adisease

Showing entry for Gout

General Disease Information
BXGD Id	BXGD001172
Disease Name	Gout
Disease CUI Id	C0018099
MeSH Codes	C16 C18 C05
Disease Class Name	Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Musculoskeletal Diseases
Semantic Type	Disease or Syndrome
Human Phenotype Ontology Id	HP:0000924
Human Phenotype Ontology Term	Abnormality of the skeletal system
Disease Ontology Id	DOID:7
Disease Ontology Class Name	disease of anatomical entity
Disorder Network	disorder-protein-compound-food associations

The disease-related target proteins

Proteins

Uniport Id	BXGT Id	Protein Name	Gene	Status	Protein Class
Uniport Id	BXGT Id	Protein name	Gene	Status	Protein class
O00194	BXGT003892	Ras-related protein Rab-27B	5874	reviewed
O15245	BXGT004141	Solute carrier family 22 member 1	6580	reviewed	Transporter
O43318	BXGT004586	Mitogen-activated protein kinase kinase kinase 7	6885	reviewed	Kinase
O43826	BXGT004629	Glucose-6-phosphate exchanger SLC37A4	2542	reviewed	Transporter
O43929	BXGT004638	Origin recognition complex subunit 4	5000	reviewed	Nucleic acid binding
O60507	BXGT004880	Protein-tyrosine sulfotransferase 1	8460	reviewed	Enzyme
O60706	BXGT004896	ATP-binding cassette sub-family C member 9	10060	reviewed	Transporter
O75581	BXGT005136	Low-density lipoprotein receptor-related protein 6	4040	reviewed
O94788	BXGT005333	Retinal dehydrogenase 2	8854	reviewed	Enzyme
O95477	BXGT005383	Phospholipid-transporting ATPase ABCA1	19	reviewed	Transporter
P00492	BXGT005556	Hypoxanthine-guanine phosphoribosyltransferase	3251	reviewed	Enzyme
P01137	BXGT005737	Transforming growth factor beta-1 proprotein	7040	reviewed	Signaling
P01189	BXGT005742	Pro-opiomelanocortin	5443	reviewed
P01375	BXGT005753	Tumor necrosis factor	7124	reviewed	Signaling
P01584	BXGT005772	Interleukin-1 beta	3553	reviewed
P01889	BXGT005809	HLA class I histocompatibility antigen, B-7 alpha chain	3106	reviewed
P02549	BXGT005890	Spectrin alpha chain, erythrocytic 1	6708	reviewed
P02649	BXGT005909	Apolipoprotein E	348	reviewed
P02730	BXGT005935	Band 3 anion transport protein	6521	reviewed	Transporter
P02741	BXGT005936	C-reactive protein	1401	reviewed
P04908	BXGT006283	Histone H2A type 1-B/E	8335	reviewed	Nucleic acid binding
P05091	BXGT006312	Aldehyde dehydrogenase, mitochondrial	217	reviewed	Enzyme
P05181	BXGT006337	Cytochrome P450 2E1	1571	reviewed
P05231	BXGT006345	Interleukin-6	3569	reviewed
P06213	BXGT006425	Insulin receptor	3643	reviewed	Kinase
P06702	BXGT006476	Protein S100-A9	6280	reviewed	Calcium-binding protein
P07438	BXGT006625	Metallothionein-1B	4490	reviewed
P08069	BXGT006723	Insulin-like growth factor 1 receptor	3480	reviewed	Kinase
P10145	BXGT007542	Interleukin-8	3576	reviewed	Signaling
P10415	BXGT007567	Apoptosis regulator Bcl-2	596	reviewed	Signaling
P10632	BXGT007592	Cytochrome P450 2C8	1558	reviewed
P10826	BXGT007622	Retinoic acid receptor beta	5915	reviewed	Nuclear receptor
P11217	BXGT007674	Glycogen phosphorylase, muscle form	5837	reviewed	Enzyme
P11473	BXGT007709	Vitamin D3 receptor	7421	reviewed	Nuclear receptor
P13500	BXGT007916	C-C motif chemokine 2	6347	reviewed	Signaling
P13569	BXGT007923	Cystic fibrosis transmembrane conductance regulator	1080	reviewed	Ion channel
P14210	BXGT007994	Hepatocyte growth factor	3082	reviewed	Enzyme
P15941	BXGT008176	Mucin-1	4582	reviewed
P16157	BXGT008203	Ankyrin-1	286	reviewed
P17252	BXGT008294	Protein kinase C alpha type	5578	reviewed	Kinase
P21802	BXGT008691	Fibroblast growth factor receptor 2	2263	reviewed	Kinase
P23468	BXGT008870	Receptor-type tyrosine-protein phosphatase delta	5789	reviewed	Enzyme
P27037	BXGT009153	Activin receptor type-2A	92	reviewed	Kinase
P30411	BXGT009424	B2 bradykinin receptor	624	reviewed	G-protein coupled receptor
P42685	BXGT010332	Tyrosine-protein kinase FRK	2444	reviewed	Kinase
P47989	BXGT010602	Xanthine dehydrogenase/oxidase	7498	reviewed	Enzyme
P49116	BXGT010678	Nuclear receptor subfamily 2 group C member 2	7182	reviewed	Nuclear receptor
P51787	BXGT010889	Potassium voltage-gated channel subfamily KQT member 1	3784	reviewed	Ion channel
P55157	BXGT011108	Microsomal triglyceride transfer protein large subunit	4547	reviewed	Transporter
P60891	BXGT011337	Ribose-phosphate pyrophosphokinase 1	5631	reviewed	Kinase
P62807	BXGT011458	Histone H2B type 1-C/E/F/G/I	8347	reviewed
Q03181	BXGT012701	Peroxisome proliferator-activated receptor delta	5467	reviewed	Nuclear receptor
Q09428	BXGT013036	ATP-binding cassette sub-family C member 8	6833	reviewed	Transporter
Q12851	BXGT013271	Mitogen-activated protein kinase kinase kinase kinase 2	5871	reviewed	Kinase
Q13237	BXGT013331	cGMP-dependent protein kinase 2	5593	reviewed	Kinase
Q13563	BXGT013377	Polycystin-2	5311	reviewed	Ion channel
Q13733	BXGT013394	Sodium/potassium-transporting ATPase subunit alpha-4	480	reviewed	Transporter
Q14116	BXGT013442	Interleukin-18	3606	reviewed
Q14123	BXGT013445	Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C	5137	reviewed
Q14397	BXGT013467	Glucokinase regulatory protein	2646	reviewed
Q14541	BXGT013481	Hepatocyte nuclear factor 4-gamma	3174	reviewed	Nuclear receptor
Q15036	BXGT013526	Sorting nexin-17	9784	reviewed
Q15848	BXGT013609	Adiponectin	9370	reviewed
Q16584	BXGT013642	Mitogen-activated protein kinase kinase kinase 11	4296	reviewed	Kinase
Q16659	BXGT013652	Mitogen-activated protein kinase 6	5597	reviewed	Kinase
Q30201	BXGT014297	Hereditary hemochromatosis protein	3077	reviewed
Q6PI48	BXGT016471	Aspartate--tRNA ligase, mitochondrial	55157	reviewed	Enzyme
Q92993	BXGT019403	Histone acetyltransferase KAT5	10524	reviewed
Q96EB6	BXGT019646	NAD-dependent protein deacetylase sirtuin-1	23411	reviewed	Epigenetic regulator
Q96QV6	BXGT019723	Histone H2A type 1-A	221613	reviewed	Nucleic acid binding
Q96S37	BXGT019737	Solute carrier family 22 member 12	116085	reviewed	Transporter
Q99700	BXGT019949	Ataxin-2	6311	reviewed	Nucleic acid binding
Q9BWU0	BXGT020155	Kanadaptin	22950	reviewed
Q9NSA0	BXGT021202	Solute carrier family 22 member 11	55867	reviewed	Transporter
Q9NWB1	BXGT021231	RNA binding protein fox-1 homolog 1	54715	reviewed	Nucleic acid binding
Q9UGJ0	BXGT021683	5'-AMP-activated protein kinase subunit gamma-2	51422	reviewed	Enzyme modulator
Q9UNQ0	BXGT021792	ATP-binding cassette sub-family G member 2	9429	reviewed	Transporter
Q9UQB8	BXGT021809	Brain-specific angiogenesis inhibitor 1-associated protein 2	10458	reviewed	Receptor
Q9Y289	BXGT022226	Sodium-dependent multivitamin transporter	8884	reviewed	Transporter
Q9Y694	BXGT022321	Solute carrier family 22 member 7	10864	reviewed	Transporter
Q5T2W1	BXGT023979	Na(+)/H(+) exchange regulatory cofactor NHE-RF3	5174	reviewed
Q9BQ69	BXGT026098	ADP-ribose glycohydrolase MACROD1	28992	reviewed

The disease-related compounds

Compounds

BXGC Id	Compound Name	Structure	Molecular Weight	Number of targets^{?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease}

The disease-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compounds in food^{?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease}