adisease

Showing entry for Arthritis, Gouty

General Disease Information
BXGD Id	BXGD000233
Disease Name	Arthritis, Gouty
Disease CUI Id	C0003868
MeSH Codes	C16 C18 C05
Disease Class Name	Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Musculoskeletal Diseases
Semantic Type	Disease or Syndrome
Human Phenotype Ontology Id	HP:0000924
Human Phenotype Ontology Term	Abnormality of the skeletal system
Disease Ontology Id	DOID:7
Disease Ontology Class Name	disease of anatomical entity
Disorder Network	disorder-protein-compound-food associations

The disease-related target proteins

Proteins

Uniport Id	BXGT Id	Protein Name	Gene	Status	Protein Class
Uniport Id	BXGT Id	Protein name	Gene	Status	Protein class
O00194	BXGT003892	Ras-related protein Rab-27B	5874	reviewed
O00206	BXGT003894	Toll-like receptor 4	7099	reviewed
O15245	BXGT004141	Solute carrier family 22 member 1	6580	reviewed	Transporter
O15553	BXGT004181	Pyrin	4210	reviewed
O43929	BXGT004638	Origin recognition complex subunit 4	5000	reviewed	Nucleic acid binding
O60507	BXGT004880	Protein-tyrosine sulfotransferase 1	8460	reviewed	Enzyme
O60706	BXGT004896	ATP-binding cassette sub-family C member 9	10060	reviewed	Transporter
O60885	BXGT004906	Bromodomain-containing protein 4	23476	reviewed	Epigenetic regulator
O75173	BXGT005105	A disintegrin and metalloproteinase with thrombospondin motifs 4	9507	reviewed	Enzyme
O75311	BXGT005109	Glycine receptor subunit alpha-3	8001	reviewed	Ion channel
O94788	BXGT005333	Retinal dehydrogenase 2	8854	reviewed	Enzyme
O95477	BXGT005383	Phospholipid-transporting ATPase ABCA1	19	reviewed	Transporter
P00492	BXGT005556	Hypoxanthine-guanine phosphoribosyltransferase	3251	reviewed	Enzyme
P01031	BXGT005720	Complement C5	727	reviewed	Enzyme modulator
P01189	BXGT005742	Pro-opiomelanocortin	5443	reviewed
P01215	BXGT005743	Glycoprotein hormones alpha chain	1081	reviewed
P01583	BXGT005771	Interleukin-1 alpha	3552	reviewed
P01584	BXGT005772	Interleukin-1 beta	3553	reviewed
P02647	BXGT005908	Apolipoprotein A-I	335	reviewed
P02741	BXGT005936	C-reactive protein	1401	reviewed
P04908	BXGT006283	Histone H2A type 1-B/E	8335	reviewed	Nucleic acid binding
P05091	BXGT006312	Aldehyde dehydrogenase, mitochondrial	217	reviewed	Enzyme
P05181	BXGT006337	Cytochrome P450 2E1	1571	reviewed
P05231	BXGT006345	Interleukin-6	3569	reviewed
P06213	BXGT006425	Insulin receptor	3643	reviewed	Kinase
P08069	BXGT006723	Insulin-like growth factor 1 receptor	3480	reviewed	Kinase
P09917	BXGT006941	Arachidonate 5-lipoxygenase	240	reviewed	Enzyme
P10145	BXGT007542	Interleukin-8	3576	reviewed	Signaling
P10632	BXGT007592	Cytochrome P450 2C8	1558	reviewed
P10809	BXGT007617	60 kDa heat shock protein, mitochondrial	3329	reviewed
P10826	BXGT007622	Retinoic acid receptor beta	5915	reviewed	Nuclear receptor
P11217	BXGT007674	Glycogen phosphorylase, muscle form	5837	reviewed	Enzyme
P11473	BXGT007709	Vitamin D3 receptor	7421	reviewed	Nuclear receptor
P13569	BXGT007923	Cystic fibrosis transmembrane conductance regulator	1080	reviewed	Ion channel
P14210	BXGT007994	Hepatocyte growth factor	3082	reviewed	Enzyme
P14780	BXGT008053	Matrix metalloproteinase-9	4318	reviewed	Enzyme
P15941	BXGT008176	Mucin-1	4582	reviewed
P17252	BXGT008294	Protein kinase C alpha type	5578	reviewed	Kinase
P21730	BXGT008687	C5a anaphylatoxin chemotactic receptor 1	728	reviewed	G-protein coupled receptor
P21802	BXGT008691	Fibroblast growth factor receptor 2	2263	reviewed	Kinase
P23468	BXGT008870	Receptor-type tyrosine-protein phosphatase delta	5789	reviewed	Enzyme
P27037	BXGT009153	Activin receptor type-2A	92	reviewed	Kinase
P29466	BXGT009349	Caspase-1	834	reviewed	Enzyme
P30411	BXGT009424	B2 bradykinin receptor	624	reviewed	G-protein coupled receptor
P31639	BXGT009556	Sodium/glucose cotransporter 2	6524	reviewed	Transporter
P37231	BXGT009972	Peroxisome proliferator-activated receptor gamma	5468	reviewed	Nuclear receptor
P41231	BXGT010240	P2Y purinoceptor 2	5029	reviewed	G-protein coupled receptor
P42685	BXGT010332	Tyrosine-protein kinase FRK	2444	reviewed	Kinase
P47900	BXGT010595	P2Y purinoceptor 1	5028	reviewed	G-protein coupled receptor
P51575	BXGT010861	P2X purinoceptor 1	5023	reviewed	Ion channel
P51787	BXGT010889	Potassium voltage-gated channel subfamily KQT member 1	3784	reviewed	Ion channel
P56373	BXGT011164	P2X purinoceptor 3	5024	reviewed	Ion channel
P62807	BXGT011458	Histone H2B type 1-C/E/F/G/I	8347	reviewed
Q03181	BXGT012701	Peroxisome proliferator-activated receptor delta	5467	reviewed	Nuclear receptor
Q09428	BXGT013036	ATP-binding cassette sub-family C member 8	6833	reviewed	Transporter
Q12851	BXGT013271	Mitogen-activated protein kinase kinase kinase kinase 2	5871	reviewed	Kinase
Q13563	BXGT013377	Polycystin-2	5311	reviewed	Ion channel
Q13733	BXGT013394	Sodium/potassium-transporting ATPase subunit alpha-4	480	reviewed	Transporter
Q14116	BXGT013442	Interleukin-18	3606	reviewed
Q14123	BXGT013445	Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C	5137	reviewed
Q14397	BXGT013467	Glucokinase regulatory protein	2646	reviewed
Q14541	BXGT013481	Hepatocyte nuclear factor 4-gamma	3174	reviewed	Nuclear receptor
Q15036	BXGT013526	Sorting nexin-17	9784	reviewed
Q16236	BXGT013624	Nuclear factor erythroid 2-related factor 2	4780	reviewed	Enzyme
Q16584	BXGT013642	Mitogen-activated protein kinase kinase kinase 11	4296	reviewed	Kinase
Q16659	BXGT013652	Mitogen-activated protein kinase 6	5597	reviewed	Kinase
Q30201	BXGT014297	Hereditary hemochromatosis protein	3077	reviewed
Q92993	BXGT019403	Histone acetyltransferase KAT5	10524	reviewed
Q96EB6	BXGT019646	NAD-dependent protein deacetylase sirtuin-1	23411	reviewed	Epigenetic regulator
Q96P20	BXGT019704	NACHT, LRR and PYD domains-containing protein 3	114548	reviewed
Q96QV6	BXGT019723	Histone H2A type 1-A	221613	reviewed	Nucleic acid binding
Q96S37	BXGT019737	Solute carrier family 22 member 12	116085	reviewed	Transporter
Q99572	BXGT019935	P2X purinoceptor 7	5027	reviewed	Ion channel
Q99700	BXGT019949	Ataxin-2	6311	reviewed	Nucleic acid binding
Q9BWU0	BXGT020155	Kanadaptin	22950	reviewed
Q9HC29	BXGT020526	Nucleotide-binding oligomerization domain-containing protein 2	64127	reviewed	Enzyme
Q9NSA0	BXGT021202	Solute carrier family 22 member 11	55867	reviewed	Transporter
Q9NWB1	BXGT021231	RNA binding protein fox-1 homolog 1	54715	reviewed	Nucleic acid binding
Q9UBL9	BXGT021656	P2X purinoceptor 2	22953	reviewed	Ion channel
Q9UGJ0	BXGT021683	5'-AMP-activated protein kinase subunit gamma-2	51422	reviewed	Enzyme modulator
Q9UNQ0	BXGT021792	ATP-binding cassette sub-family G member 2	9429	reviewed	Transporter
Q9UQB8	BXGT021809	Brain-specific angiogenesis inhibitor 1-associated protein 2	10458	reviewed	Receptor
Q9Y289	BXGT022226	Sodium-dependent multivitamin transporter	8884	reviewed	Transporter
Q9Y694	BXGT022321	Solute carrier family 22 member 7	10864	reviewed	Transporter
Q5T2W1	BXGT023979	Na(+)/H(+) exchange regulatory cofactor NHE-RF3	5174	reviewed
Q9BQ69	BXGT026098	ADP-ribose glycohydrolase MACROD1	28992	reviewed

The disease-related compounds

Compounds

BXGC Id	Compound Name	Structure	Molecular Weight	Number of targets^{?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease}

The disease-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compounds in food^{?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease}