adisease

Showing entry for Speech Disorders

General Disease Information
BXGD Id	BXGD002706
Disease Name	Speech Disorders
Disease CUI Id	C0037822
MeSH Codes	C23 C10
Disease Class Name	Pathological Conditions, Signs and Symptoms; Nervous System Diseases
Semantic Type	Disease or Syndrome
Human Phenotype Ontology Id	HP:0000707
Human Phenotype Ontology Term	Abnormality of the nervous system
Disease Ontology Id	DOID:150
Disease Ontology Class Name	disease of mental health
Disorder Network	disorder-protein-compound-food associations

The disease-related target proteins

Proteins

Uniport Id	BXGT Id	Protein Name	Gene	Status	Protein Class
Uniport Id	BXGT Id	Protein name	Gene	Status	Protein class
O00462	BXGT003925	Beta-mannosidase	4126	reviewed	Enzyme
O00571	BXGT003938	ATP-dependent RNA helicase DDX3X	1654	reviewed
O15409	BXGT004166	Forkhead box protein P2	93986	reviewed
O43424	BXGT004592	Glutamate receptor ionotropic, delta-2	2895	reviewed	Ion channel
O43451	BXGT004594	Maltase-glucoamylase, intestinal	8972	reviewed	Enzyme
O43914	BXGT004635	TYRO protein tyrosine kinase-binding protein	7305	reviewed
O75030	BXGT005096	Microphthalmia-associated transcription factor	4286	reviewed
O75914	BXGT005165	Serine/threonine-protein kinase PAK 3	5063	reviewed	Kinase
O94903	BXGT005339	Pyridoxal phosphate homeostasis protein	11212	reviewed
P01137	BXGT005737	Transforming growth factor beta-1 proprotein	7040	reviewed	Signaling
P01889	BXGT005809	HLA class I histocompatibility antigen, B-7 alpha chain	3106	reviewed
P04062	BXGT006140	Lysosomal acid glucosylceramidase	2629	reviewed
P05089	BXGT006310	Arginase-1	383	reviewed	Enzyme
P08842	BXGT006830	Steryl-sulfatase	412	reviewed	Enzyme
P10636	BXGT007596	Microtubule-associated protein tau	4137	reviewed
P13612	BXGT007928	Integrin alpha-4	3676	reviewed
P14410	BXGT008009	Sucrase-isomaltase, intestinal	6476	reviewed	Enzyme
P17735	BXGT008335	Tyrosine aminotransferase	6898	reviewed
P19367	BXGT008476	Hexokinase-1	3098	reviewed	Kinase
P20933	BXGT008618	N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase	175	reviewed	Enzyme
P24557	BXGT008976	Thromboxane-A synthase	6916	reviewed
P27797	BXGT009206	Calreticulin	811	reviewed	Calcium-binding protein
P27986	BXGT009216	Phosphatidylinositol 3-kinase regulatory subunit alpha	5295	reviewed	Kinase
P29460	BXGT009348	Interleukin-12 subunit beta	3593	reviewed	Signaling
P30988	BXGT009491	Calcitonin receptor	799	reviewed	G-protein coupled receptor
P35222	BXGT009799	Catenin beta-1	1499	reviewed
P40337	BXGT010174	von Hippel-Lindau disease tumor suppressor	7428	reviewed	Enzyme
P41227	BXGT010238	N-alpha-acetyltransferase 10	8260	reviewed	Enzyme
P42345	BXGT010304	Serine/threonine-protein kinase mTOR	2475	reviewed	Kinase
P42357	BXGT010306	Histidine ammonia-lyase	3034	reviewed
P43026	BXGT010351	Growth/differentiation factor 5	8200	reviewed	Signaling
P48029	BXGT010606	Sodium- and chloride-dependent creatine transporter 1	6535	reviewed	Transporter
P49419	BXGT010705	Alpha-aminoadipic semialdehyde dehydrogenase	501	reviewed	Enzyme
P49638	BXGT010720	Alpha-tocopherol transfer protein	7274	reviewed	Transporter
P50416	BXGT010797	Carnitine O-palmitoyltransferase 1, liver isoform	1374	reviewed	Enzyme
P51812	BXGT010893	Ribosomal protein S6 kinase alpha-3	6197	reviewed	Kinase
P56945	BXGT011206	Breast cancer anti-estrogen resistance protein 1	9564	reviewed
P58335	BXGT011233	Anthrax toxin receptor 2	118429	reviewed	Receptor
P60484	BXGT011307	Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN	5728	reviewed	Enzyme
P61073	BXGT011352	C-X-C chemokine receptor type 4	7852	reviewed	G-protein coupled receptor
P62258	BXGT011415	14-3-3 protein epsilon	7531	reviewed	Chaperone
P69905	BXGT011649	Hemoglobin subunit alpha	3040	reviewed
P78508	BXGT011845	ATP-sensitive inward rectifier potassium channel 10	3766	reviewed	Ion channel
Q03164	BXGT012700	Histone-lysine N-methyltransferase 2A	4297	reviewed
Q06787	BXGT012890	Synaptic functional regulator FMR1	2332	reviewed	Nucleic acid binding
Q12879	BXGT013275	Glutamate receptor ionotropic, NMDA 2A	2903	reviewed	Ion channel
Q13510	BXGT013367	Acid ceramidase	427	reviewed	Enzyme
Q13586	BXGT013380	Stromal interaction molecule 1	6786	reviewed
Q14683	BXGT013500	Structural maintenance of chromosomes protein 1A	8243	reviewed
Q15067	BXGT013532	Peroxisomal acyl-coenzyme A oxidase 1	51	reviewed	Enzyme
Q15223	BXGT013551	Nectin-1	5818	reviewed
Q6N021	BXGT016378	Methylcytosine dioxygenase TET2	54790	reviewed
Q8NFD5	BXGT018560	AT-rich interactive domain-containing protein 1B	57492	reviewed
Q8WZA1	BXGT019024	Protein O-linked-mannose beta-1,2-N-acetylglucosaminyltransferase 1	55624	reviewed
Q96D31	BXGT019635	Calcium release-activated calcium channel protein 1	84876	reviewed	Ion channel
Q99519	BXGT019928	Sialidase-1	4758	reviewed	Enzyme
Q9BY41	BXGT020180	Histone deacetylase 8	55869	reviewed	Epigenetic regulator
Q9H0F7	BXGT020435	ADP-ribosylation factor-like protein 6	84100	reviewed
Q9H4W6	BXGT020478	Transcription factor COE3	253738	reviewed
Q9UHD8	BXGT021698	Septin-9	10801	reviewed	Enzyme modulator
Q9UMX1	BXGT021778	Suppressor of fused homolog	51684	reviewed
P35240	BXGT022927	Merlin	4771	reviewed
P07954	BXGT023939	Fumarate hydratase, mitochondrial	2271	reviewed	Enzyme
Q9H9S5	BXGT024623	Fukutin-related protein	79147	reviewed
P51608	BXGT025073	Methyl-CpG-binding protein 2	4204	reviewed	Epigenetic regulator
Q96DA2	BXGT025522	Ras-related protein Rab-39B	116442	reviewed
Q05086	BXGT025648	Ubiquitin-protein ligase E3A	7337	reviewed
Q9UQE7	BXGT025899	Structural maintenance of chromosomes protein 3	9126	reviewed

The disease-related compounds

Compounds

BXGC Id	Compound Name	Structure	Molecular Weight	Number of targets^{?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease}

The disease-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compounds in food^{?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease}