adisease

Showing entry for Proteinuria

General Disease Information
BXGD Id	BXGD002415
Disease Name	Proteinuria
Disease CUI Id	C0033687
MeSH Codes	C23 C13 C12
Disease Class Name	Pathological Conditions, Signs and Symptoms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
Semantic Type	Finding
Human Phenotype Ontology Id	HP:0001939 HP:0000119
Human Phenotype Ontology Term	Abnormality of metabolism/homeostasis; Abnormality of the genitourinary system
Disease Ontology Id	DOID:7
Disease Ontology Class Name	disease of anatomical entity
Disorder Network	disorder-protein-compound-food associations

The disease-related target proteins

Proteins

Uniport Id	BXGT Id	Protein Name	Gene	Status	Protein Class
Uniport Id	BXGT Id	Protein name	Gene	Status	Protein class
O14791	BXGT004101	Apolipoprotein L1	8542	reviewed	Transporter
O15305	BXGT004152	Phosphomannomutase 2	5373	reviewed	Enzyme
O15553	BXGT004181	Pyrin	4210	reviewed
O43272	BXGT004580	Proline dehydrogenase 1, mitochondrial	5625	reviewed	Enzyme
O43639	BXGT004608	Cytoplasmic protein NCK2	8440	reviewed
O43707	BXGT004616	Alpha-actinin-4	81	reviewed
O43826	BXGT004629	Glucose-6-phosphate exchanger SLC37A4	2542	reviewed	Transporter
O60488	BXGT004878	Long-chain-fatty-acid--CoA ligase 4	2182	reviewed	Enzyme
O60494	BXGT004879	Cubilin	8029	reviewed
O60931	BXGT004911	Cystinosin	1497	reviewed
O75880	BXGT005158	Protein SCO1 homolog, mitochondrial	6341	reviewed	Enzyme
O95470	BXGT005382	Sphingosine-1-phosphate lyase 1	8879	reviewed
P00441	BXGT005540	Superoxide dismutase [Cu-Zn]	6647	reviewed	Enzyme
P00736	BXGT005632	Complement C1r subcomponent	715	reviewed	Enzyme
P00751	BXGT005643	Complement factor B	629	reviewed
P00797	BXGT005658	Renin	5972	reviewed	Enzyme
P01009	BXGT005714	Alpha-1-antitrypsin	5265	reviewed	Enzyme modulator
P01019	BXGT005717	Angiotensinogen	183	reviewed	Enzyme modulator
P01024	BXGT005719	Complement C3	718	reviewed	Enzyme modulator
P01137	BXGT005737	Transforming growth factor beta-1 proprotein	7040	reviewed	Signaling
P01189	BXGT005742	Pro-opiomelanocortin	5443	reviewed
P01579	BXGT005770	Interferon gamma	3458	reviewed
P01889	BXGT005809	HLA class I histocompatibility antigen, B-7 alpha chain	3106	reviewed
P01909	BXGT005815	HLA class II histocompatibility antigen, DQ alpha 1 chain	3117	reviewed	Immune response
P01911	BXGT005816	HLA class II histocompatibility antigen, DRB1-15 beta chain	3123	reviewed	Immune response
P02647	BXGT005908	Apolipoprotein A-I	335	reviewed
P02649	BXGT005909	Apolipoprotein E	348	reviewed
P02671	BXGT005914	Fibrinogen alpha chain	2243	reviewed
P02751	BXGT005943	Fibronectin	2335	reviewed	Signaling
P02768	BXGT005955	Serum albumin	213	reviewed	Transporter
P03886	BXGT006108	NADH-ubiquinone oxidoreductase chain 1	4535	reviewed	Enzyme
P03905	BXGT006113	NADH-ubiquinone oxidoreductase chain 4	4538	reviewed	Enzyme
P03915	BXGT006114	NADH-ubiquinone oxidoreductase chain 5	4540	reviewed	Enzyme
P03923	BXGT006115	NADH-ubiquinone oxidoreductase chain 6	4541	reviewed
P04004	BXGT006125	Vitronectin	7448	reviewed
P04062	BXGT006140	Lysosomal acid glucosylceramidase	2629	reviewed
P04180	BXGT006164	Phosphatidylcholine-sterol acyltransferase	3931	reviewed	Enzyme
P04440	BXGT006216	HLA class II histocompatibility antigen, DP beta 1 chain	3115	reviewed	Immune response
P04839	BXGT006273	Cytochrome b-245 heavy chain	1536	reviewed	Ion channel
P05156	BXGT006329	Complement factor I	3426	reviewed
P05362	BXGT006350	Intercellular adhesion molecule 1	3383	reviewed
P06213	BXGT006425	Insulin receptor	3643	reviewed	Kinase
P06280	BXGT006433	Alpha-galactosidase A	2717	reviewed
P06396	BXGT006435	Gelsolin	2934	reviewed	Cellular structure
P07204	BXGT006567	Thrombomodulin	7056	reviewed
P07711	BXGT006661	Cathepsin L1	1514	reviewed	Enzyme
P07858	BXGT006689	Cathepsin B	1508	reviewed	Enzyme
P07949	BXGT006703	Proto-oncogene tyrosine-protein kinase receptor Ret	5979	reviewed	Kinase
P08174	BXGT006739	Complement decay-accelerating factor	1604	reviewed
P08235	BXGT006751	Mineralocorticoid receptor	4306	reviewed	Nuclear receptor
P08236	BXGT006752	Beta-glucuronidase	2990	reviewed
P08603	BXGT006798	Complement factor H	3075	reviewed
P09601	BXGT006909	Heme oxygenase 1	3162	reviewed
P10646	BXGT007598	Tissue factor pathway inhibitor	7035	reviewed	Enzyme modulator
P10909	BXGT007630	Clusterin	1191	reviewed
P12821	BXGT007849	Angiotensin-converting enzyme	1636	reviewed	Enzyme
P13671	BXGT007941	Complement component C6	729	reviewed
P13726	BXGT007950	Tissue factor	2152	reviewed	Receptor
P15529	BXGT008134	Membrane cofactor protein	4179	reviewed
P15692	BXGT008147	Vascular endothelial growth factor A	7422	reviewed	Signaling
P16333	BXGT008219	Cytoplasmic protein NCK1	4690	reviewed
P16410	BXGT008224	Cytotoxic T-lymphocyte protein 4	1493	reviewed
P17948	BXGT008358	Vascular endothelial growth factor receptor 1	2321	reviewed	Kinase
P18827	BXGT008427	Syndecan-1	6382	reviewed	Extracellular structure
P19544	BXGT008494	Wilms tumor protein	7490	reviewed	Nucleic acid binding
P19634	BXGT008504	Sodium/hydrogen exchanger 1	6548	reviewed	Transporter
P20292	BXGT008561	Arachidonate 5-lipoxygenase-activating protein	241	reviewed	Enzyme
P22736	BXGT008800	Nuclear receptor subfamily 4 group A member 1	3164	reviewed	Nuclear receptor
P24158	BXGT008951	Myeloblastin	5657	reviewed	Enzyme
P24855	BXGT008998	Deoxyribonuclease-1	1773	reviewed
P27487	BXGT009187	Dipeptidyl peptidase 4	1803	reviewed	Enzyme
P29400	BXGT009343	Collagen alpha-5(IV) chain	1287	reviewed
P29474	BXGT009352	Nitric oxide synthase, endothelial	4846	reviewed
P30556	BXGT009441	Type-1 angiotensin II receptor	185	reviewed	G-protein coupled receptor
P31040	BXGT009503	Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial	6389	reviewed	Enzyme
P35354	BXGT009816	Prostaglandin G/H synthase 2	5743	reviewed	Enzyme
P35579	BXGT009852	Myosin-9	4627	reviewed
P37088	BXGT009961	Amiloride-sensitive sodium channel subunit alpha	6337	reviewed	Ion channel
P40337	BXGT010174	von Hippel-Lindau disease tumor suppressor	7428	reviewed	Enzyme
P40926	BXGT010207	Malate dehydrogenase, mitochondrial	4191	reviewed	Enzyme
P41235	BXGT010241	Hepatocyte nuclear factor 4-alpha	3172	reviewed	Nuclear receptor
P43403	BXGT010385	Tyrosine-protein kinase ZAP-70	7535	reviewed	Kinase
P48357	BXGT010627	Leptin receptor	3953	reviewed	Signaling
P51617	BXGT010868	Interleukin-1 receptor-associated kinase 1	3654	reviewed	Kinase
P51795	BXGT010891	H(+)/Cl(-) exchange transporter 5	1184	reviewed	Ion channel
P52565	BXGT010933	Rho GDP-dissociation inhibitor 1	396	reviewed	Enzyme modulator
P53667	BXGT011008	LIM domain kinase 1	3984	reviewed	Kinase
P61586	BXGT011375	Transforming protein RhoA	387	reviewed	Enzyme modulator
P61626	BXGT011382	Lysozyme C	4069	reviewed
P61769	BXGT011383	Beta-2-microglobulin	567	reviewed	Immune response
P62314	BXGT011420	Small nuclear ribonucleoprotein Sm D1	6632	reviewed	Nucleic acid binding
P98164	BXGT012230	Low-density lipoprotein receptor-related protein 2	4036	reviewed
Q01968	BXGT012626	Inositol polyphosphate 5-phosphatase OCRL-1	4952	reviewed	Enzyme
Q03468	BXGT012716	DNA excision repair protein ERCC-6	2074	reviewed
Q04721	BXGT012777	Neurogenic locus notch homolog protein 2	4853	reviewed
Q06830	BXGT012894	Peroxiredoxin-1	5052	reviewed	Enzyme
Q07869	BXGT012945	Peroxisome proliferator-activated receptor alpha	5465	reviewed	Nuclear receptor
Q09328	BXGT013034	Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A	4249	reviewed	Enzyme
Q12965	BXGT013285	Unconventional myosin-Ie	4643	reviewed	Cellular structure
Q13153	BXGT013319	Serine/threonine-protein kinase PAK 1	5058	reviewed	Kinase
Q13177	BXGT013323	Serine/threonine-protein kinase PAK 2	5062	reviewed	Kinase
Q14108	BXGT013440	Lysosome membrane protein 2	950	reviewed	Receptor
Q15848	BXGT013609	Adiponectin	9370	reviewed
Q16827	BXGT013675	Receptor-type tyrosine-protein phosphatase O	5800	reviewed
Q76LX8	BXGT016870	A disintegrin and metalloproteinase with thrombospondin motifs 13	11093	reviewed	Enzyme
Q96AX1	BXGT019620	Vacuolar protein sorting-associated protein 33A	65082	reviewed	Transporter
Q96D42	BXGT019636	Hepatitis A virus cellular receptor 1	26762	reviewed
Q96D53	BXGT019637	Atypical kinase COQ8B, mitochondrial	79934	reviewed	Kinase
Q96S44	BXGT019738	EKC/KEOPS complex subunit TP53RK	112858	reviewed	Kinase
Q99519	BXGT019928	Sialidase-1	4758	reviewed	Enzyme
Q9BYF1	BXGT020186	Angiotensin-converting enzyme 2	59272	reviewed	Enzyme
Q9NRF2	BXGT021185	SH2B adapter protein 1	25970	reviewed
Q9P212	BXGT021297	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1	51196	reviewed	Enzyme
Q9Y251	BXGT022215	Heparanase	10855	reviewed	Enzyme
Q9Y2M0	BXGT022241	Fanconi-associated nuclease 1	22909	reviewed
Q9Y2R2	BXGT022243	Tyrosine-protein phosphatase non-receptor type 22	26191	reviewed
Q9Y4U1	BXGT022285	Methylmalonic aciduria and homocystinuria type C protein	25974	reviewed
P52429	BXGT022667	Diacylglycerol kinase epsilon	8526	reviewed	Enzyme
P20036	BXGT022764	HLA class II histocompatibility antigen, DP alpha 1 chain	3113	reviewed	Immune response
P00738	BXGT022874	Haptoglobin	3240	reviewed	Enzyme
Q01955	BXGT023255	Collagen alpha-3(IV) chain	1285	reviewed
Q63ZY3	BXGT023544	KN motif and ankyrin repeat domain-containing protein 2	25959	reviewed
P00395	BXGT023596	Cytochrome c oxidase subunit 1	4512	reviewed	Enzyme
Q59FF6	BXGT023693	Excision repair cross-complementing rodent repair deficiency, complementation group 6 variant	2074	unreviewed
P35670	BXGT023695	Copper-transporting ATPase 2	540	reviewed	Transporter
Q99958	BXGT023732	Forkhead box protein C2	2303	reviewed	Transcription factor
P07954	BXGT023939	Fumarate hydratase, mitochondrial	2271	reviewed	Enzyme
Q14258	BXGT024016	E3 ubiquitin/ISG15 ligase TRIM25	7706	reviewed
Q14657	BXGT024111	EKC/KEOPS complex subunit LAGE3	8270	reviewed
Q9NPF4	BXGT024113	Probable tRNA N6-adenosine threonylcarbamoyltransferase	55644	reviewed	Enzyme
P57729	BXGT024172	Ras-related protein Rab-38	23682	reviewed
P35250	BXGT025854	Replication factor C subunit 2	5982	reviewed	Enzyme
P00403	BXGT026137	Cytochrome c oxidase subunit 2	4513	reviewed	Enzyme

The disease-related compounds

Compounds

BXGC Id	Compound Name	Structure	Molecular Weight	Number of targets^{?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease}

The disease-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compounds in food^{?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease}