Showing entry for Increased tendency to bruise


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Disease Information
BXGD IdBXGD008510
Disease NameIncreased tendency to bruise
Disease CUI IdC0423798
MeSH Codes C26  
Disease Class NameWounds and Injuries
Semantic TypeFinding
Human Phenotype Ontology Id HP:0001574   HP:0001871   HP:0001626  
Human Phenotype Ontology TermAbnormality of the integument; Abnormality of blood and blood-forming tissues; Abnormality of the cardiovascular system
Disease Ontology Id   
Disease Ontology Class Name
Disorder Network disorder-protein-compound-food associations
The  disease-related  target proteins
Proteins
Uniport Id BXGT Id Protein Name Gene Status Protein Class
Uniport Id BXGT Id Protein name Gene Status Protein class
O14788 BXGT004100 Tumor necrosis factor ligand superfamily member 11 8600 reviewed Signaling
O60568 BXGT004885 Multifunctional procollagen lysine hydroxylase and glycosyltransferase LH3 8985 reviewed Enzyme
O60674 BXGT004892 Tyrosine-protein kinase JAK2 3717 reviewed Kinase
O95255 BXGT005363 Multidrug resistance-associated protein 6 368 reviewed Transporter
O95267 BXGT005368 RAS guanyl-releasing protein 1 10125 reviewed Enzyme modulator
P00451 BXGT005545 Coagulation factor VIII 2157 reviewed Enzyme
P00488 BXGT005552 Coagulation factor XIII A chain 2162 reviewed Enzyme
P00734 BXGT005630 Prothrombin 2147 reviewed Enzyme
P00736 BXGT005632 Complement C1r subcomponent 715 reviewed Enzyme
P00742 BXGT005636 Coagulation factor X 2159 reviewed Enzyme
P00749 BXGT005641 Urokinase-type plasminogen activator 5328 reviewed Enzyme
P02452 BXGT005878 Collagen alpha-1(I) chain 1277 reviewed
P02461 BXGT005880 Collagen alpha-1(III) chain 1281 reviewed
P02533 BXGT005887 Keratin, type I cytoskeletal 14 3861 reviewed
P04062 BXGT006140 Lysosomal acid glucosylceramidase 2629 reviewed
P04275 BXGT006180 von Willebrand factor 7450 reviewed Enzyme modulator
P05106 BXGT006315 Integrin beta-3 3690 reviewed Receptor
P05160 BXGT006330 Coagulation factor XIII B chain 2165 reviewed
P06396 BXGT006435 Gelsolin 2934 reviewed Cellular structure
P06748 BXGT006497 Nucleophosmin 4869 reviewed Chaperone
P07359 BXGT006612 Platelet glycoprotein Ib alpha chain 2811 reviewed Receptor
P08514 BXGT006781 Integrin alpha-IIb 3674 reviewed
P08697 BXGT006815 Alpha-2-antiplasmin 5345 reviewed Enzyme modulator
P08709 BXGT006818 Coagulation factor VII 2155 reviewed Enzyme
P09871 BXGT006932 Complement C1s subcomponent 716 reviewed Enzyme
P10276 BXGT007553 Retinoic acid receptor alpha 5914 reviewed Nuclear receptor
P10600 BXGT007584 Transforming growth factor beta-3 proprotein 7043 reviewed Signaling
P10644 BXGT007597 cAMP-dependent protein kinase type I-alpha regulatory subunit 5573 reviewed
P13224 BXGT007890 Platelet glycoprotein Ib beta chain 2812 reviewed
P13647 BXGT007937 Keratin, type II cytoskeletal 5 3852 reviewed
P15056 BXGT008075 Serine/threonine-protein kinase B-raf 673 reviewed Kinase
P17301 BXGT008299 Integrin alpha-2 3673 reviewed
P17612 BXGT008322 cAMP-dependent protein kinase catalytic subunit alpha 5566 reviewed Kinase
P19438 BXGT008480 Tumor necrosis factor receptor superfamily member 1A 7132 reviewed
P21333 BXGT008638 Filamin-A 2316 reviewed
P22413 BXGT008764 Ectonucleotide pyrophosphatase/phosphodiesterase family member 1 5167 reviewed Enzyme
P24557 BXGT008976 Thromboxane-A synthase 6916 reviewed
P28300 BXGT009243 Protein-lysine 6-oxidase 4015 reviewed
P31153 BXGT009512 S-adenosylmethionine synthase isoform type-2 4144 reviewed Enzyme
P35555 BXGT009845 Fibrillin-1 2200 reviewed Calcium-binding protein
P35579 BXGT009852 Myosin-9 4627 reviewed
P36897 BXGT009941 TGF-beta receptor type-1 7046 reviewed Kinase
P37173 BXGT009970 TGF-beta receptor type-2 7048 reviewed Kinase
P38435 BXGT010040 Vitamin K-dependent gamma-carboxylase 2677 reviewed
P40763 BXGT010202 Signal transducer and activator of transcription 3 6774 reviewed Nucleic acid binding
P41212 BXGT010235 Transcription factor ETV6 2120 reviewed Transcription factor
P46100 BXGT010508 Transcriptional regulator ATRX 546 reviewed
P48023 BXGT010604 Tumor necrosis factor ligand superfamily member 6 356 reviewed Signaling
P51692 BXGT010885 Signal transducer and activator of transcription 5B 6777 reviewed Nucleic acid binding
P62736 BXGT011452 Actin, aortic smooth muscle 59 reviewed Cellular structure
P63092 BXGT011495 Guanine nucleotide-binding protein G(s) subunit alpha isoforms short 2778 reviewed
P69905 BXGT011649 Hemoglobin subunit alpha 3040 reviewed
P84022 BXGT012027 Mothers against decapentaplegic homolog 3 4088 reviewed Transcription factor
Q01196 BXGT012575 Runt-related transcription factor 1 861 reviewed Transcription factor
Q02809 BXGT012674 Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1 5351 reviewed Enzyme
Q05516 BXGT012822 Zinc finger and BTB domain-containing protein 16 7704 reviewed Transcription factor
Q05655 BXGT012832 Protein kinase C delta type 5580 reviewed Kinase
Q06124 BXGT012856 Tyrosine-protein phosphatase non-receptor type 11 5781 reviewed
Q13976 BXGT013409 cGMP-dependent protein kinase 1 5592 reviewed Kinase
Q14004 BXGT013435 Cyclin-dependent kinase 13 8621 reviewed Kinase
Q14108 BXGT013440 Lysosome membrane protein 2 950 reviewed Receptor
Q15149 BXGT013547 Plectin 5339 reviewed Cellular structure
Q15746 BXGT013591 Myosin light chain kinase, smooth muscle 4638 reviewed Kinase
Q6N021 BXGT016378 Methylcytosine dioxygenase TET2 54790 reviewed
Q92963 BXGT019401 GTP-binding protein Rit1 6016 reviewed Enzyme modulator
Q9H244 BXGT020448 P2Y purinoceptor 12 64805 reviewed G-protein coupled receptor
Q9H251 BXGT020449 Cadherin-23 64072 reviewed
Q9HCN6 BXGT020535 Platelet glycoprotein VI 51206 reviewed Receptor
Q9HCR9 BXGT020537 Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A 50940 reviewed
Q9NWM8 BXGT021233 Peptidyl-prolyl cis-trans isomerase FKBP14 55033 reviewed
Q9Y2K2 BXGT022238 Serine/threonine-protein kinase SIK3 23387 reviewed Kinase
Q9Y5X0 BXGT022305 Sorting nexin-10 29887 reviewed
P35670 BXGT023695 Copper-transporting ATPase 2 540 reviewed Transporter
P29590 BXGT024350 Protein PML 5371 reviewed
P08123 BXGT024477 Collagen alpha-2(I) chain 1278 reviewed
Q14980 BXGT025336 Nuclear mitotic apparatus protein 1 4926 reviewed
P51798 BXGT026083 H(+)/Cl(-) exchange transporter 7 1186 reviewed Ion channel
P21731 BXGT026174 Thromboxane A2 receptor 6915 reviewed G-protein coupled receptor
The  disease-related  compounds
Compounds
BXGC Id Compound Name Structure Molecular Weight Number of targets?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease
The  disease-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compounds in food?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease