Showing entry for AMYOTROPHIC LATERAL SCLEROSIS 1


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Disease Information
BXGD IdBXGD016144
Disease NameAMYOTROPHIC LATERAL SCLEROSIS 1
Disease CUI IdC1862939
MeSH Codes C18   C10  
Disease Class NameNutritional and Metabolic Diseases; Nervous System Diseases
Semantic TypeDisease or Syndrome
Human Phenotype Ontology Id   
Human Phenotype Ontology Term
Disease Ontology Id DOID:630   DOID:7  
Disease Ontology Class Namegenetic disease; disease of anatomical entity
Disorder Network disorder-protein-compound-food associations
The  disease-related  target proteins
Proteins
Uniport Id BXGT Id Protein Name Gene Status Protein Class
Uniport Id BXGT Id Protein name Gene Status Protein class
O00755 BXGT003945 Protein Wnt-7a 7476 reviewed Signaling
O14618 BXGT004076 Copper chaperone for superoxide dismutase 9973 reviewed Enzyme
O14782 BXGT004098 Kinesin-like protein KIF3C 3797 reviewed Cellular structure
O75746 BXGT005148 Calcium-binding mitochondrial carrier protein Aralar1 8604 reviewed Transporter
P00441 BXGT005540 Superoxide dismutase [Cu-Zn] 6647 reviewed Enzyme
P01011 BXGT005715 Alpha-1-antichymotrypsin 12 reviewed Enzyme modulator
P01034 BXGT005721 Cystatin-C 1471 reviewed
P01100 BXGT005727 Proto-oncogene c-Fos 2353 reviewed Transcription factor
P01130 BXGT005735 Low-density lipoprotein receptor 3949 reviewed
P01375 BXGT005753 Tumor necrosis factor 7124 reviewed Signaling
P02795 BXGT005968 Metallothionein-2 4502 reviewed
P03950 BXGT006116 Angiogenin 283 reviewed
P04040 BXGT006132 Catalase 847 reviewed Enzyme
P04179 BXGT006163 Superoxide dismutase [Mn], mitochondrial 6648 reviewed Enzyme
P04731 BXGT006251 Metallothionein-1A 4489 reviewed
P04732 BXGT006252 Metallothionein-1E 4493 reviewed
P04733 BXGT006253 Metallothionein-1F 4494 reviewed
P04792 BXGT006264 Heat shock protein beta-1 3315 reviewed
P05187 BXGT006339 Alkaline phosphatase, placental type 250 reviewed Enzyme
P07203 BXGT006566 Glutathione peroxidase 1 2876 reviewed Enzyme
P07339 BXGT006604 Cathepsin D 1509 reviewed Enzyme
P07438 BXGT006625 Metallothionein-1B 4490 reviewed
P07737 BXGT006663 Profilin-1 5216 reviewed
P07900 BXGT006696 Heat shock protein HSP 90-alpha 3320 reviewed Chaperone
P08670 BXGT006810 Vimentin 7431 reviewed
P09923 BXGT006942 Intestinal-type alkaline phosphatase 248 reviewed Enzyme
P10415 BXGT007567 Apoptosis regulator Bcl-2 596 reviewed Signaling
P10599 BXGT007583 Thioredoxin 7295 reviewed
P10909 BXGT007630 Clusterin 1191 reviewed
P10997 BXGT007643 Islet amyloid polypeptide 3375 reviewed Signaling
P13640 BXGT007935 Metallothionein-1G 4495 reviewed
P14210 BXGT007994 Hepatocyte growth factor 3082 reviewed Enzyme
P14735 BXGT008042 Insulin-degrading enzyme 3416 reviewed Enzyme
P14867 BXGT008061 Gamma-aminobutyric acid receptor subunit alpha-1 2554 reviewed Ion channel
P15692 BXGT008147 Vascular endothelial growth factor A 7422 reviewed Signaling
P19793 BXGT008515 Retinoic acid receptor RXR-alpha 6256 reviewed Nuclear receptor
P27169 BXGT009161 Serum paraoxonase/arylesterase 1 5444 reviewed
P29466 BXGT009349 Caspase-1 834 reviewed Enzyme
P32119 BXGT009600 Peroxiredoxin-2 7001 reviewed Enzyme
P34932 BXGT009772 Heat shock 70 kDa protein 4 3308 reviewed
P35613 BXGT009856 Basigin 682 reviewed
P35858 BXGT009876 Insulin-like growth factor-binding protein complex acid labile subunit 3483 reviewed Receptor
P42263 BXGT010295 Glutamate receptor 3 2892 reviewed Ion channel
P43004 BXGT010348 Excitatory amino acid transporter 2 6506 reviewed Transporter
P48039 BXGT010607 Melatonin receptor type 1A 4543 reviewed G-protein coupled receptor
P48740 BXGT010659 Mannan-binding lectin serine protease 1 5648 reviewed Enzyme
P49286 BXGT010691 Melatonin receptor type 1B 4544 reviewed G-protein coupled receptor
P49662 BXGT010724 Caspase-4 837 reviewed Enzyme
P52333 BXGT010928 Tyrosine-protein kinase JAK3 3718 reviewed Kinase
P55072 BXGT011103 Transitional endoplasmic reticulum ATPase 7415 reviewed
P62942 BXGT011474 Peptidyl-prolyl cis-trans isomerase FKBP1A 2280 reviewed Enzyme
P68106 BXGT011576 Peptidyl-prolyl cis-trans isomerase FKBP1B 2281 reviewed Enzyme
P80294 BXGT011890 Metallothionein-1H 4496 reviewed
P80297 BXGT011891 Metallothionein-1X 4501 reviewed
P98170 BXGT012231 E3 ubiquitin-protein ligase XIAP 331 reviewed Enzyme modulator
Q00613 BXGT012540 Heat shock factor protein 1 3297 reviewed Transcription factor
Q00688 BXGT012544 Peptidyl-prolyl cis-trans isomerase FKBP3 2287 reviewed
Q02790 BXGT012672 Peptidyl-prolyl cis-trans isomerase FKBP4 2288 reviewed Enzyme
Q03393 BXGT012711 6-pyruvoyl tetrahydrobiopterin synthase 5805 reviewed
Q07817 BXGT012941 Bcl-2-like protein 1 598 reviewed Signaling
Q08722 BXGT013002 Leukocyte surface antigen CD47 961 reviewed
Q12840 BXGT013269 Kinesin heavy chain isoform 5A 3798 reviewed Cellular structure
Q13009 BXGT013305 T-lymphoma invasion and metastasis-inducing protein 1 7074 reviewed
Q13085 BXGT013309 Acetyl-CoA carboxylase 1 31 reviewed
Q13148 BXGT013318 TAR DNA-binding protein 43 23435 reviewed
Q13451 BXGT013356 Peptidyl-prolyl cis-trans isomerase FKBP5 2289 reviewed Enzyme
Q13547 BXGT013373 Histone deacetylase 1 3065 reviewed Epigenetic regulator
Q14203 BXGT013455 Dynactin subunit 1 1639 reviewed Chaperone
Q14982 BXGT013518 Opioid-binding protein/cell adhesion molecule 4978 reviewed
Q15303 BXGT013557 Receptor tyrosine-protein kinase erbB-4 2066 reviewed Kinase
Q16881 BXGT013688 Thioredoxin reductase 1, cytoplasmic 7296 reviewed Enzyme
Q8N339 BXGT018503 Metallothionein-1M 4499 reviewed
Q92793 BXGT019374 CREB-binding protein 1387 reviewed
Q9BVG8 BXGT020144 Kinesin-like protein KIFC3 3801 reviewed Cellular structure
Q9NWM8 BXGT021233 Peptidyl-prolyl cis-trans isomerase FKBP14 55033 reviewed
Q9UHD2 BXGT021697 Serine/threonine-protein kinase TBK1 29110 reviewed Kinase
Q16552 BXGT023419 Interleukin-17A 3605 reviewed
P17535 BXGT023437 Transcription factor jun-D 3727 reviewed Transcription factor
Q6SZW1 BXGT025034 NAD(+) hydrolase SARM1 23098 reviewed
The  disease-related  compounds
Compounds
BXGC Id Compound Name Structure Molecular Weight Number of targets?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease
The  disease-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compounds in food?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease