Showing entry for Hypertrophic obstructive cardiomyopathy


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Disease Information
BXGD IdBXGD023303
Disease NameHypertrophic obstructive cardiomyopathy
Disease CUI IdC4551472
MeSH Codes C14  
Disease Class NameCardiovascular Diseases
Semantic TypeDisease or Syndrome
Human Phenotype Ontology Id   
Human Phenotype Ontology Term
Disease Ontology Id DOID:7  
Disease Ontology Class Namedisease of anatomical entity
Disorder Network disorder-protein-compound-food associations
The  disease-related  target proteins
Proteins
Uniport Id BXGT Id Protein Name Gene Status Protein Class
Uniport Id BXGT Id Protein name Gene Status Protein class
A0A024RAV5 BXGT000013 V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog, isoform CRA_b 3845 unreviewed
O00206 BXGT003894 Toll-like receptor 4 7099 reviewed
O00329 BXGT003909 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform 5293 reviewed Kinase
O00767 BXGT003949 Acyl-CoA desaturase 6319 reviewed
O15120 BXGT004129 1-acyl-sn-glycerol-3-phosphate acyltransferase beta 10555 reviewed
O43451 BXGT004594 Maltase-glucoamylase, intestinal 8972 reviewed Enzyme
O60260 BXGT004864 E3 ubiquitin-protein ligase parkin 5071 reviewed Enzyme
O60313 BXGT004871 Dynamin-like 120 kDa protein, mitochondrial 4976 reviewed Enzyme modulator
O75164 BXGT005104 Lysine-specific demethylase 4A 9682 reviewed
O75347 BXGT005113 Tubulin-specific chaperone A 6902 reviewed Chaperone
O75880 BXGT005158 Protein SCO1 homolog, mitochondrial 6341 reviewed Enzyme
O95390 BXGT005377 Growth/differentiation factor 11 10220 reviewed Signaling
P00156 BXGT005469 Cytochrome b 4519 reviewed
P00797 BXGT005658 Renin 5972 reviewed Enzyme
P01019 BXGT005717 Angiotensinogen 183 reviewed Enzyme modulator
P01106 BXGT005730 Myc proto-oncogene protein 4609 reviewed Transcription factor
P01112 BXGT005732 GTPase HRas 3265 reviewed Enzyme modulator
P01116 BXGT005733 GTPase KRas 3845 reviewed Enzyme modulator
P01137 BXGT005737 Transforming growth factor beta-1 proprotein 7040 reviewed Signaling
P01189 BXGT005742 Pro-opiomelanocortin 5443 reviewed
P01308 BXGT005749 Insulin 3630 reviewed
P01375 BXGT005753 Tumor necrosis factor 7124 reviewed Signaling
P02462 BXGT005881 Collagen alpha-1(IV) chain 1282 reviewed
P02511 BXGT005885 Alpha-crystallin B chain 1410 reviewed
P02545 BXGT005889 Prelamin-A/C 4000 reviewed
P02741 BXGT005936 C-reactive protein 1401 reviewed
P02766 BXGT005953 Transthyretin 7276 reviewed Transporter
P03886 BXGT006108 NADH-ubiquinone oxidoreductase chain 1 4535 reviewed Enzyme
P04049 BXGT006133 RAF proto-oncogene serine/threonine-protein kinase 5894 reviewed Kinase
P04275 BXGT006180 von Willebrand factor 7450 reviewed Enzyme modulator
P04637 BXGT006243 Cellular tumor antigen p53 7157 reviewed Transcription factor
P04792 BXGT006264 Heat shock protein beta-1 3315 reviewed
P06213 BXGT006425 Insulin receptor 3643 reviewed Kinase
P06280 BXGT006433 Alpha-galactosidase A 2717 reviewed
P06753 BXGT006498 Tropomyosin alpha-3 chain 7170 reviewed Cellular structure
P07741 BXGT006666 Adenine phosphoribosyltransferase 353 reviewed
P08253 BXGT006757 72 kDa type IV collagenase 4313 reviewed Enzyme
P09001 BXGT006848 39S ribosomal protein L3, mitochondrial 11222 reviewed
P09493 BXGT006900 Tropomyosin alpha-1 chain 7168 reviewed Cellular structure
P10144 BXGT007541 Granzyme B 3002 reviewed Enzyme
P10253 BXGT007550 Lysosomal alpha-glucosidase 2548 reviewed Enzyme
P10599 BXGT007583 Thioredoxin 7295 reviewed
P10809 BXGT007617 60 kDa heat shock protein, mitochondrial 3329 reviewed
P12821 BXGT007849 Angiotensin-converting enzyme 1636 reviewed Enzyme
P13866 BXGT007963 Sodium/glucose cotransporter 1 6523 reviewed Transporter
P14410 BXGT008009 Sucrase-isomaltase, intestinal 6476 reviewed Enzyme
P14780 BXGT008053 Matrix metalloproteinase-9 4318 reviewed Enzyme
P15056 BXGT008075 Serine/threonine-protein kinase B-raf 673 reviewed Kinase
P15531 BXGT008136 Nucleoside diphosphate kinase A 4830 reviewed Kinase
P16066 BXGT008185 Atrial natriuretic peptide receptor 1 4881 reviewed Kinase
P17931 BXGT008356 Galectin-3 3958 reviewed Signaling
P17936 BXGT008357 Insulin-like growth factor-binding protein 3 3486 reviewed Enzyme modulator
P18206 BXGT008389 Vinculin 7414 reviewed
P19404 BXGT008477 NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial 4729 reviewed
P19429 BXGT008479 Troponin I, cardiac muscle 7137 reviewed Cellular structure
P19634 BXGT008504 Sodium/hydrogen exchanger 1 6548 reviewed Transporter
P20472 BXGT008578 Parvalbumin alpha 5816 reviewed Calcium-binding protein
P23946 BXGT008932 Chymase 1215 reviewed Enzyme
P24723 BXGT008989 Protein kinase C eta type 5583 reviewed Kinase
P28331 BXGT009252 NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial 4719 reviewed Enzyme
P29474 BXGT009352 Nitric oxide synthase, endothelial 4846 reviewed
P30556 BXGT009441 Type-1 angiotensin II receptor 185 reviewed G-protein coupled receptor
P30988 BXGT009491 Calcitonin receptor 799 reviewed G-protein coupled receptor
P31749 BXGT009574 RAC-alpha serine/threonine-protein kinase 207 reviewed Kinase
P37231 BXGT009972 Peroxisome proliferator-activated receptor gamma 5468 reviewed Nuclear receptor
P38398 BXGT010037 Breast cancer type 1 susceptibility protein 672 reviewed Enzyme
P41252 BXGT010245 Isoleucine--tRNA ligase, cytoplasmic 3376 reviewed Enzyme
P42336 BXGT010302 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform 5290 reviewed Kinase
P42338 BXGT010303 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform 5291 reviewed Kinase
P42345 BXGT010304 Serine/threonine-protein kinase mTOR 2475 reviewed Kinase
P45379 BXGT010459 Troponin T, cardiac muscle 7139 reviewed Cellular structure
P48735 BXGT010657 Isocitrate dehydrogenase [NADP], mitochondrial 3418 reviewed
P48736 BXGT010658 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform 5294 reviewed Kinase
P49327 BXGT010694 Fatty acid synthase 2194 reviewed Enzyme
P49748 BXGT010733 Very long-chain specific acyl-CoA dehydrogenase, mitochondrial 37 reviewed Enzyme
P50052 BXGT010768 Type-2 angiotensin II receptor 186 reviewed G-protein coupled receptor
P51532 BXGT010852 Transcription activator BRG1 6597 reviewed Epigenetic regulator
P51787 BXGT010889 Potassium voltage-gated channel subfamily KQT member 1 3784 reviewed Ion channel
P60709 BXGT011322 Actin, cytoplasmic 1 60 reviewed Cellular structure
P62508 BXGT011431 Estrogen-related receptor gamma 2104 reviewed Nuclear receptor
P62736 BXGT011452 Actin, aortic smooth muscle 59 reviewed Cellular structure
P63316 BXGT011517 Troponin C, slow skeletal and cardiac muscles 7134 reviewed Calcium-binding protein
P68133 BXGT011578 Actin, alpha skeletal muscle 58 reviewed Cellular structure
P78536 BXGT011847 Disintegrin and metalloproteinase domain-containing protein 17 6868 reviewed
Q01094 BXGT012568 Transcription factor E2F1 1869 reviewed Nucleic acid binding
Q02750 BXGT012662 Dual specificity mitogen-activated protein kinase kinase 1 5604 reviewed Kinase
Q03164 BXGT012700 Histone-lysine N-methyltransferase 2A 4297 reviewed
Q06124 BXGT012856 Tyrosine-protein phosphatase non-receptor type 11 5781 reviewed
Q07889 BXGT012946 Son of sevenless homolog 1 6654 reviewed Enzyme modulator
Q09013 BXGT013023 Myotonin-protein kinase 1760 reviewed Kinase
Q13085 BXGT013309 Acetyl-CoA carboxylase 1 31 reviewed
Q13093 BXGT013310 Platelet-activating factor acetylhydrolase 7941 reviewed Enzyme
Q13118 BXGT013312 Krueppel-like factor 10 7071 reviewed Nucleic acid binding
Q13131 BXGT013314 5'-AMP-activated protein kinase catalytic subunit alpha-1 5562 reviewed Kinase
Q13315 BXGT013339 Serine-protein kinase ATM 472 reviewed Kinase
Q13427 BXGT013354 Peptidyl-prolyl cis-trans isomerase G 9360 reviewed
Q13467 BXGT013358 Frizzled-5 7855 reviewed G-protein coupled receptor
Q13936 BXGT013404 Voltage-dependent L-type calcium channel subunit alpha-1C 775 reviewed Ion channel
Q14116 BXGT013442 Interleukin-18 3606 reviewed
Q14126 BXGT013446 Desmoglein-2 1829 reviewed Cell adhesion
Q14315 BXGT013460 Filamin-C 2318 reviewed
Q14683 BXGT013500 Structural maintenance of chromosomes protein 1A 8243 reviewed
Q15046 BXGT013527 Lysine--tRNA ligase 3735 reviewed Enzyme
Q15831 BXGT013604 Serine/threonine-protein kinase STK11 6794 reviewed Kinase
Q16584 BXGT013642 Mitogen-activated protein kinase kinase kinase 11 4296 reviewed Kinase
Q16595 BXGT013643 Frataxin, mitochondrial 2395 reviewed Enzyme
Q5VST9 BXGT015886 Obscurin 84033 reviewed Kinase
Q7Z406 BXGT017251 Myosin-14 79784 reviewed
Q8NBP7 BXGT018541 Proprotein convertase subtilisin/kexin type 9 255738 reviewed Enzyme
Q8NEB9 BXGT018553 Phosphatidylinositol 3-kinase catalytic subunit type 3 5289 reviewed Kinase
Q8WZ42 BXGT019023 Titin 7273 reviewed Kinase
Q92736 BXGT019367 Ryanodine receptor 2 6262 reviewed Ion channel
Q92769 BXGT019370 Histone deacetylase 2 3066 reviewed Epigenetic regulator
Q92905 BXGT019393 COP9 signalosome complex subunit 5 10987 reviewed Enzyme
Q92963 BXGT019401 GTP-binding protein Rit1 6016 reviewed Enzyme modulator
Q969Q1 BXGT019610 E3 ubiquitin-protein ligase TRIM63 84676 reviewed
Q96AC1 BXGT019617 Fermitin family homolog 2 10979 reviewed
Q96HC4 BXGT019671 PDZ and LIM domain protein 5 10611 reviewed Cellular structure
Q99572 BXGT019935 P2X purinoceptor 7 5027 reviewed Ion channel
Q99873 BXGT019972 Protein arginine N-methyltransferase 1 3276 reviewed Epigenetic regulator
Q9BUP3 BXGT020137 Oxidoreductase HTATIP2 10553 reviewed
Q9BYF1 BXGT020186 Angiotensin-converting enzyme 2 59272 reviewed Enzyme
Q9H7Z6 BXGT020493 Histone acetyltransferase KAT8 84148 reviewed
Q9NSE4 BXGT021207 Isoleucine--tRNA ligase, mitochondrial 55699 reviewed Enzyme
Q9P0K1 BXGT021288 Disintegrin and metalloproteinase domain-containing protein 22 53616 reviewed Enzyme
Q9UGJ0 BXGT021683 5'-AMP-activated protein kinase subunit gamma-2 51422 reviewed Enzyme modulator
Q9Y3Q4 BXGT022264 Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 10021 reviewed Ion channel
Q9Y5Y9 BXGT022309 Sodium channel protein type 10 subunit alpha 6336 reviewed Ion channel
P04439 BXGT022649 HLA class I histocompatibility antigen, A-3 alpha chain 3105 reviewed
O60936 BXGT022857 Nucleolar protein 3 8996 reviewed
P08123 BXGT024477 Collagen alpha-2(I) chain 1278 reviewed
The  disease-related  compounds
Compounds
BXGC Id Compound Name Structure Molecular Weight Number of targets?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease
The  disease-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compounds in food?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease