adisease

Showing entry for Autistic behavior

General Disease Information
BXGD Id	BXGD011127
Disease Name	Autistic behavior
Disease CUI Id	C0856975
MeSH Codes	F01
Disease Class Name	Behavior and Behavior Mechanisms
Semantic Type	Mental or Behavioral Dysfunction
Human Phenotype Ontology Id	HP:0000707
Human Phenotype Ontology Term	Abnormality of the nervous system
Disease Ontology Id
Disease Ontology Class Name
Disorder Network	disorder-protein-compound-food associations

The disease-related target proteins

Proteins

Uniport Id	BXGT Id	Protein Name	Gene	Status	Protein Class
Uniport Id	BXGT Id	Protein name	Gene	Status	Protein class
O00571	BXGT003938	ATP-dependent RNA helicase DDX3X	1654	reviewed
O14646	BXGT004079	Chromodomain-helicase-DNA-binding protein 1	1105	reviewed
O14764	BXGT004094	Gamma-aminobutyric acid receptor subunit delta	2563	reviewed	Ion channel
O14770	BXGT004095	Homeobox protein Meis2	4212	reviewed	Enzyme
O14936	BXGT004114	Peripheral plasma membrane protein CASK	8573	reviewed	Kinase
O15054	BXGT004121	Lysine-specific demethylase 6B	23135	reviewed	Epigenetic regulator
O15297	BXGT004149	Protein phosphatase 1D	8493	reviewed	Enzyme
O15409	BXGT004166	Forkhead box protein P2	93986	reviewed
O15553	BXGT004181	Pyrin	4210	reviewed
O60488	BXGT004878	Long-chain-fatty-acid--CoA ligase 4	2182	reviewed	Enzyme
O60741	BXGT004897	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1	348980	reviewed
O75914	BXGT005165	Serine/threonine-protein kinase PAK 3	5063	reviewed	Kinase
O76039	BXGT005171	Cyclin-dependent kinase-like 5	6792	reviewed	Kinase
P01133	BXGT005736	Pro-epidermal growth factor	1950	reviewed
P02786	BXGT005961	Transferrin receptor protein 1	7037	reviewed	Enzyme
P09884	BXGT006937	DNA polymerase alpha catalytic subunit	5422	reviewed
P11233	BXGT007678	Ras-related protein Ral-A	5898	reviewed	Enzyme modulator
P13637	BXGT007933	Sodium/potassium-transporting ATPase subunit alpha-3	478	reviewed	Transporter
P15311	BXGT008106	Ezrin	7430	reviewed	Cellular structure
P15884	BXGT008166	Transcription factor 4	6925	reviewed	Transcription factor
P17787	BXGT008341	Neuronal acetylcholine receptor subunit beta-2	1141	reviewed	Ion channel
P18507	BXGT008411	Gamma-aminobutyric acid receptor subunit gamma-2	2566	reviewed	Ion channel
P21397	BXGT008644	Amine oxidase [flavin-containing] A	4128	reviewed
P21675	BXGT008678	Transcription initiation factor TFIID subunit 1	6872	reviewed	Kinase
P28335	BXGT009255	5-hydroxytryptamine receptor 2C	3358	reviewed	G-protein coupled receptor
P28472	BXGT009260	Gamma-aminobutyric acid receptor subunit beta-3	2562	reviewed	Ion channel
P30153	BXGT009409	Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform	5518	reviewed	Enzyme
P30531	BXGT009432	Sodium- and chloride-dependent GABA transporter 1	6529	reviewed	Transporter
P31645	BXGT009558	Sodium-dependent serotonin transporter	6532	reviewed	Transporter
P35222	BXGT009799	Catenin beta-1	1499	reviewed
P35398	BXGT009825	Nuclear receptor ROR-alpha	6095	reviewed	Nuclear receptor
P35498	BXGT009838	Sodium channel protein type 1 subunit alpha	6323	reviewed	Ion channel
P41227	BXGT010238	N-alpha-acetyltransferase 10	8260	reviewed	Enzyme
P42345	BXGT010304	Serine/threonine-protein kinase mTOR	2475	reviewed	Kinase
P42858	BXGT010341	Huntingtin	3064	reviewed
P48029	BXGT010606	Sodium- and chloride-dependent creatine transporter 1	6535	reviewed	Transporter
P49589	BXGT010714	Cysteine--tRNA ligase, cytoplasmic	833	reviewed	Enzyme
P49591	BXGT010715	Serine--tRNA ligase, cytoplasmic	6301	reviewed	Enzyme
P49711	BXGT010728	Transcriptional repressor CTCF	10664	reviewed	Transcription factor
P50052	BXGT010768	Type-2 angiotensin II receptor	186	reviewed	G-protein coupled receptor
P50135	BXGT010776	Histamine N-methyltransferase	3176	reviewed
P51688	BXGT010883	N-sulphoglucosamine sulphohydrolase	6448	reviewed	Enzyme
P51812	BXGT010893	Ribosomal protein S6 kinase alpha-3	6197	reviewed	Kinase
P53779	BXGT011014	Mitogen-activated protein kinase 10	5602	reviewed	Kinase
P57059	BXGT011210	Serine/threonine-protein kinase SIK1	150094	reviewed
P58400	BXGT011235	Neurexin-1-beta	9378	reviewed
P60484	BXGT011307	Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN	5728	reviewed	Enzyme
P62258	BXGT011415	14-3-3 protein epsilon	7531	reviewed	Chaperone
P62266	BXGT011416	40S ribosomal protein S23	6228	reviewed	Nucleic acid binding
P63027	BXGT011487	Vesicle-associated membrane protein 2	6844	reviewed
P67775	BXGT011563	Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform	5515	reviewed
Q00604	BXGT012538	Norrin	4693	reviewed
Q05193	BXGT012810	Dynamin-1	1759	reviewed	Enzyme modulator
Q05586	BXGT012826	Glutamate receptor ionotropic, NMDA 1	2902	reviewed	Ion channel
Q06787	BXGT012890	Synaptic functional regulator FMR1	2332	reviewed	Nucleic acid binding
Q09470	BXGT013037	Potassium voltage-gated channel subfamily A member 1	3736	reviewed	Ion channel
Q11203	BXGT013218	CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase	6487	reviewed
Q12830	BXGT013268	Nucleosome-remodeling factor subunit BPTF	2186	reviewed
Q12882	BXGT013276	Dihydropyrimidine dehydrogenase [NADP(+)]	1806	reviewed	Enzyme
Q13002	BXGT013303	Glutamate receptor ionotropic, kainate 2	2898	reviewed	Ion channel
Q13148	BXGT013318	TAR DNA-binding protein 43	23435	reviewed
Q13224	BXGT013328	Glutamate receptor ionotropic, NMDA 2B	2904	reviewed	Ion channel
Q13255	BXGT013332	Metabotropic glutamate receptor 1	2911	reviewed	G-protein coupled receptor
Q14004	BXGT013435	Cyclin-dependent kinase 13	8621	reviewed	Kinase
Q15858	BXGT013610	Sodium channel protein type 9 subunit alpha	6335	reviewed	Ion channel
Q16099	BXGT013620	Glutamate receptor ionotropic, kainate 4	2900	reviewed	Ion channel
Q86UE8	BXGT017612	Serine/threonine-protein kinase tousled-like 2	11011	reviewed	Kinase
Q8IWQ3	BXGT018355	Serine/threonine-protein kinase BRSK2	9024	reviewed	Kinase
Q8N0W4	BXGT018492	Neuroligin-4, X-linked	57502	reviewed
Q8NFD5	BXGT018560	AT-rich interactive domain-containing protein 1B	57492	reviewed
Q92796	BXGT019376	Disks large homolog 3	1741	reviewed
Q96SW2	BXGT019743	Protein cereblon	51185	reviewed	Enzyme
Q96T60	BXGT019745	Bifunctional polynucleotide phosphatase/kinase	11284	reviewed
Q99250	BXGT019913	Sodium channel protein type 2 subunit alpha	6326	reviewed	Ion channel
Q9BXJ9	BXGT020170	N-alpha-acetyltransferase 15, NatA auxiliary subunit	80155	reviewed	Enzyme
Q9BYW2	BXGT020192	Histone-lysine N-methyltransferase SETD2	29072	reviewed	Epigenetic regulator
Q9H4W6	BXGT020478	Transcription factor COE3	253738	reviewed
Q9H8M5	BXGT020496	Metal transporter CNNM2	54805	reviewed
Q9HA77	BXGT020504	Probable cysteine--tRNA ligase, mitochondrial	79587	reviewed	Enzyme
Q9NRF2	BXGT021185	SH2B adapter protein 1	25970	reviewed
Q9NZN1	BXGT021279	Interleukin-1 receptor accessory protein-like 1	11141	reviewed	Receptor
Q9UGL1	BXGT021685	Lysine-specific demethylase 5B	10765	reviewed	Epigenetic regulator
Q9UGM6	BXGT021687	Tryptophan--tRNA ligase, mitochondrial	10352	reviewed
Q9UKE5	BXGT021741	TRAF2 and NCK-interacting protein kinase	23043	reviewed	Kinase
Q9UKM7	BXGT021747	Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase	11253	reviewed	Chaperone
Q9ULJ6	BXGT021761	Zinc finger MIZ domain-containing protein 1	57178	reviewed
Q9Y2H9	BXGT022234	Microtubule-associated serine/threonine-protein kinase 1	22983	reviewed	Kinase
Q9Y6K1	BXGT022331	DNA (cytosine-5)-methyltransferase 3A	1788	reviewed
Q9Y5W7	BXGT022783	Sorting nexin-14	57231	reviewed	Enzyme modulator
Q96C86	BXGT022803	m7GpppX diphosphatase	28960	reviewed	Enzyme
Q8NEZ4	BXGT024850	Histone-lysine N-methyltransferase 2C	58508	reviewed
P51608	BXGT025073	Methyl-CpG-binding protein 2	4204	reviewed	Epigenetic regulator
Q96DA2	BXGT025522	Ras-related protein Rab-39B	116442	reviewed
Q8TAB3	BXGT025819	Protocadherin-19	57526	reviewed
Q8WXI2	BXGT026145	Connector enhancer of kinase suppressor of ras 2	22866	reviewed
P09471	BXGT026153	Guanine nucleotide-binding protein G(o) subunit alpha	2775	reviewed	Enzyme modulator

The disease-related compounds

Compounds

BXGC Id	Compound Name	Structure	Molecular Weight	Number of targets^{?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease}

The disease-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compounds in food^{?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease}