Showing entry for Casein kinase II subunit beta


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT011566
Protein NameCasein kinase II subunit beta
Uniport IdP67870
GeneCSNK2B
Gene Id1460
DomainCK_II_beta
Pfam PF01214  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
2. Genetic Information Processing 2.2 Translation hsa03008 Ribosome biogenesis in eukaryotes
3. Environmental Information Processing 3.2 Signal transduction hsa04064 NF-kappa B signaling pathway
4. Cellular Processes 4.1 Transport and catabolism hsa04137 Mitophagy - animal
3. Environmental Information Processing 3.2 Signal transduction hsa04310 Wnt signaling pathway
4. Cellular Processes 4.3 Cellular community - eukaryotes hsa04520 Adherens junction
6. Human Diseases 6.9 Infectious diseases: Viral hsa05162 Measles
6. Human Diseases 6.1 Cancers: Overview hsa05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0033211 adiponectin-activated signaling pathway
Biological Process GO:0034622 cellular protein-containing complex assembly
Biological Process GO:0061154 endothelial tube morphogenesis
Biological Process GO:0097421 liver regeneration
Biological Process GO:0016236 macroautophagy
Biological Process GO:0043537 negative regulation of blood vessel endothelial cell migration
Biological Process GO:0008285 negative regulation of cell population proliferation
Biological Process GO:0043312 neutrophil degranulation
Biological Process GO:0018107 peptidyl-threonine phosphorylation
Biological Process GO:0006656 phosphatidylcholine biosynthetic process
Biological Process GO:0032927 positive regulation of activin receptor signaling pathway
Biological Process GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation
Biological Process GO:0006457 protein folding
Biological Process GO:0051101 regulation of DNA binding
Biological Process GO:1901796 regulation of signal transduction by p53 class mediator
Biological Process GO:0033574 response to testosterone
Biological Process GO:0007165 signal transduction
Biological Process GO:0016055 Wnt signaling pathway
molecular function GO:0003682 chromatin binding
molecular function GO:0042802 identical protein binding
molecular function GO:0046872 metal ion binding
molecular function GO:0019904 protein domain specific binding
molecular function GO:0019887 protein kinase regulator activity
molecular function GO:0004674 protein serine/threonine kinase activity
molecular function GO:0043021 ribonucleoprotein complex binding
molecular function GO:0005102 signaling receptor binding
molecular function GO:0008134 transcription factor binding
cellular component GO:0000785 chromatin
cellular component GO:0005929 cilium
cellular component GO:0005737 cytoplasm
cellular component GO:0005829 cytosol
cellular component GO:0070062 extracellular exosome
cellular component GO:0005576 extracellular region
cellular component GO:1904813 ficolin-1-rich granule lumen
cellular component GO:0016363 nuclear matrix
cellular component GO:0005654 nucleoplasm
cellular component GO:0005634 nucleus
cellular component GO:0005886 plasma membrane
cellular component GO:0005956 protein kinase CK2 complex
cellular component GO:0034774 secretory granule lumen
Reactome
Pathway Id Pathway Name
R-HSA-1257604 PIP3 activates AKT signaling
R-HSA-1266738 Developmental Biology
R-HSA-1430728 Metabolism
R-HSA-1483191 Synthesis of PC
R-HSA-1483206 Glycerophospholipid biosynthesis
R-HSA-1483257 Phospholipid metabolism
R-HSA-162582 Signal Transduction
R-HSA-1632852 Macroautophagy
R-HSA-1640170 Cell Cycle
R-HSA-168249 Innate Immune System
R-HSA-168256 Immune System
R-HSA-195721 Signaling by WNT
R-HSA-201681 TCF dependent signaling in response to WNT
R-HSA-201688 WNT mediated activation of DVL
R-HSA-212436 Generic Transcription Pathway
R-HSA-2514853 Condensation of Prometaphase Chromosomes
R-HSA-3700989 Transcriptional Regulation by TP53
R-HSA-373760 L1CAM interactions
R-HSA-390466 Chaperonin-mediated protein folding
R-HSA-391251 Protein folding
R-HSA-392499 Metabolism of proteins
R-HSA-422475 Axon guidance
R-HSA-445144 Signal transduction by L1
R-HSA-5205647 Mitophagy
R-HSA-556833 Metabolism of lipids
R-HSA-5633007 Regulation of TP53 Activity
R-HSA-6798695 Neutrophil degranulation
R-HSA-6804756 Regulation of TP53 Activity through Phosphorylation
R-HSA-6807070 PTEN Regulation
R-HSA-6814122 Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding
R-HSA-68877 Mitotic Prometaphase
R-HSA-68886 M Phase
R-HSA-69278 Cell Cycle, Mitotic
R-HSA-73857 RNA Polymerase II Transcription
R-HSA-74160 Gene expression (Transcription)
R-HSA-8878171 Transcriptional regulation by RUNX1
R-HSA-8934903 Receptor Mediated Mitophagy
R-HSA-8939243 RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known
R-HSA-8948751 Regulation of PTEN stability and activity
R-HSA-9006925 Intracellular signaling by second messengers
R-HSA-9612973 Autophagy
R-HSA-9663891 Selective autophagy
R-HSA-9675108 Nervous system development
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0003873 BXGD000236 Rheumatoid Arthritis Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Immune System Diseases
C0006142 BXGD000374 Malignant neoplasm of breast Neoplasms; Skin and Connective Tissue Diseases
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0007114 BXGD000431 Malignant neoplasm of skin Neoplasms; Skin and Connective Tissue Diseases
C0007137 BXGD000445 Squamous cell carcinoma Neoplasms
C0011854 BXGD000753 Diabetes Mellitus, Insulin-Dependent Nutritional and Metabolic Diseases; Immune System Diseases; Endocrine System Diseases
C0014170 BXGD000902 Endometrial Neoplasms Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0014544 BXGD000926 Epilepsy Nervous System Diseases
C0014550 BXGD000930 Myoclonic Epilepsy Nervous System Diseases
C0015967 BXGD001030 Fever Pathological Conditions, Signs and Symptoms
C0023493 BXGD001672 Adult T-Cell Lymphoma/Leukemia Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0024137 BXGD001737 Lupus Erythematosus, Cutaneous Skin and Connective Tissue Diseases
C0024141 BXGD001740 Lupus Erythematosus, Systemic Skin and Connective Tissue Diseases; Immune System Diseases
C0027051 BXGD001963 Myocardial Infarction Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0032580 BXGD002362 Adenomatous Polyposis Coli Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Digestive System Diseases; Neoplasms
C0036341 BXGD002600 Schizophrenia Mental Disorders
C0036572 BXGD002625 Seizures Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0037286 BXGD002681 Skin Neoplasms Neoplasms; Skin and Connective Tissue Diseases
C0079744 BXGD003090 Diffuse Large B-Cell Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0149678 BXGD003346 Epstein-Barr Virus Infections Infections
C0178874 BXGD004037 Tumor Progression Pathological Conditions, Signs and Symptoms
C0206698 BXGD004248 Cholangiocarcinoma Neoplasms
C0220668 BXGD004317 Congenital contractural arachnodactyly Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0242379 BXGD005157 Malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C0424605 BXGD008535 Developmental delay (disorder) Mental Disorders
C0557874 BXGD009444 Global developmental delay
C0678222 BXGD009749 Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C0684249 BXGD009790 Carcinoma of lung Neoplasms; Respiratory Tract Diseases
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C1306460 BXGD012362 Primary malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C1535926 BXGD013322 Neurodevelopmental Disorders Mental Disorders
C1856184 BXGD015583 HEMIHYPERPLASIA, ISOLATED Pathological Conditions, Signs and Symptoms
C2239176 BXGD016965 Liver carcinoma Digestive System Diseases; Neoplasms
C3714756 BXGD019429 Intellectual Disability Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000332 Fisetin 286.24
BXGC0000340 Kaempferol 286.24
BXGC0000655 Harmalol 200.24
BXGC0001544 Harmaline 214.26
BXGC0001545 Harmine 212.25
BXGC0002018 Morin 302.24
BXGC0002071 Apigenin 270.24
BXGC0002588 Magnesium 24.31
BXGC0004115 Norharman 168.19
BXGC0005683 Quercetin 302.24
BXGC0006193 Ellagic acid 302.19
BXGC0006306 Myricetin 318.24
BXGC0006635 Luteolin 286.24
BXGC0007014 Harman 182.22
BXGC0007029 Emodin 270.24
BXGC0012352 Chelerythrine 348.12
BXGC0018843 Quinalizarin 272.03
BXGC0024476 Lantic acid 470.34
BXGC0024554 D-luciferin 280
BXGC0034256 Rottlerin 516.18
BXGC0038577 Magnolol 266.13
BXGC0044857 Sp-600125 220.06
BXGC0045254 Sb-202190 331.11
BXGC0045681 SR-01000500270 362.17
BXGC0051873 Sl-0101 516.13
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein