
P19875 BXGT023294 C-X-C motif chemokine 2 2920 reviewed Signaling
P16615 BXGT023653 Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 488 reviewed Transporter
The  disease-related  compounds
Compounds
BXGC Id Compound Name Structure Molecular Weight Number of targets?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease
The  disease-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compounds in food?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease