Showing entry for Glomerulosclerosis (disorder)


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Disease Information
BXGD IdBXGD004032
Disease NameGlomerulosclerosis (disorder)
Disease CUI IdC0178664
MeSH Codes C13   C12   C14  
Disease Class NameFemale Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases; Cardiovascular Diseases
Semantic TypeDisease or Syndrome
Human Phenotype Ontology Id HP:0000119  
Human Phenotype Ontology TermAbnormality of the genitourinary system
Disease Ontology Id   
Disease Ontology Class Name
Disorder Network disorder-protein-compound-food associations
The  disease-related  target proteins
Proteins
Uniport Id BXGT Id Protein Name Gene Status Protein Class
Uniport Id BXGT Id Protein name Gene Status Protein class
O14786 BXGT004099 Neuropilin-1 8829 reviewed
O14791 BXGT004101 Apolipoprotein L1 8542 reviewed Transporter
O15119 BXGT004128 T-box transcription factor TBX3 6926 reviewed Transcription factor
O15123 BXGT004130 Angiopoietin-2 285 reviewed Signaling
O15553 BXGT004181 Pyrin 4210 reviewed
O43707 BXGT004616 Alpha-actinin-4 81 reviewed
O75469 BXGT005128 Nuclear receptor subfamily 1 group I member 2 8856 reviewed Nuclear receptor
P00747 BXGT005639 Plasminogen 5340 reviewed Enzyme
P00797 BXGT005658 Renin 5972 reviewed Enzyme
P01019 BXGT005717 Angiotensinogen 183 reviewed Enzyme modulator
P01024 BXGT005719 Complement C3 718 reviewed Enzyme modulator
P01137 BXGT005737 Transforming growth factor beta-1 proprotein 7040 reviewed Signaling
P01375 BXGT005753 Tumor necrosis factor 7124 reviewed Signaling
P01584 BXGT005772 Interleukin-1 beta 3553 reviewed
P02461 BXGT005880 Collagen alpha-1(III) chain 1281 reviewed
P02649 BXGT005909 Apolipoprotein E 348 reviewed
P02652 BXGT005910 Apolipoprotein A-II 336 reviewed Transporter
P02654 BXGT005911 Apolipoprotein C-I 341 reviewed
P02751 BXGT005943 Fibronectin 2335 reviewed Signaling
P02768 BXGT005955 Serum albumin 213 reviewed Transporter
P03956 BXGT006120 Interstitial collagenase 4312 reviewed Enzyme
P04179 BXGT006163 Superoxide dismutase [Mn], mitochondrial 6648 reviewed Enzyme
P04180 BXGT006164 Phosphatidylcholine-sterol acyltransferase 3931 reviewed Enzyme
P05109 BXGT006318 Protein S100-A8 6279 reviewed Calcium-binding protein
P05120 BXGT006319 Plasminogen activator inhibitor 2 5055 reviewed Enzyme modulator
P05121 BXGT006320 Plasminogen activator inhibitor 1 5054 reviewed Enzyme modulator
P05164 BXGT006333 Myeloperoxidase 4353 reviewed Enzyme
P05231 BXGT006345 Interleukin-6 3569 reviewed
P05362 BXGT006350 Intercellular adhesion molecule 1 3383 reviewed
P05771 BXGT006384 Protein kinase C beta type 5579 reviewed Kinase
P06870 BXGT006518 Kallikrein-1 3816 reviewed Enzyme
P07203 BXGT006566 Glutathione peroxidase 1 2876 reviewed Enzyme
P07949 BXGT006703 Proto-oncogene tyrosine-protein kinase receptor Ret 5979 reviewed Kinase
P08253 BXGT006757 72 kDa type IV collagenase 4313 reviewed Enzyme
P08670 BXGT006810 Vimentin 7431 reviewed
P08833 BXGT006827 Insulin-like growth factor-binding protein 1 3484 reviewed Enzyme modulator
P08922 BXGT006843 Proto-oncogene tyrosine-protein kinase ROS 6098 reviewed Kinase
P09237 BXGT006874 Matrilysin 4316 reviewed Enzyme
P10276 BXGT007553 Retinoic acid receptor alpha 5914 reviewed Nuclear receptor
P10415 BXGT007567 Apoptosis regulator Bcl-2 596 reviewed Signaling
P10909 BXGT007630 Clusterin 1191 reviewed
P11166 BXGT007661 Solute carrier family 2, facilitated glucose transporter member 1 6513 reviewed Transporter
P11226 BXGT007675 Mannose-binding protein C 4153 reviewed Receptor
P12821 BXGT007849 Angiotensin-converting enzyme 1636 reviewed Enzyme
P13500 BXGT007916 C-C motif chemokine 2 6347 reviewed Signaling
P14210 BXGT007994 Hepatocyte growth factor 3082 reviewed Enzyme
P14780 BXGT008053 Matrix metalloproteinase-9 4318 reviewed Enzyme
P15692 BXGT008147 Vascular endothelial growth factor A 7422 reviewed Signaling
P15941 BXGT008176 Mucin-1 4582 reviewed
P16070 BXGT008186 CD44 antigen 960 reviewed
P16144 BXGT008200 Integrin beta-4 3691 reviewed Receptor
P16930 BXGT008272 Fumarylacetoacetase 2184 reviewed
P17252 BXGT008294 Protein kinase C alpha type 5578 reviewed Kinase
P18075 BXGT008375 Bone morphogenetic protein 7 655 reviewed Signaling
P19544 BXGT008494 Wilms tumor protein 7490 reviewed Nucleic acid binding
P22004 BXGT008718 Bone morphogenetic protein 6 654 reviewed Signaling
P26447 BXGT009114 Protein S100-A4 6275 reviewed Calcium-binding protein
P27361 BXGT009176 Mitogen-activated protein kinase 3 5595 reviewed Kinase
P28482 BXGT009263 Mitogen-activated protein kinase 1 5594 reviewed Kinase
P29400 BXGT009343 Collagen alpha-5(IV) chain 1287 reviewed
P29965 BXGT009388 CD40 ligand 959 reviewed Signaling
P30556 BXGT009441 Type-1 angiotensin II receptor 185 reviewed G-protein coupled receptor
P31040 BXGT009503 Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial 6389 reviewed Enzyme
P31639 BXGT009556 Sodium/glucose cotransporter 2 6524 reviewed Transporter
P31751 BXGT009576 RAC-beta serine/threonine-protein kinase 208 reviewed Kinase
P35228 BXGT009800 Nitric oxide synthase, inducible 4843 reviewed
P35354 BXGT009816 Prostaglandin G/H synthase 2 5743 reviewed Enzyme
P35579 BXGT009852 Myosin-9 4627 reviewed
P35968 BXGT009887 Vascular endothelial growth factor receptor 2 3791 reviewed Kinase
P36897 BXGT009941 TGF-beta receptor type-1 7046 reviewed Kinase
P37231 BXGT009972 Peroxisome proliferator-activated receptor gamma 5468 reviewed Nuclear receptor
P40337 BXGT010174 von Hippel-Lindau disease tumor suppressor 7428 reviewed Enzyme
P40926 BXGT010207 Malate dehydrogenase, mitochondrial 4191 reviewed Enzyme
P41597 BXGT010268 C-C chemokine receptor type 2 729230 reviewed
P42226 BXGT010288 Signal transducer and activator of transcription 6 6778 reviewed Nucleic acid binding
P42345 BXGT010304 Serine/threonine-protein kinase mTOR 2475 reviewed Kinase
P45452 BXGT010462 Collagenase 3 4322 reviewed Enzyme
P46108 BXGT010509 Adapter molecule crk 1398 reviewed
P46527 BXGT010525 Cyclin-dependent kinase inhibitor 1B 1027 reviewed
P46531 BXGT010526 Neurogenic locus notch homolog protein 1 4851 reviewed
P48061 BXGT010616 Stromal cell-derived factor 1 6387 reviewed
P48357 BXGT010627 Leptin receptor 3953 reviewed Signaling
P49327 BXGT010694 Fatty acid synthase 2194 reviewed Enzyme
P50052 BXGT010768 Type-2 angiotensin II receptor 186 reviewed G-protein coupled receptor
P51795 BXGT010891 H(+)/Cl(-) exchange transporter 5 1184 reviewed Ion channel
P53396 BXGT010988 ATP-citrate synthase 47 reviewed Enzyme
P54802 BXGT011081 Alpha-N-acetylglucosaminidase 4669 reviewed
P55085 BXGT011104 Proteinase-activated receptor 2 2150 reviewed G-protein coupled receptor
P55211 BXGT011111 Caspase-9 842 reviewed Enzyme
P60709 BXGT011322 Actin, cytoplasmic 1 60 reviewed Cellular structure
P61073 BXGT011352 C-X-C chemokine receptor type 4 7852 reviewed G-protein coupled receptor
P61224 BXGT011370 Ras-related protein Rap-1b 5908 reviewed Enzyme modulator
P63000 BXGT011481 Ras-related C3 botulinum toxin substrate 1 5879 reviewed Enzyme modulator
P78380 BXGT011841 Oxidized low-density lipoprotein receptor 1 4973 reviewed
P80188 BXGT011882 Neutrophil gelatinase-associated lipocalin 3934 reviewed Enzyme
P84022 BXGT012027 Mothers against decapentaplegic homolog 3 4088 reviewed Transcription factor
Q01118 BXGT012570 Sodium channel protein type 7 subunit alpha 6332 reviewed Ion channel
Q07075 BXGT012917 Glutamyl aminopeptidase 2028 reviewed Enzyme
Q07157 BXGT012920 Tight junction protein ZO-1 7082 reviewed Cell-cell junction
Q07889 BXGT012946 Son of sevenless homolog 1 6654 reviewed Enzyme modulator
Q09428 BXGT013036 ATP-binding cassette sub-family C member 8 6833 reviewed Transporter
Q13155 BXGT013320 Aminoacyl tRNA synthase complex-interacting multifunctional protein 2 7965 reviewed
Q13547 BXGT013373 Histone deacetylase 1 3065 reviewed Epigenetic regulator
Q14108 BXGT013440 Lysosome membrane protein 2 950 reviewed Receptor
Q14116 BXGT013442 Interleukin-18 3606 reviewed
Q15149 BXGT013547 Plectin 5339 reviewed Cellular structure
Q16539 BXGT013634 Mitogen-activated protein kinase 14 1432 reviewed Kinase
Q16665 BXGT013653 Hypoxia-inducible factor 1-alpha 3091 reviewed Transcription factor
Q86VQ6 BXGT017620 Thioredoxin reductase 3 114112 reviewed Enzyme
Q8WXF7 BXGT019011 Atlastin-1 51062 reviewed Enzyme modulator
Q92769 BXGT019370 Histone deacetylase 2 3066 reviewed Epigenetic regulator
Q96D42 BXGT019636 Hepatitis A virus cellular receptor 1 26762 reviewed
Q96EB6 BXGT019646 NAD-dependent protein deacetylase sirtuin-1 23411 reviewed Epigenetic regulator
Q96J66 BXGT019680 ATP-binding cassette sub-family C member 11 85320 reviewed Transporter
Q96P20 BXGT019704 NACHT, LRR and PYD domains-containing protein 3 114548 reviewed
Q96QV1 BXGT019722 Hedgehog-interacting protein 64399 reviewed
Q96S44 BXGT019738 EKC/KEOPS complex subunit TP53RK 112858 reviewed Kinase
Q99828 BXGT019967 Calcium and integrin-binding protein 1 10519 reviewed
Q99972 BXGT019979 Myocilin 4653 reviewed Cellular structure
Q9BYF1 BXGT020186 Angiotensin-converting enzyme 2 59272 reviewed Enzyme
Q9NPH2 BXGT021158 Inositol-3-phosphate synthase 1 51477 reviewed
Q9NZL9 BXGT021277 Methionine adenosyltransferase 2 subunit beta 27430 reviewed
Q9UKV0 BXGT021750 Histone deacetylase 9 9734 reviewed Epigenetic regulator
Q9Y275 BXGT022223 Tumor necrosis factor ligand superfamily member 13B 10673 reviewed
Q9Y4K0 BXGT022280 Lysyl oxidase homolog 2 4017 reviewed
P35232 BXGT022663 Prohibitin 5245 reviewed
Q01995 BXGT022678 Transgelin 6876 reviewed Cellular structure
O60502 BXGT023392 Protein O-GlcNAcase 10724 reviewed
Q16552 BXGT023419 Interleukin-17A 3605 reviewed
P07954 BXGT023939 Fumarate hydratase, mitochondrial 2271 reviewed Enzyme
Q14657 BXGT024111 EKC/KEOPS complex subunit LAGE3 8270 reviewed
Q9NPF4 BXGT024113 Probable tRNA N6-adenosine threonylcarbamoyltransferase 55644 reviewed Enzyme
P08123 BXGT024477 Collagen alpha-2(I) chain 1278 reviewed
Q9NRR4 BXGT025788 Ribonuclease 3 29102 reviewed Enzyme
The  disease-related  compounds
Compounds
BXGC Id Compound Name Structure Molecular Weight Number of targets?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease
The  disease-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compounds in food?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease