adisease

Showing entry for Linear atrophy

General Disease Information
BXGD Id	BXGD003600
Disease Name	Linear atrophy
Disease CUI Id	C0152459
MeSH Codes	C23
Disease Class Name	Pathological Conditions, Signs and Symptoms
Semantic Type	Acquired Abnormality
Human Phenotype Ontology Id	HP:0001574
Human Phenotype Ontology Term	Abnormality of the integument
Disease Ontology Id
Disease Ontology Class Name
Disorder Network	disorder-protein-compound-food associations

The disease-related target proteins

Proteins

Uniport Id	BXGT Id	Protein Name	Gene	Status	Protein Class
Uniport Id	BXGT Id	Protein name	Gene	Status	Protein class
O00222	BXGT003899	Metabotropic glutamate receptor 8	2918	reviewed	G-protein coupled receptor
O14786	BXGT004099	Neuropilin-1	8829	reviewed
O15075	BXGT004124	Serine/threonine-protein kinase DCLK1	9201	reviewed	Kinase
O15244	BXGT004140	Solute carrier family 22 member 2	6582	reviewed	Transporter
O60494	BXGT004879	Cubilin	8029	reviewed
O75030	BXGT005096	Microphthalmia-associated transcription factor	4286	reviewed
O95255	BXGT005363	Multidrug resistance-associated protein 6	368	reviewed	Transporter
O95263	BXGT005366	High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B	8622	reviewed
P01100	BXGT005727	Proto-oncogene c-Fos	2353	reviewed	Transcription factor
P01133	BXGT005736	Pro-epidermal growth factor	1950	reviewed
P01189	BXGT005742	Pro-opiomelanocortin	5443	reviewed
P01275	BXGT005747	Glucagon	2641	reviewed
P01303	BXGT005748	Pro-neuropeptide Y	4852	reviewed	Signaling
P01375	BXGT005753	Tumor necrosis factor	7124	reviewed	Signaling
P02452	BXGT005878	Collagen alpha-1(I) chain	1277	reviewed
P02458	BXGT005879	Collagen alpha-1(II) chain	1280	reviewed
P02751	BXGT005943	Fibronectin	2335	reviewed	Signaling
P03372	BXGT006059	Estrogen receptor	2099	reviewed	Nuclear receptor
P04150	BXGT006154	Glucocorticoid receptor	2908	reviewed	Nuclear receptor
P04271	BXGT006177	Protein S100-B	6285	reviewed	Calcium-binding protein
P04637	BXGT006243	Cellular tumor antigen p53	7157	reviewed	Transcription factor
P05937	BXGT006396	Calbindin	793	reviewed	Calcium-binding protein
P06401	BXGT006436	Progesterone receptor	5241	reviewed	Nuclear receptor
P06850	BXGT006511	Corticoliberin	1392	reviewed	Signaling
P07101	BXGT006547	Tyrosine 3-monooxygenase	7054	reviewed
P08034	BXGT006716	Gap junction beta-1 protein	2705	reviewed	Cell-cell junction
P08253	BXGT006757	72 kDa type IV collagenase	4313	reviewed	Enzyme
P08254	BXGT006758	Stromelysin-1	4314	reviewed	Enzyme
P09874	BXGT006934	Poly [ADP-ribose] polymerase 1	142	reviewed
P10275	BXGT007552	Androgen receptor	367	reviewed	Nuclear receptor
P10644	BXGT007597	cAMP-dependent protein kinase type I-alpha regulatory subunit	5573	reviewed
P11169	BXGT007664	Solute carrier family 2, facilitated glucose transporter member 3	6515	reviewed	Transporter
P11511	BXGT007717	Aromatase	1588	reviewed	Enzyme
P12004	BXGT007766	Proliferating cell nuclear antigen	5111	reviewed	Nucleic acid binding
P14416	BXGT008011	D(2) dopamine receptor	1813	reviewed	G-protein coupled receptor
P14679	BXGT008039	Tyrosinase	7299	reviewed	Enzyme
P14780	BXGT008053	Matrix metalloproteinase-9	4318	reviewed	Enzyme
P15382	BXGT008116	Potassium voltage-gated channel subfamily E member 1	3753	reviewed	Ion channel
P16278	BXGT008213	Beta-galactosidase	2720	reviewed	Enzyme
P17612	BXGT008322	cAMP-dependent protein kinase catalytic subunit alpha	5566	reviewed	Kinase
P19320	BXGT008470	Vascular cell adhesion protein 1	7412	reviewed
P21802	BXGT008691	Fibroblast growth factor receptor 2	2263	reviewed	Kinase
P22413	BXGT008764	Ectonucleotide pyrophosphatase/phosphodiesterase family member 1	5167	reviewed	Enzyme
P22894	BXGT008815	Neutrophil collagenase	4317	reviewed	Enzyme
P29033	BXGT009308	Gap junction beta-2 protein	2706	reviewed	Cell-cell junction
P30041	BXGT009393	Peroxiredoxin-6	9588	reviewed	Enzyme
P30559	BXGT009442	Oxytocin receptor	5021	reviewed	G-protein coupled receptor
P30988	BXGT009491	Calcitonin receptor	799	reviewed	G-protein coupled receptor
P31645	BXGT009558	Sodium-dependent serotonin transporter	6532	reviewed	Transporter
P33527	BXGT009728	Multidrug resistance-associated protein 1	4363	reviewed	Transporter
P34998	BXGT009781	Corticotropin-releasing factor receptor 1	1394	reviewed
P35555	BXGT009845	Fibrillin-1	2200	reviewed	Calcium-binding protein
P36897	BXGT009941	TGF-beta receptor type-1	7046	reviewed	Kinase
P37173	BXGT009970	TGF-beta receptor type-2	7048	reviewed	Kinase
P37288	BXGT009977	Vasopressin V1a receptor	552	reviewed	G-protein coupled receptor
P37840	BXGT010015	Alpha-synuclein	6622	reviewed	Transporter
P41146	BXGT010226	Nociceptin receptor	4987	reviewed	G-protein coupled receptor
P42574	BXGT010317	Caspase-3	836	reviewed	Enzyme
P43220	BXGT010367	Glucagon-like peptide 1 receptor	2740	reviewed	G-protein coupled receptor
P48735	BXGT010657	Isocitrate dehydrogenase [NADP], mitochondrial	3418	reviewed
P49146	BXGT010681	Neuropeptide Y receptor type 2	4887	reviewed	G-protein coupled receptor
P51787	BXGT010889	Potassium voltage-gated channel subfamily KQT member 1	3784	reviewed	Ion channel
P63092	BXGT011495	Guanine nucleotide-binding protein G(s) subunit alpha isoforms short	2778	reviewed
P78508	BXGT011845	ATP-sensitive inward rectifier potassium channel 10	3766	reviewed	Ion channel
P80511	BXGT011914	Protein S100-A12	6283	reviewed	Calcium-binding protein
P84022	BXGT012027	Mothers against decapentaplegic homolog 3	4088	reviewed	Transcription factor
P98164	BXGT012230	Low-density lipoprotein receptor-related protein 2	4036	reviewed
Q01094	BXGT012568	Transcription factor E2F1	1869	reviewed	Nucleic acid binding
Q01484	BXGT012592	Ankyrin-2	287	reviewed
Q05315	BXGT012811	Galectin-10	1178	reviewed	Signaling
Q07157	BXGT012920	Tight junction protein ZO-1	7082	reviewed	Cell-cell junction
Q13402	BXGT013348	Unconventional myosin-VIIa	4647	reviewed	Cellular structure
Q14571	BXGT013485	Inositol 1,4,5-trisphosphate receptor type 2	3709	reviewed	Ion channel
Q14573	BXGT013486	Inositol 1,4,5-trisphosphate receptor type 3	3710	reviewed	Ion channel
Q14643	BXGT013493	Inositol 1,4,5-trisphosphate receptor type 1	3708	reviewed	Ion channel
Q16236	BXGT013624	Nuclear factor erythroid 2-related factor 2	4780	reviewed	Enzyme
Q16665	BXGT013653	Hypoxia-inducible factor 1-alpha	3091	reviewed	Transcription factor
Q8NER1	BXGT018556	Transient receptor potential cation channel subfamily V member 1	7442	reviewed	Ion channel
Q8TDD5	BXGT018809	Mucolipin-3	55283	reviewed	Ion channel
Q99928	BXGT019975	Gamma-aminobutyric acid receptor subunit gamma-3	2567	reviewed	Ion channel
Q9H015	BXGT020432	Solute carrier family 22 member 4	6583	reviewed	Transporter
Q9H9B1	BXGT020501	Histone-lysine N-methyltransferase EHMT1	79813	reviewed	Epigenetic regulator
Q9HCR9	BXGT020537	Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A	50940	reviewed
Q9NSD7	BXGT021205	Relaxin-3 receptor 1	51289	reviewed	G-protein coupled receptor
Q9NXG6	BXGT021246	Transmembrane prolyl 4-hydroxylase	54681	reviewed
Q9UHF0	BXGT021699	Tachykinin-3	6866	reviewed
Q9Y257	BXGT022218	Potassium channel subfamily K member 6	9424	reviewed	Ion channel
O60936	BXGT022857	Nucleolar protein 3	8996	reviewed
O43613	BXGT025666	Orexin receptor type 1	3061	reviewed	G-protein coupled receptor
Q96RD7	BXGT025890	Pannexin-1	24145	reviewed	Ion channel

The disease-related compounds

Compounds

BXGC Id	Compound Name	Structure	Molecular Weight	Number of targets^{?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease}

The disease-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compounds in food^{?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease}